Ni iki cyitwa aside ya fenofibric: Ibyo ikoreshwa, urugero rwo gufata, ingaruka zayo n'ibindi

Aside ya fenofibric ni umuti wandikirwa na muganga ufasha kugabanya urugero rwo hejuru rw'ibinure mu maraso yawe, cyane cyane triglycerides na cholesterol. Uyu muti ubarizwa mu itsinda ry'imiti yitwa fibrates, ikora ifasha umubiri wawe gutunganya ibinure neza. Muganga wawe ashobora kukwandikira uyu muti igihe imirire n'imyitozo gusa bidahagije ngo bigabanye urugero rwa cholesterol na triglycerides mu buryo buzima.

Aside ya fenofibric ni iki?

Aside ya fenofibric ni uburyo bukora bwa fenofibrate, umuti wagenewe kuvura urugero rwo hejuru rwa cholesterol na triglycerides. Tekereza nk'umufasha wigisha umwijima wawe gutunganya ibinure neza. Bitandukanye n'indi miti imwe ya cholesterol, aside ya fenofibric ifite akamaro cyane mu kugabanya triglycerides, ubwoko bw'ibinure bushobora kwiyongera mu maraso yawe iyo urya kalori nyinshi ugereranije n'uko umubiri wawe ukeneye.

Uyu muti uza mu buryo bwa capsule itinda gusenyuka ufata unywa. Uburyo bwo gutinda gusenyuka bisobanura ko umuti wagenewe gusenyuka buhoro buhoro mu gihe cyo gukora ibyo ushaka mu mubiri wawe, uha umubiri wawe urugero rwo guhoraho umunsi wose.

Aside ya fenofibric ikoreshwa mu iki?

Aside ya fenofibric ivura urugero rwo hejuru rwa cholesterol na triglycerides mu maraso yawe, ibi bikaba bishobora kongera ibyago byo kurwara umutima na stroke. Muganga wawe akenshi azakwandikira uyu muti iyo urugero rw'ibinure mu maraso yawe rukomeje kuba rwinshi nubwo ukurikiza imirire y'umutima kandi ukora imyitozo ngororamubiri buri gihe.

Dore indwara nyamukuru aside ya fenofibric ifasha kuvura:

• Triglycerides nyinshi (hypertriglyceridemia)
• Cholesterol nyinshi ya LDL (cholesterol "mbi")
• Cholesterol nkeya ya HDL (cholesterol "nziza")
• Dyslipidemia ivanze (iyo urugero rwinshi rw'ibinure mu maraso rudasanzwe)

Muganga wawe ashobora no kukwandikira umuti wa fenofibric acid niba ufite indwara yitwa familial hypercholesterolemia, aho cholesterol nyinshi ikunda kuboneka mu muryango wawe. Uyu muti ukora neza nk'igice cy'uburyo bwuzuye burimo kurya neza, gukora imyitozo ngororamubiri buri gihe, no kugenzura ibiro.

Fenofibric acid ikora ite?

Fenofibric acid ikora ikoresha ibyuma byihariye mu mwijima wawe byitwa PPAR-alpha receptors. Ibi byuma bikora nk'ibishushanyo bibwira umwijima wawe gusenya amavuta neza kandi bikagabanya amavuta yangiza ashobora kuziba imitsi yawe.

Uyu muti ufatwa nk'ukomeye ku rugero ruciriritse ugereranije n'indi miti igabanya cholesterol. Mugihe statins akunda kuba uburyo bwa mbere bwo kugabanya LDL cholesterol, fenofibric acid ifasha cyane mu kugabanya triglycerides ku kigero cya 30-50% ku bantu benshi. Irashobora kandi gufasha kuzamura urwego rwawe rwa HDL cholesterol, ibyo bikaba bifitiye umutima wawe akamaro.

Umuti ufata igihe kugirango werekane ingaruka zawo zose. Ushobora gutangira kubona impinduka mu rwego rw'amavuta yo mu maraso yawe mu byumweru 2-4, ariko bishobora gufata amezi 3 kugirango ubone akamaro kenshi.

Nkwiriye gufata fenofibric acid nte?

Fata fenofibric acid nkuko muganga wawe abikwandikiye, akenshi rimwe ku munsi hamwe n'ibiryo. Kuyifata hamwe n'ifunguro bifasha umubiri wawe gukurura umuti neza kandi bigabanya amahirwe yo kurwara mu gifu.

Ubu ni uburyo bwo gufata umuti wawe neza:

1. Mimina ikinini cyose hamwe n'ikirahure cy'amazi yuzuye
2. Ntukamenagure, ntukayigunye, cyangwa ngo ufungure ibinini byihariye
3. Fata ku gihe kimwe buri munsi kugirango wibuke
4. Urashobora kuyifata hamwe n'ifunguro iryo ariryo ryose, ariko kugira amavuta make mu ifunguro bifasha umubiri kuyakira

Ntabwo bisaba gukurikiza ibyo kurya byihariye, ariko kurya amavuta make meza hamwe n'urugero rwawe rw'umuti birashobora gufasha umuti gukora neza. Agace gato k'ibinyomoro, amavuta ya elayo, cyangwa avoka hamwe n'ifunguro ryawe ni byiza.

Nzamara Mfite Fenofibric Acid Ryari?

Abantu benshi bakeneye gufata fenofibric acid igihe kirekire kugira ngo bagumane urugero rwiza rwa cholesterol na triglyceride. Uyu muti ntukiza cholesterol nyinshi ariko ufasha kuyicunga, kimwe n'uko imiti igabanya umuvuduko w'amaraso ikora ku bantu bafite umuvuduko ukabije w'amaraso.

Muganga wawe azakurikiza uko urimo utera imbere akoresheje ibizamini by'amaraso buri gihe, akenshi buri mezi 3-6 mu ntangiriro, hanyuma bikorwe kenshi iyo urugero rwawe rumaze kuringanira. Igihe cyo kuvurwa giterwa n'uko umuti ukora neza kuri wowe niba hari ingaruka zikubaho.

Abantu bamwe bashobora kugabanya urugero rw'umuti bafata cyangwa bakawuhagarika niba bakoze impinduka zikomeye mu mibereho yabo, bagabanya ibiro, cyangwa niba uburwayi bwabo bwateye imbere. Ariko, ntuzigere uhagarika gufata fenofibric acid utabanje kubaza muganga wawe, kuko urugero rwa cholesterol yawe rushobora gusubira ku rugero rwayo rwo hejuru rwa mbere.

Ni Izihe Ngaruka Ziterwa na Fenofibric Acid?

Abantu benshi bafata fenofibric acid neza, ariko nk'imiti yose, ishobora gutera ingaruka. Inkuru nziza ni uko ingaruka zikomeye zitaba kenshi, kandi abantu benshi ntibagira ingaruka na gato.

Ingaruka zisanzwe zibaho ku bantu bamwe zirimo:

• Kubabara mu nda cyangwa kutumva neza
• Kuruka cyangwa kumva uruka
• Umutwe
• Kubabara mu mugongo
• Ibimenyetso bisa n'ibikonjo

Izi ngaruka zoroheje akenshi zitungana uko umubiri wawe wimenyereza umuti, akenshi mu byumweru bike umaze gutangira kuvurwa.

Ingaruka zitaba kenshi ariko zikomeye zisaba ubufasha bwihuse bw'abaganga:

• Kubabara imitsi, kunanirwa, cyangwa kumva itameze neza
• Inkari zifite ibara ryijimye
• Uruhu cyangwa amaso y'umuhondo (jaundice)
• Kubabara cyane mu nda
• Kunanirwa cyangwa kunanuka bidasanzwe

Ibi bimenyetso bishobora kwerekana ibibazo by'imitsi cyangwa ibibazo by'umwijima, bidasanzwe ariko bisaba isuzuma ryihuse ry'abaganga. Vugana na muganga wawe ako kanya niba ubonye kimwe muri ibi bimenyetso.

Ninde Utagomba Gufata Asidi ya Fenofibric?

Asidi ya Fenofibric ntibitewe n'umutekano kuri buri wese, kandi muganga wawe azasuzuma neza amateka yawe mbere yo kuyandika. Ibyiciro bimwe na bimwe bituma uyu muti utabereye cyangwa bisaba gukurikiranwa byihariye.

Ntugomba gufata asidi ya fenofibric niba ufite:

• Indwara ikomeye y'impyiko
• Indwara y'umwijima ikora
• Indwara y'urwagashya
• Amateka ya pankreatite
• Allergie izwi kuri asidi ya fenofibric cyangwa fenofibrate

Muganga wawe azitonda kandi mu kwandika uyu muti niba ufata indi miti imwe na imwe, cyane cyane imiti ituma amaraso atavura nka warfarin, kuko asidi ya fenofibric ishobora kongera ibyago byo kuva amaraso.

Niba utwite, uteganya gutwita, cyangwa wonka, biganireho na muganga wawe. Umutekano wa asidi ya fenofibric mugihe cyo gutwita no konka nturasobanuka neza, bityo muganga wawe azagereranya inyungu n'ibyago bishoboka.

Amazina y'ubwoko bwa Asidi ya Fenofibric

Asidi ya Fenofibric iboneka munsi y'izina ry'ubwoko rya Fibricor muri Leta Zunze Ubumwe z'Amerika. Iri nicyo gihangange gikoreshwa cyane, nubwo ubwoko bwa rusange bwa asidi ya fenofibric buboneka kandi.

Ushobora kandi kumva ibijyanye n'imiti ifitanye isano nka Tricor cyangwa Antara, ariko ibi birimo fenofibrate aho kuba asidi ya fenofibric. Mugihe bakora kimwe, asidi ya fenofibric nicyo kintu gikora kitasaba guhindurwa mumubiri wawe, ibyo bishobora kubigira byoroshye mubikorwa byayo.

Buri gihe koresha ubwoko cyangwa ubwoko rusange muganga wawe yanditse, kandi ntukimure hagati yuburyo butandukanye utabanje kubaza umuganga wawe.

Uburyo bwo gusimbuza Asidi ya Fenofibric

Niba asidi ya fenofibric itagukundiye neza cyangwa itera ingaruka ziterwa n'imiti, hari ubundi buryo butandukanye bushobora gufasha kugenzura cholesterol ndende na triglycerides. Muganga wawe azahitamo uburyo bwiza bushingiye ku gipimo cyawe cyihariye cy'ibinyamutungo byo mu maraso n'ubuzima.

Ibindi byongerera imiti birimo:

• Gemfibrozil (Lopid)
• Fenofibrate (Tricor, Antara)
• Bezafibrate (ntaboneka muri Amerika)

Uburyo butari ubwa fibrate bwo gucunga cholesterol burimo statins nka atorvastatin (Lipitor) cyangwa simvastatin (Zocor), akenshi zikora neza mu kugabanya LDL cholesterol. Kubantu bafite triglycerides nyinshi cyane, muganga wawe ashobora gutekereza ku mavuta ya omega-3 fatty acids yandikiwe nka icosapent ethyl (Vascepa).

Rimwe na rimwe, guhuza ubwoko butandukanye bwimiti ya cholesterol bikora neza kurusha gukoresha imwe gusa. Muganga wawe azahindura gahunda yawe yo kuvura ukurikije ibyo ukeneye n'uburyo witwara ku buvuzi.

Ese Fenofibric Acid iruta Gemfibrozil?

Bombi fenofibric acid na gemfibrozil ni imiti ya fibrate ikora neza, ariko bafite itandukaniro rikomeye rishobora gutuma imwe ikwemerera kurusha iyindi.

Fenofibric acid irashobora gukundwa kuko ifite imiti mike ihura, cyane cyane hamwe na statin. Niba ukeneye bombi fibrate na statin, fenofibric acid muri rusange niyo nziza. Ifatwa kandi rimwe ku munsi, abantu benshi babona ko byoroshye kurusha gemfibrozil ifatwa kabiri ku munsi.

Gemfibrozil imaze igihe kinini kandi ifite ubushakashatsi bwinshi bwerekana akamaro kayo mu gukumira indwara z'umutima. Ariko, ihura nindi miti myinshi kandi irashobora kongera cyane ibibazo by'imitsi iyo ihujwe na statins.

Muganga wawe azatekereza ku yindi miti ufata, imikorere y'impyiko, n'ibyo ukunda mugihe uhitamo hagati yibi bintu. Nta muti n'umwe ushobora kuba "mwiza" - biterwa n'imibereho yawe bwite n'ubuzima bwawe.

Ibikunze Kubazwa Kuri Fenofibric Acid

Ese Fenofibric Acid irakwiriye abarwayi ba diyabete?

Yego, fenofibric acid muri rusange irakwiriye abantu barwaye diyabete ndetse ishobora no gutanga izindi nyungu. Abantu barwaye diyabete akenshi baba bafite triglycerides nyinshi na HDL cholesterol nkeya, ibyo fenofibric acid ishobora gufasha kunoza.

Ubushakashatsi bumwe buvuga ko imiti nka fenofibric acid ishobora gufasha kugabanya ibibazo bimwe na bimwe bijyanye na diyabete, cyane cyane indwara ya diyabete y'amaso (ibibazo by'amaso). Ariko, uzakenera gukurikiranwa buri gihe ku rugero rw'isukari mu maraso yawe n'imikorere y'impyiko, kuko diyabete ishobora kugira ingaruka ku buryo umubiri wawe ukoresha uyu muti.

Nkwiriye gukora iki niba nanyweye fenofibric acid nyinshi ku buryo butunganye?

Niba unyweye fenofibric acid nyinshi ku buryo butunganye, vugana n'umuganga wawe cyangwa ikigo gishinzwe kugenzura uburozi ako kanya. Kunywa nyinshi bishobora kongera ibyago byo kugira ingaruka zikomeye, cyane cyane ibibazo by'imitsi n'ibibazo by'umwijima.

Ntugerageze gusimbura doze yinyongera usiba doze yawe ikurikira. Ahubwo, garuka ku gahunda yawe isanzwe yo kunywa imiti kandi umenyeshe umuganga wawe icyabaye. Bashobora kwifuza kugukurikirana cyane cyangwa guhindura gahunda yawe yo kuvurwa.

Nkwiriye gukora iki niba nirengagije doze ya fenofibric acid?

Niba wibagiwe doze ya fenofibric acid, yinywere ako kanya wibuka, ariko niba ari umunsi umwe. Niba igihe cyo gufata doze yawe ikurikira cyageze cyangwa hafi yacyo, siba doze wibagiwe ukomeze gahunda yawe isanzwe.

Ntuzigere ufata doze ebyiri icyarimwe kugira ngo usimbure doze wibagiwe, kuko ibi bishobora kongera ibyago byo kugira ingaruka zikomeye. Niba ukunda kwibagirwa doze, tekereza gushyiraho umwanya wo kwibutswa kuri terefone cyangwa gufata umuti wawe icyarimwe n'ibindi bikorwa bya buri munsi nka saftani cyangwa kumesa amenyo yawe.

Nshobora kureka kunywa fenofibric acid ryari?

Ugomba kureka kunywa fenofibric acid gusa ukurikije ubuyobozi bw'umuganga wawe. Abantu benshi bakeneye gukomeza kunywa uyu muti igihe kirekire kugira ngo bagumane urugero rwiza rwa kolesteroli na triglyceride.

Muganga wawe ashobora gutekereza guhagarika cyangwa kugabanya urugero rw'umuti niba wahinduye cyane imibereho yawe, wagabanyije ibiro, cyangwa niba urugero rw'ibinure byo mu maraso yawe rwaragumye mu rugero rwiza mu gihe kirekire. Ariko, guhagarika umuti mubisanzwe bituma urugero rwa kolesteroli na trigliseride bisubira ku rugero rwo hejuru rwari ruriho mbere mu byumweru bike.

Nshobora kunywa inzoga nkanwa Fenofibric Acid?

Ni byiza kugabanya kunywa inzoga nkanwa fenofibric acid, kuko inzoga n'uyu muti byombi bishobora kugira ingaruka ku mwijima wawe. Gukoresha inzoga mu rugero ruringaniye (icyo kunywa kimwe ku munsi ku bagore, bibiri ku bagabo) mubisanzwe byemewe, ariko kunywa inzoga nyinshi bishobora kongera ibyago byo kurwara umwijima na pankreatite.

Inzoga kandi ishobora kuzamura urugero rwa trigliseride, ibyo bikaba bikora ibinyuranye n'icyo umuti ugerageza gukora. Niba ukunda ibinyobwa bisembuye, ganira ukuri ku ngeso zawe zo kunywa inzoga na muganga wawe kugira ngo batange ubujyanama bwihariye ku miterere yawe.