Lacosamide ni iki: Ibyo ikoreshwa, urugero rwo kuyifata, ingaruka zayo, n'ibindi

Lacosamide ni umuti uvura ibibazo byo gufatwa n'indwara yo mu mutwe, abaganga bawutanga banyuzije mu muyoboro wa IV (intravenous) unyura mu maraso yawe. Uyu muti ufasha kugenzura ibibazo byo gufatwa n'indwara yo mu mutwe igihe utabasha gufata imiti unywa mu kanwa, nk'igihe uri mu bitaro cyangwa mu gihe cy'uburwayi bwihutirwa.

Ubwoko bwa IV bukora vuba kugira ngo umuti winjire mu mubiri wawe igihe hakenewe kugenzura ibibazo byo gufatwa n'indwara yo mu mutwe ako kanya. Itsinda ry'abaganga bakwitaho bazagukurikiranira hafi igihe uri gukoresha ubu buvuzi kugira ngo barebe ko bukora neza kandi neza.

Lacosamide ni iki?

Lacosamide ni umuti uvura indwara yo mu mutwe (AED) ubarizwa mu cyiciro gishya cy'imiti ivura ibibazo byo gufatwa n'indwara yo mu mutwe. Ikora mu buryo butandukanye n'imiti ya kera ivura ibibazo byo gufatwa n'indwara yo mu mutwe ikoresha inzira zihariye za sodium mu turemangingo tw'ubwonko bwawe.

Ubwoko bwa intravenous burimo ibintu bikora kimwe n'ibinini bifatwa mu kanwa, ariko byateguwe byihariye kugira ngo bitangwe mu maraso yawe. Ibi bituma umuti ugera mu bwonko bwawe vuba kurusha ibinini, ibi bikaba by'ingenzi cyane mu gihe cy'ibibazo byo gufatwa n'indwara yo mu mutwe byihutirwa.

Abaganga basanzwe bakoresha IV lacosamide igihe uri mu bitaro kandi ukeneye kugenzura ibibazo byo gufatwa n'indwara yo mu mutwe ako kanya. Ifatwa nk'umuti uvura ibibazo byo gufatwa n'indwara yo mu mutwe ukomeye ku rugero ruciriritse ushobora kugira akamaro kanini ku bwoko bumwe bw'ibibazo byo gufatwa n'indwara yo mu mutwe.

Lacosamide ikoreshwa mu kuvura iki?

IV lacosamide ikoreshwa cyane cyane mu kuvura ibibazo byo gufatwa n'indwara yo mu mutwe bitangirira ahantu hamwe (bita kandi ibibazo byo gufatwa n'indwara yo mu mutwe by'ibanze) ku bantu bakuru n'abana bafite imyaka 17 n'abarenze. Ibi bibazo bitangirira ahantu hamwe mu bwonko bwawe kandi bishobora kwimukira mu bindi bice.

Umuti wawe ashobora guhitamo ubwoko bwa IV igihe udashobora kumira ibinini bitewe n'uburwayi, kubagwa, cyangwa ibibazo bikomeje byo gufatwa n'indwara yo mu mutwe. Ikoreshwa kandi igihe ukeneye guhindura imiti yo mu kanwa ukajya mu buvuzi bwa IV mu gihe ukomeza urugero rwawo mu mubiri wawe.

Rimwe na rimwe abaganga bakoresha lacosamide ya IV nk'umuti wongerwa ku yindi miti ivura ibibazo byo mu mutwe iyo umuti umwe gusa udashobora kugenzura neza ibibazo byawe. Ubu buryo bwo guhuza imiti bushobora gufasha kugenzura neza ibibazo byo mu mutwe mu gihe bishobora kugabanya ingaruka ziterwa n'imiti.

Lacosamide ikora ite?

Lacosamide ikora igira ingaruka ku miyoboro ya sodium mu turandaryi twawe two mu bwonko, nk'uko imiryango mito igenzura imikorere y'amashanyarazi. Iyo iyi miyoboro idakora neza, ishobora gutera ibibazo byo mu mutwe.

Uyu muti ufasha guhagarika iyi miyoboro, bigatuma bigorana ko imikorere idasanzwe y'amashanyarazi ikwirakwira mu bwonko bwawe. Tekereza nk'uko bifasha gutuza uturandaryi two mu bwonko twashyutswe cyane bishobora gutera ibibazo byo mu mutwe.

Uyu ni umuti uvura ibibazo byo mu mutwe ukomeye, akenshi utangira gukora mu minota 30 kugeza ku masaha 2 iyo utanzwe mu maraso. Uburyo bwa IV butuma urugero rw'umuti mu maraso ruhuza, ibi ni ngombwa mu gukumira ibibazo byo mu mutwe.

Nkwiriye gufata lacosamide nte?

Ntabwo uzifata lacosamide ya IV wenyine - itsinda ryawe ry'ubuzima rizayikoresha binyuze mu muyoboro wa IV mu kuboko kwawe cyangwa ukuboko. Uyu muti utangwa nk'uruvange rutinda mu minota 30 kugeza kuri 60.

Umuforomo wawe azakugenzura neza mugihe cyo kuvanga no mumasaha menshi nyuma yaho. Bazareba ibimenyetso byose by'ingaruka ziterwa n'imiti cyangwa ibimenyetso byo kwanga umuti, kandi barebe umuvuduko w'umutima wawe kuko lacosamide ishobora kugira ingaruka ku mikorere y'umutima.

Ntabwo ukeneye guhangayika kubyerekeye imikoranire y'ibiryo n'uburyo bwa IV kuko bigera mu maraso yawe. Ariko, menyesha itsinda ryawe ry'ubuzima ku miti yose cyangwa ibyongerera imiti urimo gufata, kuko ibi bishobora kugirana imikoranire na lacosamide.

Umuvuduko wo kuvanga n'urugero rwose ruzabarwa neza hashingiwe ku kigereranyo cyawe, uburwayi bwawe, n'uburyo wabyakiriye. Ntukagerageze guhindura umuvuduko wa IV wenyine - burigihe ubaze umuforomo wawe niba ufite impungenge.

Nkwiriye gufata lacosamide igihe kingana iki?

Ubukure bw'imiti ya lacosamide yinjizwa mu urugingo biterwa n'uburwayi bwawe bwihariye n'uburyo umubiri wawe wemera imiti. Abantu bamwe bayihabwa iminsi mike gusa, mu gihe abandi bashobora kuyihabwa ibyumweru byinshi.

Muganga wawe azagusimbuza imiti ya lacosamide yo kunywa mu kanwa igihe uzaba ushobora kongera kumira imiti. Ibi bifasha kugumisha urugero rw'imiti mu mubiri wawe idahagaze.

Mu kugenzura ibibazo byo gufatwa n'indwara mu gihe kirekire, ushobora gukomeza kunywa lacosamide mu buryo bw'ibinini mu mezi cyangwa imyaka. Muganga wawe azagenzura gahunda yawe yo kuvurwa buri gihe kandi ashobora guhindura imiti yawe bitewe n'uburyo ibibazo byo gufatwa n'indwara bigenzurwa n'ingaruka zose zikubaho.

Ntuzigere uhagarika kunywa lacosamide ako kanya, yaba iyo yinjizwa mu urugingo cyangwa iyo unywa, kuko ibi bishobora gutera ibibazo byo gufatwa n'indwara bikomeye. Muganga wawe azagutegurira gahunda yo kugabanya buhoro buhoro imiti niba ukeneye kuyihagarika.

Ni izihe ngaruka ziterwa na Lacosamide?

Kimwe n'imiti yose, lacosamide yinjizwa mu urugingo ishobora gutera ingaruka, nubwo atari buri wese uzazibona. Ingaruka zisanzwe zikunda kuba zoroshye kandi akenshi zigenda zikemuka umubiri wawe umaze kumenyera imiti.

Dore ingaruka zisanzwe zivugwa cyane ushobora guhura nazo:

• Kuribwa umutwe cyangwa kumva utameze neza
• Kuribwa umutwe
• Isesemi cyangwa kuruka
• Kureba ibintu bibiri cyangwa guhumirwa
• Kunanirwa cyangwa gusinzira
• Ibibazo byo guhuza ibice by'umubiri
• Kuzunguzwa cyangwa guhinda umushyitsi

Izi ngaruka zisanzwe zikunda kubaho mu minsi mike ya mbere yo kuvurwa kandi akenshi zigenda zigabanuka umubiri wawe umaze kumenyera imiti. Itsinda ryawe ry'ubuvuzi rizakugenzura neza kandi rishobora guhindura uburyo uvurwa niba bibaye ngombwa.

Hariho kandi n'izindi ngaruka zitavugwa cyane ariko zikomeye zisaba ubufasha bwihuse bw'abaganga:

• Imbura ry'umutima (umutima utera nabi)
• Uburwayi bukomeye bwo kwanga imiti (uruhu rurashya, kubyimba, guhumeka bigoye)
• Impinduka mu myumvire cyangwa gutekereza kwikomeretsa
• Kuribwa cyane umutwe cyangwa kugwa igihumure
• Gusohoka amaraso cyangwa gukomereka bidasanzwe
• Ibimenyetso by'ibibazo by'umwijima (uruhu cyangwa amaso y'umuhondo)

Itsinda ryawe ry'abaganga rizakomeza gukurikirana imikorere y'umutima wawe n'ibindi bimenyetso by'ingenzi mugihe uri guhabwa lacosamide ya IV. Niba ubonye ibimenyetso bibangamiye, ntugatinye guhamagara umuforomo wawe ako kanya.

Ninde utagomba gufata Lacosamide?

Abantu bamwe ntibagomba guhabwa lacosamide ya IV kubera ibyago byiyongereye by'ingorane zikomeye. Muganga wawe azasuzuma neza amateka yawe y'ubuvuzi mbere yo gutegeka uyu muti.

Ntugomba guhabwa lacosamide niba ufite allergie izwi kuri uyu muti cyangwa ibintu byawo byose. Ibimenyetso byo kwanga umuti birimo uruhu rurashya, kubyimba, guhumeka bigoye, cyangwa kuribwa cyane umutwe.

Abantu bafite indwara zimwe na zimwe z'umutima bakeneye kwitabwaho by'umwihariko, kuko lacosamide ishobora kugira ingaruka kumikorere y'umutima. Muganga wawe azitonda cyane niba ufite:

• Indwara zo gutera k'umutima (arrhythmias)
• Gufunga umutima cyangwa izindi ngorane zo kuyobora
• Indwara ikomeye y'umutima
• Amateka yo kugwa igihumure

Itsinda ryawe ry'ubuzima rizakora electrocardiogram (EKG) mbere yo gutangira kuvurwa no gukurikirana imikorere y'umutima wawe mugihe cyose cyo guterwa urushinge. Ibi bifasha kumenya niba umutima wawe wihanganira umuti neza.

Kwitonda by'umwihariko birakenewe kandi kubantu bafite ibibazo by'impyiko cyangwa umwijima, kuko izi ngingo zifasha gutunganya umuti. Muganga wawe ashobora gukenera guhindura urugero rwawe cyangwa kugukurikiranira hafi niba ufite izi ngorane.

Amazina y'ubwoko bwa Lacosamide

Izina ry'ubwoko bwa lacosamide ni Vimpat, iboneka mumitangire yombi ya IV n'umunwa. Iri nicyo kimenyetso gikoreshwa cyane muri Leta Zunze Ubumwe z'Amerika no mubindi bihugu byinshi.

Imiti ya lacosamide igurishwa ku izina rusange iraboneka kandi irimo umuti umwe ukora nk'uw'izina ry'uruganda. Muganga wawe cyangwa umufarimasi akora agufasha gusobanukirwa uwo uri guhabwa.

Uko wakwakira lacosamide y'izina ry'uruganda cyangwa iy'izina rusange, umuti ukora kimwe kandi ufite ubushobozi bungana. Guhitamo akenshi biterwa n'ubwishingizi bwawe n'ibyo ivuriro ryemera.

Izindi miti isimbura Lacosamide

Hariho indi miti myinshi ivurwa mu nshinge ivura ibibazo byo mu bwonko niba lacosamide itagukwiriye. Muganga wawe azahitamo indi miti ikwiriye bitewe n'ubwoko bw'ibibazo byo mu bwonko ufite n'uburwayi ufite.

Izindi miti isanzwe ikoreshwa mu nshinge harimo phenytoin (Dilantin), levetiracetam (Keppra), na aside ya valproic (Depacon). Buri muti muri iyi ikora mu buryo butandukanye kandi ifite inyungu zayo n'ingaruka zishobora guterwa.

Ku bantu bamwe, guhuza imiti bikora neza kurusha umuti umwe. Muganga wawe ashobora kugusaba kongeraho cyangwa guhindura umuti utandukanye niba ibibazo byo mu bwonko byawe bitavurwa neza na lacosamide yonyine.

Guahitamo indi miti biterwa n'ibintu nk'imyaka yawe, izindi ndwara, imiti ishobora gufatanya, n'uburyo wabyitwayemo ku miti yindi y'ibibazo byo mu bwonko mu gihe cyashize.

Ese Lacosamide iruta Levetiracetam?

Lacosamide na levetiracetam (Keppra) ni imiti ivura neza ibibazo byo mu bwonko, ariko ikora mu buryo butandukanye kandi ishobora gukwira abantu batandukanye. Nta na rimwe riruta irindi.

Lacosamide ikunda gutera ingaruka nke zijyanye n'imitekerereze ugereranyije na levetiracetam, rimwe na rimwe ishobora gutera umujinya cyangwa guhinduka kw'imitekerereze. Ariko, lacosamide ifite ingaruka nyinshi zishobora gutera ku mutima zisaba gukurikiranwa.

Levetiracetam akenshi ikundwa ku bantu bafite indwara z'umutima kuko ntigira ingaruka ku mutima. Yemerewe kandi gukoreshwa ku bwoko bwinshi bw'ibibazo byo mu bwonko no mu byiciro by'imyaka bitandukanye kurusha lacosamide.

Muganga wawe azatekereza ku bwoko bw'ibitero byawe, amateka yawe y'ubuvuzi, imiti yindi ufata, n'ingaruka zishobora kubaho mugihe ahitamo hagati y'izi nzira. Igitera neza gishobora gutandukana cyane ku muntu ku muntu.

Ibibazo Bikunze Kubazwa Kuri Lacosamide

Q1. Ese Lacosamide iratekanye ku barwayi b'umutima?

Lacosamide isaba kwitonda cyane kubantu bafite indwara z'umutima kuko ishobora kugira ingaruka kumuvuduko w'umutima. Muganga wawe azakora EKG mbere yo gutangira kuvura kandi azakurikiranira hafi umutima wawe mugihe cyo guterwa urwo rukingo.

Niba ufite indwara y'umutima yoroheje, urashobora gukomeza guhabwa lacosamide hamwe no gukurikiranwa neza. Ariko, abantu bafite ibibazo bikomeye by'umuvuduko w'umutima cyangwa guhagarara k'umutima bashobora gukenera imiti yindi.

Itsinda ryawe ry'ubuzima rizakomeza gukurikiranira hafi umuvuduko w'umutima wawe n'umuvuduko w'amaraso mugihe ukiri guterwa IV lacosamide. Bazahagarika guterwa urwo rukingo ako kanya niba hari impinduka zidasanzwe zigaragara kumuvuduko w'umutima zibaye.

Q2. Nkwiriye gukora iki niba mbonye lacosamide nyinshi bitunguranye?

Kubera ko IV lacosamide itangwa nabaganga, gukabya imiti bitunguranye ntibishoboka cyane. Itsinda ryawe ry'ubuvuzi ribara neza kandi rikagenzura buri dose uhabwa.

Niba gukabya imiti byabaho, ibimenyetso bishobora kuba harimo isereri rikomeye, ibibazo byo guhuza ibice by'umubiri, cyangwa impinduka zumuvuduko w'umutima. Itsinda ryawe ry'ubuvuzi ryahita rihagarika guterwa urwo rukingo kandi rigatanga ubufasha.

Nta muti wihariye wo gukabya lacosamide, ariko itsinda ryawe ry'ubuvuzi rishobora kuvura ibimenyetso no gushyigikira imikorere yumubiri wawe kugeza igihe umuti uva mumubiri wawe.

Q3. Nkwiriye gukora iki niba nciwe dose ya lacosamide?

Kubera ko IV lacosamide itangwa mumavuriro nabaganga, ntuzacikanwa na dose muburyo busanzwe. Itsinda ryawe ry'ubuvuzi rikoresha gahunda ikarishye kugirango rishobore kuguha imiti yawe mugihe cyiza.

Niba hari gutinda ku doze yawe yateganyijwe kubera ibikorwa byo kwa muganga cyangwa izindi mvura, ikipe yawe y'ubuzima izahindura igihe bikwiye. Bazakora uko bashoboye kugirango ugumane urugero rwa imiti ruhagije kugirango wirinde ibitero by'indwara.

Niba umaze guhindukira ukajya kunywa lacosamide yo mu kanwa uri mu rugo, muganga wawe azaguha amabwiriza yihariye yo gukora niba wibagiwe gufata doze ya tablet.

Q4. Ni ryari nshobora kureka gufata Lacosamide?

Umwanzuro wo kureka lacosamide ugomba gufatwa buri gihe hamwe n'ubuyobozi bwa muganga wawe. Ntukigere ureka gufata iyi miti mu buryo butunguranye, kuko ibi bishobora gutera ibitero by'indwara by'akaga, kabone n'iyo umaze amezi atarimo ibitero.

Muganga wawe akenshi azategereza kugeza umaze imyaka nibura ibiri utarimo ibitero mbere yo gutekereza kureka gukoresha imiti. Ubu buryo bukubiyemo kugabanya buhoro buhoro doze yawe mu byumweru byinshi cyangwa amezi.

Abantu bamwe bakeneye gufata imiti irwanya ibitero by'indwara ubuzima bwabo bwose kugirango birinde ko ibitero by'indwara bisubira. Muganga wawe azagufasha gusobanukirwa uko ubuzima bwawe bwite buteye n'umugambi mwiza wo kugenzura ibitero by'indwara.

Q5. Nshobora gutwara imodoka nkanwa Lacosamide?

Imipaka yo gutwara imodoka iterwa n'uko ibitero by'indwara byawe bigenda n'amategeko yaho, ntabwo biterwa no kunywa lacosamide gusa. Ibihugu byinshi bifite ibisabwa byihariye ku bijyanye n'igihe ugomba kumara utarimo ibitero mbere yo gutwara imodoka.

Lacosamide ishobora gutera isereri n'ibibazo byo guhuza ibintu, cyane cyane iyo utangiye kuyifata. Ibi bibazo bishobora kugira ingaruka ku bushobozi bwawe bwo gutwara imodoka neza, kabone n'iyo utarimo ibitero.

Ganira ku mutekano wo gutwara imodoka na muganga wawe, ushobora kugufasha gusobanukirwa igihe bitewe gutwara imodoka bitewe n'uko ibitero byawe bigenda, ingaruka z'imiti, n'amategeko yaho. Umutekano wawe n'umutekano w'abandi bari mu muhanda ugomba guhora ari wo w'imbere.