Linezolid ni iki: Ibikoreshwa, Urutonde rw'imiti, Ingaruka ziterwa n'iyo miti n'ibindi

Linezolid ni umuti ukomeye urwanya mikorobe urwanya indwara ziterwa na bagiteri zikomeye iyo indi miti itagikora. Uyu muti ubarizwa mu cyiciro cyihariye cy'imiti irwanya mikorobe yitwa oxazolidinones, bivuze ko ikora mu buryo butandukanye n'imiti myinshi isanzwe irwanya mikorobe ushobora kuba uzi.

Uyu muti akenshi ukoreshwa mu kurwanya indwara zikomeye kuko abaganga bawita umuti wa nyuma. Muganga wawe ashobora kuba yaraguteye uyu muti kuko bakeneye ikintu gikomeye kandi gifasha umubiri wawe kurwanya indwara iterwa na bagiteri.

Linezolid ikoreshwa mu kurwanya iki?

Linezolid ivura indwara ziterwa na bagiteri zikomeye zititabira imiti irwanya mikorobe. Ifasha cyane mu kurwanya ubwoko runaka bwa bagiteri bwanze imiti myinshi.

Muganga wawe ashobora kugutera linezolid niba ufite indwara ikomeye y'uruhu, umusonga, cyangwa indwara yo mu maraso iterwa na bagiteri zimwe na zimwe nka MRSA (methicillin-resistant Staphylococcus aureus) cyangwa VRE (vancomycin-resistant Enterococcus). Izi ni bagiteri zanze imiti myinshi isanzwe irwanya mikorobe.

Uyu muti kandi ukoreshwa mu kurwanya indwara zikomeye zo mu bitaro, zirimo izibasira ibihaha, uruhu, n'imitsi yoroshye. Rimwe na rimwe abaganga bawutera abantu batitabira indi miti irwanya mikorobe.

Linezolid ikora ite?

Linezolid ikora ibuza bagiteri gukora poroteyine zikeneye kugira ngo zibaho kandi zigwiri. Bitekereze nk'uko ihungabanya ubushobozi bwa bagiteri bwo kubaka ibintu by'ingenzi bakeneye kugira ngo zikomeze kubaho.

Ibi bituma linezolid ari icyo abaganga bita umuti wa

Uyu muti ufatwa nk'umuti ukomeye kandi ukora neza, ni yo mpamvu akenshi ubikwa ku ndwara zikomeye zandura. Ushobora kugera mu bice byinshi by'umubiri wawe, harimo n'ahantu izindi antibiyotike zitabasha kugera.

Nkwiriye gufata Linezolid nte?

Fata linezolid nk'uko umuganga wawe abikwandikiye, akenshi buri masaha 12 ufata cyangwa utafata ibiryo. Urashobora kuyifata unywa ikirahure cy'amazi, kandi birakwiriye kuyifata hamwe n'ibiryo niba bifasha kwirinda kuribwa mu nda.

Gerageza gufata imiti yawe ku gihe kimwe buri munsi kugira ngo urinde urugero rwawo mu mubiri wawe. Gushyiraho alarme kuri terefone birashobora kugufasha kwibuka, cyane cyane kuko kutafata imiti bishobora gutuma indwara igorana kuvurwa.

Mugihe ufata linezolid, uzakenera kwitondera ibyo urya n'ibyo unywa. Uyu muti ushobora guhura n'ibiryo birimo tyramine nyinshi, harimo foromaje zishaje, inyama zitunganyirijwe, ibiryo byasembuye, n'ibinyobwa bisembuye bimwe na bimwe. Umuganga wawe cyangwa umufarimasi akwiriye kuguha urutonde rwuzuye rw'ibiryo byo kwirinda.

Ntugasenye, utahe cyangwa ucagagure ibinini keretse umuganga wawe akubwiye byumwihariko. Niba ufata urugero rw'amazi, menya kuyivanga neza mbere yo gufata buri dose kandi ukoreshe igikoresho gipima kiza hamwe nayo.

Nkwiriye gufata Linezolid igihe kingana iki?

Abantu benshi bafata linezolid iminsi 10 kugeza kuri 28, bitewe n'ubwoko n'uburemere bw'indwara yabo. Umuganga wawe azagena igihe nyacyo cyo kuvurwa bitewe n'uko umubiri wawe witwara ku muti.

Ni ngombwa kurangiza umuti wose wa antibiyotike, kabone niyo watangira kumva umerewe neza nyuma y'iminsi mike. Guhagarika kare bishobora korohereza bagiteri kugaruka kandi bishobora gutuma zirwanya imiti.

Ku ndwara zikomeye zimwe na zimwe, ushobora gukenera gufata linezolid mu byumweru byinshi. Umuganga wawe azakurikiza iterambere ryawe binyuze mu kugenzura buri gihe kandi birashoboka ko hazakorwa ibizamini by'amaraso kugirango barebe neza ko umuti ukora neza.

Ntugasize gufata linezolid mu buryo butunguranye utabanje kuvugana na muganga wawe. Ashobora kwifuza kugabanya urugero rwawe buhoro buhoro cyangwa akaguherereza izindi nzitiramuganda kugira ngo urangize imiti yawe.

Ni Ibihe Bikorwa Bigaragara Byo Ku Ruhande Bya Linezolid?

Kimwe n'imiti yose, linezolid ishobora gutera ibikorwa bigaragara ku ruhande, nubwo atari buri wese ubyumva. Ibikorwa byinshi bigaragara ku ruhande birashobora gucungwa kandi bikagenda umaze kurangiza imiti.

Dore bimwe mu bikorwa bisanzwe bigaragara ku ruhande ushobora kubona mugihe ufata linezolid:

• Urugimbu no kuruka
• Impiswi cyangwa imyanda yoroshye
• Umutwe
• Urugero
• Kugorana gusinzira
• Impinduka mu buryohe
• Urubu mu nda cyangwa kutumva neza

Ibi bimenyetso mubisanzwe biroroshye kandi akenshi birakosoka umubiri wawe umaze kumenyera umuti. Gufata linezolid hamwe n'ibiryo birashobora gufasha kugabanya ibikorwa bigaragara ku ruhande bifitanye isano n'inda.

Abantu bamwe bashobora guhura n'ibikorwa bigaragara ku ruhande bikomeye bisaba ubufasha bwihuse bwa muganga. Ibi ntibisanzwe ariko ni ngombwa kubitegereza:

• Impiswi ikomeye ishobora kuba irimo amaraso
• Umunaniro udasanzwe cyangwa intege nke
• Kugurumana cyangwa guhuma mu ntoki cyangwa mu birenge
• Impinduka mu burebure cyangwa guhuma
• Umutwe ukomeye hamwe no gukakara mu ijosi
• Gukomeretsa cyangwa kuva amaraso byoroshye
• Ibimenyetso byo kwandura nk'umuriro cyangwa kubabara mu muhogo

Niba ubonye kimwe muri ibi bimenyetso bikomeye, vugana na muganga wawe ako kanya. Bashobora gufasha kumenya niba ukeneye guhindura imiti yawe cyangwa guhindurira ku yindi miti.

Ni Bande Batagomba Gufata Linezolid?

Linezolid ntabwo ikwiriye kuri buri wese, kandi muganga wawe azasuzuma neza amateka yawe y'ubuzima mbere yo kuyandika. Ubuzima bumwe n'imiti ishobora gutuma linezolid idatekanye cyangwa idakora neza.

Ntabwo ugomba gufata linezolid niba uri gufata imiti imwe na imwe ivura umubabaro, cyane cyane iyo bita MAO inhibitors, cyangwa niba wayifashe mu byumweru bibiri bishize. Ubu buryo bushobora gutera izamuka ry'ubwoba mu maraso.

Abantu bafite umuvuduko ukabije w'amaraso utagenzurwa, indwara zimwe na zimwe z'umutima, cyangwa abafata imiti ivura ADHD bagomba kuganira kuri izo ndwara na muganga wabo mbere yo gutangira gufata linezolid. Uyu muti ushobora gukururana n'izo ndwara n'imiti.

Niba ufite amateka y'indwara z'amaraso, ibibazo by'impyiko, cyangwa indwara y'umwijima, muganga wawe azagomba kugukurikiranira hafi igihe ufata linezolid. Izi ndwara zishobora kugira ingaruka ku buryo umubiri wawe ukoresha uyu muti.

Abagore batwite kandi bonsa bagomba gufata linezolid gusa niba inyungu zishoboka zirenze ibyago. Muganga wawe azagereranya neza ibi bintu kandi ashobora gushimangira imiti isimbura niba iboneka.

Amazina y'ubwoko bwa Linezolid

Linezolid iboneka munsi y'izina ry'ubwoko bwa Zyvox, rikaba ari ryo rikoreshwa cyane. Byombi izina ry'ubwoko na verisiyo rusange birimo ibintu bikora kimwe kandi bikora neza kimwe.

Farumasi yawe ishobora kugira izina ry'ubwoko cyangwa verisiyo rusange, bitewe n'ubwishingizi bwawe n'uko biboneka. Ubu bwoko bwombi buza mu buryo bwa tablet na liquid yo gukoreshwa mu kanwa.

Niba uhindura hagati y'amazina y'ubwoko na verisiyo rusange, menya neza gukurikiza gahunda imwe yo gufata imiti n'amabwiriza. Icyo gipaki gishobora kugaragara ukundi, ariko umuti uri imbere ukora kimwe.

Uburyo bwo gusimbuza Linezolid

Izindi antibiyotike nyinshi zishobora gukoreshwa nk'izisimbuza linezolid, bitewe n'ubwoko bw'indwara n'agakoko gatera indwara. Muganga wawe azahitamo uburyo bwiza bushingiye ku miterere yawe yihariye.

Ku ndwara ziterwa na MRSA, izindi nzira zishobora gukoreshwa zirimo vancomycin, daptomycin, cyangwa clindamycin. Buri kimwe muri ibi gikora mu buryo butandukanye kandi gishobora gutangwa mu kanwa, hakoreshejwe urushinge mu urwungano rw'amaraso (IV), cyangwa nk'umuti ushyirwa ku ruhu.

Izindi nzira zirimo tedizolid, iheruka kandi isa na linezolid ariko ishobora gufatwa mu gihe gito. Ceftaroline ni indi nzira ishobora kuvura mikorobe zimwe na zimwe zananiranye.

Muganga wawe azatekereza ku bintu nk'aho indwara yawe iherereye, imikorere y'impyiko n'umwijima wawe, imiti indi urimo gufata, n'uburwayi bwose ufite iyo ahitamo uburyo bwiza.

Ese Linezolid iruta Vancomycin?

Linezolid na vancomycin ni imiti yombi ikora neza ku ndwara zikomeye ziterwa na mikorobe, ariko zikora mu buryo butandukanye kandi zifite inyungu zitandukanye. Guhitamo

Muganga wawe ashobora kwifuza gukurikiranira hafi isukari yo mu maraso yawe igihe uri gufata linezolid. Wibuke gukomeza gufata imiti yawe ya diyabete nk'uko byategetswe kandi upime isukari yo mu maraso yawe nk'uko byasabwe.

Niba ubonye impinduka zidasanzwe mu rugero rw'isukari yo mu maraso yawe cyangwa ibimenyetso nk'inyota yiyongereye, kunyara kenshi, cyangwa umunaniro, vugana n'umuganga wawe ako kanya.

Nkwiriye gukora iki niba nifatiye linezolid nyinshi ku buryo butunguranye?

Niba ufatiye linezolid nyinshi ku buryo butunguranye kurusha uko byategetswe, vugana n'umuganga wawe cyangwa ikigo gishinzwe kurwanya uburozi ako kanya. Gufata nyinshi bishobora kongera ibyago byo kugira ingaruka zikomeye.

Ibimenyetso bisanzwe byo gufata linezolid nyinshi bishobora kuba isesemi ikabije, kuruka, impiswi, cyangwa umunaniro udasanzwe. Ntukegere ngo urebe niba ibimenyetso bigaragara - shaka inama z'ubuvuzi ako kanya.

Bika urupapuro rw'umuti hamwe nawe igihe uhamagaye cyangwa ujya gushaka ubufasha bw'ubuvuzi, kuko iyi makuru izafasha abaganga kumenya uburyo bwiza bwo gukora.

Nkwiriye gukora iki niba nciwe doze ya linezolid?

Niba waciwe doze ya linezolid, yifate ako kanya wibuka, keretse igihe kigeze cyo gufata doze yawe ikurikira. Muri icyo gihe, reka doze waciwe hanyuma ufate doze yawe ikurikira ku gihe gisanzwe.

Ntuzigere ufata doze ebyiri icyarimwe kugira ngo usimbure doze waciwe, kuko ibi bishobora kongera ibyago byo kugira ingaruka zikomeye. Ahubwo, komeza gahunda yawe isanzwe yo gufata imiti.

Niba ukunda kwibagirwa doze, gerageza gushyiraho alarme kuri terefone cyangwa ukoreshe umuteguro w'imiti kugira ngo ukwibutse. Gufata imiti buri gihe ni ngombwa kugira ngo umuti ukore neza ku ndwara yawe.

Nshobora guhagarika ryari gufata linezolid?

Hagarika gufata linezolid gusa igihe muganga wawe abikubwiye, n'iyo wumva umeze neza rwose. Guhagarika imiti yica mikorobe kare cyane bishobora korohereza bagiteri kubaho kandi bikaba bishobora kurwanya imiti.

Umuganga wawe azagena igihe cyiza cyo guhagarika bitewe n'ibimenyetso byawe, ibisubizo by'ibizamini, n'igihe cy'isanzwe cyo kuvura ubwoko bw'indwara ufite. Ibi bikunda kuba nyuma yo kurangiza umuti wose wategetswe.

Niba ubonye ingaruka zikomeye, vugana n'umuganga wawe mbere yo guhagarika umuti. Bashobora gukenera guhindura urugero rwawo cyangwa kuguha umuti utandukanye aho guhagarika kuvurwa burundu.

Nshobora kunywa inzoga nkorera Linezolid?

Ni byiza kwirinda inzoga mugihe ukoresha linezolid, cyane cyane ubwoko bumwe na bumwe bw'inzoga. Uyu muti ushobora gukorana n'inzoga mu buryo bushobora gutera ingaruka zitari nziza cyangwa ziteje akaga.

Divayi zishaje, inzoga, n'ibindi binyobwa bisembuye bikubiyemo tyramine, ishobora gukorana na linezolid kandi igatuma umuvuduko w'amaraso wiyongera mu buryo butunguranye kandi buteye akaga. Iyi ni yo mpamvu ugomba kwirinda ibiryo bimwe na bimwe.

Niba uhisemo kunywa inzoga rimwe na rimwe, jya ku binyobwa bito bya spirit, nka vodka cyangwa gin, kandi buri gihe banza ubaze umuganga wawe. Bashobora kuguha ubujyanama bwihariye bushingiye ku buzima bwawe n'indi miti ufata.