Liothyronine (Uburyo bwo mu mitsi): Ibikoreshwa, Urutonde rw'imiti, Ingaruka ziterwa n'iyo miti n'ibindi

Liothyronine yo mu mitsi ni ubwoko bwa hormone ya T3 ya thyroid ikorwa mu buryo bwa gihanga itangwa mu maraso yawe binyuze mu muyoboro wa IV. Uyu muti ukoreshwa mu bihe bikomeye, bishobora gutera urupfu aho urugero rwa thyroid rwawe ruri hasi cyane kandi rugomba gukosorwa ako kanya.

Bitandukanye na tablet zinyobwa ushobora kumenyera, liothyronine ya IV ikora mu masaha aho gukora mu minsi. Ikoreshwa cyane mu bitaro iyo imikorere ya thyroid y'umuntu yagabanutse cyane ku buryo gutegereza ko umuti unyobwa ukora byaba ari akaga.

Liothyronine ni iki?

Liothyronine ni ubwoko bwakozwe n'abantu bwa triiodothyronine (T3), imwe muri hormone ebyiri z'ingenzi umubiri wawe wa thyroid ukora mu buryo busanzwe. T3 ni ubwoko bwa hormone ya thyroid ikora cyane igira ingaruka zikomeye ku buryo selile zawe zikoresha imbaraga.

Iyo itanzwe mu mitsi, liothyronine yirengagiza rwose sisitemu yawe yo mu gifu ikinjira mu maraso yawe ako kanya. Ibi bituma ikora vuba cyane kurusha imiti ya thyroid inyobwa, ni yo mpamvu abaganga bayibika mu bihe by'ubutabazi.

Ubwoko bwa IV buhuza neza imisemburo ya T3 umubiri wawe ukora, bityo ishobora kwinjira igakora akazi kamwe iyo thyroid yawe idashobora gukora bihagije ku giti cyayo.

Liothyronine ikoreshwa mu iki?

Liothyronine ya IV ikoreshwa cyane mu kuvura myxedema coma, uburwayi budakunze kubaho ariko butera urupfu aho urugero rwa hormone ya thyroid rugabanuka cyane ku buryo rugira ingaruka ku mikorere y'ubwonko bwawe n'ingingo z'ingenzi. Iki kibazo cy'ubuvuzi gisaba guhita usimbuza hormone kugira ngo wirinde kunanirwa kw'ingingo.

Abaganga kandi barayikoresha mu gihe cyo gukomera kwa hypothyroidism iyo umuntu adashobora gufata imiti inyobwa kubera ibibazo byo mu gifu cyangwa iyo batagira ubwenge kandi badashobora kumira. Rimwe na rimwe ikoreshwa mbere yo kubagwa umutima gukomeye ku barwayi bafite ibibazo bya thyroid bizwi.

Mu bintu bike cyane, bishobora guhabwa umuntu warwaye umusonga akurwamo kandi akagira ibimenyetso bikomeye mbere yuko imiti yo kunywa itangira gukora. Intego ni ukugabanya umurwayi vuba na bwangu hanyuma ugahindukirira gusimbuza imisemburo ya thyroid yo kunywa.

Liothyronine ikora ite?

Liothyronine ikora isimbura umusemburo wa T3 umusonga wawe usanzwe ukora. T3 ifatwa nk'umusemburo wa thyroid "ukora" kuko ubwira mu buryo butaziguye selile zawe uko zikoresha imbaraga vuba kandi zigakora imirimo yazo.

Uyu ni umuti ukomeye ukora vuba cyane kurusha indi misemburo ya thyroid. Mugihe T4 (levothyroxine) ikeneye guhindurwa muri T3 mumubiri wawe, liothyronine imaze kuba mumiterere yayo ikora kandi itangira gukora mumasaha make.

Uburyo bwa IV butuma bukora cyane kuko butanga umusemburo mu maraso yawe nta gutinda kuva mugituntu. Umutima wawe, ubwonko, nizindi ngingo birashobora gutangira gusubiza umusemburo hafi ako kanya, ibyo bikaba ari ngombwa mugihe cyihutirwa.

Nkwiriye gufata Liothyronine nte?

Ntabwo uzifata IV liothyronine ubwawe - uyu muti utangwa nabaganga gusa mubitaro cyangwa ahantu hakorerwa ibizamini. Umuforomo cyangwa muganga bazawutanga banyuze mumurongo wa IV umaze gushyirwa mumitsi yawe.

Umuti uza nkigisubizo gisobanutse kivanzwe namazi atariho mikorobe mbere yuko uguha. Itsinda ryawe ryubuvuzi rizakurikirana neza mugihe cyo gutera no nyuma yuko batera kugirango barebe impinduka zose mumutima wawe, umuvuduko wamaraso, cyangwa ibindi bimenyetso byingenzi.

Niba uri maso mugihe uvurwa, ntugomba kwirinda kurya cyangwa kunywa, ariko itsinda ryawe ryubuvuzi rizagutera amabwiriza yihariye ashingiye kumiterere yawe yose nizindi mvura urimo guhabwa.

Nkwiriye gufata Liothyronine igihe kingana iki?

Liothyronine ya IV akenshi itangwa mu minsi mike gusa, akenshi iminsi 1-3 ntarengwa. Igenewe kuba uburyo bwo kuvura bwihutirwa bw'igihe gito kugira ngo igabanye vuba urugero rw'imisemburo ya thyroïde.

Iyo ubuzima bwawe bwiyongera kandi umaze gukomera, muganga wawe ashobora kukwimurira ku miti ya thyroïde yo kunywa nk'ibinini bya levothyroxine. Guhinduka akenshi bibaho buhoro buhoro kugira ngo byemeze ko urugero rw'imisemburo yawe ruguma rutajegajega.

Igihe nyacyo giterwa n'uburemere bw'uburwayi bwawe n'uko wihutira gusubiza ku buvuzi. Itsinda ryawe ry'abaganga rizasuzuma urugero rw'imisemburo ya thyroïde yawe buri gihe kugira ngo bamenye igihe byemewe guhagarika umuti wa IV.

Ni izihe ngaruka ziterwa na Liothyronine?

Ingaruka zisanzwe zifitanye isano n'umubiri wawe usubiza vuba cyane ku kwiyongera kw'imisemburo ya thyroïde. Ushobora guhura n'umutima utera cyane cyangwa utajegajega, kuribwa mu gituza, cyangwa kubira ibyuya igihe imikorere yawe yihuta.

Abantu bamwe bumva bahangayitse, badatuje, cyangwa bagira ikibazo cyo gusinzira igihe urugero rwa thyroïde rwiyongera vuba. Ushobora kandi kubona umubiri uhinda umushyitsi mu ntoki zawe, kubabara umutwe, cyangwa kumva ushyushye cyangwa ufite amabara atandukanye.

Ingaruka zikomeye zirimo guhinduka kw'umutima ku buryo buteye akaga, cyane cyane niba ufite ibibazo by'umutima. Itsinda ryawe ry'abaganga rizakurikirana umutima wawe buri gihe kugira ngo bamenye impinduka zose ziteye impungenge hakiri kare.

Dore ingaruka ushobora guhura nazo, zashyizwe mu matsinda bitewe n'uko zikunda kubaho:

Ingaruka zisanzwe abantu benshi bahura nazo:

• Umutima utera cyane cyangwa utajegajega
• Kuribwa mu gituza cyangwa gufatana
• Kubira ibyuya cyane kurusha uko bisanzwe
• Kumva uhangayitse cyangwa udatuje
• Umubiri uhinda umushyitsi mu ntoki
• Kubabara umutwe
• Ikibazo cyo gusinzira
• Kumva ushyushye cyangwa ufite amabara atandukanye

Ingaruka zitari nyinshi ariko zikomeye:

• Uburibwe bukomeye mu gituza
• Imikorere y'umutima ihinduka mu buryo buteye ubwoba
• Umubyimba mwinshi cyane
• Kugufiwa cyane k'umwuka
• Urujijo cyangwa umujinya
• Udukorwa (bidakunze kubaho)

Wibuke ko uzagenzurwa cyane mu gihe cyose uvurwa, bityo ikipe yawe y'abaganga ishobore guhita ikemura ingaruka zose zishobora kugaragara. Ingaruka nyinshi zishobora gucungwa kandi zigakira uko umubiri wawe wimenyereza umuti.

Ninde utagomba gufata Liothyronine?

Abantu bafite indwara zimwe na zimwe z'umutima bakeneye kwitonda cyane bakoresha liothyronine yo mu rwego rwa IV kuko ishobora gushyira igihunga ku mikorere y'imitsi y'umutima. Niba ufite indwara ikomeye y'imitsi y'umutima, uherutse kugira umutima utera cyangwa ibibazo by'imikorere y'umutima iteye ubwoba, muganga wawe azagereranya neza ibyago.

Abafite ubusembwa butavurwa bwo mu ngingo zikora imisemburo (iyo imitsi yawe ikora imisemburo idahagije) akenshi ntibashobora guhabwa imisemburo ya thyroid mu buryo bwizewe kugeza igihe indwara yabo yo mu ngingo zikora imisemburo ivuriwe mbere. Ubu buryo bushobora guteza akaga.

Niba ufite allergie kuri liothyronine cyangwa ibintu byose biri mu muti wa IV, ikipe yawe y'abaganga izakeneye gushaka ubundi buryo bwo kuvura. Bazitonda kandi niba ufite umubyimba mwinshi udacungwa neza.

Dore ibintu by'ingenzi aho liothyronine ya IV itashobora gukwira:

Ibyiciro bisaba kwitonda cyane:

• Indwara ikomeye y'umutima cyangwa umutima uherutse gutera
• Ubusumbane butavurwa bwo mu ngingo zikora imisemburo
• Ibibazo by'imikorere y'umutima iteye ubwoba
• Umubyimba mwinshi udacungwa neza
• Thyrotoxicosis ikora (thyroid ikora cyane)
• Allergie zizwi kuri liothyronine

Abantu b'umwihariko bakeneye kugenzurwa neza:

• Abageze mu za bukuru (bafite ibyago byinshi byo kugira ingaruka)
• Abantu barwaye diyabete (bashobora gukenera guhindura imiti)
• Abafata imiti ituma amaraso ataguma gupfundika
• Abarwayi bafite ibibazo by'impyiko cyangwa umwijima

Itsinda ryawe ry’abaganga rizareba neza amateka yawe y’ubuvuzi n’uburwayi bwawe ubu mbere yo gufata icyemezo niba IV liothyronine ikwiriye kuri wowe. Mu bihe by’ubutabazi, barashobora kuyikoresha bakoresheje gukurikiranwa by’umwihariko niba inyungu ziruta ibyago.

Amazina y’ubwoko bwa Liothyronine

Izina risanzwe ry’ubwoko bwa IV liothyronine ni Triostat, ikozwe by’umwihariko kugirango ikoreshwe mu maraso. Ibi bitandukanye n’ubwoko bwa liothyronine yo kunywa ushobora kumenya, nka Cytomel tablets.

Triostat iza mu ifu yoroshye abaganga bo mu bitaro bavanga n’amazi yoroshye mbere yo kuyiguha. Ikorerwa by’umwihariko gukoreshwa mu bitaro kandi ntibiboneka ngo bikoreshwe mu rugo.

Ibitaro bimwe na bimwe bishobora gukoresha ubwoko bwa generic bwa IV liothyronine, ariko byose birimo ibikoresho bikora kimwe kandi bikora kimwe. Itsinda ryawe ry’abaganga rizakoresha ubwoko bwose buboneka mu kigo cyabo.

Uburyo bwo gusimbuza Liothyronine

Mu gihe cy’uburwayi bwa hypothyroidism butari bukomeye, oral levothyroxine (Synthroid, Levoxyl) ni uburyo bwo kuvura busanzwe. Biroroshye gukoreshwa igihe kirekire kandi birashobora gufatwa mu rugo, ariko bifata ibyumweru kugirango bigere ku ngaruka zose.

Mu bihe by’ubutabazi aho IV liothyronine itaboneka, abaganga bamwe bashobora gukoresha IV levothyroxine (Synthroid injection), nubwo ikora gahoro. Mu bihe bidasanzwe, ibicuruzwa bisanzwe bya thyroid bishobora gutekerezwa, ariko ibi ntibiboneka muri IV.

Icyemezo giterwa n’uburyo ubuvuzi bukenewe vuba kandi icyaboneka. IV liothyronine iracyakomeza kuba uburyo bwihuta bwo kuvura ibibazo bya thyroid byukuri, mugihe imiti yo kunywa ari myiza kubuvuzi burambye, burambye.

Ese Liothyronine iruta Levothyroxine?

IV liothyronine na levothyroxine bikora ibintu bitandukanye, bityo kubigereranya ntibisa no kugereranya pome n'amapome. Liothyronine ikora vuba cyane ariko kandi irakomeye kandi ishobora guteza akaga.

Mu bihe by'uburwayi bwihutirwa nka coma ya myxedema, liothyronine ya IV iruta izindi kuko ishobora kurokora ubuzima igihe umuvuduko ari ngombwa. Ariko, mu gusimbuza imisemburo ya thyroid ya buri munsi, levothyroxine yo kunywa ni nziza kandi yizewe.

Tekereza liothyronine ya IV nk'umuti w'ubutabazi bwihutirwa, mu gihe levothyroxine isa n'imiti ya buri munsi yizewe. Abantu benshi bakira liothyronine ya IV bazahindukira bakoreshe levothyroxine yo kunywa mu gihe kirekire.

Icyemezo cyiza giterwa n'uburwayi bwawe. Mu gihe cy'uburwayi bwihutirwa buteje ubuzima akaga, liothyronine ya IV ni nziza. Mu gucunga hypothyroidism ihoraho mu rugo, levothyroxine ni yo nziza.

Ibibazo Bikunze Kubazwa Kuri Liothyronine

Q1. Ese Liothyronine ni nziza ku bantu barwaye indwara z'umutima?

Liothyronine ya IV isaba kwitonda cyane ku bantu barwaye indwara z'umutima kuko ishobora kongera umuvuduko w'umutima n'umuvuduko w'amaraso. Ariko, mu bihe biteje ubuzima akaga, abaganga baracyayikoresha bakoresheje ibikoresho byo gukurikirana umutima.

Niba ufite ibibazo by'umutima, ikipe yawe y'abaganga izatangira n'imiti mike kandi ikurikirane umuvuduko w'umutima wawe buri gihe. Bashobora kandi kuguha imiti yo kurinda umutima wawe mugihe cy'ubuvuzi. Icyemezo giterwa niba icyorezo cya thyroid kirimo akaga kurusha ingaruka z'umutima.

Q2. Nkwiriye gukora iki niba mbonye liothyronine nyinshi?

Kuva liothyronine ya IV itangwa n'abashinzwe ubuzima mu bitaro gusa, kwiyongera kw'imiti ntibakunze kubaho kandi byakwitabwaho ako kanya n'ikipe yawe y'abaganga. Ibimenyetso byo kwiyongera kw'imisemburo ya thyroid birimo umuvuduko w'umutima wihuse cyane, kuribwa cyane mu gituza, cyangwa guhungabana cyane.

Niba kwiyongera kw'imiti bibaye, ikipe yawe y'abaganga izahagarika gutera imiti ako kanya kandi itange ubufasha. Bashobora kuguha imiti yo kugabanya umuvuduko w'umutima wawe kandi bakagukurikirana neza kugeza igihe ingaruka zishirira. Inkuru nziza ni uko liothyronine ya IV ifite igihe gito cyo gukora.

Q3. Ni iki kibaho ninsiba urugero rwa Liothyronine?

Kubera ko Liothyronine ya IV itangwa mu bitaro n'abashinzwe ubuzima, wowe ubwawe ntuzasiba urugero. Itsinda ryawe ry'abaganga rikoresha gahunda ikarishye kandi rigukurikiranira hafi.

Niba habayeho gutinda ku rugero rwawe rwashyizweho kubera impamvu z'ubuvuzi, abaganga bawe bazahindura igihe gishingiye ku buzima bwawe bw'ubu n'urugero rwa hormone. Bashobora gupima amaraso yawe mbere yo gukomeza ku rugero rukurikira.

Q4. Ni ryari nshobora kureka gufata Liothyronine?

Itsinda ryawe ry'abaganga rizafata icyemezo cyo kureka Liothyronine ya IV gishingiye ku rugero rwa hormone ya thyroïde yawe n'imikorere rusange. Ibi bikunda kuba nyuma y'iminsi mike ubuzima bwawe bumaze gushyirwa ku murongo.

Guhindura bikunda gukubiyemo guhindukira ku miti ya thyroïde yo kunywa aho kureka rwose gusimbuza hormone ya thyroïde. Abaganga bawe bazapima amaraso yawe buri gihe kugira ngo barebe ko urugero rwa hormone yawe rukomeza guhagarara muri iki gihe cyo guhindura.

Q5. Nshobora gufata indi miti nkanakira Liothyronine ya IV?

Imiti myinshi irashobora gufatwa neza hamwe na Liothyronine ya IV, ariko imwe irashobora gukenera guhindurwa ku rugero. Imiti igabanya amaraso, imiti ya diyabete, n'imiti y'umutima akenshi bisaba gukurikiranwa no guhindurwa bishoboka.

Itsinda ryawe ry'abaganga rizasuzuma imiti yawe yose kandi rikorereho impinduka zose zikenewe. Bazareba kandi imikoranire ishobora kugira ingaruka ku buryo Liothyronine ikora neza cyangwa ikongera ibyago byo kugira ingaruka ziterwa n'iyo miti. Buri gihe bwire itsinda ryawe ry'ubuzima ku miti yose n'ibyongerera imiti urimo gufata.