Midazolam ni iki: Ibyo ikoreshwa, urugero rwo gufata, ingaruka ziterwa n'iyo miti n'ibindi

Midazolam ni umuti wandikirwa na muganga wo mu cyiciro cy'imiti yitwa benzodiazepines, ikora igabanya ubwonko bwawe n'imitsi. Ushobora kuyimenya neza nk'umuti utuza abantu ukoreshwa na muganga kugirango agufashe kuruhuka mbere yo gukorerwa ibizamini by'ubuvuzi cyangwa kuvura impungenge zikabije no gufata imitsi. Uyu muti ni ingufu kandi bisaba ko ugomba gukurikiranwa na muganga, ariko iyo ukoreshejwe neza, ushobora gutanga ubufasha bukomeye kubibazo byihariye.

Midazolam ni iki?

Midazolam ni umuti wa benzodiazepine ukora mu gihe gito ugira ingaruka ku mikorere y'imirasire mu bwonko bwawe kugirango ugire ingaruka zo gutuza. Yagenewe gukora vuba kandi igashira vuba ugereranije n'indi miti yo mu cyiciro kimwe. Tekereza nk'inzira yoroheje ariko ifite akamaro yo gufasha imitsi yawe kugabanya umuvuduko wayo iyo irenga urugero.

Uyu muti uza mu buryo butandukanye, burimo ibinini bifatirwa mu kanwa, amazi, n'ibinyabutabuzi. Uburyo bwose bugenewe ibibazo by'ubuvuzi byihariye kandi burahora butangwa na abaganga bazi ibyo ukeneye. Muganga wawe azahitamo uburyo bukwiye hashingiwe ku bibazo ufite n'amateka yawe y'ubuvuzi.

Midazolam ikoreshwa mu iki?

Midazolam ifite intego nyinshi z'ubuvuzi z'ingenzi, cyane cyane ifasha abantu bakeneye ubufasha bwihuse ku mpungenge cyangwa gutuzwa mbere yo gukorerwa ibizamini. Muganga wawe ashobora kuyandika iyo izindi nshuti zitatanze ubufasha buhagije cyangwa iyo ukeneye ingaruka zo gutuza ako kanya.

Dore ibibazo by'ingenzi aho midazolam yerekana ko ifite akamaro:

• Impungenge mbere yo gukorerwa ibizamini no gutuzwa mbere yo kubagwa cyangwa ibizamini by'ubuvuzi
• Ibihe by'impungenge zikabije bikeneye ubufasha bwihuse
• Status epilepticus (gufatwa kw'imitsi bikomeye bitahagarara byonyine)
• Kutabona ibitotsi mu bitaro aho gusinzira ari ngombwa kugirango umuntu akire
• Ibimenyetso byo kuva ku nzoga munsi y'ubuyobozi bwa muganga

Mu buryo butajyenda cyane, abaganga bashobora gukoresha midazolam mu bindi bihe byihariye nk'ubufasha mu guhosha umujinya ukabije cyangwa nk'igice cy'amabwiriza yo kubaga. Umuganga wawe azahora apima inyungu zihwanye n'ibishobora guteza akaga mu bihe byawe byihariye.

Midazolam ikora ite?

Midazolam ikora yongera ingaruka z'imiti kamere mu bwonko bwawe yitwa GABA, ifasha gutuza imikorere y'imitsi. Iyo GABA itagikora neza ku giti cyayo, midazolam yinjira kugira ngo yongere ibimenyetso byayo bituza mu rwungano rwawe rw'imitsi.

Uyu muti ufatwa nk'ukomeye cyane mu muryango wa benzodiazepine, bivuze ko utanga ingaruka zikomeye vuba na bwangu. Ubusanzwe uzatangira kumva ingaruka zayo zituje mu minota 15 kugeza kuri 30 umaze kuyifata mu kanwa. Uyu muti ugera ku ngaruka zayo zikomeye mu isaha imwe kugeza ku masaha 2 kandi ubusanzwe ugenda mu masaha 6 kugeza kuri 8.

Kubera ko midazolam ikora neza cyane, yashyizwe mu cyiciro cy'ibintu bigenzurwa. Ibi bivuze ko muganga wawe azagenzura ikoreshwa ryawe neza kugira ngo yemeze ko urimo kubona inyungu zikwiye mugihe ugabanya ibishobora guteza akaga.

Nkwiriye gufata midazolam nte?

Gufata midazolam neza ni ngombwa haba ku mutekano no ku gikorwa cyayo. Jya ukurikiza amabwiriza yihariye ya muganga wawe, kuko bageneye urugero n'igihe cyo gufata ku byo ukeneye n'uburwayi bwawe.

Ku miti ifatirwa mu kanwa, urashobora gufata midazolam hamwe cyangwa udafite ibiryo, nubwo kuyifata hamwe n'ifunguro rito rishobora gufasha kugabanya umujinya wo mu gifu niba wumva ubikunda. Irinde inzoga rwose mugihe ufata uyu muti, kuko guhuza bishobora guteza akaga. Niba wandikiwe umuti w'amazi, koresha igikoresho cyo gupima cyatanzwe na farumasi yawe kugira ngo upime neza.

Gena umuti wa midazolam ahantu hatekanye kandi heza ushobora kuruhukiramo. Ntuzatware imodoka, ntuzakoreshe imashini, cyangwa ngo ufate ibyemezo bikomeye by'ingenzi byibuze amasaha 8 umaze kuwufata. Kugira inshuti yizewe cyangwa umuntu wo mu muryango wawe hafi yawe akenshi bifasha, cyane cyane ku gipimo cyawe cya mbere.

Nzamara Igihe Kingana Giki Nda Midazolam?

Midazolam akenshi yandikirwa gukoreshwa igihe gito, akenshi iminsi mike kugeza ku byumweru bibiri byinshi. Muganga wawe akora ubu buryo kuko umubiri wawe ushobora kwihanganira umuti, bivuze ko ushobora gukenera ibipimo byinshi uko igihe kigenda kugirango ugere ku ngaruka zimwe.

Kubijyanye no guhangayika mbere yo gukora ibizamini, akenshi uzanywa urugero rumwe mbere yo kujya kwa muganga. Kubindi bibazo nk'ihungabana rikomeye cyangwa ibibazo byo gusinzira, muganga wawe ashobora kuwandikira iminsi 3 kugeza kuri 7 mugihe akora ku bisubizo byo kuvura igihe kirekire.

Ntuzigera uhagarika gufata midazolam ako kanya niba wari umaze kuyikoresha buri gihe, kabone niyo byaba byaramaze icyumweru kimwe cyangwa bibiri. Muganga wawe azakora gahunda yo kugabanya buhoro buhoro kugirango yirinde ibimenyetso byo kuva mu muti, bishobora harimo guhangayika kwiyongera, kutagira umutuzo, kandi mu bihe bidasanzwe, gufatwa.

Ni Ibihe Bikorwa Bigaragara Bya Midazolam?

Kimwe n'imiti yose, midazolam irashobora gutera ingaruka zigaragara, nubwo abantu benshi bayihanganira neza iyo ikoreshwa nkuko byategetswe. Kumva icyo witegura birashobora kugufasha kumva ufite icyizere cyinshi kubijyanye n'ubuvuzi bwawe kandi ukamenya igihe wahamagara umuganga wawe.

Ingaruka zigaragara cyane ushobora guhura nazo zirimo:

• Gusinzira no kunanirwa bishobora kumara amasaha menshi
• Kuribwa umutwe cyangwa kumva udashikamye ku birenge byawe
• Urujijo cyangwa kugorana kwibanda
• Kuribwa umutwe cyangwa kumva "gisa n'igihu" umunsi ukurikira
• Isesemi cyangwa kuribwa mu nda
• Umunwa wumye cyangwa impinduka mu buryohe

Ibi byangiza akenshi biroroshye kandi ntibiramba, bigenda bikemuka igihe umuti uva mu mubiri wawe. Ariko, abantu bamwe bahura n'ingaruka zikomeye zikeneye ubufasha bwihutirwa bw'abaganga.

Vugana n'umuganga wawe ako kanya niba ubonye izi ngaruka zikomeye:

• Urubwa rukabije rutuma bigoye kubyuka
• Kugihumeka gake cyangwa gito
• Urujijo rukabije cyangwa ibibazo byo kwibuka
• Impinduka zidasanzwe z'imitekerereze cyangwa imyitwarire y'urugomo
• Urugero rw'ibimenyetso by'uburwayi nka gusa, kubyimba, cyangwa guhumeka bigoye

Gake, abantu bamwe bahura n'ingaruka zidasanzwe aho barushaho guhangayika cyangwa guhagarika umutima aho gutuza. Ibi bibaho ku bantu batarenga 1% ariko bisaba isuzuma ryihutirwa ry'abaganga niba bibaye.

Ninde Utagomba Gufata Midazolam?

Midazolam ntabwo ikwiriye kuri buri wese, kandi umuganga wawe azasuzuma neza amateka yawe mbere yo kuyandika. Ibyiciro bimwe na bimwe n'ibihe bituma uyu muti ushobora kuba mubi cyangwa utagira akamaro.

Ntabwo ugomba gufata midazolam niba ufite:

• Ibibazo bikomeye byo guhumeka cyangwa apnea yo gusinzira
• Indwara ikomeye y'umwijima cyangwa kunanirwa kw'umwijima
• Myasthenia gravis (uburwayi bwo kunanirwa kw'imitsi)
• Allergies zizwi kuri benzodiazepines
• Glaucoma ya angle ifunganye
• Ubusinzi bw'inzoga cyangwa ibiyobyabwenge

Umuganga wawe azakoresha kandi ubushishozi bwihariye niba ushaje, utwite, wonka, cyangwa ufite ibibazo by'impyiko, agahinda, cyangwa amateka yo gukoresha ibiyobyabwenge. Ibi bihe ntibigutera guhagarika gukoresha midazolam, ariko bisaba gukurikiranwa byihariye kandi bishobora guhindura urugero rwo gufata imiti.

Amazina ya Midazolam

Midazolam iboneka munsi y'amazina menshi y'ubwoko, nubwo verisiyo rusange ikora neza. Izina risanzwe ry'ubwoko ushobora guhura naryo ni Versed, ikoreshwa kenshi mu bitaro no mu mavuriro.

Izindi nshuti z'izina zirimo Dormicum na Hypnovel, nubwo izi zikoreshwa cyane hanze ya Leta Zunze Ubumwe z'Amerika. Farumasi yawe ishobora kubika izi verisiyo zose, kandi zose zikubiyemo ibintu bikora kimwe bifite ingaruka zimwe n'umutekano umwe.

Izindi nzira za Midazolam

Niba midazolam itagukwiriye, imiti myinshi isimbura ishobora gutanga inyungu zisa n'izo mu guhangayika no gutuza. Muganga wawe ashobora gutekereza ku zindi benzodiazepines nka lorazepam (Ativan) cyangwa diazepam (Valium), zikora kimwe ariko zifite igihe gito cyo gukora.

Kubijyanye no gucunga guhangayika igihe kirekire, ibindi bishoboka bitari benzodiazepine birimo buspirone, imiti imwe yo kurwanya depression, cyangwa beta-blockers. Izi nzira zishobora kugira ibyago bike byo kwishingikiriza ariko bishobora gutwara igihe kirekire kugirango bigaragare. Kubijyanye n'ibibazo byo gusinzira, imiti nka zolpidem (Ambien) cyangwa trazodone birashobora gukwiriye gukoreshwa buri gihe.

Umuvuzi wawe azagufasha gushakisha izi nzira zishingiye ku bimenyetso byawe byihariye, amateka yawe y'ubuvuzi, n'intego zo kuvura.

Ese Midazolam iruta Lorazepam?

Midazolam na lorazepam ni benzodiazepines zikora neza, ariko zifite imbaraga zitandukanye zituma buri imwe ikwiriye neza mu bihe byihariye. Guhitamo “kuruta” biterwa rwose n'ibyo ukeneye n'imibereho yawe y'ubuvuzi.

Midazolam ikora vuba kandi ifite igihe gito, bituma ikwiriye cyane guhangayika mbere yo gukora cyangwa ibihe ukeneye ubufasha bwihuse butazamara umunsi wose. Lorazepam itwara igihe kirekire kugirango ikore ariko imara igihe kirekire, ibyo bishobora kuba byiza mu gucunga guhangayika cyangwa ibibazo byo gusinzira.

Muganga wawe azirikana ibintu nko uko ukeneye ubufasha bwihuse, igihe ukeneye ko ingaruka zimara, imiti yawe yindi, n'ubuzima bwawe muri rusange mugihe uhitamo hagati yizi nzira. Imiti yombi ikora neza mugihe ikoreshejwe neza mubihe bikwiye.

Ibikunze Kubazwa Kuri Midazolam

Ese Midazolam irakwiriye abarwayi bakuze?

Midazolam ishobora kuba umutekano ku bantu bakuze, ariko abaganga basanzwe bandika imiti ifite urugero ruto kandi bagakurikiranira hafi. Iyo tugenda dusaza, imibiri yacu itunganya imiti mu buryo butandukanye, kandi abantu bakuze bafite ubushobozi bwo kumva neza ingaruka zo gutuza kandi bashobora kugira ibyago byinshi byo kugwa cyangwa kuvurungana.

Umuvuzi wawe azatangira n'urugero ruto rukora kandi ashobora guhitamo imiti isimbura niba urengeje imyaka 65. Kugenzura buri gihe bifasha kumenya neza ko urimo kubona inyungu utagira ingaruka zikomeye.

Nkwiriye gukora iki niba nanyoye midazolam nyinshi ku buryo butunguranye?

Niba ucyeka ko wanyoye midazolam nyinshi, shakisha ubufasha bwihuse bw'ubuvuzi cyangwa uhamagare abaganga b'uburozi. Ibimenyetso byo kurenza urugero birimo gusinzira cyane, kuvurungana, guhumeka gahoro, no kubura ubufatanye.

Ntugerageze kwisukisha cyangwa utegereze kureba niba ibimenyetso bigenda neza. Abaganga bashobora gutanga ubufasha kandi, niba bibaye ngombwa, bakagutera flumazenil, umuti ushobora guhindura ingaruka za midazolam.

Nkwiriye gukora iki niba nciwe urugero rwa midazolam?

Niba waciwe urugero rwa midazolam, nywa ako kanya wibuka, keretse igihe cyegereye urugero rwawe ruteganyijwe. Ntukigere unywa urugero rwa kabiri icyarimwe kugirango usimbure urugero waciwe, kuko ibi byongera ibyago byo kugira ingaruka.

Kubera ko midazolam akenshi yandikwa gukoreshwa igihe gito cyangwa ibihe bidasanzwe, gucikwa urugero ntibishobora kuba ikibazo. Vugana n'umuvuzi wawe niba utazi icyo gukora cyangwa niba gucikwa urugero bigira ingaruka ku bimenyetso byawe.

Nshobora kureka kunywa midazolam ryari?

Ushobora kureka kunywa midazolam igihe umuvuzi wawe yemeje ko bikwiye, akenshi ni nyuma yuko ibimenyetso byawe bigenda neza cyangwa igihe cyo kuvurwa kwawe kirangiye. Gukoresha igihe gito cyane (urugero rwake), ushobora gushobora kureka utagabanya.

Niba umaze iminsi myinshi ufata midazolam buri gihe, muganga wawe azagushyiriraho gahunda yo kugabanya buhoro buhoro kugira ngo wirinde ibimenyetso byo kuva mu biyobyabwenge. Ntukigere uhagarara ako kanya utabanje kubisobanurira muganga, kabone n'iyo wumva umeze neza.

Ese nshobora gutwara imodoka nyuma yo gufata Midazolam?

Oya, ntugomba gutwara imodoka cyangwa gukoresha imashini mu gihe kitarenze amasaha 8 nyuma yo gufata midazolam, kandi bikaba byakwiyongera niba ukigaragaza ibimenyetso byo gusinzira cyangwa kutumva neza. Uyu muti ugira ingaruka zikomeye ku buryo umubiri wawe witwara, imikorere yawe, n'ubushobozi bwo gufata ibyemezo.

Teganya uburyo bwo kugenda butandukanye mbere yo gufata urugero rwawe, kandi ugire umuntu uhari wo kukugenda niba bibaye ngombwa. Umutekano wawe n'umutekano w'abandi bari mu muhanda ni iby'ingenzi igihe uyu muti uri mu mubiri wawe.