Icyo Etidronate ari cyo: Ibyo ikoreshwa, urugero rwo gufata, ingaruka zayo n'ibindi

Etidronate ni umuti ukomeza amagufa ufasha kwirinda ko amagufa yawe yangirika vuba cyane. Ihereranye n'itsinda ry'imiti yitwa bisphosphonates, ikora nk'ingabo zirinda amagufa yawe mu kugabanya umuvuduko w'isanzwe uyangiza uko igihe kigenda.

Uyu muti umaze imyaka myinshi ufasha abantu kugira amagufa akomeye. Muganga wawe ashobora kukugira inama yo kuyifata niba ufite indwara zimwe na zimwe z'amagufa cyangwa niba ufite ibyago byo kurwara amagufa acika vuba.

Etidronate ikoreshwa mu iki?

Etidronate ivura kandi ikarinda indwara nyinshi zijyanye n'amagufa aho amagufa yawe agera intege nke cyangwa akangirika vuba cyane kuruta uko byagakwiye. Impamvu isanzwe abaganga bandikira uyu muti ni ukugira ngo bafashe abantu barwaye indwara ya Paget, indwara aho amagufa akura mu buryo budasanzwe kandi agahinduka.

Muganga wawe ashobora kandi kugusaba etidronate niba ufite osteoporosis, cyane cyane niba iterwa no gukoresha imiti ya steroid igihe kirekire. Abantu bamwe bayifata kugira ngo birinde gutakaza amagufa nyuma yo kuvurwa mu buryo bw'ubuvuzi cyangwa kubagwa bishobora guteza intege nke amagufa.

Mu buryo butavugwa cyane, abaganga bandikira etidronate abantu bagira calcium yiyongera mu bice byabo byoroshye, indwara yitwa heterotopic ossification. Ibi bishobora kubaho nyuma yo kubagwa mu kuguru cyangwa imvune zo mu mugongo.

Etidronate ikora ite?

Etidronate ikora igabanya umuvuduko w'uturemangingo twitwa osteoclasts, dusanzwe dushinzwe gusenya imitsi ya kera y'amagufa. Tekereza amagufa yawe nk'aho ahora yisana, hamwe n'uturemangingo tumwe dusenya amagufa ya kera naho utundi twubaka amagufa mashya.

Iyo ufata etidronate, yifatanya n'amagufa yawe kandi bigatuma bitorohera uturemangingo dusenya gukora akazi kabo. Ibi bituma uturemangingo twubaka amagufa tugira umwanya wo kurema imitsi mishya, ikomeye y'amagufa.

Ku bijyanye n'imiti y'amagufa, etidronate ifatwa nk'uburyo bwo hagati mu gukomera. Ntabwo ikomeye nk'andi ma bisphosphonates mashya, ariko imaze imyaka myinshi ikoreshwa neza kandi ikora neza ku bantu benshi.

Nkwiriye Gufata Nte Etidronate?

Gufata etidronate neza ni ngombwa kugira ngo ikore neza kandi itagira ingaruka. Ukeneye kuyifata igihe inda yawe itarimo ikintu, nibura amasaha 2 mbere cyangwa nyuma yo kurya ibyo aribyo byose.

Ibi nibyo bikora neza ku bantu benshi iyo bafata etidronate:

• Yifate mu gitondo kare ukoresheje ikirahure kinini cy'amazi asanzwe
• Guma wicaye cyangwa uhagaze nibura iminota 30 nyuma yo kuyifata
• Ntukarye, ntunywe ikindi kinyobwa kitari amazi, cyangwa ngo ufate indi miti mu gihe cy'amasaha 2
• Irinde amata, ikawa, icyayi, cyangwa umutobe kuko ibi bishobora kubuza umubiri kuyifata neza

Izi ntambwe zifasha umubiri wawe gufata umuti neza kandi zigabanya amahirwe yo kuribwa mu nda. Igihe gishobora kugaragara nk'igikaze, ariko bituma umuti ukora neza.

Nkwiriye Gufata Etidronate Igihe Kingana Gite?

Igihe uvura na etidronate giterwa n'uburwayi bwawe bwihariye n'uburyo umubiri wawe wakiriye umuti. Ku ndwara ya Paget, abantu benshi bayifata amezi 6 icyarimwe, hanyuma bakaruhuka kugira ngo barebe uko amagufa yabo ameze.

Muganga wawe azakurikirana uko urimo urwanya indwara ukoresheje ibizamini by'amaraso bisanzwe ndetse n'ibizamini by'amagufa. Abantu bamwe bakeneye gukoresha umuti rimwe gusa, mu gihe abandi bashobora gukenera gukoresha imiti inshuro nyinshi mu myaka myinshi.

Mugukingira osteoporosis, ibihe byo kuvura birashobora gutandukana cyane. Muganga wawe azatekereza ku bintu nk'imyaka yawe, izindi ndwara, n'uburyo amagufa yawe yakiriye umuti kugira ngo amenye igihe cyiza cyo kuyifata.

Ni Iyihe Ngaruka Ziterwa na Etidronate?

Abantu benshi boroherwa na etidronate, ariko nk'imiti yose, ishobora gutera ingaruka zidakunda. Inkuru nziza ni uko ingaruka zikomeye zitaba kenshi, kandi abantu benshi ntibagira ingaruka na mba.

Ingaruka zisanzwe ushobora kubona zirimo:

• Urugarara cyangwa kubabara mu nda
• Impiswi cyangwa kwituma bireremye
• Uburyohe bwa icyuma mu kanwa kawe
• Umutwe
• Kubabara mu magufwa, mu ngingo, cyangwa mu misitsi

Ibi bimenyetso akenshi biba byoroheje kandi bikagenda bikira uko umubiri wawe umenyera umuti. Gufata etidronate uko byategetswe neza bishobora gufasha kugabanya ingaruka zifitanye isano n'inda.

Ingaruka zikomeye ziraboneka gake ariko ni ngombwa kuzimenya. Zishobora kuba zirimo kubabara cyane mu nda, kugorana kumeza, cyangwa kubabara amagufwa mashya kudashira. Niba ubonye ibyo aribyo byose, vugana na muganga wawe ako kanya.

Gake cyane, abantu bamwe bafata bisphosphonates nka etidronate igihe kirekire bashobora kugira imvune idasanzwe mu gice cy'ikibero cyangwa ibibazo by'amagufwa yo mu ruhanga. Muganga wawe azakugenzura kuri izi ngorane zidasanzwe cyane mu gihe cyo kugenzurwa buri gihe.

Ninde utagomba gufata Etidronate?

Etidronate ntabwo ikwiriye kuri buri wese, kandi muganga wawe azatekereza ibintu byinshi mbere yo kuyandika. Abantu bafite ibibazo bimwe na bimwe by'impyiko ntibagomba gufata uyu muti kuko imibiri yabo itabasha kuwukora neza.

Ugomba kwirinda etidronate niba ugorwa kumeza cyangwa ufite ibibazo by'esophagus (urugingo ruhuza umunwa wawe n'inda yawe). Uyu muti ushobora kurakaza ibi bice niba bigumyeho.

Izindi mimerere aho etidronate itakwiriye zirimo:

• Indwara ikomeye y'impyiko
• Urugero rwo hasi cyane rwa kalisiyumu mu maraso yawe
• Kutabasha kwicara cyangwa guhagarara neza byibura iminota 30
• Ibibazo by'ibisebe by'inda cyangwa kuribwa cyane mu gituza
• Gusama cyangwa konsa

Niba ufite kimwe muri ibi bibazo, muganga wawe ashobora kuganira ku zindi nshuti zishobora gukora neza ku miterere yawe.

Amazina y'ubwoko bwa Etidronate

Etidronate iboneka mu mazina menshi y'ubwoko, Didronel ikaba ari yo isanzwe ubona cyane. Andi mazina y'ubwoko arimo Didrocal, ihuza etidronate na calcium carbonate mu buryo bworoshye bwo kuvura.

Ubundi bwoko bwa etidronate buraboneka kandi bukora neza nk'ubwoko bw'izina. Umuganga wawe w'imiti ashobora kugufasha gusobanukirwa ubwoko urimo kwakira no gusubiza ibibazo byose bijyanye n'imiti yawe yihariye.

Izindi nshuti za Etidronate

Niba etidronate itagukorera neza cyangwa ikaba itera ingaruka, hari izindi miti ikomeza amagufa iboneka. Bisphosphonates nshya nka alendronate (Fosamax) cyangwa risedronate (Actonel) bikora kimwe ariko bishobora gufatwa kenshi.

Ku bantu batabasha gufata imiti yo kunywa, ibisubizo byo guterwa inshinge nka zoledronic acid (Reclast) bitangwa umwaka umwe binyuze muri IV. Abantu bamwe bakunda imiti nka denosumab (Prolia), itangwa nk'urushinge buri mezi atandatu.

Muganga wawe ashobora kandi gutekereza ku kuvura hormone, abahindura ibintu bya estrogen receptor, cyangwa imiti mishya nka teriparatide mu bihe bimwe na bimwe. Guhitamo neza biterwa n'imiterere yawe yihariye, izindi mpamvu z'ubuzima, n'ibyo ukunda.

Ese Etidronate iruta Alendronate?

Byombi etidronate na alendronate ni imiti ikora neza amagufa, ariko ifite itandukaniro rikomeye. Alendronate akenshi ifatwa nk'ikomeye kandi ifatwa kenshi, mugihe etidronate ikoreshwa kenshi mu byiciro hamwe n'ikiruhuko hagati y'imiti.

Alendronate yigishijwe cyane mu gukumira no kuvura osteoporosis, cyane cyane ku bagore bageze mu gihe cyo gucura. Akenshi ni yo ihitamo rya mbere ku bantu benshi bafite osteoporosis kubera iyi shingiro rikomeye ry'ubushakashatsi.

Etidronate ishobora gukundwa ku bibazo bimwe na bimwe nka indwara ya Paget cyangwa igihe umuntu akeneye uburyo bworoshye bwo kuvura amagufa. Muganga wawe azatekereza uko ubuzima bwawe buhagaze, harimo amateka yawe y'ubuvuzi n'uburyo wihanganira imiti, kugirango amenye uburyo bwiza kuri wowe.

Ibibazo Bikunze Kubazwa Kuri Etidronate

Ese Etidronate irakwiriye ku bantu barwaye indwara z'umutima?

Etidronate muri rusange irakwiriye ku bantu barwaye indwara z'umutima, kuko ntigira ingaruka zigororotse ku mikorere y'umutima. Ariko, ugomba buri gihe kubwira muganga wawe ibijyanye n'uburwayi bwawe bwose, harimo ibibazo by'umutima, mbere yo gutangira umuti mushya uwo ariwo wose.

Abantu bamwe barwaye indwara z'umutima bafata imiti ishobora kugirana imikoranire na etidronate cyangwa ikagira ingaruka ku buryo ikoreshwa neza. Muganga wawe ashobora gusuzuma imiti yawe yose kugirango yemeze ko ikora neza kandi agahindura igihe cyo kuyifata niba bibaye ngombwa.

Nkwiriye gukora iki niba nanyweye etidronate nyinshi bitunguranye?

Niba unyweye etidronate nyinshi kuruta uko byategetswe, ntugahagarike umutima, ariko ukore icyo ugomba gukora vuba. Nywa ikirahure cyuzuye cy'amata cyangwa ufate ibinini bya kalisiyumu niba ubyifitiye, kuko kalisiyumu ishobora gufasha gukuraho imiti yarenze urugero.

Vugana na muganga wawe cyangwa ikigo gishinzwe kugenzura uburozi ako kanya, cyane cyane niba wanyweye nyinshi cyane kuruta urugero rwawe rusanzwe. Bashobora kukugira inama y'icyo ugomba kwitaho niba ukeneye ubufasha bwihuse bw'ubuvuzi.

Ibimenyetso byo kunywa nyinshi bishobora kuba isesemi ikabije, kuruka, kuribwa mu nda, cyangwa kubabara imitsi. Ntugerageze kwivugisha niba utabitegetswe na umuganga.

Nkwiriye gukora iki niba nirengagije gufata urugero rwa etidronate?

Niba wibagiwe gufata urugero rwa etidronate, ifate ako kanya wibukiye, ariko gusa niba ushobora gukurikiza amategeko akwiye yo kuyifata. Ibi bivuze kuyifata ku gifu cyambaye ubusa kandi ushobore guhagarara neza byibuze iminota 30 nyuma yo kuyifata.

Niba igihe cyo gufata urundi rugero ruri hafi, reka urugero rwasibye ukomeze gahunda yawe isanzwe. Ntukigere ufata imiti ibiri icyarimwe kugira ngo usimbure urugero rwasibye, kuko ibyo bishobora kongera ibyago byo kugira ingaruka ziterwa n'imiti.

Kusiba urugero rimwe na rimwe ntibizagira ingaruka zikomeye ku buvuzi bwawe, ariko gerageza gukomeza gahunda yawe isanzwe uko bishoboka kose kugira ngo ugere ku ngaruka nziza.

Ni ryari nshobora kureka gufata Etidronate?

Ntuzigere ureka gufata etidronate utabanje kuvugana na muganga wawe, kabone n'iyo wumva umeze neza. Indwara z'amagufa akenshi zisaba kuvurwa igihe kirekire, kandi kureka imiti kare kare bishobora gutuma uburwayi bwawe burushaho kuba bubi.

Muganga wawe azagenzura buri gihe uko urimo utera imbere ukoresheje ibizamini by'amaraso ndetse n'ibishobora kuba byerekana ubucucike bw'amagufa. Bazakumenyesha igihe byemewe guhagarika cyangwa guhagarika gato ubuvuzi bitewe n'uko amagufa yawe asubiza.

Abantu bamwe bashobora guhagarika nyuma yo kurangiza uburyo bwihariye bwo kuvura, mu gihe abandi bashobora gukenera kuvurwa buri gihe bafite akaruhuko hagati. Uko ubuzima bwawe bwite buteye ni byo bizagena uburyo bwiza kuri wowe.

Nshobora gufata imiti yongera kalisiyumu nkanjye mfata Etidronate?

Yego, imiti yongera kalisiyumu akenshi irasabwa mugihe ufata etidronate, ariko igihe ni ingenzi. Ugomba gutandukanya urugero rwawe rwa etidronate n'imiti yongera kalisiyumu byibuze amasaha 2 kugira ngo wirinde kubangamira imikorere yayo.

Abaganga benshi basaba gufata imiti yongera kalisiyumu nimugoroba niba ufata etidronate mu gitondo. Ibi bituma imiti yombi ikora neza itabangamiye.

Muganga wawe ashobora kandi gusaba imiti yongera vitamine D kugira ngo ifashe umubiri wawe gukoresha kalisiyumu neza. Buri gihe ukurikize inama zabo zihariye zijyanye n'imiti yo gufata n'igihe cyo kuyifata.