Pafolacianine ni iki: Ibikoreshwa, Urutonde rw'imiti, Ingaruka ziterwa n'ibindi

Pafolacianine ni umuti ukoreshwa mu gushushanya ifoto yerekana ibintu bifite urumuri, ifasha abaganga kubona neza uturemangingo twa kanseri mu gihe cyo kubaga. Uyu muti wihariye ukora nk'ikaramu yandika ibintu bigaragara ku turemangingo twa kanseri, bituma bitanga urumuri iyo bikoreshejweho urumuri rwihariye rwa infrared kugira ngo abaganga babashe kumenya no gukuraho ibibyimba neza mu gihe barinda uturemangingo twiza.

Uyu muti ugaragaza iterambere rikomeye mu kubaga neza, cyane cyane mu bijyanye no kubaga kanseri y'intanga ngore. Itangwa binyuze mu muyoboro w'amaraso mbere yo kubaga kandi yegerana mu turemangingo twa kanseri, ifasha abaganga gukora imirimo igoye yo kubaga bafite icyizere kinini n'ubunyamwuga.

Pafolacianine ikoreshwa mu iki?

Pafolacianine ikoreshwa cyane cyane mu gufasha abaganga kumenya uturemangingo twa kanseri y'intanga ngore mu gihe cyo kubaga. Uyu muti ukora nk'ubuyobozi bugaragara, ugaragaza uturemangingo twa kanseri bishobora kuba bigoye gutandukanya n'uturemangingo twiza n'amaso yambaye ubusa.

Uyu muti ukoreshwa mu gushushanya ifoto yemejwe by'umwihariko ku bagore bakuze bari mu cyiciro cyo kubagwa kubera gukeka cyangwa kwemeza kanseri y'intanga ngore. Ifasha abaganga gufata ibyemezo bifitiye inyungu ku bijyanye n'uturemangingo bagomba gukuraho n'abo bagomba kurengera, bishobora guteza imbere ibisubizo byo kubaga.

Uyu muti urimo no kwigwa ku zindi nzego zo kubaga kanseri, nubwo kanseri y'intanga ngore ikomeza kuba ikoreshwa ryemewe. Itsinda ryawe ry'abaganga bazagena niba uyu muti ukoreshwa mu gushushanya ifoto ukwiye ku miterere yawe yihariye.

Pafolacianine ikora ite?

Pafolacianine ikora yibanda ku biremwa bya folate, ari zo poroteyine ziboneka mu bwinshi ku turemangingo twinshi twa kanseri. Tekereza kuri izi receptor nk'ahantu ho guhagarara uturemangingo twa kanseri dukoresha kugira ngo duteranye intungamubiri dukeneye kugira ngo dukure kandi tubaho.

Iyo imaze guterwa mu maraso yawe, umuti ugenda mu mubiri wawe wose ukifatira kuri izo folate receptors. Uturemangingo twa kanseri mubisanzwe tugira izo receptors nyinshi kurusha uturemangingo twiza, bityo umuti ukibumbira cyane mu gice cya kanseri.

Mugihe cyo kubaga, umuganga ubaga akoresha kamera idasanzwe ikoresha imirasire ya infrared kugirango abone aho umuti wibumbiye. Igice cya kanseri kigaragara nkicyaka cyangwa kigafata urumuri iyo gicishijwe muri urwo rumuri rwihariye, bigatuma habaho itandukaniro rirambuye riri hagati y’ahantu heza n’ahantu harwaye kanseri.

Ibi bifatwa nk'umuti ukoreshwa mu isuzuma ryo mu rwego rwo hagati utanga amakuru y'ingirakamaro atahindura cyane imikorere isanzwe y'umubiri wawe. Uwo muti ntuvura kanseri ubwayo ariko ukoreshwa nk'igikoresho cyo kuyobora mu kubaga.

Nkwiriye Gufata Uyu Muti Wa Pafolacianine Nte?

Pafolacianine itangwa gusa n'abakora mu buvuzi binyuze mu muyoboro wa intravenous (IV) mu bitaro cyangwa mu kigo kibagisha. Ntabwo uzajya ufata uyu muti uri mu rugo cyangwa unywa.

Umuti mubisanzwe utangwa amasaha 1 kugeza kuri 9 mbere yuko kubaga gutangira. Itsinda ry'abaganga bazagena igihe nyacyo gishingiye ku buryo bwawe bwihariye bwo kubaga n'ibyo ukeneye mu buvuzi.

Ntabwo bisaba gufata uyu muti hamwe n'ibiryo cyangwa amata kuko utererwa mu maraso yawe. Ariko, itsinda ry'abaganga bakubaga bashobora kuguha amabwiriza yihariye yerekeye kurya cyangwa kunywa mbere yuko ubaga, ukwiriye kuyakurikiza neza.

Uburyo bwo gutegura buroroshye. Umuforomo wawe azatangiza umurongo wa IV hanyuma akinjiza umuti buhoro buhoro mu minota mike. Hanyuma uzategereza igihe gikwiye mbere yuko kubaga gutangira.

Nkwiriye Gufata Pafolacianine Igihe Kingana Gite?

Pafolacianine itangwa nk'urugero rumwe mbere yo kubaga, ntabwo ari nk'ubuvuzi bukomeza. Uzahabwa umuti rimwe, kandi uzakora mu gihe cyo kubaga kwawe.

Umuti uguma mu mubiri wawe amasaha menshi, bikaba bihagije ku bikorwa byinshi byo kubaga. Umubiri wawe uzikuramo uyu muti mu minsi ikurikira nta kindi kivuzi gisabwa.

Bitandukanye n'imiti myinshi isaba doze ya buri munsi cyangwa imiti ikoreshwa igihe kirekire, pafolacianine yagenewe gukoreshwa rimwe gusa. Nta mpungenge zo kwibuka gufata doze cyangwa gucunga gahunda igoye yo gufata imiti.

Ni Ibihe Bikorwa Bigaragara Biterwa na Pafolacianine?

Abantu benshi bakira neza pafolacianine, ibikorwa bigaragara bikaba akenshi byoroheje kandi by'igihe gito. Ibikorwa bisanzwe bibaho nyuma gato yo guhabwa urushinge kandi bikunda gukira vuba.

Dore ibikorwa bishobora kukubaho, wibuke ko abantu benshi batagira ibikorwa bigaragara na gato:

Ibikorwa bisanzwe birimo:

• Urugimbu cyangwa kubabara mu nda
• Guhinduka kw'amazi y'inkari by'igihe gito (bishobora kugaragara nk'umuhondo cyangwa icyatsi)
• Ibikorwa byoroheje ku ruhu ahaterwa urushinge
• Kuribwa umutwe cyangwa kumva uruhutse
• Guhinduka kw'uburyo ibintu biryoha by'igihe gito

Ibikorwa bitabaho kenshi ariko bikomeye bishobora kuba birimo:

• Urukerereza ruterwa n'imiti rufite ibimenyetso nk'umururumba, kwishima, cyangwa guhumeka bigoranye
• Guhinduka gukomeye mu gitutu cy'amaraso
• Urugimbu rukabije cyangwa kuruka
• Kubabara mu gituza cyangwa guhinduka kw'umuvuduko w'umutima
• Ibikorwa bikabije ahaterwa urushinge

Itsinda ryawe ry'abaganga rizakurikirana neza nyuma yo guhabwa umuti no mu gihe cyo kubagwa. Niba ubonye ibimenyetso bibangamiye, bateguye neza kubikemura ako kanya.

Ninde Utagomba Gufata Pafolacianine?

Pafolacianine ntibereye buri wese, kandi itsinda ryawe ry'abaganga rizasuzuma neza amateka yawe y'ubuzima mbere yo gufata icyemezo niba ikwiriye kuri wowe. Uyu muti ufite ibituma utakoreshwa ku bantu bamwe.

Ntabwo ugomba guhabwa pafolacianine niba ufite allergie izwi kuri uyu muti cyangwa kuri kimwe mu bigize uyu muti. Muganga wawe azaganira ku ngaruka zose wigeze kugira ziterwa n’imiti cyangwa ibikoresho byifashishwa mu gupima.

Abantu bafite indwara zikomeye z’impyiko ntibashobora kuba bakwiriye guhabwa uyu muti, kuko umubiri wifashisha imikorere y’impyiko kugira ngo ukuremo uyu muti. Muganga wawe azareba ibizamini by’imikorere y’impyiko zawe mbere yo gufata iki cyemezo.

Niba utwite cyangwa wonsha, umutekano wa pafolacianine nturashyirwaho neza. Itsinda ryawe ry’abaganga rizagereranya neza inyungu n’ibibazo muri ibi bihe.

Indwara zimwe na zimwe z’umutima cyangwa ibibazo by’umuvuduko w’amaraso bishobora gutuma uyu muti utakwiriye. Muganga ubaga n’uwugufasha mu kubagwa bazareba amateka yawe yose y’ubuvuzi kugira ngo barebe umutekano wawe.

Amazina y’ubucuruzi ya Pafolacianine

Pafolacianine icururizwa ku izina rya Cytalux muri Leta Zunze Ubumwe z’Amerika. Iri ni ryo zina rikoreshwa cyane mu bucuruzi ushobora guhura na ryo iyo uganira kuri uyu muti n’ikipe yawe y’ubuzima.

Uyu muti ushobora kwitwa izina rusange (pafolacianine) cyangwa izina ry’ubucuruzi (Cytalux) mu buryo bukurikirana mu rwego rw’ubuvuzi. Amazina yombi yerekeza ku muti umwe ufite imitungo imwe n’ingaruka zimwe.

Igihe utegura kubagwa cyangwa ureba gahunda yawe y’ubuvuzi, ushobora kubona izina rimwe muri ayo akoreshwa mu bitabo byawe by’ubuvuzi cyangwa mu mabwiriza yo gusohoka. Ntukagire impungenge niba ubonye amazina yombi - ni umuti umwe.

Uburyo bwo gusimbuza Pafolacianine

Ubu, hari uburyo butaziguye bwo gusimbuza pafolacianine mu kubaga hifashishijwe urumuri mu ndwara ya kanseri y’intanga. Uburyo bwa kera bwo kubaga bushingiye ku isuzuma ry’amaso y’abaganga n’uburambe nta buyobozi bw’urumuri.

Izindi tekiniki zikoreshwa mu isuzuma mu gihe cyo kubaga zirimo ultrasound ikoreshwa mu gihe cyo kubaga, ikoresha imiraba y'amajwi kugira ngo ikore amashusho y'ibice by'imbere mu gihe nyacyo. Ariko, ibi bitanga amakuru atandukanye n'isuzuma rikoresha urumuri.

Ibice bimwe by'ubuvuzi bikoresha ibindi bintu bikoresha urumuri mu bwoko butandukanye bwo kubaga kanseri, ariko ibi ntibisanzwe gukoreshwa mu buryo busimburana na pafolacianine mu kubaga kanseri y'intanga.

Umuvuzi wawe uzaganira ku buryo bwiza bujyanye n'ikibazo cyawe, gishobora kuba kirimo gukoresha pafolacianine, uburyo bwa kera bwo kubaga, cyangwa guhuza uburyo bwo kugera ku musaruro mwiza.

Ese Pafolacianine iruta izindi nzira zo gushushanya?

Pafolacianine itanga inyungu zidasanzwe ugereranyije n'inzira gakondo zo gushushanya mu kubaga, cyane cyane mu bushobozi bwayo bwo kugaragaza ibice bya kanseri mu gihe nyacyo cyo kubaga. Ibi bishobora kuba ingirakamaro cyane mu manza zigoranye aho ibice bya kanseri bishobora kugorana gutandukanya n'ibice by'ubuzima.

Uburyo gakondo bwo kubaga bushingiye cyane cyane ku isuzuma ry'amaso ry'abaganga, isuzuma rikoreshwa ku gice cy'umubiri, n'uburambe. Nubwo ubu buryo bufite akamaro, ntibitanga andi makuru agaragara atangwa n'isuzuma rikoresha urumuri.

Ugereranyije n'izindi tekiniki zo gushushanya nka CT scans cyangwa MRI, pafolacianine itanga amakuru mu gihe cyo kubaga nyako aho kubikora mbere yaho. Ubu buyobozi mu gihe nyacyo bushobora gufasha abaganga gufata ibyemezo bifitiye akamaro ku gukuraho ibice by'umubiri.

Guhitamo hagati ya pafolacianine n'izindi nzira biterwa n'ikibazo cyawe, uko kubaga kwawe kugoye, n'ubuhanga bw'abaganga bawe. Abaganga benshi bakoresha uburyo bwinshi hamwe kugira ngo bagere ku musaruro mwiza.

Ibikunze Kubazwa Kuri Pafolacianine

Ese Pafolacianine ifite umutekano ku bantu barwaye indwara z'impyiko?

Pafolacianine ntishobora gukwira abantu barwaye indwara zikomeye z'impyiko kuko impyiko zigira uruhare runini mu gukuraho imiti mu mubiri wawe. Muganga wawe azasuzuma ibizamini by'imikorere y'impyiko mbere yo gufata icyemezo niba uyu muti ukwiriye kuri wowe.

Niba ufite ibibazo byoroheje cyangwa byo hagati by'impyiko, itsinda ryawe ry'abaganga rishobora gukomeza gutekereza gukoresha pafolacianine ariko rizakurikirana hafi. Bashobora kandi guhindura ibindi bice by'ubuvuzi bwawe kugira ngo bishyire mu gaciro gukurwaho kw'imiti gahoro.

Nkwiriye gukora iki niba ngize allergie kuri Pafolacianine?

Kubera ko pafolacianine itangwa mu bitaro hamwe n'abantu b'inzobere mu by'ubuvuzi bahari, allergie iyo ari yo yose izahita imenyekana kandi ivurwe n'ikipe yawe y'ubuzima. Ntabwo ukeneye gufata icyo aricyo cyose.

Ibimenyetso bya allergie birimo imitsi, kuribwa, guhumeka bigoranye, cyangwa kubyimba. Itsinda ryawe ry'ubuvuzi ryatojwe gukemura ibi bibazo kandi rifite imiti yihutirwa ihari niba bibaye ngombwa.

Nkwiriye gukora iki niba mfite impungenge ku bijyanye n'umuti?

Bitandukanye n'imiti ufata mu rugo, pafolacianine itangwa n'inzobere mu by'ubuzima bazakukurikirana mu gihe cyose cy'inzira. Niba ufite impungenge mbere yo guhabwa umuti, uziganire n'ikipe yawe ibaga.

Abaganga bawe bahari kugira ngo bakemure ibibazo byose cyangwa impungenge ushobora kugira ku bijyanye n'umuti cyangwa kubagwa kwawe. Ntuzuyaze kuvuga niba hari ikintu kitumvikana neza.

Ni ryari umuti uzava mu mubiri wanjye?

Pafolacianine isanzwe ikurwaho mu mubiri wawe mu minsi mike nyuma yo kubagwa. Impyiko zawe zizasanzwe zikura umuti, kandi uzawukuraho unyuza mu nkari zawe.

Ushobora kubona ibara ry'inkari zawe ryahindutse by'agateganyo umunsi umwe cyangwa ibiri nyuma yo guhabwa umuti. Ibi ni ibisanzwe kandi birerekana ko umubiri wawe uri gutunganya no gukuraho umuti nk'uko byitezwe.

Nshobora gutwara imodoka nyuma yo guhabwa Pafolacianine?

Kubera ko pafolacianine itangwa mbere yo kubagwa, ntuzatwara imodoka ako kanya nyuma yo kuyihabwa. Umuti ubwawo ntugira ingaruka ku bushobozi bwawe bwo gutwara imodoka, ariko uzaba uri kubagwa kandi bishoboka ko uhabwa anesthesia.

Itsinda ry'abaganga bakubaga bazatanga amabwiriza arambuye yerekeye igihe ushobora kongera gutwara imodoka bitewe n'uburyo wakoreweho n'uburyo urimo gukira. Iyi myanzuro izaterwa cyane n'uburyo wakoreweho n'anesthesia kurusha uko byaterwa na pafolacianine ubwayo.