Icyo Gadoxetate Aricyo: Ibyo Ikoreshwa, Uburyo Bwo Kuyifata, Ingaruka Zayo n'Ibindi

Gadoxetate ni umuti wihariye ukoreshwa mugihe cyo gukoresha MRI kugirango ifashe abaganga kureba neza umwijima wawe n'inzira z'igifu. Tekereza nk'igikoresho cyo gushimangira gituma ibice bimwe by'umubiri wawe bigaragara neza ku mashusho y'ubuvuzi, kimwe n'uko umukara wandika utuma inyandiko igaragara ku mpapuro.

Uyu muti ubarirwa mu itsinda ryitwa ibintu bitandukanye bishingiye kuri gadolinium. Bitangwa binyuze mu murongo wa IV mugihe cyo gukoresha MRI yawe kandi bikora bihindura by'agateganyo uburyo imitsi y'umwijima wawe igaragara ku mashusho ya scan.

Gadoxetate Ikoreshwa Kuri Iki?

Gadoxetate ikoreshwa cyane cyane mu gufasha abaganga kumenya no gusuzuma ibibazo by'umwijima mugihe cyo gukoresha MRI. Muganga wawe ashobora kugusaba uyu muti mugihe bakeneye ishusho isobanutse y'ibiri kuba mu mwijima wawe.

Uyu muti ufasha kumenya uburwayi butandukanye bw'umwijima burimo ibibyimba, ibyuririzi, n'ibindi bidasanzwe bishobora kutagaragara neza kuri MRI isanzwe. Bifitiye akamaro cyane cyane kumenya ibisebe bito by'umwijima bishobora kuburirwa iyo hatabayeho kongera umuti.

Abaganga kandi bakoresha gadoxetate kugirango basuzume uburyo umwijima wawe ukora neza no kureba inzira zawe z'igifu kugirango barebe niba hari ibiziba cyangwa ibindi bibazo. Iyi shusho irambuye ifasha ikipe yawe y'ubuzima gukora isuzuma ryukuri no gutegura imiti.

Gadoxetate Ikora Gute?

Gadoxetate ikora ikoreshwa byihariye n'uturemangingo tw'umwijima twiza, bituma bigaragara neza ku mashusho ya MRI. Iyi mikorere yihariye itanga itandukaniro riri hagati y'imitsi isanzwe y'umwijima n'ahantu hashobora kugira ibibazo.

Iyo yatewe mu maraso yawe, umuti ugenda mu mubiri wawe wose ariko ukibanda mu mwijima wawe mumunota. Uturemangingo tw'umwijima twiza dufata umuti, mugihe ahantu hangiritse cyangwa hadasanzwe ntibawufata neza, bituma habaho itandukaniro ridasanzwe kuri scan.

Umubiri wawe usohora gadoxetate mu buryo busanzwe unyuze mu mpyiko zawe no mu mwijima wawe. Hafi kimwe cya kabiri cyayo gishirwa mu nkari zawe, mu gihe kimwe cya kabiri kinyura mu bile byawe kikagenda kinyuze mu nzira yo mu gifu.

Nkwiriye Gufata Gaxodete Gute?

Mu by'ukuri ntabwo wifata gadoxetate ubwawe - itangwa n'umuganga unyuze mu muyoboro wa IV mu gihe cyo gufata ishusho ya MRI yawe. Umuti uterwa mu urugingo rw'umubiri rwawe, akenshi mu gihe gito.

Mbere yo gufata ishusho, urashobora kurya no kunywa ibisanzwe keretse muganga wawe akugiriye izindi nama. Abantu benshi ntibakeneye gukora impinduka zidasanzwe mu mirire mbere yo guhabwa gadoxetate.

Umuti uterwa igihe uryamye mu mashini ya MRI, kandi birashoboka ko uzawuhabwa hagati mu isesengura ryawe. Urashobora kumva umuvumo igihe umuti winjiye mu maraso yawe, ariko ibi ni ibisanzwe.

Nkwiriye Gufata Gadoxetate Igihe Kingana Gite?

Gadoxetate ni urushinge rumwe rutangwa gusa mu gihe cyo gusesengura kwa MRI. Ntabwo uzakenera gufata uyu muti uri mu rugo cyangwa ukomeze kuwufata nyuma yo gufata ishusho.

Ingaruka z'umuti zifata igihe gihagije kugirango isesengura ryawe rya MRI rirangire, akenshi mu minota 30 kugeza kuri 60. Umubiri wawe utangira gusohora umuti ako kanya nyuma yo kuwutera.

Gadoxetate nyinshi izavanwa mu mubiri wawe mu masaha 24 unyuze mu mikorere isanzwe y'impyiko zawe n'umwijima. Nta kintu na kimwe ugomba gukora kugirango ufashishe umubiri wawe kuyisohora.

Ni Iyihe Ngaruka Ziterwa na Gadoxetate?

Abantu benshi bafata neza gadoxetate, ingaruka zikaba zoroheje kandi z'igihe gito. Ibimenyetso bikunze kugaragara bibaho mu gihe cyangwa nyuma gato yo gutera umuti kandi akenshi bikemuka byonyine.

Dore ingaruka ushobora guhura nazo, wibuke ko abantu benshi badafite ingaruka na zimwe:

Ingaruka zisanzwe zirimo:

• Kumva ushyushye cyangwa umubiri uhindutse ibara igihe baterwa urushinge
• Kumva umunwa uryana nk'icyuma
• Urugimbu ruto
• Umutwe
• Urugero
• Kutoroherwa aho batera urushinge

Ibi bimenyetso bikunda kumara akanya gato kandi ntibisaba kuvurwa. Kumva ushyushye no kumva umunwa uryana ni ibintu bikunda kugaragara cyane kandi bisanzwe rwose iyo umuntu ahabwa urwo ruvange.

Ingaruka zitagaragara cyane ariko zikomeye zirimo:

• Uko kwifata kw'umubiri ku bintu bitandukanye bigaragarira mu mibumbe cyangwa amabara ku ruhu
• Kubura umwuka
• Kubyimba mu maso, iminwa, cyangwa umuhogo
• Urugimbu rukabije cyangwa kuruka
• Urubavu rubabaza cyangwa umutima utera nabi
• Urugero rukabije cyangwa kugwa igihumure

Nubwo izi ngaruka zikomeye zitagaragara kenshi, zisaba ubufasha bwihuse bw'abaganga. Itsinda ry'abaganga rikora isuzuma ryawe ryatojwe kumenya no kuvura izi ngaruka vuba niba zibaye.

Ibikomere bitagaragara cyane ariko bikomeye birimo:

• Fibrosis ya sisitemu ya nephrogenic (ku bantu barwaye indwara zikomeye z'impyiko)
• Uko kwifata kw'umubiri ku bintu bitandukanye bikabije (anaphylaxis)
• Ibibazo by'impyiko ku bantu barwaye indwara z'impyiko

Izi ngaruka zikomeye ntizikunda kubaho, cyane cyane ku bantu bafite imikorere isanzwe y'impyiko. Muganga wawe azasuzuma ubuzima bw'impyiko zawe mbere yo kugusaba gadoxetate kugirango agabanye izi ngaruka.

Ninde utagomba gufata Gadoxetate?

Gadoxetate ntibereye buri wese, kandi muganga wawe azasuzuma neza amateka yawe y'ubuzima mbere yo kugusaba uru ruvange. Abantu bafite indwara zimwe na zimwe bashobora gukenera uburyo bwo gupima butandukanye.

Ntabwo ukwiye guhabwa gadoxetate niba urwaye indwara zikomeye z'impyiko cyangwa guhagarara kw'impyiko. Abantu bafite imikorere y'impyiko igabanutse cyane (urugero rwo gupima glomerular filtration rate munsi ya 30) bahura n'ibibazo bikomeye.

Abafite allergie izwi kuri ibintu bifashishwa mu kugaragaza ibintu byifashisha gadolinium bagomba kwirinda gadoxetate. Niba waragize ikibazo gikomeye kubera ikintu icyo aricyo cyose cyifashishwa mu kugaragaza ibintu mbere, gerageza kubibwira ikipe y'ubuzima mbere yo kujya mu gihe cyo kwisuzumisha.

Abagore batwite akenshi birinda gadoxetate keretse inyungu zishoboka zigaragaza neza ko ziruta ibyago. Nubwo nta kimenyetso cy'ingorane ku bana bakiri bato, abaganga bakunda gukoresha uburyo bwo kugaragaza ibintu bundi bushya igihe bishoboka mu gihe cyo gutwita.

Abantu bafite indwara zimwe na zimwe z'umwijima, cyane cyane guhagarara gukora kw'umwijima, ntibashobora kuba abakandida beza ba gadoxetate kuko umuti wifashisha imikorere y'umwijima kugira ngo usohoke mu mubiri.

Amazina y'ubwoko bwa Gadoxetate

Gadoxetate iboneka munsi y'izina ry'ubwoko rya Eovist muri Leta Zunze Ubumwe za Amerika na Kanada. Mu Burayi no mu bindi bice by'isi, icuruzwa nka Primovist.

Ayo mazina yombi y'ubwoko yerekeza ku muti umwe - gadoxetate disodium - kandi akora kimwe mu kugaragaza ibintu by'umwijima bya MRI. Guhitamo hagati y'ubwoko akenshi biterwa n'icyo kiboneka muri sisitemu yawe y'ubuzima.

Uburyo bwo gusimbuza Gadoxetate

Ibindi bintu byinshi bifashishwa mu kugaragaza ibintu bishobora gukoreshwa mu kugaragaza ibintu by'umwijima bya MRI, nubwo buri kimwe gifite imitungo itandukanye n'imikoreshereze. Muganga wawe azahitamo uburyo bwiza bushingiye ku miterere yawe yihariye n'amakuru bakeneye kuva mu isuzuma ryawe.

Ibindi bintu bifashishwa mu kugaragaza ibintu bifashisha gadolinium nka gadopentetate (Magnevist) cyangwa gadobenate (MultiHance) bishobora gutanga ishusho y'umwijima, ariko ntibifite imitungo imwe yo gufata umwijima nka gadoxetate.

Kubera indwara zimwe na zimwe z'umwijima, muganga wawe ashobora kugusaba MRI isanzwe idafite ibintu bifashishwa mu kugaragaza ibintu, ultrasound, cyangwa isuzuma rya CT aho. Guhitamo biterwa n'icyo muganga wawe ashaka kandi n'imiterere yawe y'ubuzima bwite.

Ese Gadoxetate iruta ibindi bintu bifashishwa mu kugaragaza ibintu by'umwijima?

Gadoxetate itanga inyungu zidasanzwe mu ishusho y'umwijima, bigatuma ikoreshwa cyane mu bihe bimwe na bimwe. Ubushobozi bwayo bwo gukoreshwa by'umwihariko n'uturemangingo tw'umwijima butanga amakuru atabonwa mu bindi binyabutabara.

Ugereranije n'ibinyabutabara bisanzwe, gadoxetate iha abaganga amakuru abiri: uko amaraso atembera mu mwijima wawe n'uko uturemangingo tw'umwijima wawe dukora neza. Ubu bushobozi bubiri butuma bifasha cyane mu kumenya ibibyimba bito by'umwijima.

Ariko,

Kubera ko gadoxetate itangwa gusa mu gihe cy'amasaha yagenwe ya MRI, gusiba gahunda yawe bisobanura kongera gutegura isesengura ryawe ryose. Vugana n'umuganga wawe cyangwa ikigo gishinzwe gukora isesengura vuba bishoboka kugira ngo wongere utegure.

Ntugahagarike umutima kubera gusiba umuti ubwawo - nta ngaruka zo kuva ku muti cyangwa ibibazo byo kutabona gadoxetate. Ikintu cy'ingenzi ni ukubona isesengura ryawe ry'ubuvuzi rikoreshwa mu gihe.

Q4. Ni ryari nshobora gusubira mu bikorwa bisanzwe nyuma yo guhabwa gadoxetate?

Muri rusange ushobora gusubira mu bikorwa byawe byose bisanzwe ako kanya nyuma yo gukoresha MRI yawe na gadoxetate. Abantu benshi bumva bameze neza rwose kandi bashobora kwitwara mu rugo, gukora, no kwitabira ibikorwa bisanzwe.

Niba wumva uribwa umutwe cyangwa wumva utameze neza nyuma yo guterwa urushinge, tegereza kugeza ibyo bimenyetso bishize mbere yo gutwara imodoka cyangwa gukoresha imashini. Izi ngaruka zikunze kuba ngufi kandi zoroshye.

Q5. Nshobora konka nyuma yo guhabwa gadoxetate?

Amabwiriza y'ubuvuzi ya none avuga ko konka bishobora gukomeza bisanzwe nyuma yo guhabwa gadoxetate. Gusa umubare muto cyane w'umuti winjira mu mata y'ibere, kandi ntugenda neza mu bana banyuze mu nzira yo mu gifu.

Niba ufite impungenge, urashobora kuvoma no kumenesha amata y'ibere mu masaha 24 nyuma yo gukoresha isesengura ryawe, nubwo iyi ngamba itari ngombwa mu by'ubuvuzi. Ganira n'umuganga wawe ku bijyanye n'uko ubuzima bwawe buhagaze niba ufite ibibazo byerekeye konka nyuma ya gadoxetate.