Inkingo ya Metoclopramide ni iki: Ibikoreshwa, Urutonde rw'imiti, Ingaruka ziterwa n'iyo miti n'ibindi

Inkingo ya Metoclopramide ni umuti wandikirwa na muganga ufasha kugenzura isesemi rikomeye no kuruka iyo imiti yo kunywa itashoboka cyangwa idakora neza. Ubu bwoko bwo guterwa inshinge butanga umuti mu maraso yawe binyuze mu muyoboro w'imitsi cyangwa guterwa mu mutsi, bigatuma bikoreshwa cyane mu bitaro cyangwa mu bihe by'ubutabazi.

Abaganga bakunda gukoresha inkingo ya metoclopramide iyo abarwayi batabasha gukomeza kunywa imiti yo kunywa kubera kuruka cyane cyangwa iyo hakenewe ubufasha bwihuse. Uyu muti ukora ubuza imbaraga zimwe na zimwe mu bwonko bwawe no mu gihe cyo mu nda bitera isesemi no kuruka.

Inkingo ya Metoclopramide ni iki?

Inkingo ya Metoclopramide ni uburyo bw'amazi bwa metoclopramide butangwa binyuze mu rusinga mu muyoboro wawe (intravenous) cyangwa mu mutsi (intramuscular). Igenewe mu cyiciro cy'imiti yitwa dopamine receptor antagonists, bivuze ko ibuza ibimenyetso by'imiti runaka mu mubiri wawe bishobora gutera isesemi n'ibibazo byo mu nda.

Ubu bwoko bwo guterwa inshinge bukora vuba kuruta ibinini cyangwa ibisubizo byo kunywa kuko binyura mu gihe cyo mu nda yawe rwose. Uyu muti ugera mu maraso yawe mu minota mike, bigatuma bikwiriye mu bihe ubufasha bwihuse ari ngombwa.

Abaganga basanzwe bagenewe metoclopramide yo guterwa inshinge mu gihe gikomeye cyangwa iyo ubundi buryo bw'uyu muti butakwiriye. Uzahabwa ubu buvuzi mu bigo by'ubuvuzi nk'ibitaro, amavuriro, cyangwa ibyumba by'ubutabazi munsi y'ubuyobozi bw'umwuga.

Inkingo ya Metoclopramide ikoreshwa mu iki?

Inkingo ya Metoclopramide ivura ibibazo bitandukanye bijyanye n'isesemi, kuruka, n'ibibazo by'imikorere y'inda. Abaganga bakoresha cyane isesemi rikomeye no kuruka bititabira ubundi buvuzi.

Uyu muti ufasha mu kurwanya isesemi no kuruka biterwa n'uburwayi butandukanye. Ibi birimo imiti ya kanseri, akenshi itera isesemi ikaze ishobora kumara iminsi myinshi. Uyu muti kandi ukoreshwa nyuma yo kubagwa, mu kurwanya isesemi no kuruka nyuma yo kubagwa, cyane cyane iyo abarwayi batabasha gufata imiti yo kunywa.

Rimwe na rimwe, abaganga bakoresha urushinge rwa metoclopramide mu gufasha abarwayi bafite ikibazo cyo gutinda kw'igifu, ubu burwayi igifu gitindamo gusohora ibyo cyariye. Ibi bishobora gutera isesemi ihoraho, kuruka, no kuribwa mu nda. Uru rushinge rufasha imitsi yo mu gifu gukora neza kugira ngo ibyo kurya binyure mu nzira yo mu gifu.

Mu bihe by'ubutabazi, abaganga bashobora gukoresha uyu muti mu kurwanya isesemi ikaze mu gitondo ku bagore batwite, iyo izindi miti itagize icyo itanga kandi ubuzima bw'umubyeyi buri mu kaga. Ariko, iyi mikoreshereze isaba gusuzuma neza inyungu n'ingaruka zishobora kuvuka.

Uko urushinge rwa Metoclopramide rukora

Uru rushinge rwa metoclopramide rukora mu guhagarika imikorere ya dopamine mu duce tubiri tw'ingenzi tw'umubiri wawe. Ufatwa nk'umuti ukomeye wo kurwanya isesemi ushobora gutanga ubufasha bukomeye iyo izindi miti itagize icyo itanga.

Mu bwonko bwawe, uyu muti uhagarika ibimenyetso mu gace ka chemoreceptor trigger zone, gakora nk'«ikigo cy'isesemi» mu mubiri wawe. Iyo aka gace kabonye imisemburo cyangwa uburozi runaka, bisanzwe bitera kuruka kugira ngo bikurinde. Metoclopramide ihagarika ibi bimenyetanyo, igabanya kumva isesemi no kugira irari ryo kuruka.

Uyu muti kandi ukora mu buryo butaziguye mu nzira yo mu gifu, uhagarika imikorere ya dopamine mu gifu no mu mara. Ibi bifasha imitsi yo mu gifu gukorana neza, ituma ibyo kurya binyura mu nzira yo mu gifu ku muvuduko usanzwe.

Byongeye kandi, metoclopramide yongera irekurwa rya acetylcholine, umusemburo ufasha guhuza imikorere y'imitsi mu nzira yo mu gifu. Iyi mikorere ibiri ituma uyu muti ukora neza mu kurwanya isesemi n'ibibazo byo mu gifu.

Nkwakira Urumogi rwa Metoclopramide?

Urumogi rwa Metoclopramide rutangwa buri gihe n'abantu bafite ubumenyi mu by'ubuzima mu bigo by'ubuvuzi. Ntabwo wowe ubwawe uzitera uyu muti, kuko bisaba ibikoresho by'ubuvuzi bikwiye no kugenzura.

Urukingo rushobora gutangwa mu buryo bubiri: mu maraso (mu urukururuku) cyangwa mu misitsi (mu misitsi). Umuganga wawe azahitamo uburyo bwiza bushingiye ku miterere yawe yihariye n'ibyo ukeneye mu by'ubuvuzi. Gutanga urumogi mu maraso mubisanzwe bikora vuba, mugihe urukingo rwo mu misitsi rushobora gukoreshwa mugihe kubona urukururuku bigoye.

Mbere yo kwakira urukingo, menyesha ikipe yawe y'ubuvuzi ku bijyanye n'imiti urimo gufata, harimo imiti itangwa itagomba kwandikwa na muganga n'ibyongerera imbaraga. Imwe mu miti irashobora gukururana na metoclopramide, bityo aya makuru afasha kurengera umutekano wawe.

Ntabwo ukeneye gutegura ibintu byihariye mbere yo kwakira urukingo rwa metoclopramide. Bitandukanye n'imiti yo kunywa, ntugomba guhangayika no kuyifata hamwe n'ibiryo cyangwa ku gifu cyambaye ubusa kuko yirengagiza rwose sisitemu yawe yo mu gifu.

Nzakoresha Urumogi rwa Metoclopramide Igihe Kingana Gite?

Igihe cyo kuvura urumogi rwa metoclopramide giterwa n'uburwayi bwawe bwihariye n'uburyo witwara neza ku muti. Ubuvuzi bwinshi buri mu gihe gito, bumara iminsi mike kugeza ku byumweru bike.

Kubera isesemi no kuruka nyuma yo kubagwa, ushobora guhabwa urukingo rumwe cyangwa ebyiri mu munsi umwe cyangwa ibiri. Isesemi ikomoka kuri chimiothérapie irashobora gusaba inkingo muminsi myinshi mugihe cyo kuvurwa, bitewe n'igihe cyawe cya chimiothérapie.

Abaganga muri rusange bagerageza kugabanya ikoreshwa rya metoclopramide kugeza ku gihe gito gishoboka. Gukoresha igihe kirekire birashobora kongera ibyago byo kugira ingaruka zikomeye, cyane cyane indwara zo kwimuka zishobora guhinduka zihoraho mu bihe bidasanzwe.

Itsinda ryawe ry'abaganga rizakurikirana uko witwara ku miti kandi rihindure igihe uzayimara ukurikije uko bimeze. Bazanakora kugira ngo bagushyire ku miti yo kunywa cyangwa izindi miti vuba bishoboka igihe ubuzima bwawe buzaba bubyemeye.

Ni Ibihe Bikorwa Bigaragara ku Miti ya Metoclopramide?

Umuti wa metoclopramide ushobora gutera ibikorwa bitandukanye, kuva ku boroheje kugeza ku bikomeye. Abantu benshi bakira neza uyu muti, ariko ni ngombwa kumenya ibyo ugomba kwitaho mugihe uvurwa.

Ibikorwa bisanzwe bigaragara abantu benshi bahura nabyo birimo gusinzira cyane, kunanirwa, no kutagira umutuzo. Ushobora kandi kubona kubabara umutwe, kuribwa umutwe, cyangwa kumva ufite ubwoba cyangwa uhagaritse umutima. Ibi bikorwa mubisanzwe biragenda bigabanuka umubiri wawe umaze kumenyera umuti.

Abantu bamwe bahura n'ibikorwa bigaragara mu igogora nubwo umuti utangwa mu nshinge. Ibi bishobora kwirimo kuruka, guhagarara kw'amazi mu mubiri, cyangwa kutumva neza mu nda. Akanwa gakama no guhinduka kw'uburyohe nabyo birashoboka.

Ibikorwa bigaragara bikomeye birimo ibibazo byo kwimuka, bishobora kugaragara nyuma y'amasaha cyangwa iminsi yo kuvurwa. Ibi birimo gukomera kw'imitsi, guteguka, cyangwa kwimuka kw'imitsi ku buryo butunguranye, cyane cyane mu maso, mu ijosi, cyangwa mu maboko. Niba ubonye imyitwarire idasanzwe, bimenyeshe umuganga wawe ako kanya.

Ibikorwa bidasanzwe ariko bikomeye birimo tardive dyskinesia, uburwayi burimo kwimuka kenshi, ku buryo butunguranye bushobora guhinduka burundu. Iki kigereranyo cyiyongera mugihe cyo kuvurwa kirekire n'imiti myinshi, niyo mpamvu abaganga bagabanya ikoreshwa rya metoclopramide mugihe bishoboka.

Gahoro cyane, abantu bamwe bashobora guhura na neuroleptic malignant syndrome, uburwayi butera ubuzima kwibazaho burimo umuriro mwinshi, gukomera kw'imitsi, no kuvurungana. Ibi bisaba ubufasha bwihutirwa bw'abaganga.

Ni Bande Batagomba Gufata Metoclopramide?

Abantu bamwe na bamwe bagomba kwirinda guterwa urushinge rwa metoclopramide kubera kwiyongera kw'ibibazo. Muganga wawe azasuzuma neza amateka yawe y'ubuzima mbere yo kugusaba ubu buvuzi.

Abantu bafite amateka y'indwara zo mu ngingo, harimo indwara ya Parkinson, muri rusange bagomba kwirinda metoclopramide. Uyu muti urashobora gukomeza ibi bibazo cyangwa kubangamira imiti yabo. Kimwe n'abafite amateka ya tardive dyskinesia ntibagomba guhabwa metoclopramide.

Niba ufite ibibazo bimwe na bimwe byo mu gifu cyangwa mu mara, metoclopramide irashobora kutagukwira. Ibi birimo kubangamirwa kw'amara, gucukuka, cyangwa kuva amaraso mu nzira yawe yo mu gifu. Ibyo uyu muti ukora ku misitsi yo mu gifu byashobora gukomeza ibi bibazo.

Abantu bafite pheochromocytoma, igituntu giteye ubwoba cyane cyane cy'ingirangingo zifasha umubiri gukora imisemburo, bagomba kwirinda metoclopramide kuko ishobora gutera izamuka ry'umuvuduko w'amaraso. Abafite indwara zo gufatwa n'ibicurane nabo bashobora gukenera kwirinda uyu muti, kuko ushobora kugabanya urugero rwo gufatwa n'ibicurane.

Abageze mu zabukuru bahura n'ibibazo byinshi byo ku ruhande, cyane cyane indwara zo mu ngingo, bityo abaganga bakoresha ubushishozi bwinshi mugihe batekereza metoclopramide kubantu bakuze.

Amazina y'ubwoko bwa metoclopramide

Urushinge rwa metoclopramide ruboneka munsi y'amazina menshi y'ubwoko, aho Reglan ariyo izwi cyane. Andi mazina y'ubwoko arimo Metozolv ODT, nubwo ibi byerekeye urupapuro rwo kunywa.

Ibitaro byinshi na za clinique bikoresha ubwoko bwa metoclopramide, burimo ibintu bimwe bikora kandi bikora neza nk'ubwoko bw'amazina. Imiti rusange icamo ibizamini bimwe byo kugenzura umutekano n'ubushobozi.

Muganga wawe azahitamo uburyo bwihariye bushingiye ku kuboneka, ibyo ukeneye mu buvuzi, n'ubwishingizi. Ubwoko bwose bwa metoclopramide bwemewe na FDA buhura n'ubuziranenge bumwe n'amabwiriza y'umutekano.

Uburyo bwo gusimbuza urushinge rwa metoclopramide

Hari ubundi buryo bwo kuvura isesemi no kuruka ushobora gukoresha aho gukoresha urushinge rwa metoclopramide. Umuganga wawe ashobora gutekereza kuri izi nzira bitewe n'uko ubuzima bwawe bumeze n'amateka yawe y'ubuvuzi.

Urushinge rwa Ondansetron ni uburyo busanzwe bukoreshwa, cyane cyane ku isesemi iterwa na kanseri. Ikora mu buryo butandukanye na metoclopramide mu guhagarika imyakura ya serotonin aho guhagarika imyakura ya dopamine. Uyu muti ntugira ingaruka zifitanye isano no kugenda ariko ushobora kutagira akamaro ku bibazo byo mu nda.

Urushinge rwa Promethazine ni ubundi buryo, cyane cyane ku ndwara yo mu ngendo cyangwa isesemi rusange. Iherereye mu cyiciro cy'imiti itandukanye yitwa antihistamines kandi ishobora no gufasha mu guhangayika no kuruhuka.

Ku bijyanye na gastroparesis by'umwihariko, domperidone ishobora kuba ubundi buryo mu bihugu bimwe na bimwe, nubwo itaboneka cyane muri Leta Zunze Ubumwe z'Amerika. Erythromycin, akenshi ari antibiyotike, ishobora no gufasha mu gusukura mu nda bitewe n'ingaruka zayo ku mikoranire y'imitsi yo mu igogora.

Uburyo butari ubw'imiti nka acupressure, ibiyobyabwenge bya ginger, cyangwa impinduka mu mirire na byo bishobora gufasha ku isesemi, nubwo ibi bikoreshwa hamwe aho gukoreshwa mu mwanya w'imiti mu gihe cy'indwara zikomeye.

Ese urushinge rwa Metoclopramide ruruta Ondansetron?

Urushinge rwa Metoclopramide n'urushinge rwa ondansetron buri kimwe gifite inyungu zihariye, kandi nta na kimwe kiruta ikindi. Guhitamo biterwa n'ubuzima bwawe bwihariye n'icyateye isesemi yawe.

Metoclopramide itanga inyungu yo gufasha ku isesemi no ku bibazo byo mu nda. Niba isesemi yawe ifitanye isano no gusukura mu nda cyangwa gastroparesis, metoclopramide ishobora kugira akamaro kurushaho kuko ikemura ikibazo aho guhagarika ibimenyetso by'isesemi.

Ondansetron akenshi itera ingaruka nke zijyanye n'imitsi kandi akenshi ikoreshwa cyane mu kurwanya isesemi iterwa na kanseri. Ifasha cyane mu gukumira isesemi no kuruka biterwa n'imiti ivura kanseri kandi akenshi irakara mu gihe ikoreshwa igihe kirekire.

Abaganga bakunda gusuzuma imyaka yawe, amateka yawe y'ubuzima, n'icyateye isesemi yawe mbere yo guhitamo imiti. Abarwayi bakiri bato bafite gastroparesis bashobora kungukirwa cyane na metoclopramide, naho abarwayi bakuze cyangwa abakira imiti ya kanseri bashobora gukoresha neza ondansetron.

Ibikunze Kubazwa Kuri Metoclopramide Injection

Ese Metoclopramide Injection irakara ku barwayi ba diyabete?

Metoclopramide injection ishobora gufasha abantu barwaye diyabete bafite gastroparesis, ikibazo gikunze kugaragara aho igifu gitinda gusohora ibyo kirimo. Iki kibazo gishobora gutuma kugenzura isukari mu maraso bigorana kuko imitsi yo mu gifu itangira gukora nabi.

Ariko, uyu muti ushobora kugira ingaruka ku isukari mu maraso ya bamwe. Bishobora gutuma isukari yawe mu maraso izamuka cyangwa igabanuka, bityo umuganga wawe azagenzura urugero rwa glucose yawe mu gihe uvurwa. Ushobora gukenera guhindura imiti yawe ya diyabete cyangwa doze ya insuline.

Uburyo bwo guterwa inshinge burinda ibibazo bishobora guterwa n'imitsi yo mu gifu, bituma bikoreshwa cyane ku barwayi ba diyabete bafite gastroparesis ikomeye batabasha kumira imiti yo kunywa.

Nigute nzakora niba ngize allergie kuri Metoclopramide Injection?

Kubera ko metoclopramide injection itangwa mu bigo by'ubuvuzi, abaganga bashobora guhita bamenya kandi bagavura allergie. Ibimenyetso bya allergie birimo guhumeka bigoye, kubyimba mu maso cyangwa mu muhogo, uruhu rurya cyane, cyangwa umutima utera vuba.

Niba ubonye kimwe muri ibi bimenyetso, bimenyeshe ikipe yawe y'ubuzima ako kanya. Bazahagarika urukingo kandi batange ubuvuzi bukwiye, bushobora kuba burimo imiti irwanya allergie, imiti ya corticoïdes, cyangwa indi miti yihutirwa.

Mbere yo guterwa urukingo rwa metoclopramide, bimenyeshe umuganga wawe ibyerekeye allergie wigeze kugira ku miti, cyane cyane niba waragize ibibazo bya metoclopramide cyangwa imiti isa nayo mu gihe cyashize.

Nkwiriye gukora iki niba nciweho urukingo rwa metoclopramide rwari rwatanzwe?

Kubera ko urukingo rwa metoclopramide rutangwa n'abantu b'inzobere mu by'ubuzima mu bigo by'ubuvuzi, ntuzacikanwa n'urukingo ku giti cyawe. Ikipe yawe y'ubuzima icunga gahunda yawe yo gutanga imiti kandi izakora ibishoboka byose kugira ngo wakire imiti nk'uko yategetswe.

Niba uteganyirijwe guterwa urukingo rw'abarwayi batari mu bitaro kandi ntushobore kugera ku gihe, vugana n'ibiro by'umuganga wawe vuba na bwangu. Bashobora kongera gutegura uburyo bwo kuvurwa kwawe cyangwa gutanga ubuyobozi ku bijyanye no gucunga ibimenyetso byawe kugeza igihe ushobora guterwa urukingo.

Ntugerageze "gukora ibyo wacikanwe" usaba doze zinyongera niba wacikanwe no kuvurwa kwari kwateganyijwe. Umuganga wawe azagena uburyo bwiza bushingiye ku bimenyetso byawe by'ubu n'uburwayi bwawe.

Nshobora guhagarika ryari guterwa urukingo rwa metoclopramide?

Umuganga wawe azagena igihe bizaba byemewe guhagarika urukingo rwa metoclopramide hashingiye ku bimenyetso byawe n'uburwayi bw'ibanze. Abantu benshi ntibakeneye kugabanya doze buhoro buhoro kuko imiti iterwa mu nshinge ikunze kuba y'igihe gito.

Ushobora guhagarika guterwa inshinge igihe isesemi n'umuriro byawe byiyongereye bihagije ku buryo wafata imiti yo kunywa, cyangwa igihe icyateye ibimenyetso byawe gikize. Urugero, isesemi nyuma yo kubagwa ikunze gukira mu minsi mike nyuma yo kubagwa.

Ntuzigere uhagarika kuvurwa mbere y'igihe utabiganiriyeho n'umuganga wawe, kabone n'iyo wumva umeze neza. Uburwayi bumwe na bumwe busaba uburyo bwuzuye bwo kuvurwa kugira ngo birinde gusubira kw'ibimenyetso.

Nshobora gutwara imodoka nyuma yo guterwa urushinge rwa Metoclopramide?

Ntabwo ugomba gutwara imodoka cyangwa gukoresha imashini ako kanya nyuma yo guterwa urushinge rwa metoclopramide. Uyu muti ushobora gutera gusinzira, isereri, n'ibibazo byo kwimuka bishobora kugutera kutabasha gutwara neza.

Teganya ko hari umuntu uzakujyana mu rugo nyuma yo guterwa urushinge, cyane cyane niba ari ubuvuzi bwawe bwa mbere cyangwa niba warigeze kugira ingaruka mbere. Izi ngaruka zirashobora kumara amasaha menshi nyuma yo guterwa urushinge.

Umaze kugera mu rugo kandi wumva umeze neza, urashobora gukomeza buhoro buhoro ibikorwa bisanzwe uko ubishoboye. Niba ukomeje kumva usinzira, ugira isereri, cyangwa ubona imyitwarire idasanzwe, irinda gutwara imodoka kugeza igihe izi ngaruka zose zikize rwose.