Ni iki Phenelzine: Ibikoresho, Urutonde rw'imiti, Ingaruka zayo n'ibindi

Phenelzine ni umuti wandikirwa na muganga uvura umubabaro wo mu mutwe, ukaba mu cyiciro cy'imiti yitwa monoamine oxidase inhibitors (MAOIs). Akenshi wandikirwa iyo indi miti ivura umubabaro wo mu mutwe itatanze umuti uhagije w'ibimenyetso by'umubabaro wo mu mutwe. Nubwo atari wo muti wa mbere abaganga bakoresha, phenelzine ishobora kugira akamaro gakomeye ku bantu bamwe na bamwe, cyane cyane abafite umubabaro wo mu mutwe udasanzwe cyangwa umubabaro wo mu mutwe utavurwa.

Phenelzine ni iki?

Phenelzine ni umuti ukomeye uvura umubabaro wo mu mutwe ukora mu buryo butandukanye n'imiti myinshi ya none ivura umubabaro wo mu mutwe. Ni icyo abaganga bita monoamine oxidase inhibitor, bivuze ko ifunga za enzyme zimwe na zimwe mu bwonko bwawe zishenya imisemburo igenga imitekerereze nka serotonin, norepinephrine, na dopamine.

Uyu muti umazeho kuva mu myaka ya za 1960 kandi ukomeje kuba igikoresho cy'ingenzi mu kuvura umubabaro wo mu mutwe, cyane cyane iyo indi miti itagize icyo ikora. Muganga wawe ashobora gutekereza gukoresha phenelzine niba wagerageje indi miti myinshi ivura umubabaro wo mu mutwe ntigire icyo ikora, cyangwa niba ufite ibimenyetso byihariye byitabira neza MAOIs.

Phenelzine isaba gukurikiranwa neza no kugabanya ibyo urya, ariko ku bantu benshi, ishobora gutanga umuti ugaragara w'ibimenyetso by'umubabaro wo mu mutwe iyo indi miti itashoboye gukora.

Phenelzine ikoreshwa mu kuvura iki?

Phenelzine ikoreshwa cyane cyane mu kuvura indwara ikomeye y'umubabaro wo mu mutwe, cyane cyane iyo indi miti ivura umubabaro wo mu mutwe itagize icyo ikora. Ifasha cyane cyane abantu bafite umubabaro wo mu mutwe udasanzwe, urimo ibimenyetso nko kongera ubushake bwo kurya, gusinzira cyane, no kwanga cyane.

Abaganga bashobora kandi kwandikira phenelzine indwara zimwe na zimwe z'ubwoba, zirimo indwara y'ubwoba bwo mu mibanire n'abandi n'indwara y'ubwoba bwo guhagarika umutima. Abantu bamwe bafite bulimia nervosa cyangwa izindi ndwara zo kurya nabo bashobora kungukira kuri uyu muti.

Umuvuzi wawe ashobora kugusaba gufata phenelzine niba wumva ibimenyetso byo kwiheba nk'agahinda gakomeye, kutagira inyungu mu bikorwa, umunaniro, cyangwa kugorana kwibanda. Bifasha cyane iyo ibyo bimenyetso birimo icyo abaganga bita "ibintu bidasanzwe" nk'ubushobozi bwo guhinduka kw'amarangamutima, aho amarangamutima yawe ashobora guhinduka by'igihe gito bitewe n'ibintu byiza.

Phenelzine ikora ite?

Phenelzine ikora ibuza enzymes bita monoamine oxidases mu bwonko bwawe. Izi enzymes zisanzwe zisenya imiti ikomeye ifasha mu marangamutima nka serotonin, norepinephrine, na dopamine. Iyo phenelzine ibuza izi enzymes, imiti myinshi ifasha kumva neza iguma mu bwonko bwawe.

Bitekereze nk'ugufunga umwobo wo kuvomera muri bati. Aho imiti ifasha mu marangamutima y'ubwonko bwawe ishirira vuba, iguma igihe kirekire kugira ngo ifashe kunoza amarangamutima yawe no kugabanya ibimenyetso byo kwiheba. Iyi nzira ifata igihe, niyo mpamvu ushobora kutumva inyungu zose mu byumweru byinshi.

Uyu muti ufashwe nk'ukomeye kandi ufite akamaro, ariko bisaba kwitabwaho cyane kurusha imiti mishya yo kurwanya kwiheba. Inkuru nziza ni uko ku bantu basubiza neza kuri phenelzine, ishobora gutanga ubufasha bukomeye ku bimenyetso byo kwiheba iyo indi miti itashoboye gufasha.

Nkwiriye gufata phenelzine nte?

Fata phenelzine nk'uko umuganga wawe abitegeka, akenshi inshuro 2-3 ku munsi hamwe cyangwa hatariho ibiryo. Urashobora kuyifata hamwe n'amata cyangwa amazi, kandi ntacyo bitwaye niba urya mbere cyangwa nyuma yo kuyifata. Ariko, gutegura igihe cyo gufata imiti yawe buri munsi bifasha kugumisha urwego ruzigama mu mubiri wawe.

Tangira n'urugero ruto ruzana akamaro umuganga wawe agusaba, akenshi hafi ya 15mg ifatwa inshuro 2-3 ku munsi. Umuganga wawe ashobora kuzamura buhoro buhoro urugero rwawe bitewe n'uko usubiza kandi wihanganira umuti. Abantu benshi bafata hagati ya 45-90mg ku munsi, igabanyijemo ibice byinshi.

Ikintu cy'ingenzi cyane cyerekeye gufata phenelzine ni ukurikiza ibyo kurya bigenewe. Uzaba ukeneye kwirinda ibiryo birimo tyramine nyinshi, harimo foromaje zishaje, inyama zitunganyirijwe, ibiryo byabitswe, n'ibinyobwa bisindisha bimwe na bimwe. Muganga wawe cyangwa umufarumasiti azaguha urutonde rwuzuye rw'ibiryo byo kwirinda.

Ntuzigere uhagarika gufata phenelzine mu buryo butunguranye, kuko ibyo bishobora gutera ibimenyetso bidasanzwe byo kuva mu mutwe. Niba ukeneye guhagarika, muganga wawe azagufasha kugabanya buhoro buhoro mu byumweru byinshi.

Nzamara Mfata Phenelzine Igihe Kingana Gite?

Abantu benshi bakeneye gufata phenelzine byibuze amezi 6-12 kugira ngo bagumane iterambere ryabo mu bimenyetso byo kwiheba. Muganga wawe azasaba gukomeza imiti mu mezi menshi nyuma yo gutangira kumva umeze neza kugira ngo wirinde ko kwiheba bigaruka.

Abantu bamwe bashobora gukenera gufata phenelzine imyaka myinshi, cyane cyane niba bafite kwiheba kugaruka cyangwa niba izindi miti igabanya kwiheba itarabakundiye. Ibi ni ibisanzwe rwose kandi bifite umutekano iyo bikurikiranwa neza n'umuganga wawe.

Umwanzuro wo gukomeza gufata phenelzine igihe kingana gute biterwa n'ibintu byinshi, harimo uko wemera imiti, niba ubona ingaruka ziterwa nayo, n'amateka yawe yo kwiheba. Muganga wawe azakorana nawe kugira ngo amenye igihe cyiza cyo kuvura cyerekeye uko wimeze.

Ni Iyihe Ngaruka Ziterwa na Phenelzine?

Kimwe n'indi miti yose, phenelzine ishobora gutera ingaruka ziterwa nayo, nubwo atari buri wese uzibona. Kumva icyo witegura bishobora kugufasha kumva witeguye kandi umenye igihe cyo kuvugana na muganga wawe.

Ingaruka zisanzwe abantu benshi bahura nazo zirimo:

• Kuribwa umutwe cyangwa kumva uruhuka, cyane cyane iyo uhagurutse
• Gusinzira cyane cyangwa kumva unaniwe ku manywa
• Umunwa wumye
• Kugorana kwituma
• Kongera ibiro
• Ingaruka ku mibonano mpuzabitsina nk'ugushaka gukora imibonano mpuzabitsina kugabanuka cyangwa kugorana kugera ku byishimo
• Ibibazo byo gusinzira cyangwa kutagira ibitotsi
• Urugimbu cyangwa kuribwa mu nda

Izi ngaruka zisanzwe zikunze gukira uko umubiri wawe umenyera umuti mu byumweru bya mbere. Abantu benshi basanga kuguma banywa amazi menshi, kurya ibiryo birimo fibre nyinshi, no gukora imyitozo ngororamubiri buri gihe bishobora gufasha mu guhangana n'izi ngaruka.

Ingaruka zitavugwa cyane ariko zikomeye zisaba ubufasha bwihuse bw'abaganga. Izi ngaruka zitavugwa cyane ariko z'ingenzi zirimo:

• Kuribwa umutwe cyane hamwe no gukakara mu ijosi
• Kuribwa mu gituza cyangwa umutima utera cyane
• Urugimbu rukabije no kuruka
• Umubyigano w'umuvuduko w'amaraso mwinshi
• Urujijo cyangwa guhagarara umutima
• Umuhondo w'uruhu cyangwa amaso
• Inkari z'umukara cyangwa imyanda y'amazi

Niba ubonye izi ngaruka zikomeye, vugana n'umuganga wawe ako kanya cyangwa ushake ubufasha bwihutirwa bw'ubuvuzi. Izi ngaruka ntizikunze kubaho ariko zishobora kugaragaza ibibazo bikomeye bisaba kuvurwa vuba.

Ninde utagomba gufata Phenelzine?

Phenelzine ntirinzwe kuri buri wese, kandi muganga wawe azasuzuma neza amateka yawe y'ubuzima mbere yo kuyandika. Indwara zimwe na zimwe n'imiti bishobora guhura mu buryo buteye akaga na phenelzine.

Ntabwo ugomba gufata phenelzine niba ufite:

• Indwara ikomeye y'umwijima cyangwa ibibazo by'umwijima
• Indwara ikomeye y'impyiko
• Indwara y'umutima cyangwa umuvuduko w'amaraso mwinshi utagenzurwa
• Amateka y'urwara rwo mu bwonko cyangwa kuva amaraso mu bwonko
• Pheochromocytoma (igishyitsi gike cyane cyo mu ngingo ya adrenal)
• Ubu ufata indi miti igabanya ubwoba, cyane cyane SSRIs cyangwa SNRIs

Ikindi kandi, phenelzine bisaba kwitonda cyane niba utwite, uteganya gutwita, cyangwa wonka. Muganga wawe azagereranya neza inyungu n'ibibazo muri ibyo bihe.

Imyaka nayo ishobora kuba impamvu, kuko abantu bakuze bashobora kwumva cyane ingaruka za phenelzine, cyane cyane isereri no guhinduka kw'umuvuduko w'amaraso. Muganga wawe ashobora gutangira n'urugero ruto akagukurikiranira hafi niba urengeje imyaka 65.

Amazina y'ubwoko bwa Phenelzine

Izina ry'ubwoko bwa phenelzine ni Nardil, akaba ari ryo rimenyerewe cyane mu kuvura iyi miti. Ushobora kandi kubona yitwa izina ryayo rusange, phenelzine sulfate, ku icupa ryawe ryandikiwe.

Uramutse wakira izina ry'ubwoko rya Nardil cyangwa phenelzine rusange, byombi birimo ibikoresho bikora kimwe kandi bikora kimwe. Farumasi yawe ishobora guhinduranya hagati y'ubwoko n'ubwoko rusange bitewe n'uko biboneka n'ubwishingizi bwawe.

Niba ufite impungenge zo guhinduranya hagati y'ubwoko n'ubwoko rusange, ganira na muganga wawe cyangwa umufarumasiti. Bashobora gufasha kumenya neza ko urimo kubona imiti ihwanye kandi bagasubiza ibibazo byose bijyanye n'imikorere cyangwa ingaruka zayo.

Uburyo bwo gusimbuza Phenelzine

Niba phenelzine itagukwiriye, imiti myinshi isimbura ishobora kuvura agahinda neza. Muganga wawe ashobora gutekereza ku zindi MAOIs nka tranylcypromine (Parnate) cyangwa isocarboxazid (Marplan), zikora kimwe ariko zishobora kugira ingaruka zitandukanye.

Muri rusange, abaganga bashobora kugerageza imiti mishya yo kurwanya agahinda nka selective serotonin reuptake inhibitors (SSRIs) nka sertraline (Zoloft) cyangwa escitalopram (Lexapro). Iyi miti akenshi igira imbogamizi nke z'imirire n'imikoranire y'imiti kurusha phenelzine.

Izindi nzira zirimo ibinini byongera serotonin-norepinephrine (SNRIs) nka venlafaxine (Effexor) cyangwa duloxetine (Cymbalta). Ku bantu bamwe, imiti idasanzwe yo kurwanya depression nka bupropion (Wellbutrin) cyangwa mirtazapine (Remeron) bishobora kuba ibisubizo byiza.

Igisubizo cyiza giterwa n'ibimenyetso byawe byihariye, amateka yawe y'ubuvuzi, n'uburyo wakiriye izindi miti. Muganga wawe azakorana nawe kugirango abone igisubizo gikwiriye cyane kubyo ukeneye.

Ese Phenelzine iruta izindi miti irwanya depression?

Phenelzine ntiruta izindi miti irwanya depression, ariko irashobora gukora neza ku bantu bamwe n'ubwoko bwihariye bwa depression. Bifitiye akamaro cyane kubantu bafite depression idakira mugihe izindi miti itakoze.

Kubantu bafite depression idasanzwe, phenelzine akenshi ikora neza kuruta imiti mishya irwanya depression nka SSRIs. Depression idasanzwe irimo ibimenyetso nk'ubushobozi bwo guhindura imyumvire, kongera ubushake bwo kurya, gusinzira cyane, no kumva cyane kwangwa.

Ariko, phenelzine isaba gucunga neza kuruta imiti myinshi ya none irwanya depression. Uzakenera gukurikiza ibiribwa bikarishye kandi umenye imiti ishobora guhura. Abaganga benshi bakunda kugerageza imiti mishya irwanya depression mbere kuko akenshi byoroshye gucunga kandi bifite imbogamizi nkeya.

Umuti mwiza urwanya depression ni uwo ukora kuri wewe ufite ingaruka zifatika. Kubantu bamwe, ni phenelzine, mugihe abandi babona neza imiti mishya. Muganga wawe azagufasha kubona ikwiriye hashingiwe ku bimenyetso byawe, amateka yawe y'ubuvuzi, n'imibereho yawe.

Ibikunze Kubazwa Kuri Phenelzine

Ese Phenelzine irakwiriye kubantu bafite indwara z'umutima?

Phenelzine ishobora kugira ingaruka ku mitsi y'amaraso n'umuvuduko w'umutima, bityo bisaba kwitonderwa cyane niba ufite indwara y'umutima. Muganga wawe azasuzuma uko umutima wawe umeze kandi ashobora gufata icyemezo cyo gushyira imbere inyungu kurusha ibyago, cyane cyane niba izindi miti ivura depression itarakoze.

Niba ufite indwara yoroheje y'umutima, muganga wawe ashobora no kugutera phenelzine ariko akagukurikiranira hafi. Ashobora gupima umuvuduko w'amaraso yawe buri gihe kandi ashobora gutangira n'urugero ruto. Ariko, niba ufite indwara ikomeye y'umutima, umuvuduko mwinshi w'amaraso utagenzurwa, cyangwa watewe n'umutima vuba aha, phenelzine ntishobora kuba itekanye kuri wowe.

Nkwiriye gukora iki niba nanyweye phenelzine nyinshi ku buryo butunguranye?

Niba unyweye phenelzine nyinshi ku buryo butunguranye, vugana na muganga wawe cyangwa umuntu ushinzwe iby'uburozi ako kanya, kabone niyo utumva ibimenyetso ako kanya. Kunywa doze nyinshi bishobora gutera impinduka zikomeye ku muvuduko w'amaraso, umuvuduko w'umutima, n'ubushyuhe bw'umubiri.

Ibimenyetso byo kunywa phenelzine nyinshi bishobora kuba kubabara umutwe cyane, kubabara mu gituza, umutima utera cyane, urujijo, umujinya, cyangwa kutagira ubwenge. Ntukibagirwe gutegereza ibimenyetso mbere yo gushaka ubufasha, kuko ingaruka zo kunywa doze nyinshi zishobora gutinda ariko zikaba zikomeye.

Bika nimero ya telefone y'umuntu ushinzwe iby'uburozi (1-800-222-1222 muri Amerika) hafi yawe, kandi ntugatinye guhamagara serivisi zihutirwa niba urimo guhura n'ibimenyetso bikomeye cyangwa niba utabasha kuvugana na muganga wawe ako kanya.

Nkwiriye gukora iki niba nirengagije kunywa phenelzine?

Niba wibagiwe kunywa phenelzine, iyinywe ako kanya wibukiye, keretse igihe cyo kunywa doze ikurikira kigeze. Muri icyo gihe, reka doze wibagiwe hanyuma ukomeze gahunda yawe isanzwe. Ntukigere unywa doze ebyiri icyarimwe kugira ngo ushyire mu mwanya doze wibagiwe.

Kutanywa doze rimwe na rimwe ntibiteje akaga, ariko gerageza kunywa imiti yawe buri gihe kugira ngo ubashe kubona ibisubizo byiza. Niba ukunda kwibagirwa kunywa imiti, tekereza gukoresha igikoresho cyo gutegura imiti cyangwa gushyiraho ibyibutso kuri telefone yawe kugira ngo bigufashe gukurikiza gahunda.

Niba usiba imiti kenshi cyangwa ufite impungenge ku bijyanye n'igihe ufata imiti, ganira na muganga wawe cyangwa umufarumasiti. Bashobora kugufasha gushyiraho ingamba zo kwibuka imiti yawe cyangwa guhindura gahunda yawe yo kuyifata niba bikenewe.

Ni ryari nshobora kureka gufata Phenelzine?

Ntuzigere uhagarika gufata phenelzine mu buryo butunguranye, kuko ibi bishobora gutera ibimenyetso bitari byiza byo kuva mu miti nk'izunguzungu, isesemi, kubabara umutwe, no guhinduka kw'amarangamutima. Muganga wawe azagufasha kugabanya buhoro buhoro urugero rwawe mu byumweru byinshi igihe kigeze cyo guhagarika.

Umwanzuro wo guhagarika phenelzine ugomba gufatwa buri gihe hamwe na muganga wawe, kabone niyo wumva umeze neza cyane. Abantu benshi bakeneye gukomeza gufata imiti yabo igabanya ubwoba mu mezi cyangwa imyaka kugirango birinde ko umubabaro usubira.

Niba urimo guhura n'ingaruka zitari nziza cyangwa ushaka kugerageza undi muti, biganireho na muganga wawe. Bashobora kugufasha guhindura neza ku bundi buvuzi mugihe bagabanya ibyago byo kuva mu miti cyangwa gusubira kw'umubabaro.

Nshobora kunywa inzoga nkanwa Phenelzine?

Ugomba kwirinda inzoga mugihe ufata phenelzine, cyane cyane ubwoko bumwe bw'ibinyobwa bisembuye. Byeri, divayi, n'ibindi binyobwa bisembuye bishobora gukorana nabi na phenelzine kandi bigatera izamuka ry'amaraso ryihuse kandi rikomeye.

N'ubwo uduce duto tw'inzoga dushobora kuba ikibazo, kandi imikoranire ishobora kubaho amasaha menshi nyuma yo kunywa. Abantu bamwe bashobora kugira uduce duto cyane tw'inzoga zimwe na zimwe nka vodka cyangwa gin, ariko ibi bikorwa gusa hamwe n'ubuyobozi bwihariye bwa muganga wawe.

Uburyo bwiza ni ukwirinda inzoga rwose mugihe ufata phenelzine. Niba ukunda kunywa inzoga mu buryo bwo kwishimisha, ganira na muganga wawe ku bijyanye n'imiti igabanya ubwoba yindi ishobora kuba ifite umutekano wo gukoreshwa hamwe n'inzoga.