Lacosamide ni iki: Ibikoresho, Uburyo bwo Gukoresha, Ingaruka ziterwa n'iyo miti n'ibindi

Lacosamide ni umuti wandikirwa n'abaganga ukoreshwa cyane mu kugenzura ibibazo by'imitsi mu bantu barwaye indwara y'igicuri. Uyu muti ubarirwa mu cyiciro cy'imiti yitwa anticonvulsants cyangwa imiti igabanya ibibazo by'imitsi, ikora mu guhagarika imikorere y'amashanyarazi mu bwonko bwawe kugira ngo birinde ko ibibazo by'imitsi bibaho.

Uyu muti wabaye uburyo bw'ingenzi bwo kuvura abantu benshi barwaye indwara y'igicuri kuva wemezwa na FDA. Kumva uko ikora, igihe yandikirwa, n'icyo wakwitega bishobora kugufasha kumva ufite icyizere cyinshi ku rugendo rwawe rwo kuvurwa.

Lacosamide ni iki?

Lacosamide ni umuti ugabanya ibibazo by'imitsi ufasha kwirinda ibibazo by'imitsi by'igicuri binyuze mu kugira ingaruka ku miyoboro ya sodium mu bwonko bwawe. Tekereza kuri iyi miyoboro nk'inzira nto zigenzura ibimenyetso by'amashanyarazi hagati y'uturemangingo tw'ubwonko.

Iyo ibi bimenyetso by'amashanyarazi bibayeho mu buryo butunganye cyangwa burenze urugero, ibibazo by'imitsi birashobora kubaho. Lacosamide ikora mu gutuza buhoro ibi bimenyetso by'amashanyarazi bikabije, bifasha kugarura imikorere y'ubwonko iringaniye. Ibi bituma bitaba ngombwa ko ibibazo by'imitsi bitangira cyangwa bikwirakwira.

Uyu muti ufashwe nk'umuti wo mu gisekuru gishya ugabanya ibibazo by'imitsi, akenshi bivuze ko ushobora kugira ingaruka nkeya ku yindi miti ugereranije n'imiti ishaje igabanya ibibazo by'imitsi. Muganga wawe azemeza niba uyu muti ukwiriye kubera uko ubuzima bwawe buhagaze.

Lacosamide ikoreshwa mu iki?

Lacosamide yandikirwa cyane kuvura ibibazo by'imitsi bitangirira mu gice kimwe cy'ubwonko mu bantu bakuru n'abana bafite imyaka 4 n'abarenze. Ibi ni ibibazo by'imitsi bitangirira mu gace kamwe k'ubwonko kandi bishobora gukwirakwira cyangwa ntibikwirakwire mu tundi duce.

Muganga wawe ashobora kukwandikira lacosamide mu buryo bubiri bukuru. Icya mbere, irashobora gukoreshwa hamwe n'indi miti igabanya ibibazo by'imitsi iyo uburyo bwawe bwo kuvurwa butagikora neza mu kugenzura ibibazo by'imitsi. Icya kabiri, mu bihe bimwe na bimwe, irashobora kwandikwa nk'umuti umwe wo kugenzura ibibazo by'imitsi.

Uyu muti ufasha cyane abantu bagira ibibazo byo gufatwa n'indwara y'igicuri yitwa focal seizures, izwi kandi nka partial seizures. Izi seizures zishobora gutera ibimenyetso nk'imigendekere idasanzwe, kumva ibintu bidasanzwe, cyangwa guhinduka mu bwenge, bitewe n'igice cy'ubwonko bwawe cyagizweho ingaruka.

Lacosamide ikora ite?

Lacosamide ikora yibanda ku tuyunguruzo twihariye twa sodium mu turemangingo tw'ubwonko bwawe. Utu tuyunguruzo tumeze nk'imiryango igenzura igihe ibimenyetso by'amashanyarazi bishobora kunyura hagati y'uturemangingo tw'ubwonko.

Iyo seizures zibaye, uturemangingo tw'ubwonko akenshi twohereza ibimenyetso by'amashanyarazi vuba cyangwa mu buryo budasanzwe. Lacosamide ifasha kugabanya iyi mirimo y'amashanyarazi y'umurengera ikora ku buryo utu tuyunguruzo twa sodium dukora. Ibi bituma habaho ibidukikije by'amashanyarazi bihamye mu bwonko bwawe.

Uyu muti ufashwe nk'ufite imbaraga ziringaniye mu miti irwanya indwara y'igicuri. Birahagije kugenzura seizures ku bantu benshi, ariko muri rusange byihanganirwa neza iyo bikoreshejwe nk'uko byategetswe n'umuganga wawe.

Nkwiriye gufata Lacosamide nte?

Fata lacosamide nk'uko umuganga wawe abitegeka, akenshi kabiri ku munsi hamwe cyangwa hatariho ibiryo. Urashobora kuyifata n'amazi, amata, cyangwa umutobe ukurikije icyo ukunda, kuko ibiryo ntacyo bihindura ku buryo umubiri wawe winjiza uyu muti.

Niba ufite igifu cyoroshye, gufata lacosamide hamwe n'ibiryo cyangwa amata birashobora gufasha kugabanya ibibazo byose byo mu gifu. Gerageza gufata imiti yawe ku masaha amwe buri munsi kugirango ugumane urwego rwawo ruzigama mu mubiri wawe.

Mimina ibinini byose aho kubisya, kubihekenya, cyangwa kubica. Niba ufata uburyo bw'amazi, koresha igikoresho cyo gupima cyatanzwe na farumasi yawe kugirango wemeze ko upima neza. Ntukoreshe ibiyiko byo mu rugo, kuko bishobora kutatanga urugero rukwiye.

Nkwiriye gufata Lacosamide igihe kingana iki?

Lacosamide akenshi ni umuti ukoreshwa igihe kirekire mu kuvura indwara y'igicuri, kandi abantu benshi bagomba kuwufata imyaka myinshi cyangwa se ndetse mu buzima bwabo bwose. Igihe umuti umara gukoreshwa biterwa n'uburyo umubiri wawe wakiriye umuti ndetse n'uburyo indwara y'igicuri yigaragaza.

Muganga wawe azajya akurikirana uko urimo witwara kandi ashobora guhindura uburyo uvurwa uko igihe kigenda gihita. Abantu bamwe babasha kugenzura neza indwara y'igicuri bakomeza gufata umuti igihe cyose, mu gihe abandi bashobora kuza guhindurirwa imiti itandukanye.

Ntuzigere uhagarika gufata lacosamide mu buryo butunguranye, kabone n'iyo wumva umeze neza cyangwa utarigeze ugira ibimenyetso by'indwara y'igicuri mu gihe gishize. Guhagarika imiti ivura indwara y'igicuri mu buryo butunguranye bishobora gutera ibimenyetso by'indwara y'igicuri cyangwa se ndetse n'indwara ikomeye yitwa status epilepticus. Muganga wawe azagufasha mu guhindura uburyo ufata imiti yawe.

Ni Ibihe Bimenyetso Bigaragara Byatewe na Lacosamide?

Kimwe n'indi miti yose, lacosamide ishobora gutera ibimenyetso, nubwo atari buri wese ubyumva. Ibimenyetso byinshi ni bike cyangwa se biringaniye kandi akenshi biragenda bikira uko umubiri wawe wimenyereza umuti.

Ibimenyetso bisanzwe abantu benshi bagira harimo isereri, kubabara umutwe, isesemi, no kubona ibintu bibiri. Ibi bimenyetso akenshi biragaragara cyane iyo utangiye gufata umuti cyangwa se iyo doze yawe yongerewe.

Dore ibimenyetso byinshi bikunze kugaragara ushobora guhura nabyo:

• Isereri cyangwa kumva utameze neza
• Kubabara umutwe
• Isesemi cyangwa kuribwa mu nda
• Kubona ibintu bibiri cyangwa guhumirwa
• Umunaniro cyangwa gusinzira
• Ibibazo byo guhuza ibice by'umubiri
• Umuriro cyangwa guhinda umushyitsi

Ibi bimenyetso bisanzwe akenshi bigenda bigabanuka uko umubiri wawe umenyera umuti, akenshi mu byumweru bike umaze gutangira kuvurwa cyangwa se umaze guhindurirwa doze.

Ibimenyetso bikomeye bishobora kubaho, nubwo bitajya bibaho kenshi. Ibi bisaba ubufasha bwihuse bw'abaganga kandi ntibagomba kwirengagizwa.

Vugana na muganga wawe ako kanya niba ubonye ibi bimenyetso bikurikira:

• Kuribwa cyane cyangwa kugwa igihumure
• Umutima utera nabi cyangwa kuribwa mu gituza
• Impinduka zikomeye mu myumvire cyangwa ibitekerezo byo kwiyahura
• Uruhu rurwara cyane cyangwa amabara
• Kubura umwuka cyangwa kubura kumeza
• Ibibazo bikomeye byo guhuza ibice by'umubiri cyangwa kugwa

Ingaruka zidakunze kubaho ariko zikomeye zirimo ibibazo by'umutima n'uburwayi bukomeye bwo mu mubiri. Nubwo ibi bidakunze kubaho, ni ngombwa kubimenya kandi ugahita ushaka ubufasha bw'abaganga niba bibayeho.

Ninde utagomba gufata Lacosamide?

Lacosamide ntikwiriye kuri buri wese, kandi ibibazo by'ubuzima runaka cyangwa ibihe bishobora gutuma bitakwiriye kuri wowe. Muganga wawe azasuzuma neza amateka yawe y'ubuzima mbere yo kugushyiriraho uyu muti.

Abantu bafite ibibazo by'umutima runaka bagomba gukoresha lacosamide bafite ubwitonzi bwinshi. Niba ufite ibibazo by'umutima, umutima uhagarara, cyangwa indwara ikomeye y'umutima, muganga wawe ashobora gukenera kugukurikiranira hafi cyangwa agatekereza ku zindi nshuti.

Ukwiye kumenyesha muganga wawe niba ufite kimwe muri ibi bikurikira mbere yo gutangira gufata lacosamide:

• Uburwayi bw'umutima cyangwa umutima uhagarara
• Indwara ikomeye y'umutima
• Indwara y'impyiko cyangwa imikorere y'impyiko igabanuka
• Indwara y'umwijima
• Amateka yo kwiheba cyangwa ibitekerezo byo kwiyahura
• Allergie kuri lacosamide cyangwa imiti isa nayo

Ibitekerezo byihariye bikoreshwa ku bagore batwite kandi bonka, kuko umutekano wa lacosamide mugihe cyo gutwita utarashyirwaho neza. Muganga wawe azagereranya inyungu n'ibibazo niba uteganya gutwita cyangwa umaze gutwita.

Amazina y'ubwoko bwa Lacosamide

Lacosamide iboneka munsi y'izina ry'ubwoko rya Vimpat, ikorwa na UCB Pharma. Iyi ni verisiyo y'ubwoko bw'umuti isanzwe itangwa cyane.

Imiti ya lacosamide ikorwa mu buryo rusange iraboneka kandi irimo ibintu bikora kimwe nk'izina ry'ubwoko. Imiti ikorwa mu buryo rusange ikorerwa igeragezwa rikomeye kugira ngo hemeze ko ikora kimwe nk'imiti y'izina ry'ubwoko.

Farumasi yawe ishobora gusimbuza lacosamide ikorwa mu buryo rusange aho gukoresha izina ry'ubwoko keretse muganga wawe asabye by'umwihariko izina ry'ubwoko. Uburyo bwombi bufite akamaro kamwe mu kuvura ibibazo byo gufatwa iyo bikoreshwa nk'uko byategetswe.

Uburyo bwo gusimbuza Lacosamide

Imiti myinshi ivura ibibazo byo gufatwa irashobora gukoreshwa nk'uburyo bwo gusimbuza lacosamide, bitewe n'ubwoko bw'ibibazo byo gufatwa ufite n'ubuzima bwawe. Muganga wawe azagufasha kumenya uburyo bwiza kuri wowe.

Uburyo busanzwe bwo gusimbuza burimo levetiracetam, lamotrigine, na oxcarbazepine. Buri muti muri iyi miti ukora mu buryo butandukanye gato kandi ushobora kugira ingaruka zitandukanye, izo muganga wawe azatekereza igihe afata icyemezo cyo kuvura.

Guhitamo uburyo bwo gusimbuza biterwa n'ibintu nk'ubwoko bw'ibibazo byo gufatwa ufite, indi miti urimo gufata, ingaruka zishobora guterwa, n'uburyo wowe ubwawe witwara ku miti. Rimwe na rimwe, guhuza imiti bikora neza kurusha imiti imwe mu kugenzura ibibazo byo gufatwa.

Ese Lacosamide iruta Levetiracetam?

Lacosamide na levetiracetam ni imiti ivura ibibazo byo gufatwa ifite akamaro, ariko nta n'imwe iruta iyindi. Guhitamo neza biterwa n'uko ubuzima bwawe bumeze, ubwoko bw'ibibazo byo gufatwa ufite, n'uburyo witwara kuri buri muti.

Lacosamide ishobora gutera ingaruka nke zijyanye n'amarangamutima ugereranyije na levetiracetam, rimwe na rimwe ishobora gutera umujinya cyangwa impinduka z'amarangamutima ku bantu bamwe. Ariko, lacosamide ishobora gutera kuruka cyangwa ibibazo byo guhuza ibice by'umubiri.

Umuvuzi wawe azatekereza ku bintu nk'uburyo ibyago byawe bigenda, izindi ndwara ufite, imiti urimo gufata, n'ingaruka zishobora kubaho mugihe ahitamo hagati y'ibi byemezo. Abantu bamwe babaho neza bafata umuti umwe, mugihe abandi bageraho ibisubizo byiza bafata undi.

Ibibazo Bikunze Kubazwa Kuri Lacosamide

Ese Lacosamide irakwiriye abantu barwaye indwara z'umutima?

Lacosamide isaba gukurikiranwa neza kubantu barwaye indwara z'umutima, cyane cyane abafite ibibazo by'umutima cyangwa guhagarara k'umutima. Uyu muti ushobora kugira ingaruka kumutima, bityo umuganga wawe ashobora gutuma ukorerwa ibizamini by'umutima mbere na mugihe cy'imiti.

Niba urwaye indwara y'umutima, umuganga wawe azagereranya inyungu zo kugenzura ibyago byawe n'ibishobora guteza ibibazo by'umutima. Barashobora gutangira bakuguha urugero ruto hanyuma bagakurikirana imikorere y'umutima wawe neza mugihe cyose uvurwa.

Nigute nzakora niba mfashwe n'umuti wa Lacosamide mwinshi?

Niba ufashwe n'umuti wa lacosamide mwinshi kuruta uko byategetswe, vugana n'umuganga wawe cyangwa ikigo gishinzwe imiti ihumanya ako kanya. Ntukategere ibimenyetso, kuko gufata icyemezo vuba bifite akamaro k'umutekano wawe.

Ibimenyetso byo kurenza urugero rwawo bishobora kuba birimo isereri rikomeye, ibibazo byo guhuza ibice by'umubiri, cyangwa impinduka mumikorere y'umutima. Niba ufite ibimenyetso bikomeye, shaka ubufasha bwihutirwa bw'ubuvuzi ako kanya aho gutegereza kuvugana n'umuganga wawe usanzwe.

Nigute nzakora niba nirengagije gufata urugero rwa Lacosamide?

Niba wibagiwe gufata urugero rwa lacosamide, jya urufata uko wibuka, keretse igihe cyo gufata urugero rukurikira kigeze. Muricyo gihe, reka urugero wibagiwe hanyuma ukomeze gahunda yawe isanzwe yo gufata imiti.

Ntuzigere wongera urugero rwawo kugirango wuzuze urwo wibagiwe, kuko ibyo bishobora kongera ibyago byo kugira ingaruka ziterwa n'umuti. Niba ukunda kwibagirwa urugero rwawo, tekereza gukoresha igikoresho cyo gutegura imiti cyangwa gushyiraho ibyibutsa kuri terefone yawe kugirango bigufashe kuguma ku murongo.

Nshobora guhagarika ryari gufata Lacosamide?

Ugomba guhagarika gufata lacosamide ari uko muganga wawe abigufashije, kabone n'iyo umaze igihe kirekire udafite ibibazo byo gufatwa. Muganga wawe azasuzuma uko urwaye, ubuzima bwawe muri rusange, n'ibindi bintu mbere yo kugira impinduka ku buryo uvurwa.

Niba muganga wawe asanze bikwiye guhagarika lacosamide, bazashyiraho gahunda yo kugabanya buhoro buhoro urugero rwawe mu byumweru byinshi cyangwa amezi. Ibi bifasha kwirinda gufatwa bishobora kubaho iyo imiti igabanya gufatwa ihagaritswe vuba cyane.

Nshobora kunywa inzoga nkanwa lacosamide?

Inzoga irashobora kongera ingaruka zo gutuza za lacosamide kandi irashobora gutuma ingaruka nk'izunguruka n'ibibazo byo guhuza bigenda birushaho. Muri rusange ni byiza kugabanya cyangwa kwirinda inzoga mugihe ufata uyu muti.

Niba uhisemo kunywa inzoga, bikore mu rugero ruto kandi witondere cyane ibikorwa bisaba guhuza cyangwa gukanguka. Buri gihe ganira ku ikoreshwa ry'inzoga na muganga wawe, kuko bashobora gutanga ubujyanama bwihariye bushingiye ku miterere yawe n'indi miti ushobora kuba ufata.