Icyo Hemin Arimara: Ibyo Ikoreshwa, Uburyo Bwo Kuyifata, Ingaruka Zayo n'Ibindi

Hemin ni umuti wihariye wandikirwa na muganga urimo icyuma kandi utangwa unyuze mu muyoboro w'amaraso (IV) ukagezwa mu maraso yawe. Uyu muti ukoreshwa by'umwihariko mu kuvura indwara zidakunze kuboneka ariko zikomeye zizwi nka porphyrias zikomeye, zibaho iyo umubiri wawe ugize ikibazo cyo gukora ikintu cyitwa heme cy'ingenzi ku buzima bw'uturemangingo tw'amaraso.

Tekereza hemin nk'umuti ugamije gutabara ukoreshwa iyo umubiri wawe utangiye gukora heme mu buryo butunganye. Si umuti ushobora guhura nawo mu buvuzi bwa buri munsi, ariko ku bantu bawukeneye, hemin ishobora kuba ikiraro cy'ubuzima mu kubafasha gusubiza ubuzima mu buryo bwiza mu mikorere y'ingenzi y'umubiri.

Hemin Ikoreshwa ku Iki?

Hemin ikoreshwa cyane cyane mu kuvura ibitero bikomeye bya porphyria, cyane cyane porphyria ikomeye idahoraho, hereditary coproporphyria, na variegate porphyria. Izi ni indwara zidakunze kuboneka ziterwa n'imiterere ya kamere aho umubiri wawe udashobora gukora heme neza, bigatuma habaho kwiyongera kw'ibintu byangiza byitwa porphyrins.

Mugihe cyo kugaba igitero cya porphyria gikomeye, ushobora guhura n'ububabare bukomeye mu nda, isesemi, kuruka, ndetse n'ibimenyetso byo mu bwonko nk'urujijo cyangwa intege nke mu mikaya. Hemin ikora itanga heme umubiri wawe ukeneye, ibyo bikaba bifasha guhagarika umusaruro mwinshi wa porphyrins zangiza.

Muganga wawe ashobora kandi gutekereza hemin niba ufite ibitero bikomeza kugutera ingaruka zikomeye ku buzima bwawe. Mu bihe bimwe na bimwe, irashobora gukoreshwa mu buryo bwo kwirinda ku bantu bahura n'ibihe bikomeye kandi bikunze kubaho.

Hemin Ikora Gute?

Hemin ikora itanga umubiri wawe heme yoroshye gukoresha. Iyo ufite porphyria, inzira umubiri wawe ukoresha mu gukora heme irahungabana, bigatuma habaho ibintu byinshi byo hagati biba bigira uburozi.

Mu kuguha hemin binyuze mu urushinge mu urwungano rw'amaraso, umuti uba ubwira umubiri wawe kugabanya imbaraga zawo zo gukora heme mu buryo busanzwe. Ibi bigabanya ikorwa ry'izo porphyrin zangiza ziteza ibimenyetso byawe. Bimeze nk'uko utanga inzira yihuse yirengagiza igice cyangiritse cy'uruganda rw'umubiri wawe.

Hemin ifatwa nk'umuti ukomeye kuko ugira ingaruka zikomeye ku mikorere y'uturemangingo twawo. Ingaruka zikunze gutangira mu masaha 24 kugeza kuri 48 nyuma yo kuwutanga, nubwo abantu bamwe bashobora kubona impinduka mbere y'igihe.

Nkwiriye gufata hemin nte?

Hemin itangwa gusa binyuze mu urushinge mu urwungano rw'amaraso n'abakozi b'ubuzima mu bitaro cyangwa ahantu hakorerwa ibizamini by'ubuzima. Ntushobora gufata uyu muti mu rugo cyangwa unywa. Uyu muti uza mu ifu igomba kuvangwa n'amazi atagira mikorobe hanyuma ugatangwa binyuze mu murongo wa IV mu minota 15 kugeza kuri 30.

Mbere yo guterwa urushinge, ikipe yawe y'ubuzima irashobora gutangiza umurongo wa IV kandi irashobora kuguha imiti yo gukumira ingaruka zishobora kubaho. Ntabwo ukeneye kwiyiriza mbere yo guhabwa hemin, kandi nta mbogamizi zidasanzwe z'imirire, nubwo kuguma ufite amazi ahagije bifasha buri gihe.

Urushinge ubwarwo rukunze gutangwa rimwe ku munsi mu gihe cy'iminsi ine, bitewe n'uburemere bw'icyo gitero ufite n'uburyo witwara ku buvuzi. Ikipe yawe y'ubuvuzi izagukurikiranira hafi mu gihe cyose no nyuma ya buri rushinge kugirango irebe niba hari icyo byateza.

Nkwiriye gufata hemin igihe kingana iki?

Abantu benshi bahabwa hemin mu gihe cy'iminsi 3 kugeza kuri 4 mu gihe cy'igitero gikomeye cya porphyria. Igihe nyacyo giterwa n'uburyo ibimenyetso byawe bikira vuba n'uburyo umubiri wawe witwara ku buvuzi.

Muganga wawe azasuzuma uko urimo utera imbere buri munsi kandi ashobora guhagarika ubuvuzi igihe ibimenyetso byawe bitangiye gukira cyane. Abantu bamwe barumva barushijeho kumera neza nyuma yo gufata doze imwe cyangwa ebyiri gusa, mu gihe abandi bashobora gukenera iminsi ine yose.

Ku bantu bagira ibitero kenshi, muganga wawe ashobora kuganira kuri gahunda yo kubungabunga, ariko ibi byaba bigenewe umuntu ku giti cye hashingiwe ku burwayi bwe bwihariye n'amateka ye y'ubuvuzi. Intego ni ukoresha imiti mike ikora neza mugihe ugukingira no kugufasha kumva umeze neza.

Ni Ibihe Bikorwa Bigaragara Byo Gukoresha Hemin?

Kimwe n'imiti yose, hemin ishobora gutera ibikorwa bigaragara, nubwo atari buri wese ubyumva. Ibikorwa bigaragara cyane akenshi biroroshye kandi birashoboka kubungabungwa n'ubuyobozi bw'ubuvuzi bukwiye.

Dore ibikorwa bigaragara cyane ushobora guhura nabyo:

• Urubavu cyangwa kwishima ahantu batera urushinge
• Umutwe
• Isesemi
• Urubavu
• Impinduka z'agateganyo mu bizami byo gupfuka kw'amaraso
• Impinduka z'agateganyo mu mikorere y'impyiko

Ibi bikorwa bigaragara bisanzwe bikemuka byonyine cyangwa hamwe n'ubufasha. Itsinda ryawe ry'ubuzima rizakurikirana neza kandi rishobora gutanga imiti yo gufasha gukemura ibibazo byose.

Ibikorwa bikomeye ariko bitagaragara cyane bishobora kuba birimo:

• Urugero rw'ibimenyetso by'uburwayi hamwe n'ibibara, kwishima, cyangwa guhumeka bigoranye
• Ibibazo byo gupfuka kw'amaraso
• Impinduka zikomeye mu mikorere y'impyiko
• Ibikorwa bikomeye ahantu batera urushinge

Nubwo ibi bikorwa bikomeye bidasanzwe, bisaba ubufasha bw'ubuvuzi bwihuse. Inkuru nziza ni uko uzaba uri mu kigo cy'ubuvuzi aho ibi bishobora kumenyekana no kuvurwa vuba.

Ibikomere bidasanzwe cyane ariko bikomeye bishobora kuba birimo ibimenyetso bikomeye by'uburwayi cyangwa impinduka zikomeye mu mikorere y'amaraso. Itsinda ryawe ry'ubuvuzi ryatojwe gukurikirana ibi no gusubiza ako kanya nibiba.

Ninde Utagomba Gufata Hemin?

Hemin ntabwo ikwiriye kuri buri wese, kandi muganga wawe azasuzuma neza niba bikwiriye kuri wowe. Abantu bafite allergie zizwi kuri hemin cyangwa ibice byayo ntibagomba guhabwa uyu muti.

Muganga wawe azitonda cyane niba ufite indwara zimwe na zimwe zishobora gutuma hemin iba ingorane kuri wowe. Izi zirimo indwara zikomeye z'impyiko, indwara zimwe na zimwe zitera amaraso, cyangwa amateka y'uburwayi bukomeye bwo kwibasirwa n'imiti irimo icyuma.

Abagore batwite kandi bonka bagomba kwitabwaho by'umwihariko, kuko umutekano wa hemin mugihe cyo gutwita no konsa utarashyirwaho neza. Muganga wawe azagereranya inyungu zishoboka n'ibishobora kuba byose niba uri muri imwe muri izi ngorane.

Abantu bafite ubwoko bumwe bwa porphyria butitabira hemin, nk'uburyo bumwe bwa porphyria ya cutaneous, mubisanzwe ntibazaba abakandida bo kuvurwa nk'uku.

Amazina ya Hemin Brand

Izina risanzwe riboneka kuri hemin muri Leta Zunze Ubumwe z'Amerika ni Panhematin. Iyi ni formulation ikoreshwa cyane n'ibitaro n'ibigo by'ubuvuzi mugihe cyo kuvura ibitero bya porphyria.

Ibihugu bimwe bishobora kugira amazina atandukanye ya brand cyangwa formulations, ariko ibikoresho bikora biracyari kimwe. Itsinda ryawe ry'ubuzima rizagufasha kubona formulation ikwiye hatitawe ku izina ryihariye rya brand.

Ubwoko bwa generic bwa hemin bushobora kuboneka ahantu hamwe, ariko muganga wawe azahitamo uburyo bukwiye cyane bitewe n'uko biboneka n'ibikenewe byawe by'ubuvuzi.

Uburyo bwa Hemin

Kubera ibitero bya porphyria, hemin akenshi ni uburyo bwa mbere bwo kuvura, ariko hariho ubundi buryo muganga wawe ashobora gutekereza. Givosiran ni umuti mushya ushobora gufasha kwirinda ibitero kubantu bafite porphyria ihoraho, nubwo ikora muburyo butandukanye na hemin.

Ubufasha bwo kwitabwaho burakenewe kandi bushobora gushyiramo gucunga ububabare, amazi ya IV, n'imiti yo kugenzura isesemi no kuruka. Rimwe na rimwe izi mvura zishobora gufasha gucunga ibitero byoroheje.

Mu rwego rwo kwirinda ibitero bizaza, muganga wawe ashobora kugusaba kwirinda ibintu bizwi bitera uburwayi, kurya neza, no kugabanya umunaniro. Abantu bamwe bungukirwa no guterwa inshinge za glucose buri gihe cyangwa izindi ngamba zo kwirinda.

Mu bihe bidasanzwe cyane aho hemin itaboneka cyangwa idakwiriye, izindi ntungamubiri zisa na heme zakoreshejwe, ariko ibi bikunze gukoreshwa mu bihe by'ubutabazi gusa.

Ese Hemin iruta izindi nshuti zo kuvura porphyria?

Hemin akenshi ifatwa nk'urugero rwiza rwo kuvura ibitero bikaze bya porphyria kuko ikemura ikibazo cy'ibanze gitanga heme umubiri wawe ukeneye. Akenshi irakora neza kurusha ubuvuzi bushingiye gusa ku gufasha mu bitero byoroheje kugeza ku bikaze.

Ugereranije n'imiti mishya nka givosiran, hemin ikora ako kanya mu gihe cy'igitero gikaze, mu gihe givosiran yibanda cyane ku kwirinda ibitero bizaza. Bakora ibintu bitandukanye, kandi abantu bamwe bashobora kungukirwa n'uburyo bwombi.

Gu hitamo hagati ya hemin n'izindi nshuti bitewe n'ibintu byinshi, harimo ubukana bw'igitero cyawe, amateka yawe y'ubuvuzi, n'ibiboneka mu kigo kivuriramo. Muganga wawe azahitamo uburyo bushobora kugufasha vuba kandi neza.

Ku bitero byoroheje, ubuvuzi bushingiye ku gufasha gusa bushobora kuba buhagije, ariko ku bihe bikaze cyane, uburyo bwa hemin bugamije akenshi butanga ubufasha bwihuse kandi bwuzuye.

Ibikunze kubazwa kuri Hemin

Ese Hemin irakwiriye ku bantu barwaye indwara z'impyiko?

Hemin isaba kwitonderwa cyane ku bantu barwaye indwara z'impyiko kuko ishobora guhindura imikorere y'impyiko by'agateganyo. Muganga wawe azagenzura imikorere y'impyiko yawe neza mbere, mu gihe, na nyuma yo kuvurwa.

Niba ufite ibibazo byoroheje by'impyiko, urashobora kuba ugishobora guhabwa hemin hamwe no kugenzura by'inyongera ndetse no guhindura imiti. Ariko, niba ufite indwara zikomeye z'impyiko, muganga wawe ashobora gukenera gupima inyungu n'ibibazo byinshi.

Ninkora iki niba ngize ibimenyetso bikomeye mugihe mvurwa na Hemin?

Niba ubonye ibimenyetso nk'ingorane zo guhumeka, uruhu rururuka cyane, kuribwa mu gituza, cyangwa kubabara umutwe cyane mu gihe uvurwa na hemin, menyesha ikipe yawe y'abaganga ako kanya. Ibi bishobora kuba ibimenyetso byo kwibasirwa n'umubiri bikomeye cyangwa izindi ngorane.

Inkuru nziza ni uko uzaba uri mu kigo cy'ubuvuzi aho ibi bimenyetso bishobora kumenyekana no kuvurwa vuba. Ikipe yawe y'ubuzima yatojwe gucunga ibi bihe kandi ifite imiti yihutirwa ihari.

Nshobora gutwara imodoka nyuma yo guhabwa Hemin?

Ntabwo ugomba gutwara imodoka ako kanya nyuma yo guhabwa hemin, cyane cyane niba wagaragaje ingaruka nk'izungera, kubabara umutwe, cyangwa kunanirwa. Abantu benshi bahabwa hemin bararwaye cyane kubera igitero cyabo cya porphyria kandi bakeneye igihe cyo koroherwa.

Muganga wawe azakumenyesha igihe bizaba byemewe gusubira mu bikorwa bisanzwe, harimo no gutwara imodoka. Iyi myanzuro ishingiye ku buryo wumva umeze niba waragize izindi ngaruka zituruka ku buvuzi.

Hemin ikora vuba gute?

Abantu benshi batangira kubona impinduka mu bimenyetso byabo mu masaha 24 kugeza kuri 48 nyuma yo gutangira kuvurwa na hemin. Abantu bamwe barumva barushijeho mbere, mu gihe abandi bashobora gufata uburyo bwose bwo kuvurwa kugirango babone impinduka zigaragara.

Urubavu, akenshi ari ikimenyetso gikomeye, akenshi rurushaho mbere. Ibindi bimenyetso nk'isuka n'ingaruka za neurologique bishobora gufata igihe gito kugirango bikemuke rwose.

Nzongera gukenera Hemin mu gihe kizaza?

Niba uzongera gukenera hemin biterwa n'uburwayi bwawe bwite n'uburyo ushobora gucunga ibitera porphyria yawe. Abantu bamwe bagira igitero kimwe cyangwa bibiri gusa mu buzima bwabo, mu gihe abandi bashobora gukenera kuvurwa kenshi.

Umuvuzi wawe azakorana nawe kugira ngo mutegure gahunda y'igihe kirekire ishobora kuba irimo kwirinda ibitera uburwayi, imiti y'ubwirinzi, cyangwa gutegura gahunda y'ibitero bizaza. Intego ni ukugabanya gukenera kuvura inshuro nyinshi na hemin mugihe ugukomeza ufite ubuzima bwiza kandi wishimye.