Icyo Fludeoxyglucose F-18 ari cyo: Ibyo ikoreshwa, urugero rwo kuyifata, ingaruka zayo n'ibindi

Fludeoxyglucose F-18 ni isukari idasanzwe ifite imirasire ifasha abaganga kureba uko umubiri wawe ukoresha imbaraga. Yinjizwa mu muyoboro w'amaraso yawe ikagenda mu maraso yawe ikereka ahantu uturemangingo dukora cyane kurusha uko bisanzwe, ibyo bikaba byafasha kumenya kanseri, ibibazo by'umutima, cyangwa indwara zo mu bwonko.

Uyu muti ukoreshwa mu kugaragaza ishusho y'ubuzima bw'umuntu ukora nk'umuganga w'indwara, ukerekana uturemangingo dukora cyane ku byuma byihariye bita PET scans. Tekereza nk'ikintu cy'umutekano, gishobora gukoreshwa igihe gito gifasha ikipe yawe y'abaganga kubona ishusho isobanutse y'ibiri kuba imbere mu mubiri wawe.

Fludeoxyglucose F-18 ni iki?

Fludeoxyglucose F-18 ni isukari ifite imirasire (isukari) umubiri wawe ukoresha nk'isukari isanzwe. Itandukaniro rikomeye ni uko ikubiyemo fluorine-18 nto, ituma igaragara ku byuma bigaragaza ishusho y'ubuzima bw'umuntu.

Uturemangingo twawe dukoresha iyi sukari yahinduwe iyo dukeneye imbaraga. Uturemangingo twa kanseri, imitsi yabyimbye, n'uturere tw'ubwonko dukora cyane dukunda kuyikoresha cyane kuko dukora cyane kurusha uturemangingo dusanzwe. Ibi bituma habaho ahantu hasa neza ku ishusho bifasha abaganga kumenya ahantu hari ibibazo.

Igice gifite imirasire gisa n'ikiteye ubwoba, ariko mu by'ukuri ni umutekano mwinshi. Umubare w'imirasire ni muto kandi usohoka mu mubiri wawe mu buryo busanzwe mu masaha make ukoresheje inkari zawe n'umwuka wawe.

Fludeoxyglucose F-18 ikoreshwa mu iki?

Abaganga bakoresha uyu muti ugaragaza ishusho y'ubuzima bw'umuntu cyane cyane mu kumenya no gukurikirana kanseri mu mubiri wawe. Bifasha cyane mu kubona ibibyimba bishobora kuba bito cyane ku buryo bitagaragara ku byuma bisanzwe bya CT cyangwa X-ray.

Usibye kumenya kanseri, bifasha gusuzuma ibibazo byinshi by'ingenzi bigira ingaruka ku buzima bwawe bwa buri munsi:

• Indwara z'umutima - kugaragaza ibice by'imitsi y'umutima wawe bibona amaraso ahagije
• Indwara zo mu bwonko nka Alzheimer, epilepsi, cyangwa ubumuga bwo mu mutwe
• Udukoko tworoshye kubona n'izindi tests
• Ibyiciro by'uburwayi bwandura bugira ingaruka ku ngingo cyangwa imitsi
• Kugenzura uburyo imiti ivura kanseri ikora neza

Muganga wawe ashobora kandi gushimangira iri suzuma niba ufite ibimenyetso bitasobanuwe bigaragaza uburwayi bukomeye. Bimeze nk'ukugira ikarita y'ubuzima yuzuye yerekana imiterere y'ibikorwa by'umubiri wawe.

Fludeoxyglucose F-18 ikora ite?

Ibi bifatwa nk'igikoresho cyoroshye ariko gikomeye cyo gupima gikora mu kwigana imikorere y'isukari y'umubiri wawe. Iyo yatewe, igenda mu maraso yawe ikinjira mu turemangingo dukeneye ingufu.

Iyi nzira ibaho mu ntambwe eshatu zoroheje. Mbere na mbere, uturemangingo twawe twinjiza isukari ifite radioactivite nk'uko byagenda kuri glucose isanzwe. Hanyuma, fluorine-18 itanga utuntu duto twitwa positrons scanner ya PET ishobora kumenya. Hanyuma, scanner ikora amashusho arambuye yerekana aho isukari yateraniye mu mubiri wawe.

Ahantu hakiri isukari nyinshi bigaragara cyane kuri scan. Ururugero, uturemangingo twa kanseri, akenshi dukoresha isukari nyinshi kuruta uturemangingo dusanzwe, bityo bigaragara nk'ahantu hatukura. Ibi bifasha abaganga gutandukanya hagati y'imitsi y'ubuzima bwiza n'idahwitse hamwe n'ubunyamwuga butangaje.

Nkwiriye gufata nte Fludeoxyglucose F-18?

Mu by'ukuri ntabwo "ufata" uyu muti nk'ipilule cyangwa umuti w'amazi. Ahubwo, umuhanga mu buvuzi bwa nikleyeri watojwe azawutera mu urugingo rwawe rwo mu kuboko rwawe anyuze mu rusinga ruto.

Kwitegura guterwa urukingo bisaba intambwe zimwe zihariye kugirango zishobore gutanga umusaruro mwiza. Uzakenera kwiyiriza byibuze amasaha 4-6 mbere yo guhura na muganga, unywa amazi gusa muri iki gihe. Ibi bifasha umubiri wawe kwinjiza isukari ifite radioactivite neza.

Ibi nibyo byitezwe ku munsi wo gusuzumwa:

1. Uze wambaye imyenda yoroshye, itagufashe cyane kandi idafite ibyuma
2. Kura impeta, amenyo y'ubwoko bwose, cyangwa ikintu icyo aricyo cyose kirimo icyuma
3. Wakira urushinge wicaye neza mu ntebe yoroheje
4. Uruhuke iminota 45-60 kugira ngo umuti ukwirakwire mu mubiri wawe
5. Kora isesengura rya PET, rifata iminota 20-30

Igihe cyo gutegereza nyuma yo guterwa urushinge ni ingenzi kuko bituma isukari ifite imirasire igera mu bice byose by'umubiri wawe. Muri iki gihe, uzasabwa kuguma utuje kandi wirinde gukora imyitozo ngororamubiri kugira ngo umuti utinjira mu misitsi.

Nzagenda mfata Fludeoxyglucose F-18 igihe kingana iki?

Uyu si umuti ufata kenshi nk'ibindi binini bya buri munsi. Uhabwa urushinge rumwe kuri buri sesengura rya PET muganga wawe ategeka, rishobora kuba rimwe, kabiri, cyangwa inshuro nyinshi bitewe n'uburwayi bwawe bwihariye.

Isukari ifite imirasire iva mu mubiri wawe mu buryo busanzwe mu masaha 24 nyuma yo guterwa urushinge. Byinshi muri byo biva mu nkari zawe mu masaha 6 ya mbere, n'ibice bito bivanwa mu mwuka wawe no mu myanda yo mu mara.

Niba ukeneye gukora ibindi bisesengura kugira ngo ukurikirane uko imiti ikora cyangwa urebe niba kanseri yongeye kugaruka, ibi bikunze gukorwa nyuma y'ibyumweru cyangwa amezi. Muganga wawe azagena igihe gikwiye bitewe n'uburwayi bwawe bwihariye n'indwara irimo gukurikiranwa.

Ni izihe ngaruka ziterwa na Fludeoxyglucose F-18?

Abantu benshi ntibagira ingaruka na zimwe na zimwe ziterwa n'uyu muti ukoreshwa mu isesengura. Uko guterwa urushinge bimeze bisa no gukuramo amaraso cyangwa gushyiramo urushinge, hamwe n'ububabare bucye gusa ahaterwa urushinge.

Ubusanzwe, iyo bibayeho, ingaruka zikunze kuba nto cyane kandi ntizimara igihe kirekire:

• Urubavu ruto cyangwa ibibazo aho urushinge rwashyizwe
• Kugira umunaniro muke mu masaha nyuma yo gukora isesengura
• Uburyohe bw'icyuma bw'agateganyo mu kanwa kawe
• Kumva ushyushye cyangwa uhindutse umutuku gato nyuma yo guterwa urushinge

Ibi bimenyetso akenshi bikira mu masaha make hatagize uburyo na bumwe buvura. Kunywa amazi menshi bifasha gukuramo ibikoresho bya radiyoactive mu mubiri wawe vuba.

Uburwayi bukomeye bwo kwivumbura ku bintu bitandukanye ni gake cyane ariko bushobora kwigaragaza mu guhumeka bigoranye, uruhu rururuka cyane, cyangwa kubyimba mu maso no mu muhogo. Niba ubonye kimwe muri ibi bimenyetso, gisha ubufasha bwihuse bw'abaganga. Itsinda ry'abaganga rikora isesengura ryawe ryatojwe guhangana n'ibi bibazo nibiramuka bibayeho.

Ninde utagomba gufata Fludeoxyglucose F-18?

Abantu bamwe na bamwe bakeneye kwitabwaho by'umwihariko cyangwa bagomba kwirinda iki gikoresho cyo gupima rwose. Abagore batwite ntibagomba guhabwa iyi nshinge keretse inyungu z'ubuvuzi zigaragaza neza ko zirenze ibyago bishobora kuba ku mwana ukura.

Muganga wawe azasuzuma neza uko umeze niba uri mu cyiciro icyo aricyo cyose muri ibi bikurikira:

• Abagore batwite cyangwa bashobora kuba batwite
• Ababyeyi bonka (ushobora gukenera kuvoma no kumenagura amata y'ibere mu masaha 24)
• Abantu barwaye diyabete itagenzurwa cyangwa bafite isukari yo mu maraso iri hejuru cyane
• Abana bari munsi y'imyaka 18 (bisaba kwitondera imiti)
• Abantu bafite ibibazo bikomeye by'impyiko batabasha gukuramo neza icyo gikoresho

Niba urwaye diyabete, urugero rwawe rw'isukari mu maraso rugomba kuba ruri ku rugero rwiza mbere yo gupimwa. Urugero rwa glucose ruri hejuru rushobora kubangamira imikorere y'isukari ya radiyoactive, bishobora kugira ingaruka ku kuri kw'ibisubizo byawe.

Abantu bafite claustrophobia bashobora gusanga uburyo bwo gupima bugoye, ariko ibi bifitanye isano na PET scanner ubwayo aho kuba inshinge. Itsinda ryawe ry'abaganga rishobora gutanga uburyo bwo kuruhuka cyangwa imiti yoroheje niba bikenewe.

Amazina y'ubwoko bwa Fludeoxyglucose F-18

Iki gikoresho cyo gupima kiboneka mu mazina menshi y'ubwoko, nubwo icyo gikoresho gikora kigumaho kimwe hatitawe ku mukora. Izina risanzwe rikoreshwa ni Fluorodeoxyglucose F-18, risa cyane n'izina rusange.

Ushobora kandi kumva bivugwa nka FDG, F-18 FDG, cyangwa gusa "tracer" n'ikipe yawe y'abaganga. Ibikorwa bimwe na bimwe bikoresha amazina yihariye y'ubwoko nka Fludeoxyglucose F-18 Injection cyangwa izindi nyito zidasanzwe z'abakora.

Ikintu cy'ingenzi cyo kwibuka ni uko aya mazina yose yerekeza ku kintu kimwe cya glucose gifite radio. Ubuziranenge n'imikorere bikomeza guhuza mu bwoko butandukanye kuko bagomba guhura n'amabwiriza akomeye ya FDA y'umutekano n'isuku.

Uburyo bwo gusimbuza Fludeoxyglucose F-18

Uburyo butandukanye bwo gushushanya bushobora gutanga amakuru asa n'aya yo gupima, nubwo buri kimwe gifite imbaraga zacyo n'intege nke. CT scans hamwe na contrast dye irashobora kwerekana imiterere y'umubiri irambuye ariko ntigaragaza ibikorwa bya selile nkuko PET scans zibikora.

MRI scans irusha abandi kwerekana ibisobanuro by'imitsi yoroshye kandi rimwe na rimwe irashobora kumenya kanseri, ariko ntizikora neza mu kubona ibibyimba bito cyangwa gukurikirana uburyo bwo kuvura. Gupima amagufa hakoreshejwe ibintu bitandukanye bifite radio bishobora kumenya kanseri yagiye mu magufa ariko ntibikora neza nka PET scans.

Izindi tracer zifite radio usibye F-18 FDG zirimo:

• Ibintu bya Gallium-68 kubwoko bwihariye bwa kanseri
• Technetium-99m yo gushushanya umutima n'amagufa
• Iodine-123 yo kwiga imikorere ya tiroyide
• Carbon-11 tracers yo gushushanya ubwonko mu bushakashatsi

Muganga wawe azahitamo uburyo bwiza bwo gushushanya hashingiye ku bimenyetso byawe byihariye, amateka yawe y'ubuvuzi, n'amakuru akenewe kugirango uyobore uburyo bwawe bwo kuvura. Rimwe na rimwe uburyo bwinshi bwo gushushanya bukoreshwa hamwe kugirango tubone ishusho yuzuye.

Ese Fludeoxyglucose F-18 iruta CT Scans?

Uburyo bwombi bwo gushushanya bufite inyungu zidasanzwe zibagira agaciro kubibazo bitandukanye by'ubuvuzi. PET scans hamwe na F-18 FDG irusha abandi kumenya ibikorwa bya kanseri no kwerekana uburyo selile zikora, mugihe CT scans itanga amashusho arambuye y'imiterere y'umubiri n'imyubakire.

Ibyuma bya PET birusha izindi mu kugaragaza kanseri yongeye kugaruka, gusuzuma uko imiti yafashije, no gushaka kanseri yaguye ahantu hatari hategerejwe. Akenshi bishobora kugaragaza selile za kanseri zikora mbere yuko ibibyimba biba binini bihagije ngo bigaragare ku byuma bya CT.

Ibyuma bya CT, ariko, birusha izindi mu:

• Kugaragaza neza ubunini n'ahantu ibibyimba biherereye
• Kugaragaza ubwoko runaka bw'ibibazo by'umwijima
• Gusuzuma ibikomere cyangwa amagufa yavunitse
• Kuyobora biopsies cyangwa imikorere yo kubaga
• Ibihe by'ubutabazi bisaba ibisubizo byihuse

Ibikorwa byinshi by'ubuvuzi ubu bitanga ibyuma bya PET-CT bihurijweho bitanga amakuru yombi akora n'ayubaka mu gihe kimwe. Ubu buryo buhurijweho akenshi butanga abaganga ishusho yuzuye y'uburwayi bwawe.

Guhitamo hagati y'ubu buryo bwo gupima biterwa n'ikibazo cyawe cy'ubuvuzi. Muganga wawe azagusaba uburyo bushobora gutanga amakuru akenewe kugira ngo afashe kwita ku buzima bwawe neza.

Ibikunze Kubazwa ku bijyanye na Fludeoxyglucose F-18

Q1. Ese Fludeoxyglucose F-18 iratekanye ku bantu barwaye diyabete?

Yego, abantu barwaye diyabete bashobora kwakira ubu buryo bwo gupima batekanye, ariko kugenzura isukari mu maraso ni ngombwa kugira ngo habeho ibisubizo by'ukuri. Urwego rwawe rwa glucose rugomba kuba ruri munsi ya 200 mg/dL, kandi byaba byiza ruri hafi y'urwego rusanzwe mbere yo guterwa urushinge.

Isukari nyinshi mu maraso ishobora guhangana na glucose ya radiyo kugira ngo ifatwe na selile zawe, bishobora gutuma kanseri cyangwa ahandi hantu hatari hasanzwe bigorana kubona. Itsinda ryawe ry'abaganga rizasuzuma isukari yawe mu maraso mbere y'igikorwa kandi rishobora kongera guteganya niba urwego ruri hejuru cyane.

Niba ufata imiti ya diyabete, muganga wawe ashobora guhindura gahunda yawe yo gufata imiti ku munsi wo gupimwa. Komeza gufata imiti yawe nkuko byategetswe keretse niba byategetswe mu buryo bwihariye n'umuganga wawe.

Q2. Nkwiriye gukora iki niba mbonye Fludeoxyglucose F-18 nyinshi mu buryo butunganye?

Gukoresha imiti y'uburozi mu buryo butunganye ni gake cyane kuko abantu b'inzobere mu buvuzi bwa za nukleyeri babara kandi bapima buri doze neza. Ariko, niba ufite impungenge zo kwakira byinshi, vugana n'ikipe yawe y'abaganga ako kanya kugira ngo bagufashe.

Ibimenyetso byo kwakira ibintu byinshi bifite imirasire ntibisanzwe ariko bishobora kurimo isesemi, kuruka, cyangwa umunaniro udasanzwe. Ibi bimenyetso bishobora kandi guterwa n'izindi mpamvu, bityo isuzuma ry'ubuvuzi ni ingenzi kugira ngo hamenyekane icyateye ikibazo.

Intambwe y'ingenzi ni ukunywa amazi menshi kugira ngo afashe gukuramo ibintu byinshi bifite imirasire mu mubiri wawe binyuze mu kunyara. Ikipe yawe y'abaganga ishobora kandi kugusaba izindi ngamba z'umutekano zishingiye ku miterere yawe yihariye n'ubwinshi bw'ibintu byinshi byakiriwe.

Q3. Nkwiriye gukora iki niba ntasibye inshinge yanjye ya Fludeoxyglucose F-18?

Vugana n'ikigo cy'ubuvuzi vuba bishoboka kugira ngo usubize gahunda yawe. Bitandukanye n'imiti ikoreshwa buri munsi, kutitabira iyi nshinge ntibitera ibyago by'ubuzima byihuse, ariko bitinda amakuru y'ingenzi yo gusuzuma.

Ikigo gishinzwe gushushanya kizakorana nawe kugira ngo kibone gahunda ikurikira iboneye. Bazi ko ubuzima bugenda kandi ibibazo byihutirwa bivuka, bityo akenshi bafasha cyane mu gusubiza gahunda.

Uko imiterere y'ubuvuzi imeze irihutirwa kurusha iyindi, bityo menyesha ikipe ishinzwe gutegura gahunda niba muganga wawe yarashimangiye akamaro ko kurangiza isesengura vuba. Bashobora kugufasha vuba cyangwa bagatanga ibitekerezo by'uburyo bwakoreshwa.

Q4. Nshobora guhagarika ryari guhangayika ku bijyanye n'imirasire ya Fludeoxyglucose F-18?

Ibintu bifite imirasire ntibishobora kugaragara mu mubiri wawe mu masaha 24 nyuma yo guterwa urushinge. Byinshi muri byo birashira mu masaha 6-8 ya mbere binyuze mu kunyara no guhumeka bisanzwe.

Ushobora gusubira mu bikorwa byawe byose bisanzwe ako kanya nyuma yo gupimwa, harimo kuba hafi y'abana, abagore batwite, n'amatungo. Imirasire ihuye n'iyo wakira mu bisanzwe mu mezi make.

Ibikorwa bimwe na bimwe byemeza kunywa amazi menshi umunsi wose kugira ngo bifashe gukuramo umuti wihuse. Ibi ni ukwirinda aho kuba ngombwa mu buvuzi, ariko bishobora gutanga umutuzo niba ufite impungenge z'imirasire.

Q5. Nshobora kwitwara mu rugo nyuma yo guhabwa Fludeoxyglucose F-18?

Yego, urashobora kwitwara mu rugo nyuma yo guterwa urushinge no gupimwa. Isukari ifite imirasire ntigira ingaruka ku bwenge bwawe, imikoranire, cyangwa ubushobozi bwo gutwara ikinyabiziga mu buryo bwizewe.

Inzitizi imwe rukumbi yo gutwara ishobora kuva ku miti igabanya ubwoba niba wakiriye imiti igabanya ubwoba kugira ngo ifashe guhangana n'ubwoba bwo gufungirwa mu gihe cyo gupimwa. Niba wakiriye imiti iyo ari yo yose igabanya ubwoba, uzakenera undi muntu wo kukujyana mu rugo.

Abantu benshi bumva bameze neza nyuma yo gupimwa kwa PET kandi bashobora gusubira ku kazi, gukora imyitozo, n'ibindi bikorwa bisanzwe nta nzitizi. Iyi nzira yateguwe kugira ngo ijyane n'imikorere yawe ya buri munsi nta gihombo kinini.