Indomethacine (Intravenous) ni iki: Ibikoreshwa, Urutonde rw'imiti, Ingaruka ziterwa n'iyo miti n'ibindi

Indomethacine intravenous ni umuti ukomeye urwanya kubyimbirwa utangwa mu maraso yawe unyuze mu muyoboro wa IV. Ubu bwoko bwa indomethacine bukoreshwa cyane cyane ku bana bavutse vuba kugira ngo bufashe gufunga indwara y'umutima yihariye yitwa patent ductus arteriosus, aho umuyoboro w'amaraso wagombaga gufunga nyuma yo kuvuka ukomeza gufunguka.

Bitandukanye n'uburyo bwo kunywa ushobora gufata kubera kuribwa mu ngingo, indomethacine ya IV igenewe ibibazo by'ubuvuzi byihariye mu bitaro. Ikora vuba kandi neza kuko yirengagiza rwose sisitemu yawe yo mu gifu.

Indomethacine ya IV ikoreshwa mu iki?

Indomethacine ya IV ifite icyo ikoreshwa cy'ibanze gitandukanye cyane n'icyo ikoreshwa mu kunywa. Yagenewe by'umwihariko kuvura patent ductus arteriosus (PDA) ku bana bavutse vuba.

PDA ibaho iyo umuyoboro w'amaraso witwa ductus arteriosus udafunga mu buryo busanzwe nyuma yo kuvuka nk'uko bikwiye. Uyu muyoboro ni ingenzi mugihe cyo gutwita ariko ugomba gufunga igihe umwana wawe atangiye guhumeka wenyine. Iyo ugumye ufunguye, bishobora gutera ibibazo byo guhumeka no gushyira umutwaro mwinshi ku mutima w'umwana wawe.

Uyu muti ufasha gutera inzira isanzwe yo gufunga yagombaga kuba yarabayeho mu buryo bwikora. Ubu buvuzi bwihariye akenshi bushobora kwirinda gukenera kubagwa, ibyo bikaba by'ingenzi cyane cyane ku bana bavutse vuba bafite intege nke.

Indomethacine ya IV ikora ite?

Indomethacine ya IV ni umuti ukomeye ukora ubuza imisemburo imwe n'imwe mu mubiri wawe yitwa prostaglandins. Iyi misemburo isanzwe ifungura ductus arteriosus mugihe cyo gutwita, ariko igomba guhagarara gukora nyuma yo kuvuka.

Tekereza prostaglandins nk'intumwa nto zibwira umuyoboro w'amaraso kuguma ufunguye. Indomethacine ihagarika ubu butumwa, ikemerera umuyoboro gufunga mu buryo busanzwe. Ubu buryo busanzwe bubaho mumasaha make kugeza kuminsi nyuma yo kuvurwa.

Uyu muti ukora cyane mu minsi ya mbere y'ubuzima igihe imitsi ya ductus arteriosus ikiri kwakira ibimenyetso bya chimique. Nyuma y'amasaha nka 72 avutse, umutsi ntushobora kwakira umuti wenyine.

Indomethacin IV igomba gutangwa gute?

Indomethacin IV itangwa n'abantu b'inzobere mu by'ubuvuzi bafite imyitozo mu bitaro cyangwa mu kigo kivura abana bakiri bato. Ntabwo bizagusaba kwitaho gutanga uyu muti wenyine.

Uyu muti utangwa buhoro buhoro binyuze mu muyoboro wa IV mu minota 20 kugeza kuri 30. Itsinda ry'abaganga bavura umwana wawe bazagenzura neza umuvuduko w'umutima we, umuvuduko w'amaraso, n'urugero rwa oxygen mu gihe cyo gutanga umuti no nyuma ya buri dose.

Abana benshi bahabwa doze eshatu zitangwa mu gihe cyagenwe, akenshi intera ya 12 kugeza kuri 24. Igihe nyacyo giterwa n'imyaka y'umwana wawe n'uburyo yakiriye dose ya mbere. Itsinda ry'abaganga bazahindura gahunda bitewe n'ibyo umwana wawe akeneye.

Indomethacin IV ivurwa igihe kingana iki?

Uburyo bwo kuvura busanzwe ni bugufi cyane, akenshi bumara iminsi mike gusa. Abana benshi bahabwa doze eshatu zikwirakwizwa mu minsi 2 kugeza kuri 3.

Itsinda ry'abaganga bazakoresha ultrasound kugirango barebe niba ductus arteriosus ifunga nyuma ya buri dose. Niba umutsi ufunze neza nyuma ya dose ya mbere cyangwa iya kabiri, ntihazaba hari undi muti ukenewe.

Niba doze eshatu zitafunze umutsi, muganga wawe ashobora gutekereza uburyo bwo kuvura bwa kabiri cyangwa akaganira ku buryo bwo kubaga. Icyemezo giterwa n'ubuzima bw'umwana wawe muri rusange n'uburyo umutsi ukeneye gufungwa byihutirwa.

Ni izihe ngaruka ziterwa na Indomethacin IV?

Kimwe n'imiti yose ikomeye, indomethacin IV ishobora gutera ingaruka, nubwo abana benshi bayihanganira neza. Itsinda ry'abaganga bazagenzura neza impinduka zose ziteye impungenge.

Dore ingaruka itsinda ry'abaganga bazagenzura neza, batangiriye ku zikunze kubaho:

• Kugabanyuka kw'inkari kuko impyiko zigabanya umurimo wazo by'agateganyo
• Impinduka mu gipimo cy'amaraso, haba kuzamuka cyangwa kumanuka birenze ibisanzwe
• Impinduka z'agateganyo mu bipimo by'imiti mu maraso
• Kongera ibyago byo kuva amaraso bitewe n'ingaruka ku mikoranire y'amaraso
• Kugabanyuka kw'umuvuduko w'umutima by'agateganyo
• Ingaruka ku igogora nk'ugabanya ubushobozi bwo kurya

Ingaruka zikomeye ariko zitabaho kenshi zirimo ibibazo bikomeye by'impyiko, kuva amaraso cyane, cyangwa impinduka mu mikoranire y'umutima. Itsinda ry'abaganga bafite uburambe bwo gukemura ibi bibazo kandi bazahindura imiti niba hari ibimenyetso bibangamiye bigaragara.

Inkuru nziza ni uko ingaruka nyinshi ziba z'agateganyo kandi zikavaho iyo umuti uvuye mu mubiri w'umwana wawe, akenshi mu minsi mike.

Ninde utagomba guhabwa Indomethacin IV?

Indomethacin IV ntikwiriye buri mwana, ndetse n'abafite patent ductus arteriosus. Itsinda ry'abaganga bazasuzuma neza niba ari umutekano ku mwana wawe.

Abana batagomba guhabwa uyu muti barimo abafite ibibazo bikomeye by'impyiko, guhagarara k'umutima cyane, cyangwa kuva amaraso. Uyu muti ntusabwa kandi ku bana bafite ubwoko bumwe bw'indwara zikomeye z'ibihaha.

Imyaka ni ikindi kintu cy'ingenzi. Indomethacin IV ikora neza mu minsi mike ya mbere y'ubuzima kandi igabanya imikorere uko abana bagenda bakura. Abana bavukiye igihe gito cyane cyangwa abafite ibibazo byinshi by'ubuzima bashobora gukenera imiti itandukanye.

Amazina y'ubwoko bwa Indomethacin IV

Indomethacin IV iboneka ku izina ry'ubwoko rya Indocin IV muri Leta Zunze Ubumwe z'Amerika. Iyi ni yo mitegurire ikoreshwa cyane mu bitaro no mu bigo bivura abana bavutse batarageza igihe.

Ibitaro bimwe bishobora gukoresha ubwoko bwa indomethacin IV, burimo ibintu bimwe bikora kandi bikora kimwe n'ubwoko bw'izina. Itsinda ry'abaganga bazakoresha ubwoko buboneka kandi bukwiye ku byo umwana wawe akeneye.

Uburyo bwo gusimbuza Indomethacin IV

Niba indomethacin IV idakwiriye cyangwa idakora ku mwana wawe, hari izindi nzira zishoboka. Umuti w'ibanze usimbura ni ibuprofen IV, ikora kimwe no gufunga ductus arteriosus.

Ibuprofen IV yagaragaje imikorere ingana na indomethacin mu bushakashatsi bwa muganga kandi ishobora gukundwa ku bana bafite ibibazo by'impyiko. Itsinda ryawe ry'abaganga rizaganira ku buryo bwiza bushingiye ku buzima bwihariye bw'umwana wawe.

Niba imiti itagize icyo ikora, gufunga ductus arteriosus mu buryo bw'ubuganga biracyari uburyo bwiza. Iyi nzira, yitwa ligation, ifunga burundu urugingo kandi akenshi isabwa iyo imiti yananiwe cyangwa idakwiriye.

Ese Indomethacin IV iruta Ibuprofen IV?

Indomethacin IV na ibuprofen IV ni imiti ikora neza ku bana bafite patent ductus arteriosus, kandi ubushakashatsi bwerekana ko zikora kimwe. Guhitamo hagati yazo akenshi biterwa n'ubuzima bwihariye bw'umwana wawe.

Indomethacin IV imaze igihe ikoreshwa kandi ifite ubushakashatsi bwinshi buyishyigikiye, bituma iba iya mbere gakondo. Ariko, ibuprofen IV ishobora kuba yoroshye ku mpyiko kandi ishobora gukundwa ku bana bafite ibibazo by'impyiko.

Itsinda ryawe ry'abaganga rizagereranya ibintu nk'imyaka y'umwana wawe, imikorere y'impyiko, n'ubuzima muri rusange mugihe bahitamo hagati yiyi miti. Zombi zifite amateka meza iyo zikoreshejwe neza.

Ibibazo Bikunze Kubazwa Kuri Indomethacin IV

Ese Indomethacin IV irakwiriye ku bana bavukiye igihe kitaragera?

Yego, indomethacin IV yagenewe abana bavukiye igihe kitaragera kandi imaze imyaka myinshi ikoreshwa neza mu bitaro byita ku bana. Uyu muti ukora neza kandi ukaba n'umutekano mwinshi iyo ukoreshejwe mu minsi mike ya mbere y'ubuzima.

Itsinda ryawe ry'abaganga rizagenzura neza imikorere y'impyiko z'umwana wawe, ubuzima bw'umutima, n'ubuzima muri rusange mbere yo gutangira kuvura. Bazanakurikirana hafi mu gihe cyose cyo kuvura kugirango barebe niba umwana wawe ari gusubiza neza.

Nkwiriye gukora iki niba umwana wanjye yagize ingaruka ziterwa na Indomethacin IV?

Nta kintu na kimwe uzakora wowe ubwawe kuko umwana wawe azaba akurikiranwa cyane n'abaganga mu gihe cyose cy'ubuvuzi. Abaganga n'abaforomo bazareba ingaruka zose zishobora kubaho kandi bazahita bitabaza igihe zibayeho.

Niba ubonye impinduka mu myitwarire y'umwana wawe, guhumeka, cyangwa kurya nyuma yo kuvurwa, ntugatinye kubibwira ikipe yawe y'ubuvuzi. Bafite uburambe mu gucunga ingaruka zose kandi bazahindura uburyo bwo kwita ku mwana uko bikwiye.

Biba bite niba Indomethacin IV itagize icyo ikora?

Niba umuti utashoboye gufunga neza umuyoboro wa arterious, ikipe yawe y'ubuvuzi ifite izindi nzira zishobora gukoreshwa. Bashobora kugerageza undi muti wa kabiri cyangwa bagatanga inama yo kubaga.

Kubaga kugira ngo ufunge umuyoboro wa arterious ni uburyo bwashyizweho neza bufite intsinzi nziza. Ikipe yawe y'ubuvuzi izaganira ku nzira nziza zikurikira zishingiye ku miterere y'umwana wawe n'ubuzima bwe muri rusange.

Nzamenya nte niba ubuvuzi bwakoze?

Ikipe yawe y'ubuvuzi izakoresha ishusho ya ultrasound kugira ngo barebe niba umuyoboro wa arterious uzafunga nyuma ya buri dose y'umuti. Iyi igerageza ritagira ububabare ryerekana uko amaraso atembera mu muyoboro kandi rishobora kwemeza niba ubuvuzi bukora.

Ushobora kandi kubona impinduka nziza mu guhumeka k'umwana wawe, kurya, cyangwa urwego rw'imbaraga muri rusange kuko umutima ntugomba gukora cyane. Ikipe yawe y'ubuvuzi izakomeza kukugezaho amakuru ku iterambere ry'umwana wawe mu gihe cyose cy'ubuvuzi.

Ese hariho ingaruka zirambye ziterwa n'ubuvuzi bwa Indomethacin IV?

Abana benshi bakoresha indomethacin IV ntibagira ingaruka zirambye ziterwa n'umuti ubwawo. Ingaruka ziterwa n'impyiko n'izindi ngaruka z'igihe gito zikunda gukira burundu mu minsi mike nyuma yo kurangiza ubuvuzi.

Gufunga neza umuyoboro wa patent ductus arteriosus bifasha mu kwirinda ibibazo by'umutima n'ibihaha byashoboraga kuvuka iyo ubu burwayi butavurwa. Imikorere y'umutima w'umwana wawe igomba gusubira mu buryo busanzwe igihe umuyoboro ufunze neza.