Laronidase (inzira y'imijyana myinshi)

Aldurazyme

Laronidase ikoreshwa mu kuvura indwara ya mucopolysaccharidosis (MPS I) y'ubwoko bwa Hurler na Hurler-Scheie, iterwa no kubura enzyme runaka yitwa α-L-iduronidase mu mubiri. Laronidase iboneka gusa ku rupapuro rw'umuganga. Iyi miti iboneka mu buryo bukurikira bwo kuyipima:

Mu gufata icyemezo cyo gukoresha imiti, ibyago byo gufata iyo miti bigomba guhanurwa n'akamaro izagira. Iki ni icyemezo wowe na muganga wawe muzafatanya gufata. Kuri iyi miti, ibi bikurikira bigomba kwitabwaho: Bwira muganga wawe niba wigeze ugira uburwayi butasanzwe cyangwa imitego y'ubuziranenge kuri iyi miti cyangwa izindi miti. Nanone, bwira umuhanga mu by'ubuzima ufite izindi mico y'ubuziranenge, nko ku biribwa, amabara, ibintu birinda kwangirika, cyangwa inyamaswa. Ku bicuruzwa bitagomba kwandikwa, soma witonze ibikoresho biri ku gipfunyika cyangwa ku kimenyetso. Ubushakashatsi bukwiye ntabwo bwakozwe ku isano iri hagati y'imyaka n'ingaruka za laronidase ku bana bari munsi y'imyaka 5. Ubuziranenge n'ingaruka ntabwo byarangiye. Ubushakashatsi bukwiye ku isano iri hagati y'imyaka n'ingaruka za laronidase ntabwo bwakozwe ku bantu bakuze. Nta bushakashatsi buhagije ku bagore bwo kumenya ibyago by'uruhinja mu gihe bakoresha iyi miti mu gihe cyo konsa. Pima inyungu zishoboka ugereranije n'ibyago bishoboka mbere yo gufata iyi miti mu gihe cyo konsa. Nubwo imiti imwe n'imwe idakwiye gukoreshwa hamwe na gato, mu bindi bihe imiti ibiri itandukanye ishobora gukoreshwa hamwe nubwo hariho isano ishobora kubaho. Muri uru rubanza, muganga wawe ashobora kwifuza guhindura umwanya, cyangwa izindi ngamba zishobora kuba ngombwa. Bwira umuhanga mu by'ubuzima ufite indi miti yanditswe cyangwa idasabwa (over-the-counter [OTC]). Imiti imwe n'imwe ntikwiye gukoreshwa mu gihe cyo kurya cyangwa hafi yacyo cyangwa kurya imirire imwe n'imwe kuko isano ishobora kubaho. Gukoresha inzoga cyangwa itabi hamwe n'imiti imwe nabyo bishobora gutera isano kubaho. Gabagana n'umuhanga mu by'ubuzima wawe gukoresha imiti yawe hamwe n'ibiribwa, inzoga, cyangwa itabi. Kuba hari ibindi bibazo by'ubuzima bishobora kugira ingaruka ku ikoreshwa ry'iyi miti. Menya neza kubwira muganga wawe niba ufite ibindi bibazo by'ubuzima, cyane cyane: