Macitentan na tadalafil (inzira yo kunywa)

Opsynvi

Ikiyiko cya Macitentan na Tadalafil gikoresha mu kuvura indwara y'amaraso yo mu mutima (PAH), ari yo kuba amaraso ari hejuru mu mubiri munini utwara amaraso ava ku ruhande rw'iburyo rw'umutima (umutima) ajya mu mwijima. Iyo imiyoboro y'amaraso mito iri mu mwijima igoranye amaraso kuyinyuramo, umutima w'iburyo ugomba gukora cyane kugira ngo utware amaraso ahagije anyura mu mwijima. Ikiyiko cya Macitentan na Tadalafil gikora giturutse ku kwirura kw'iyi miyoboro y'amaraso no kongera amaraso ajya mu mwijima, bigatuma umutima utaruhukira. Ubu butike buhabwa abagore gusa muri gahunda y'abagenerwabikorwa yitwa Macitentan-Containing Products REMS (Risk Evaluation and Mitigation Strategy) program. Abagabo ntibakenera kwinjira muri gahunda ya REMS. Iyi miti iboneka mu buryo bukurikira:

Mu gufata icyemezo cyo gukoresha imiti, ibyago byo gufata iyo miti bigomba guhanurwa n'akamaro izagira. Iki ni icyemezo uzatanga hamwe na muganga wawe. Kuri iyi miti, ibi bikurikira bigomba kwitabwaho: Bwira muganga wawe niba wigeze ugira uburwayi budasanzwe cyangwa ubwoko bw'uburwayi buterwa na iyi miti cyangwa izindi miti. Nanone, bwira umuhanga mu buvuzi ufite izindi ndwara z'ubwoko ubwo aribwo bwose, nko ku biribwa, amabara, ibintu byongera ubuzima bw'ibicuruzwa, cyangwa inyamaswa. Ku bicuruzwa bitagomba kwandikwa, soma witonze ibikubiye ku gipfunyika cyangwa mu bikoresho. Ubushakashatsi bukwiye ntabwo bwakozwe ku isano iri hagati y'imyaka n'ingaruka z'imiti ya macitentan na tadalafil ku bana. Ubuziranenge n'ingaruka nziza ntibyarangiye. Ubushakashatsi bukwiye bwakozwe kugeza ubu ntabwo bwerekanye ibibazo byihariye by'abakuze byabuza ikoreshwa ry'imiti ya macitentan na tadalafil ku bantu bakuze. Nta bushakashatsi buhagije ku bagore bwo kumenya ibyago by'uruhinja mu gihe ukoresha iyi miti mu gihe cyo konsa. Pima inyungu zishoboka ugereranije n'ibyago bishoboka mbere yo gufata iyi miti mu gihe cyo konsa. Nubwo imiti imwe n'imwe idakwiye gukoreshwa hamwe na gato, mu bindi bihe imiti ibiri itandukanye ishobora gukoreshwa hamwe nubwo hariho ikibazo gishobora kubaho. Muri uru rubanza, muganga wawe ashobora kwifuza guhindura umwanya, cyangwa izindi ngamba zishobora kuba ngombwa. Iyo ufashe iyi miti, ni ngombwa cyane ko umuhanga mu buvuzi wawe azi niba ufashe imiti iri hasi. Ibi bikurikira byatoranijwe hashingiwe ku kamaro kabyo kandi si ngombwa ko ari byose. Gukoresha iyi miti hamwe n'imiti ikurikira ntibyemerwa. Muganga wawe ashobora gufata icyemezo cyo kutakugirira iyi miti cyangwa guhindura imiti imwe mu yindi ufashe. Gukoresha iyi miti hamwe n'imiti ikurikira ntibisanzwe byemewe, ariko bishobora gusabwa mu bihe bimwe na bimwe. Niba imiti yombi yanditswe hamwe, muganga wawe ashobora guhindura umwanya cyangwa uko uyikoresha rimwe cyangwa imiti yombi. Imiti imwe n'imwe ntigomba gukoreshwa mu gihe cyo kurya cyangwa hafi yacyo cyangwa kurya ibiryo bimwe na bimwe kuko hariho ikibazo gishobora kubaho. Gukoresha inzoga cyangwa itabi hamwe n'imiti imwe na yo bishobora gutera ikibazo. Ibi bikurikira byatoranijwe hashingiwe ku kamaro kabyo kandi si ngombwa ko ari byose. Gukoresha iyi miti hamwe n'ibikurikira ntibisanzwe byemewe, ariko bishobora kuba bidashoboka kwirinda mu bihe bimwe na bimwe. Niba ikoreshwa hamwe, muganga wawe ashobora guhindura umwanya cyangwa uko uyikoresha, cyangwa akaguha amabwiriza yihariye ku ikoreshwa ry'ibiribwa, inzoga, cyangwa itabi. Gukoresha iyi miti hamwe n'ibikurikira bishobora gutera ibyago byiyongereye by'ingaruka zimwe na zimwe ariko bishobora kuba bidashoboka kwirinda mu bihe bimwe na bimwe. Niba ikoreshwa hamwe, muganga wawe ashobora guhindura umwanya cyangwa uko uyikoresha, cyangwa akaguha amabwiriza yihariye ku ikoreshwa ry'ibiribwa, inzoga, cyangwa itabi. Kuba hari ibindi bibazo by'ubuzima bishobora kugira ingaruka ku ikoreshwa ry'iyi miti. Menya neza kubwira muganga wawe niba ufite ibindi bibazo by'ubuzima, cyane cyane: