Icyo Ibandronate Arimara: Ibikoreshwa, Uburyo Bwo Gufata, Ingaruka Zishobora Kugaragara n'ibindi

Ibandronate ni umuti wandikirwa na muganga ufasha gukomeza amagufa yawe mu kugabanya uburyo amagufa asenyuka. Uyu muti ubarirwa mu itsinda ry'imiti yitwa bisphosphonates, ikora nk'abarinda urugero rw'amagufa yawe. Uyu muti ukoreshwa cyane mu kuvura no gukumira indwara ya osteoporosis, cyane cyane ku bagore bamaze guca imbyaro igihe amagufa asanzwe agera aho acika intege.

Icyo Ibandronate Aricyo?

Ibandronate ni umuti ukomeza amagufa ubarirwa mu muryango wa bisphosphonate. Wibuke ko ari nk'abakozi bakora isuku ku magufa yawe - ifasha gukumira isenyuka risanzwe rishobora gutuma amagufa acika intege, agacika mu gihe.

Amagufa yawe ahora yongera kwiyubaka binyuze mu buryo aho imitsi ya kera y'amagufa ikurwaho hanyuma imitsi mishya igasimbura. Ibandronate ikora mu kugabanya igice cyo gukuraho ubu buryo, ikemerera amagufa yawe gukomeza imbaraga zayo n'ubucucike. Ibi bituma bifitiye akamaro kanini abantu amagufa yabo yacitse intege cyane kubera gusaza cyangwa impinduka za hormone.

Uyu muti uza mu buryo bw'ibinini kandi ufashwe mu kanwa, bigatuma biba uburyo bworoshye bwo gucunga ubuzima bw'amagufa igihe kirekire. Urukoreshwa mu buryo bwizewe n'abantu babarirwa muri miliyoni ku isi hose kuva rwatangira kwemezwa gukoreshwa mu buvuzi.

Icyo Ibandronate Ikoreshwa?

Ibandronate ikoreshwa cyane mu kuvura no gukumira osteoporosis ku bagore bamaze guca imbyaro. Osteoporosis ni indwara aho amagufa acika intege cyane ku buryo ashobora kuvunika byoroshye kubera kugwa guto cyangwa ndetse n'ibikorwa bisanzwe bya buri munsi.

Muganga wawe ashobora kugusaba ibandronate niba warasanzwemo indwara ya osteoporosis binyuze mu igeragezwa ry'ubucucike bw'amagufa. Uyu muti kandi ukoreshwa mu gukumira osteoporosis ku bagore bari mu kaga ko kurwara iyi ndwara kubera ibintu nk'amateka y'umuryango, guca imbyaro kare, cyangwa gukoresha imiti imwe na rimwe igihe kirekire nka steroids.

Mu bindi bihe, abaganga bashobora kwandikira ibandronate abagabo bafite umugongo, nubwo ibyo bidakunze kubaho. Uyu muti ushobora no gukoreshwa mu kuvura ibibazo by'amagufa biterwa na kanseri zimwe na zimwe, nubwo ibyo bisaba gukurikiranwa neza n'ikipe yawe y'ubuvuzi.

Ibandronate ikora ite?

Ibandronate ikora yerekeza ku turemangingo twihariye two mu magufa yawe twitwa osteoclasts. Utu turemangingo niyo dusenyera imitsi ya kera y'amagufa nk'igice cy'umubiri wawe gisanzwe cyo kuvugurura amagufa.

Iyo ufata ibandronate, yinjira mu gice cy'amagufa yawe kandi mu by'ukuri ishyira feri kuri utu turemangingo dusenya amagufa. Ibi bituma uturemangingo twubaka amagufa, twitwa osteoblasts, dukora neza cyane hatagomba guhangana no gusenywa kw'amagufa cyane. Ibyo bigira ingaruka zo gukomera kw'amagufa no kuyashyira hamwe uko igihe kigenda.

Uyu muti ufatwa nk'ukomeye cyane mu miti y'amagufa. Ntabwo ukomeye nk'imiti imwe na imwe ya bisphosphonates ikoreshwa mu nshinge, ariko irakora neza kurusha gusa calcium na vitamine D. Abantu benshi batangira kubona impinduka mu magufa yabo hagati y'amezi 6 na 12 nyuma yo gutangira kuvurwa.

Nkwiriye gufata Ibandronate nte?

Gufata ibandronate neza ni ngombwa kugira ngo ikore neza kandi no ku mutekano wawe. Uyu muti ugomba gufatwa ku gifu cyambaye ubusa, mu gitondo kare, hamwe n'ikirahure cyuzuye cy'amazi asanzwe.

Uku niko ugomba kuyifata: Byuka ufate tablet yawe ya ibandronate ako kanya hamwe na 6 kugeza kuri 8 ounces z'amazi asanzwe. Ntukarye, ntunywe ikindi kintu, cyangwa ngo ufate indi miti nibura iminota 60 nyuma yaho. Muri iki gihe cyo gutegereza, guma uhagaze - waba wicaye cyangwa uhagaze - kugira ngo ufashe umuti kugera mu gifu cyawe neza kandi wirinde kurakaza umuhogo wawe.

Irinde kunywa ibandronate hamwe na kawa, icyayi, umutobe, cyangwa amata, kuko ibi bishobora kubuza umubiri wawe gukoresha neza umuti. Nanone, ntukaryame byibuze isaha imwe umaze kuwufata, kuko ibi bishobora kongera ibyago byo kuribwa mu muhogo. Niba ukeneye gufata imiti yongera kalisiyumu cyangwa imiti igabanya aside, tegera byibuze amasaha abiri umaze gufata ibandronate.

Nzamara Igihe Kingana Giki Ndafata Ibandronate?

Abantu benshi bafata ibandronate imyaka myinshi, akenshi hagati y'imyaka 3 kugeza kuri 5 mu ntangiriro. Muganga wawe azakurikirana uko urimo witwara binyuze mu bipimo bya buri gihe by'ubucucike bw'amagufa n'ibizamini by'amaraso kugira ngo amenye igihe cyiza cyo gukoresha umuti ukurikije uko ubuzima bwawe bumeze.

Nyuma y'imyaka nka 3 kugeza kuri 5 uvurwa, muganga wawe ashobora kugusaba

Ibi ni bimwe mu ngaruka zikunze kugaragara zigaragara ku bantu bamwe:

• Kubabara mu nda cyangwa kutagira igogora
• Urugaruka cyangwa kuruka gake
• Impiswi cyangwa guhagarara kw'amazi
• Umutwe
• Kubabara imitsi cyangwa ingingo
• Urugero
• Ibimenyetso bisa n'ibicurane

Ibi bimenyetso mubisanzwe ntibigira ubukana kandi birashira. Niba bikomeje cyangwa bikaba bibangamiye, muganga wawe akenshi ashobora gutanga inama zo kubigabanya cyangwa guhindura gahunda yawe y'imiti.

Hariho kandi ingaruka zimwe na zimwe zitajegera ariko zikomeye zisaba ubufasha bwihuse bwa muganga. Nubwo ibi bitaba ku bantu benshi, ni ngombwa kubimenya.

Ingaruka zikomeye zisaba ubufasha bwihuse bwa muganga zirimo:

• Kubabara cyane mu gituza cyangwa kugorwa no kumira
• Urugaruka rukabije cyangwa kubabara mu nda
• Kubabara gushya cyangwa kudasanze mu itako, ikibuno, cyangwa mu gice cy'igihimba
• Kubabara mu ruhanga cyangwa guhumirwa
• Kubabara cyane mu magufa, ingingo, cyangwa imitsi
• Ibimenyetso byo kugabanuka kwa kalisiyumu (kuribwa kw'imitsi, kuribwa mu ntoki)

Niba ubonye ibi bimenyetso, vugana n'umuganga wawe ako kanya. Bashobora gufasha kumenya niba ibimenyetso bifitanye isano n'imiti yawe hanyuma bagahindura uburyo uvurwa niba bibaye ngombwa.

Ninde utagomba gufata Ibandronate?

Ibandronate ntabwo ikwiriye kuri buri wese, kandi hariho ibintu bimwe na bimwe n'ibihe iyi miti igomba kwirindwa. Muganga wawe azasuzuma neza amateka yawe y'ubuzima mbere yo kuyandika.

Ntabwo ugomba gufata ibandronate niba ufite ibibazo byo mu muhogo, nk'ugufungana cyangwa kugorwa no kumira. Uyu muti ushobora kurakaza urukuta rw'umuhogo wawe, cyane cyane niba ufite ibibazo mbere. Abantu badashobora kwicara cyangwa guhagarara neza byibuze iminota 60 bagomba kwirinda uyu muti.

Izindi ngorane zishobora kukubuza gufata ibandronate zirimo:

• Indwara ikaze y’impyiko
• Urugero rwo hasi cyane rwa kalisiyumu mu maraso
• Kutabasha gukora neza kalisiyumu
• Ibisebe bikaze byo mu gifu cyangwa mu ruyunguruzo rw’amara
• Indwara zimwe na zimwe zo mu muhogo
• Gusama cyangwa konsa

Muganga wawe azitonda kandi mu gutanga ibandronate niba ufite ibibazo by’amenyo, ufata imiti imwe na rimwe, cyangwa ufite amateka y’ibibazo byo mu ruhanga. Kuganira neza n’umuganga wawe ku mateka yawe yose y’ubuzima bifasha kumenya neza ko uyu muti ari mwiza kuri wowe.

Amazina y’ubwoko bwa Ibandronate

Ibandronate iboneka mu mazina y’ubwoko butandukanye, aho Boniva ariyo izwi cyane muri Leta Zunze Ubumwe z’Amerika. Ubu bwoko burimo ibintu bikora kimwe n’ubwoko rusange ariko bushobora kuba bufite ibindi bintu bitagira akamaro.

Andi mazina y’ubwoko ushobora guhura nayo harimo Bondronat mu bihugu bimwe na bimwe n’ubwoko butandukanye rusange bukoresha izina gusa “ibandronate sodium.” Uko wakwakira ubwoko bw’izina cyangwa ubwoko rusange, umuti ukora ni umwe kandi ufite akamaro kamwe.

Farumasi yawe ishobora guhita ishyiraho ubwoko rusange keretse muganga wawe asabye by’umwihariko izina ry’ubwoko. Ibi ni ibisanzwe kandi bishobora gufasha kugabanya amafaranga y’imiti yawe mugihe itanga inyungu zimwe za therapeutic.

Uburyo bwa Ibandronate bwo gusimbuza

Niba ibandronate atariyo ikwiriye kuri wowe, hariho ubundi buryo butandukanye bwiza bwo kuvura osteoporosis. Muganga wawe ashobora kugufasha kubona uburyo bwiza bushingiye ku byo ukeneye byihariye n’amateka yawe y’ubuzima.

Izindi miti ya bisphosphonate harimo alendronate (Fosamax), risedronate (Actonel), na zoledronic acid (Reclast). Izi zikora kimwe na ibandronate ariko zishobora kugira gahunda zitandukanye zo gutanga imiti cyangwa ingaruka zinyuranye. Abantu bamwe basanga bisphosphonate imwe yihanganirwa kurusha izindi.

Uburyo bwo gusimbuza butari bisphosphonate burimo:

• Denosumab (Prolia) - itangwa nk'urushinge buri mezi atandatu
• Teriparatide (Forteo) - urushinge rwa buri munsi rwubaka amagufa mashya
• Raloxifene (Evista) - ikinini cya buri munsi kigana ingaruka zo kurinda amagufa za estrojeni
• Calcitonin - iboneka nk'umuti uvuzwa mu mazuru cyangwa urushinge

Muganga wawe azatekereza ibintu nk'imyaka yawe, ubuzima muri rusange, imiti indi ufata, n'ibyo ukunda ku giti cyawe igihe asaba izindi nzira. Buri kimwe gifite inyungu zacyo n'ibitekerezo byacyo.

Ese Ibandronate iruta Alendronate?

Ibyombi, ibandronate na alendronate, ni bisphosphonates bikora neza mu kuvura umugogoro, ariko bifite itandukaniro ry'ingenzi rishobora gutuma kimwe gikwiriye kurusha ikindi.

Ibandronate ikunze gufatwa rimwe mu kwezi, naho alendronate ikunze gufatwa rimwe mu cyumweru. Iyi gahunda yo gufata imiti idakunze gukoreshwa irashobora korohereza abantu bamwe kandi ikongera imikoreshereze y'imiti. Ariko, alendronate yigishijwe cyane kandi ifite amateka maremare yo gukoreshwa.

Mu bijyanye n'imikorere, imiti yombi igabanya cyane ibyago byo kuvunika kandi ikongera ubwinshi bw'amagufa. Ubushakashatsi bumwe buvuga ko alendronate ishobora kugira akarusho gato mu gukumira kuvunika kw'ikibuno, naho ibandronate isa nkaho ikora kimwe mu kuvura kuvunika kw'umugongo. Imiterere y'ingaruka ziterwa ni kimwe, nubwo abantu bamwe bashobora kwihanganira kimwe kurusha ikindi.

Gu hitamo hagati y'iyi miti akenshi biterwa n'ibintu byawe bwite nk'uko ukunda gufata imiti, uko wihanganira buri muti, n'uburambe bw'umuganga wawe. Byombi ni amahitamo meza ku buzima bw'amagufa iyo bikoreshejwe neza.

Ibikunze Kubazwa ku Ibandronate

Ese Ibandronate irakwiriye ku bantu barwaye indwara z'umutima?

Yego, ibandronate muri rusange irakwiriye ku bantu barwaye indwara z'umutima. Bitandukanye n'indi miti, bisphosphonates nka ibandronate ntizikunze kugira ingaruka ku mikorere y'umutima cyangwa umuvuduko w'amaraso.

Ariko, ugomba kubwira muganga wawe ibyerekeye indwara zose z'umutima ufite. Bazashaka kumenya neza ko imiti yose urimo gufata ku mutima wawe idahura na ibandronate. Ikintu cy'ingenzi ni ukwemeza ko ushobora guhagarara neza mu gihe cy'isaha isabwa nyuma yo gufata umuti.

Nkwiriye gukora iki niba mfashe ibandronate nyinshi mu buryo butunganye?

Niba ufata ibandronate nyinshi mu buryo butunganye kuruta urugero rwanditswe, ntugahagarike umutima, ariko ukore icyo gikorwa ako kanya. Nywa ikirahure cyuzuye cy'amata cyangwa ufate ibinini bya kalisiyumu ako kanya kugira ngo bifashe guhagarika umuti mwinshi mu gifu cyawe.

Haguruka kandi uvugishe muganga wawe cyangwa ikigo gishinzwe kugenzura ubumara ako kanya. Ntugagerageze kwivugisha, kuko ibyo bishobora gutuma umuti urakaza umuhogo wawe cyane. Urugero rwinshi rwo kurenza urugero ntirugira ingaruka zikomeye, ariko ubujyanama bw'abaganga ni ingenzi kugira ngo umutekano wawe wemezwe.

Nkwiriye gukora iki niba nciwe urugero rwa ibandronate?

Niba ucikanwe urugero rwawe rwa buri kwezi rwa ibandronate, rufate ako kanya wibuka, ariko niba hashize iminsi itarenze 7 kuva ku rugero rwawe rwatanzwe. Kurikiza amabwiriza amwe nk'uko bisanzwe: ufate mu gitondo kare ku gifu cyambaye ubusa hamwe n'amazi.

Niba hashize iminsi irenga 7 kuva ku rugero rwawe rwatanzwe, rwirengagize kandi ufate urugero rwawe rutaha ku munsi wawe wari warateganyije. Ntukafate urugero rwa kabiri hafi kugira ngo wuzuze urugero rwatanzwe. Ibi bishobora kongera ibyago byo kugira ingaruka mbi zitagira inyungu zinyongera.

Nshobora guhagarika ryari gufata ibandronate?

Umwanzuro wo guhagarika gufata ibandronate ugomba gufatwa buri gihe hamwe n'ubuyobozi bwa muganga wawe. Abantu benshi babifata imyaka 3 kugeza kuri 5 mbere na mbere, nyuma yaho muganga wawe azasuzuma niba ukeneye gukomeza cyangwa ushobora kuruhuka.

Umuganga wawe azatekereza ibintu nk'ubucucike bw'amagufa yawe ubu, ibyago byo kuvunika, imyaka yawe, n'ubuzima bwawe muri rusange igihe afata icyemezo cyo guhagarika imiti. Abantu bamwe bashobora gukenera gukomeza igihe kirekire, mu gihe abandi bashobora kungukirwa no kuruhuka by'agateganyo. Ibizamini bya buri gihe byo gupima ubucucike bw'amagufa bifasha kuyobora iki cyemezo.

Nshobora gufata Ibandronate hamwe n'indi miti?

Ibandronate irashobora guhura n'indi miti myinshi, bityo ni ngombwa kubwira umuganga wawe ibyo ufata byose. Inyongeramirire ya kalisiyumu, imiti irwanya aside, n'inyongeramirire y'icyuma birashobora kugabanya cyane uburyo umubiri wawe winjiza ibandronate.

Fata izi nyongeramirire byibuze amasaha 2 nyuma yo gufata ibandronate. Indi miti ishobora guhura harimo imiti yica mikorobe, aspirine, n'imiti imwe yo kurwanya ububabare. Umuganga wawe cyangwa umufarumasiti ashobora gutanga urutonde rwuzuye rw'imiti yo kwirinda cyangwa gufata mu gihe gitandukanye n'urugero rwawe rwa ibandronate.