Levothyroxine ni iki: Ibyo ikoreshwa, urugero rwo gufata, ingaruka zayo n'ibindi

Levothyroxine ni umusemburo wa thyroïde ukorwa mu buryo bwa gihanga usimbura cyangwa wongera umusemburo wa kamere umubiri wawe ukora. Niba thyroïde yawe idakora umusemburo uhagije ku giti cyawe, levothyroxine irinjira kugira ngo ifashe umubiri wawe kugumana imikorere isanzwe, urwego rw'imbaraga, n'ubuzima muri rusange. Uyu muti ni umwe mu miti ikoreshwa cyane ku isi hose kandi wafashije abantu babarirwa muri za miliyoni kongera kumva bameze neza.

Levothyroxine ni iki?

Levothyroxine mu by'ukuri ni verisiyo yakozwe n'abantu ya thyroxine, izwi kandi nka T4, uyu akaba ari umusemburo nyamukuru umubiri wawe wa thyroïde ukora mu buryo bwa kamere. Umubiri wawe wa thyroïde, uherereye mu ijosi ryawe, ukora nk'ikigo gicunga imikorere y'umubiri wawe. Iyo itakora umusemburo uhagije, imikorere yawe yose irashobora kugenda gahoro, bigira ingaruka ku bintu byose kuva ku rwego rw'imbaraga zawe kugeza ku mutima wawe.

Verisiyo ya gihanga iri muri levothyroxine isa neza n'iyo umubiri wawe ukora mu buryo bwa kamere. Ibi bivuze ko umubiri wawe ushobora kuyikoresha neza nk'uko ukoresha umusemburo wawe wa thyroïde. Bitekereze nk'uko uha umubiri wawe amavuta ukeneye kugira ngo ukore ku muvuduko ukwiye igihe thyroïde yawe idashoboye gukora nk'uko bikwiye.

Levothyroxine ikoreshwa mu iki?

Levothyroxine ikoreshwa cyane mu kuvura hypothyroidism, uburwayi aho umubiri wawe wa thyroïde udakora umusemburo uhagije. Ibi bibaho kenshi kuruta uko wabitekereza, bigira ingaruka ku bantu bagera kuri 5%, aho abagore bashobora kurwara inshuro eshanu kugeza ku munani kurusha abagabo.

Usibye hypothyroidism, abaganga bandika levothyroxine kubera izindi ndwara zifitanye isano na thyroïde. Hano hari ibikoreshwa by'ingenzi umuganga wawe ashobora kugusaba:

• Indwara ya Hashimoto, indwara y’ubwirinzi yangiza buhoro buhoro umusonga wawe
• Ubuvuzi bwa kanseri y’umusonga, akenshi nyuma yo kubaga umusonga
• Gukumira no kuvura goiter, iyo umusonga wagutse ukeneye guhagarika imisemburo
• Kugabanya imisemburo ya thyroid nyuma yo kubagwa umusonga
• Hypothyroidism y'abana bavuka badafite umusonga ukora neza

Mu bindi bihe, abaganga bashobora kwandika levothyroxine kuri subclinical hypothyroidism, aho urwego rwawe rw'imisemburo ya thyroid ruri hasi ariko urimo guhura n'ibimenyetso. Muganga wawe azasuzuma neza niba ubuvuzi bukwiye kuri wowe.

Levothyroxine ikora ite?

Levothyroxine ikora isimbura imisemburo ya thyroid umubiri wawe utabasha gukora bihagije. Umaze kuyifata, umubiri wawe uhindura levothyroxine zimwe muri T3 ikora cyane, ikora ku ngingo zawe n'imikorere yawe.

Uyu muti ufatwa nk'uvura neza kandi wizerwa kuko utanga urwego rwa hormone ruhamye kandi ruhuza igihe cyose ufashwe neza. Bitandukanye n'imiti imwe ikora vuba, levothyroxine ifata igihe kugirango yubake mu mubiri wawe kandi yerekane ingaruka zayo zose. Abantu benshi batangira kumva barushaho kumera neza mu byumweru 4-6 nyuma yo gutangira kuvurwa, nubwo hariho impinduka zishobora kugaragara mbere.

Umubiri wawe ukoresha uyu musemburo kugirango ugengere imikorere ya buri selile. Iyo urwego rugarutse mu buryo busanzwe, imbaraga zawe zigaruka, umuvuduko w'umutima wawe urasanzwe, n'ibindi bimenyetso bya hypothyroidism bigenda birushaho kumera neza. Uyu muti ufasha umubiri wawe gukora nkaho umusonga wawe ukora neza.

Nkwiriye gufata levothyroxine nte?

Gufata levothyroxine neza ni ngombwa kugira ngo ikore neza. Igihe n'uburyo bwo gufata uyu muti bishobora kugira uruhare runini mu buryo umubiri wawe uyiinjiza, bityo gukurikiza amabwiriza neza bituma umuntu yumva atandukanye.

Fata levothyroxine ku gifu cyambaye ubusa, byaba byiza iminota 30-60 mbere ya saa sita cyangwa mbere yo kuryama, byibuze amasaha 3-4 nyuma y'ifunguro ryawe rya nyuma. Ibi bituma umubiri wayinjiza neza kuko ibiryo, cyane cyane ibirimo fibre nyinshi, kalisiyumu, na fer, bishobora kubuza umubiri wawe gukoresha umuti uko bikwiye.

Amazi niyo meza yo gufata levothyroxine. Irinde kuyifata hamwe na kawa, amata, cyangwa izindi nzoga, kuko ibi bishobora kugabanya iyinjizwa ryayo. Niba ukunda kuyifata mbere yo kuryama, menya neza ko utariye ikintu icyo aricyo cyose mbere y'amasaha 3-4.

Kugira umuco mwiza ni ingenzi kuri levothyroxine. Yifate ku gihe kimwe buri munsi kugira ngo ugumane urugero rwa hormone mu mubiri wawe. Abantu benshi basanga gushyiraho alarme ya buri munsi ibafasha kwibuka, cyane cyane mu byumweru bike bya mbere by'imiti.

Niba ukeneye gufata indi miti cyangwa ibyongerera imbaraga, kubitandukanya na levothyroxine ni ingenzi. Ibiyongerera kalisiyumu, fer, antacids, n'indi miti imwe n'imwe bigomba gufatwa byibuze amasaha 4 bitandukanye na levothyroxine kugira ngo birinde guhura kw'imiti.

Nzagomba Kumara Igihe Kingana Iki Ndafata Levothyroxine?

Abantu benshi bafite hypothyroidism bagomba gufata levothyroxine ubuzima bwabo bwose. Ibi ntibiterwa n'uko umuti ufata umuntu mu mutwe, ahubwo ni uko indwara yateye thyroid yawe gukora nabi akenshi itikiza yonyine.

Ariko, hariho ibintu bike byihariye aho kuvurwa bishobora kuba by'igihe gito. Niba hypothyroidism yawe yaratewe n'imiti imwe n'imwe, postpartum thyroiditis, cyangwa ubundi bwoko bwo kubyimba kwa thyroid, muganga wawe ashobora kuzagerageza kugabanya cyangwa guhagarika umuti kugira ngo arebe niba imikorere ya thyroid yawe yagarutse.

Muganga wawe azagenzura imikorere y'umusemburo wa thyroïde ukoresheje ibizamini by'amaraso buri gihe, akenshi buri mezi 6-12 igihe urugero rwawe rumeze neza. Ibi bizamini bifasha kumenya neza ko urimo gufata umuti ukwiye kandi ko urugero rwa thyroïde yawe rukomeza kuba rwiza ku buzima bwawe.

Ntuzigere uhagarika gufata levothyroxine mu buryo butunguranye utabanje kubiganiraho n'umuganga wawe. Umubiri wawe wishingikiriza kuri uyu muti usimbura imisemburo, kandi guhagarika mu buryo butunguranye bishobora gutuma ibimenyetso bya hypothyroidism yawe bisubira, rimwe na rimwe bikaba bikomeye kurusha mbere.

Ni Ibihe Bimenyetso Bigaragara Byatewe na Levothyroxine?

Iyo ifashwe ku rugero rukwiye, levothyroxine akenshi itera ibimenyetso bike cyane kuko isimbura gusa icyo umubiri wawe wagombye gukora mu buryo busanzwe. Ibimenyetso byinshi bigaragara bibaho iyo urugero ruri hejuru cyane, mu by'ukuri bigakora igihe gito cya hyperthyroïde.

Dore ibimenyetso bisanzwe ushobora guhura nabyo, cyane cyane igihe utangira kuvurwa cyangwa uhindura urugero:

• Umutima guteragura cyane cyangwa umuvuduko w'umutima wihuta
• Kumva uhangayitse, utuje cyangwa udashize amanga
• Kugorwa no gusinzira cyangwa kumva ufite imbaraga nyinshi
• Ubukana bw'irari ryo kurya ariko utiyongera ibiro
• Guhinda umushyitsi gake mu ntoki zawe
• Kumva ushyushye cyane cyangwa ukabukwa cyane kurusha uko bisanzwe
• Kutakaza umusatsi by'igihe gito mu mezi make ya mbere yo kuvurwa

Ibi bimenyetso akenshi biragenda uko umubiri wawe wimenyereza umuti cyangwa igihe muganga wawe ahindura urugero rwawe. Abantu benshi basanga ibimenyetso byose by'ibanze bigabanuka mu byumweru bike.

Ibimenyetso bikomeye biragoye ariko bisaba ubufasha bwihuse bw'abaganga. Vugana n'umuganga wawe ako kanya niba wumva ububabare mu gituza, umutima uteragura cyane, kugorwa no guhumeka, cyangwa ibimenyetso byo kwanga umuti nk'uruhu ruruka, kubyimba, cyangwa kugorwa kumeza.

Abantu bamwe bahangayika ku ngaruka zirambye, ariko imyaka myinshi y’ubushakashatsi yerekana ko levothyroxine ikoreshwa neza kandi ifite umutekano mwinshi mu gihe kirekire. Inyungu zo kuvura hypothyroidism ziruta cyane ibyago bito iyo umuti ukoreshwa neza.

Ninde utagomba gufata Levothyroxine?

Levothyroxine muri rusange ifitiye abantu benshi umutekano, ariko ibibazo bimwe na bimwe bisaba kwitonda cyane cyangwa bishobora gutuma uyu muti utabera. Muganga wawe azasuzuma neza amateka yawe y'ubuzima mbere yo kugutera uyu muti.

Abantu bafite adrenal insufficiency itavuwe ntibagomba gufata levothyroxine kugeza igihe ikibazo cyabo cya adrenal gicungwa neza. Gufata imisemburo ya thyroid iyo imitsi yawe ya adrenal idakora neza birashobora gutuma adrenal crisis irushaho kuba mibi, ikibazo gishobora guteza akaga mu buzima.

Niba ufite ibibazo by'umutima, muganga wawe ashobora gukenera gutangira kugutera urugero ruto kandi akagukurikiranira hafi. Ibi birimo abantu bafite indwara ya coronary artery, guhagarara k'umutima, cyangwa amateka yo gufatwa n'umutima. Uyu muti ushobora kongera umuvuduko w'umutima n'umurimo ku mutima wawe.

Dore izindi mimerere aho levothyroxine isaba kwitonderwa by'umwihariko:

• Gusama no konsa (muri rusange bifite umutekano ariko bisaba guhindura urugero)
• Abageze mu zabukuru, cyane cyane abarengeje imyaka 65 bafite ibibazo by'umutima
• Abantu barwaye diyabete, kuko imisemburo ya thyroid ishobora kugira ingaruka ku rugero rw'isukari mu maraso
• Abafite osteoporosis, kuko imisemburo ya thyroid irenze urugero ishobora kugira ingaruka ku gukomera kw'amagufa
• Abantu bafite indwara zo gufatwa n'ibihungabanyo, kuko imisemburo ya thyroid ishobora kugabanya urugero rwo gufatwa n'ibihungabanyo

Niba ufite kimwe muri ibi bibazo, ntugire impungenge - ntibisobanura neza ko udashobora gufata levothyroxine. Muganga wawe azakorana nawe kugirango amenye uburyo bufite umutekano kurusha ubundi kandi ashobora gutangira urugero ruto cyangwa akagukurikiranira kenshi.

Amazina y'ubwoko bwa Levothyroxine

Levothyroxine iboneka mu mazina menshi y'ubucuruzi, aho Synthroid ari ryo rizwi cyane. Andi mazina akunda gukoreshwa arimo Levoxyl, Tirosint, na Unithroid, buri rimwe rifite uburyo buke butandukanye ariko rifite ikintu kimwe gikora.

Abantu benshi babana neza na levothyroxine rusange, ihendutse cyane kurusha izina ry'ubucuruzi. Ariko, hari abantu basanga bumva bameze neza ku izina ryihariye bitewe n'itandukaniro riri mu bintu bitagira akamaro cyangwa uburyo bwo gukora.

Niba uri gukoresha izina ry'ubucuruzi, ntukimurire kuri rusange (cyangwa ibinyuranye) utabanje kubaza muganga wawe. Nubwo zifite ikintu kimwe gikora, umubiri wawe ushobora kuzinjiza mu buryo butandukanye gato, bigasaba guhindura urugero.

Tirosint ni uburyo bushya buza mu gace ka gel kandi bufite ibintu bike bitagira akamaro. Abantu bamwe bafite ibibazo n'ibinini bisanzwe bitewe n'allergies cyangwa ibibazo byo kwinjiza bashobora kungukira kuri ubu buryo.

Uburyo bwo gusimbuza Levothyroxine

Mugihe levothyroxine ariyo nzira nziza yo kuvura hypothyroidism, hariho uburyo buke bwo gusimbuza buhari kubantu batitabira neza cyangwa bafite ibibazo byihariye by'ubuvuzi.

Thyroid y'umwimerere (NDT), igurishwa mu mazina y'ubucuruzi nka Armour Thyroid na Nature-Throid, irimo imisemburo ya T4 na T3 yakurwa mu ngingo za thyroid z'ingurube. Abantu bamwe bumva bameze neza kuri NDT, nubwo ibimenyetso bya siyansi biterekana neza ko iruta levothyroxine kubarwayi benshi.

T3 ya sintetike (liothyronine) rimwe na rimwe yandikirwa wenyine cyangwa hamwe na levothyroxine. Ibi bikunze kubikwa kubantu bafite ingorane zo guhindura T4 kuri T3 mumibiri yabo, nubwo ibi bidakunze kubaho.

Ubuvuzi buhuriweho bukoresha levothyroxine na liothyronine ni ubundi buryo abaganga bamwe bateganya. Ubushakashatsi buriho butanga igitekerezo ko ubu buryo bushobora gufasha itsinda rito ry'abarwayi batumva bameze neza kuri levothyroxine yonyine.

Abahanga mu by'imikorere y'imitsi y'imbere mu mubiri (endocrinologists) benshi baracyakunda levothyroxine nk'umuti wa mbere kuko wize, wamenyekanye, kandi ukora ku bantu benshi. Niba utiyumva neza ukoresha levothyroxine, ganira na muganga wawe ku bijyanye no kunoza urugero rwawe rwa ubu mbere yo gutekereza ku bindi bisimbura.

Ese Levothyroxine iruta Synthroid?

Levothyroxine na Synthroid birimo ikintu kimwe gikora - levothyroxine sodium. Synthroid ni izina ry'ubucuruzi rya levothyroxine, bityo ni imiti imwe ifite ingaruka zimwe zo kuvura.

Itandukaniro rikuru riri mu bintu bitagira akamaro n'inzira zo gukora. Synthroid imaze igihe kinini kandi ifite amakuru menshi ya kliniki, niyo mpamvu abaganga bamwe bayikunda. Ariko, levothyroxine rusange yemewe na FDA kandi isa na Synthroid, bivuze ko igomba gukora neza.

Abantu bamwe bavuga ko bumva bameze neza bakoresha Synthroid ugereranije na levothyroxine rusange, mu gihe abandi batabona itandukaniro na gato. Iri tandukaniro ry'umuntu ku giti cye rishobora guterwa n'itandukaniro ry'uburyo umubiri wawe ukoresha ibintu bitagira akamaro cyangwa itandukaniro rito mu gukora.

Igiciro akenshi ni ikintu cy'ingenzi mu gufata icyemezo. Levothyroxine rusange akenshi ihendutse cyane kurusha Synthroid, bituma iboneka cyane mu kuvura igihe kirekire. Niba ukora neza ukoresha levothyroxine rusange, akenshi nta mpamvu yo guhindukira ku izina ry'ubucuruzi.

Niba utekereza guhindura hagati ya verisiyo rusange n'izina ry'ubucuruzi, banza uganire n'umuganga wawe. Bashobora gushaka kongera gusuzuma urugero rwawe rwa thyroid nyuma y'ibyumweru 6-8 nyuma yo guhindura kugirango barebe niba urugero rwa hormone rwawe rukomeza kuba rwiza.

Ibikunze Kubazwa Kuri Levothyroxine

Ese Levothyroxine irakwiriye ku ndwara z'umutima?

Levothyroxine irashobora kuba umutekano ku bantu barwaye indwara z'umutima, ariko bisaba kugenzurwa na muganga. Muganga wawe ashobora gutangira kuguha urugero ruto hanyuma akaruzamura buhoro buhoro kugirango wirinde gushyira umutwaro mwinshi ku mutima wawe.

Hypothyroidism itavurwa ishobora rwose gushimangira indwara z'umutima mugihe yongera urugero rwa cholesterol no kugabanya imikorere y'umutima. Iyo itanzwe neza, levothyroxine akenshi ituma umutima ugira ubuzima bwiza mugihe isubiza metabolism isanzwe kandi igabanya ibintu byongera ibyago byo mu mutima.

Niba urwaye indwara z'umutima, muganga wawe azagukurikiranira hafi mugihe uvurwa, ahari hamwe n'ibizamini by'amaraso bya kenshi no gukurikiranira hafi umutima. Bazakorana kugirango babone uburyo bukwiye bwo kuvura hypothyroidism yawe no kurengera ubuzima bw'umutima wawe.

Nkwiriye gukora iki niba nanyweye levothyroxine nyinshi bitunguranye?

Niba unyweye urugero rwa levothyroxine rwinshi bitunguranye, ntugire ubwoba. Urugero rumwe rwinshi ntirushobora guteza ingaruka zikomeye, ariko ushobora guhura n'ibimenyetso nk'umutima utera cyane, guhangayika, cyangwa kumva utuje muminsi mike.

Vugana na muganga wawe cyangwa umufarumasiti kugirango baguhe ubuyobozi, cyane cyane niba unyweye byinshi cyane kuruta urugero rwanditswe. Barashobora kukugira inama niba ukeneye ubufasha bwa muganga n'uburyo wakosora gahunda yawe yo kunywa imiti.

Ntugasibe urugero rwawe rukurikira kugirango "ukosore" kunywa byinshi - ibi bishobora gutuma urugero rwa hormone yawe ruzamuka no kumanuka. Ahubwo, garuka kuri gahunda yawe isanzwe yo kunywa imiti keretse niba umuganga wawe abigushishikarije.

Niba uhuye n'ibimenyetso bikomeye nk'ububabare mu gituza, umutima utera cyane, cyangwa guhumeka bigoye nyuma yo kunywa byinshi, shakisha ubufasha bwa muganga ako kanya. Ibi bishobora kuba ibimenyetso by'umuyaga wa thyroid, nubwo ibi bidasanzwe cyane hamwe na levothyroxine.

Nkwiriye gukora iki niba nirengagije urugero rwa levothyroxine?

Niba wibagiwe gufata urugero rwa levothyroxine, rufate uko wibuka, keretse igihe cyo gufata urugero rukurikira kigeze. Mu gihe nk'icyo, reka urugero wibagiwe rukure, ukomeze gahunda yawe isanzwe - ntufate urugero ebyiri icyarimwe.

Kubera ko levothyroxine ifite igihe kirekire cyo gukora, kwibagirwa urugero rimwe rimwe ntizatera ibibazo ako kanya. Ariko, gerageza kugira gahunda ihamye kuko gufata imiti buri gihe bifasha kugumisha urugero rw'imisemburo yawe mu buryo buhamye.

Niba ukunda kwibagirwa gufata imiti, tekereza gushyiraho alarme ya buri munsi cyangwa gukoresha umuteguro w'imiti. Abantu bamwe basanga bifasha kubika imiti yabo hafi y'urubavu rw'igitanda cyangwa ku ruganda rwa kawa nk'urwibutso rugaragara.

Niba umaze kwibagirwa urugero rwinshi, ntugerageze kwishyura ufata ibinini byinshi. Vugana na muganga wawe kugira ngo akuyobore uko wasubira muri gahunda yawe isanzwe yo gufata imiti mu buryo bwizewe.

Ni ryari nshobora kureka gufata levothyroxine?

Abantu benshi bafite hypothyroidism bakeneye kuvurwa ubuzima bwabo bwose na levothyroxine. Ibyo bitera hypothyroidism, nk'uko Hashimoto's thyroiditis cyangwa kubagwa kwa thyroïde, mubisanzwe ntibikira byonyine.

Ariko, hariho ibihe bimwe na bimwe aho muganga wawe ashobora gutekereza kureka kuvura. Ibi birimo ibitera hypothyroidism by'igihe gito nk'uko postpartum thyroiditis, imiti imwe n'imwe, cyangwa ubwoko bumwe na bumwe bwo guhura kwa thyroïde bishobora gukira nyuma y'igihe.

Muganga wawe azagira icyemezo gishingiye ku burwayi bwawe bwihariye, igihe umaze uvurwa, n'ibizamini byawe bya thyroïde bya none. Bashobora kugabanya buhoro buhoro urugero rwawe mu gihe bakurikirana urugero rwa thyroïde yawe kugira ngo barebe niba imikorere ya thyroïde yawe isanzwe yarakize.

Ntuzigere ureka gufata levothyroxine wenyine, n'iyo wumva umeze neza. Ibimenyetso byawe bishobora kugaruka buhoro buhoro, kandi guhagarara ako kanya rimwe na rimwe bishobora gutuma bigaruka mu buryo bukomeye kurusha mbere yo kuvurwa.

Nshobora gufata levothyroxine mu gihe cyo gutwita?

Levothyroxine ntabwo ari nziza gusa mu gihe cyo gutwita, ahubwo akenshi ni ingenzi ku buzima bw'umubyeyi n'umwana uri mu nda. Hypothyroidism mu gihe cyo gutwita ishobora kongera ibyago byo kugira ibibazo nk'indwara ya preeclampsia, kuvuka imburagihe, n'ibibazo by'imikurire ku mwana.

Abagore benshi bakeneye kongera urugero rwa levothyroxine bafata mu gihe cyo gutwita kuko ibisabwa bya hormone ya thyroid akenshi byiyongera. Muganga wawe azagenzura urugero rwa thyroid yawe kenshi mu gihe cyo gutwita kandi ahindure urugero rwawe uko bikwiye.

Niba uteganya gutwita cyangwa umaze kumenya ko utwite, bimenyeshe muganga wawe ako kanya. Birashoboka ko bazashaka kureba urugero rwa thyroid yawe kandi bashobora kongera urugero rwawe mbere yuko ibimenyetso bigaragara.

Levothyroxine kandi ni nziza mu gihe cyo konsa kandi ifasha kureba ko ufite imbaraga n'ubuzima bikenewe kugira ngo witwararike umwana wawe. Urugero ruto rwinjira mu mata ntirugira ingaruka ku bana bonsa.