Icyo Olanzapine-na-Samidorphan ari cyo: Ibikoreshwa, Urutonde rw'imiti, Ingaruka ziterwa n'iyo miti n'ibindi

Olanzapine-na-samidorphan ni umuti uvanga ibintu byinshi ufasha kuvura indwara ya schizophrénie na bipolar disorder mu gihe ugabanya ibiro byiyongera bisanzwe bifitanye isano na olanzapine yonyine. Ubu buryo bushya buvanga inyungu zigaragara zo mu mutwe za olanzapine na samidorphan, ifasha kurwanya imbaraga za olanzapine zo gutuma umuntu abyibuha cyane.

Ushobora kumenya uyu muti ku izina ry'ubucuruzi rya Lybalvi, ryakozwe by'umwihariko kugira ngo rikore ku ngaruka zimwe na zimwe zikomeye zo kuvurwa kwa antipsychotique gakondo. Ubu buryo buha icyizere abantu bakeneye imiti ifatika yo mu mutwe ariko bifuza kugabanya impinduka zitifuzwa z'ibiro.

Icyo Olanzapine-na-Samidorphan ari cyo?

Olanzapine-na-samidorphan ni umuti wandikirwa na muganga uvanga ibintu bibiri bikora mu gipimo kimwe. Olanzapine ni mu cyiciro cy'imiti yitwa atypical antipsychotics, mu gihe samidorphan ari umuti urwanya opioid receptor ufasha kugabanya ibiro byiyongera.

Ubu buryo bukorera mu kureka olanzapine ikora akazi kayo ko gutunganya imikorere y'ubwonko mu gihe samidorphan ifunga ibice bimwe na bimwe byakira bifasha kongera ubushake bwo kurya no kongera ibiro. Ubu buryo buhagarariye iterambere rikomeye mu miti yo mu mutwe, ikemura ibimenyetso byo mu mutwe n'impungenge z'imibereho myiza.

Muganga wawe ashobora gutekereza kuri ubu buryo niba warabonye ibisubizo byiza na olanzapine ariko ukagira ibibazo byo kongera ibiro, cyangwa niba utangiye kuvurwa kandi ushaka kugabanya iyi ngaruka yihariye kuva mu ntangiriro.

Icyo Olanzapine-na-Samidorphan ikoreshwa

Uyu muti uvanga ibintu byinshi uvura indwara ebyiri zikomeye zo mu mutwe: schizophrénie na bipolar I disorder. Kubera schizophrénie, ifasha gucunga ibimenyetso nk'ibitekerezo, ibitekerezo by'ubuyobe, no gutekereza bitunganye bishobora kugira ingaruka zikomeye ku buzima bwawe bwa buri munsi.

Muri bipolar I disorder, imiti ifasha guhosha ibihe by'amarangamutima, cyane cyane ibihe by'uburwayi bwo mu mutwe cyangwa ibivanzemo bishobora kurimo amarangamutima yiyongereye, imbaraga ziyongereye, no guciraho iteka. Irashobora gukoreshwa yonyine cyangwa hamwe n'izindi miti igabanya amarangamutima, bitewe n'ibyo ukeneye.

Umuvuzi wawe azagena niba iyi mvange ikwiriye kuri wowe hashingiwe ku cyemezo cyawe cy'uburwayi, uburyo wabanje kuvurwa, n'ibintu by'ubuzima bwawe bwite. Intego ni ukubona imiti ikora neza ifite ingaruka nke zishobora guteza ikibazo.

Ni gute Olanzapine-na-Samidorphan bikora?

Iyi mvange ikora hakoreshejwe uburyo bubiri butandukanye mu bwonko bwawe no mu mubiri wawe. Olanzapine ifunga ibice by'ubwonko bikoresha imisemburo, cyane cyane ibice bya dopamine na serotonin, ibi bikaba bifasha guhosha imikorere mibi y'imiti ijyanye n'indwara zo mu mutwe.

Mugihe, samidorphan ifunga ibice bya opioid olanzapine ishobora gukoresha, ibi bikaba bisanzwe bituma ubushake bwo kurya bwiyongera no kongera ibiro. Tekereza samidorphan nk'ingabo irinda ibintu bimwe bitifuzwa bya olanzapine mugihe yemerera inyungu zayo z'ubuvuzi gukomeza.

Uyu muti ufatwa nk'ukomeye cyane mu cyiciro cy'imiti igabanya ibibazo byo mu mutwe. Irashobora gukoreshwa neza mu guhangana n'ibimenyetso bikomeye by'ubuzima bwo mu mutwe mugihe itanga uburyo bwiza bwo kugenzura ibiro kurusha olanzapine yonyine, nubwo bigisaba gukurikiranwa neza no gusuzumwa buri gihe n'umuvuzi wawe.

Nkwiriye gufata gute Olanzapine-na-Samidorphan?

Fata uyu muti nk'uko byategetswe na muganga wawe, akenshi rimwe ku munsi hamwe n'ibiryo cyangwa utabifite. Urashobora kuwufata n'amazi, amata, cyangwa umutobe - icyo cyose wumva cyiza kuri wowe.

Nta bisabwa byihariye byo kurya mbere cyangwa nyuma yo gufata umuti, nubwo kuwufata hamwe n'ibiryo bishobora gufasha kugabanya ibibazo byo munda. Abantu bamwe basanga bifasha kuwufata ku gihe kimwe buri munsi kugirango bagumane urwego rumwe mu mubiri wabo.

Niba uhindura kuva kuri olanzapine isanzwe ukaza kuri ubu buvuzi buvanga, muganga wawe azakuyobora mu guhindura neza. Ntukigere uhagarika gufata uyu muti ako kanya, kuko ibyo bishobora gutera ibimenyetso byo kuva mu buvuzi cyangwa gusubira inyuma kw'ibimenyetso byawe byo mu mutwe.

Umunyire urupapuro rwose utarukubita, uruhekenya, cyangwa urumenagura. Uyu muti ukorwa kugira ngo usohoke neza iyo ufashwe uko uri, bityo guhindura urupapuro rushobora kugira ingaruka ku buryo ukora neza.

Nzamara Igihe Kingana Iki Ndafata Olanzapine-na-Samidorphan?

Igihe cyo kuvurwa gitandukana cyane ku muntu ku muntu kandi biterwa n'uburwayi bwawe bwihariye n'uburyo wakiriye umuti. Abantu benshi bafite schizophrenia cyangwa bipolar disorder bakeneye kuvurwa igihe kirekire kugira ngo bagumane ubuzima bwiza no kwirinda gusubira inyuma kw'ibimenyetso.

Muganga wawe azagenzura buri gihe uburyo umuti ukora neza kuri wowe niba urimo guhura n'ingaruka zose ziteye impungenge. Ibi biganiro bifasha kumenya niba ukwiye gukomeza, guhindura urugero, cyangwa gutekereza ku zindi nzira zo kuvurwa.

Ku bantu bamwe, kuvurwa birashobora gukomeza mu mezi cyangwa imyaka, mu gihe abandi bashobora gukenera guhindurwa vuba. Ikintu cy'ingenzi ni ukugumana imikoranire myiza n'umuganga wawe ku bijyanye n'uko wumva umeze mu mutwe no mu mubiri.

Ntuzigere ufata icyemezo cyo guhagarika uyu muti wenyine, n'iyo wumva umeze neza. Guhagarika ako kanya bishobora gutera ibimenyetso bikomeye byo kuva mu buvuzi no gusubira inyuma kw'ibimenyetso byo mu mutwe bishobora kuba bigoye kuvura.

Ni Iyihe Ngaruka Ziterwa na Olanzapine-na-Samidorphan?

Kimwe n'indi miti yose, olanzapine-na-samidorphan ishobora gutera ingaruka, nubwo atari buri wese uzihura. Kumva icyo witegura bishobora kugufasha kumva witeguye kandi ukamenya igihe wakwiyambaza muganga wawe.

Ingaruka zikunze kugaragara ushobora guhura nazo zirimo gusinzira, kuribwa umutwe, no kumva umunwa wumye. Ibi akenshi biragenda bikemuka uko umubiri wawe umenyera umuti, akenshi mu byumweru bike bya mbere byo kuvurwa.

Ingaruka zisanzwe

Dore ingaruka zigaragara kenshi, zikaba zifata abantu benshi bafata uyu muti:

• Gusinzira cyangwa guhagarara, cyane cyane mu ntangiriro
• Kuribwa umutwe cyangwa kumva ureremba, cyane cyane iyo uhagurutse
• Umunwa wumye ushobora kuzagenda ukemuka uko igihe kigenda
• Kugorana kwituma bishobora gukemurwa no guhindura imirire
• Kugira irari ryinshi ryo kurya, nubwo akenshi biba bike ugereranyije na olanzapine yonyine
• Kumva unaniwe cyangwa urushye kurusha uko byari bisanzwe
• Kuribwa umutwe akenshi bikemuka uko umubiri wawe umenyera

Izi ngaruka muri rusange ziragendeka kandi akenshi zigenda zigabanuka uko umubiri wawe umenyera umuti. Umuganga wawe ashobora gutanga ingamba zo gufasha kugabanya ingaruka zabyo ku buzima bwawe bwa buri munsi.

Ingaruka zitagaragara cyane ariko zikomeye

Nubwo zitagaragara kenshi, hariho ingaruka zimwe na zimwe zisaba ubufasha bwihuse bw'abaganga kuko zishobora kuba zikomeye:

• Kongera ibiro cyane nubwo hariho ingaruka zirinda za samidorphan
• Urusobe rwinshi rw'isukari mu maraso cyangwa ibimenyetso bya diyabete
• Kugenda kw'imitsi bidasanzwe cyangwa gukakara
• Urugero rukomeye rw'uburwayi bw'uruhu, kubyimba, cyangwa guhumeka bigoye
• Guhinduka kw'umuvuduko w'umutima cyangwa kuribwa mu gituza
• Kuribwa umutwe cyane cyangwa kugwa igihumure
• Ibimenyetso by'ubwandu nk'umuriro cyangwa kubabara mu muhogo bihoraho

Niba ubonye kimwe muri ibi bimenyetso, vugana n'umuganga wawe ako kanya. Kumenya no kuvura vuba ingaruka zikomeye bishobora gukumira ibibazo no kurengera umutekano wawe.

Ingaruka zitagaragara ariko zikomeye

Izi ngaruka ntizisanzwe ariko zisaba ubufasha bwihuse bw'abaganga nibiramuka bibaye:

• Indwara ya neuroleptic malignant syndrome (umuriro mwinshi, imitsi yikakanye, urujijo)
• Tardive dyskinesia (imitsi itunguka itunguka, cyane cyane mu maso)
• Igabanuka rikomeye ry'umubare w'uturemangingo tw'amaraso twera
• Udukorwa, cyane cyane ku bantu badafite amateka y'indwara z'udukorwa
• Ibibazo bikomeye by'umwijima hamwe no guhinduka uruhu cyangwa amaso umuhondo
• Amaraso yiziritse cyangwa ibibazo by'imitsi itwara amaraso

Nubwo izi ngaruka zikomeye zitaba kenshi, kuzimenya bifasha kuguma maso no gushaka ubufasha vuba na bwangu niba bibaye ngombwa. Muganga wawe azajya akugenzura buri gihe kugira ngo amenye ibibazo bishobora kuvuka hakiri kare.

Ninde utagomba gufata Olanzapine-na-Samidorphan?

Uyu muti ntukwiriye buri wese, kandi ibibazo by'ubuzima runaka cyangwa ibihe bishobora kubigira ibyago. Muganga wawe azasuzuma neza amateka yawe y'ubuzima mbere yo kugusaba uyu muti.

Abantu bafite indwara ikomeye y'umwijima ntibagomba gufata uyu muti kuko ibice byombi bikorwa n'umwijima. Mu buryo nk'ubwo, niba ufite allergie izwi kuri olanzapine, samidorphan, cyangwa ibindi bice bitagira akamaro biri muri iyi tablet, ugomba kwirinda uyu muti.

Niba uri gufata imiti ya opioid yo gucunga ububabare, uyu muti ntushobora kuba ukwiriye kuko samidorphan ishobora kubuza imiti ya opioid gukora. Muganga wawe azakenera gusuzuma neza uburyo bwo kuvura butandukanye muri iki gihe.

Abagore batwite cyangwa bonka bagomba kwitabwaho by'umwihariko, kuko umutekano w'uyu muti mu gihe cyo gutwita no konsa utarashyirwaho neza. Umuganga wawe azagereranya inyungu n'ibishobora kuba byatera niba uteganya gutwita cyangwa umaze gutwita.

Izina ry'ubwoko bwa Olanzapine-na-Samidorphan

Izina ry'ubwoko bw'uyu muti uvanga ni Lybalvi, ukorwa na Alkermes. Ubu ni wo muti wenyine uboneka ku isoko uvanga olanzapine na samidorphan muri Leta Zunze Ubumwe z'Amerika.

Lybalvi iza mu mbaraga zitandukanye z'ibinini kugira ngo byorohereze gutanga imiti hakurikijwe ibyo ukeneye n'uburyo wakiriye imiti. Muganga wawe azagena imbaraga zikwiriye kandi ashobora kuzihindura uko igihe kigenda.

Igihe uvugana n'umuganga wawe cyangwa umufarumasiti kuri uyu muti, ushobora kuwuvuga ukoresheje izina rusange (olanzapine-na-samidorphan) cyangwa izina ry'ubucuruzi (Lybalvi). Aya mazina yombi yerekeza ku muti umwe.

Izindi miti isimbura Olanzapine-na-Samidorphan

Hariho indi miti itandukanye ishobora kuvura indwara ya schizophrénie na bipolar disorder niba iyi miti idakwiriye kuri wowe. Izindi miti ya antipsychotique idasanzwe irimo risperidone, quetiapine, aripiprazole, na ziprasidone, buri imwe ifite ibyiza byayo n'ingaruka zayo.

Ku bantu bafite impungenge zidasanzwe zo kongera ibiro, aripiprazole cyangwa ziprasidone bishobora kuba ibisubizo byiza, kuko akenshi bitera kongera ibiro gusa ugereranyije n'imiti ishingiye kuri olanzapine. Lurasidone ni ubundi buryo butera impinduka nto ku biro.

Muganga wawe ashobora kandi gutekereza ku miti igabanya imyumvire nka lithium cyangwa valproate kuri bipolar disorder, cyangwa uburyo bwo guhuza imiti myinshi kugira ngo bigerweho kugenzura ibimenyetso neza n'ingaruka nke.

Uburyo bwo guhitamo indi miti buterwa n'ibimenyetso byawe byihariye, amateka yawe y'ubuzima, indi miti urimo gufata, n'ibyo ukunda ku ngaruka z'imiti n'igihe cyo gufata imiti.

Ese Olanzapine-na-Samidorphan iruta Olanzapine yonyine?

Ku bantu benshi, olanzapine-na-samidorphan itanga ibyiza ugereranyije na olanzapine yonyine, cyane cyane mu bijyanye no kugenzura ibiro. Ubushakashatsi bwa kliniki bwerekana ko iyi miti ihuriyeho akenshi itera kongera ibiro gusa ugereranyije na olanzapine yonyine.

Inyungu zo mu bijyanye n'ubuzima bwo mu mutwe zirasa cyane hagati y'izo mpuzankano zombi, kuko olanzapine ari umuti ukora uvura ibimenyetso by'ubuzima bwawe bwo mu mutwe. Kongeraho samidorphan byihariye bigamije ikibazo cyo kongera ibiro bitabangamiye imikorere ya schizophrenia cyangwa bipolar disorder.

Ariko, "byiza" biterwa n'uko ubuzima bwawe bwifashe. Niba umaze igihe gito ukoresha olanzapine wenyine nta kongera ibiro bikabije, guhindura ntibishobora kuba ngombwa. Muganga wawe azagufasha gupima inyungu n'ibibazo bya buri mpuzankano.

Ubu bufatanye butwara amafaranga menshi kurusha olanzapine yonyine, ibyo bishobora kuzitirwa bitewe n'ubwishingizi bwawe n'imibereho yawe y'ubukungu.

Ibikunze Kubazwa Ku Bya Olanzapine-na-Samidorphan

Ese olanzapine-na-samidorphan ni umutekano ku barwayi ba diyabete?

Uyu muti usaba gukurikiranwa neza niba urwaye diyabete, kuko olanzapine ishobora kugira ingaruka ku isukari yo mu maraso. N'ubwo samidorphan ishobora gufasha kugabanya ingaruka zimwe na zimwe z'imikorere y'umubiri, abantu barwaye diyabete baracyakeneye gukurikiranwa isukari yo mu maraso igihe bafata ubu bufatanye.

Muganga wawe ashobora gukora igeragezwa ry'isukari yo mu maraso kenshi iyo utangiye uyu muti kandi ashobora gukenera guhindura imiti yawe ya diyabete. Ubu bufatanye ntibugira umutekano ku bantu barwaye diyabete, ariko bisaba gukurikiranwa neza na muganga.

Nigomba gukora iki niba mfashe olanzapine-na-samidorphan ku buryo butunguranye?

Niba ku buryo butunguranye ufata umuti mwinshi kurusha urugero rwanditswe, vugana na muganga wawe cyangwa umuntu ushinzwe ubumara ako kanya. Ibimenyetso byo kurenza urugero bishobora kuba ukunebwa gukabije, urujijo, kuvuga nabi, cyangwa guhumeka nabi.

Ntugerageze kwivugisha cyangwa gufata indi miti kugira ngo urwanye kurenza urugero. Shakisha ubufasha bw'ubuvuzi bw'umwuga ako kanya, kandi uzane icupa ry'umuti niba ujya mu cyumba cy'abarwayi b'igitaraganya.

Nigomba gukora iki niba nirengagije urugero rwa olanzapine-na-samidorphan?

Niba wibagiwe gufata urugero, rufate uko wibuka, keretse igihe cyo gufata urugero rukurikira kigeze. Mu gihe nk'icyo, reka urugero wibagiwe ukomeze gahunda yawe isanzwe - ntufate urugero ebyiri icyarimwe.

Kutagera ku rugero rimwe na rimwe ntibizatuma ugira ibibazo ako kanya, ariko gerageza kugira gahunda ihamye kugira ngo ugire ingaruka nziza zo kuvurwa. Tekereza gushyiraho umwanya wo kwibutswa buri munsi kuri terefone yawe cyangwa ukoreshe agasanduku k'imiti kugira ngo bigufashe kwibuka.

Nshobora guhagarika ryari gufata olanzapine-na-samidorphan?

Ntuzigere uhagarika gufata uyu muti ako kanya utabanje kugisha inama umuganga wawe. Guhagarika ako kanya bishobora gutera ibimenyetso byo kuva mu miti no kugaruka kw'ibimenyetso byo mu mutwe bishobora kuba bikomeye kurusha mbere yo kuvurwa.

Umuganga wawe azagufasha gukora gahunda yo kugabanya buhoro buhoro niba guhagarika bikwiye. Iyi gahunda mubisanzwe ifata ibyumweru byinshi cyangwa amezi, bitewe n'igihe umaze ufata uyu muti n'uburyo umubiri wawe witwara.

Nshobora kunywa inzoga niba mfata olanzapine-na-samidorphan?

Ni byiza kwirinda inzoga niba ufata uyu muti, kuko ibintu byombi bishobora gutera gusinzira no kuribwa umutwe. Kubivanga byongera ibyago byo kugwa, impanuka, no gutakaza ubwenge.

Niba uhisemo kunywa rimwe na rimwe, bikore mu rugero ruto cyane kandi umenye ko ingaruka zongereka. Buri gihe ganira ku kunywa inzoga n'umuganga wawe, kuko ashobora kugusaba kuzireka burundu bitewe n'ubuzima bwawe bwite.