Ibipfunyiro by'amaso bya Physostigmine: Ibikoreshwa, Urutonde rw'imiti, Ingaruka ziterwa n'ibindi

Ibipfunyiro by'amaso bya Physostigmine ni umuti wandikirwa kugira ngo uvure indwara ya glaucoma n'izindi ndwara z'amaso ziteza umuvuduko mwinshi imbere mu maso yawe. Uyu muti ubarirwa mu itsinda ryitwa ababuza cholinesterase, bakora bafasha amazi kumeneka neza mu maso yawe kugira ngo bagabanye umuvuduko kandi barengere ijisho ryawe.

Tekereza amaso yawe nk'isabune amazi yinjiramo akagenda. Iyo umwobo ufunze igice, umuvuduko uriyongera. Physostigmine ifasha gufungura uwo mwobo kugira ngo amazi ameneke byoroshye, bigatuma umuvuduko uguma ku rwego rwiza.

Ibipfunyiro by'amaso bya Physostigmine ni iki?

Physostigmine ni ikinyabutabire gisanzwe cyakuwe mu gihingwa cyitwa Calabar. Iyo itegurwa nk'ibipfunyiro by'amaso, iba igikoresho gikomeye cyo gucunga indwara zimwe na zimwe z'amaso zigira ingaruka ku muvuduko imbere mu maso yawe.

Uyu muti ukora ubuza enzyme yitwa acetylcholinesterase. Iyo iyi enzyme yabuza, bituma imisemburo myinshi isanzwe yitwa acetylcholine iguma ikora mu bice by'amaso yawe. Ubu buryo bufasha sisitemu yo kumeneka kw'ijisho ryawe gukora neza.

Uyu muti ufashwe nk'ukomeye cyane ugereranije n'izindi miti ivura glaucoma. Muganga wawe azagenzura neza uko witwara kugira ngo yemeze ko bikora neza ku miterere yawe yihariye.

Ibipfunyiro by'amaso bya Physostigmine bikoreshwa kuri iki?

Ibipfunyiro by'amaso bya Physostigmine ahanini byandikirwa kuvura glaucoma, indwara aho umuvuduko wiyongera imbere mu maso yawe kandi ushobora kwangiza urugingo rw'amaso rwawe uko igihe kigenda. Uyu muti kandi ukoreshwa kuri hypertension y'amaso, bivuze umuvuduko mwinshi w'amaso nta kwangirika kw'imitsi bigaragara.

Muganga wawe ashobora kugusaba uyu muti niba ufite glaucoma ifunga urugingo, aho urugingo rwo kumeneka mu jisho ryawe rufunga. Rimwe na rimwe kandi bikoreshwa kuri glaucoma ifungura urugingo, ubwoko busanzwe aho kumeneka bigenda bigabanuka buhoro buhoro.

Mu buryo butajyenda cyane, amavuta yo mu maso ya physostigmine ashobora kwandikwa kugira ngo arwanye ingaruka z'imiti imwe n'imwe ishobora kwagura imboni cyane cyangwa ikatera izindi ngaruka zijyanye n'amaso. Muganga w'amaso yawe azagena niba uyu muti ukwiriye indwara yawe yihariye.

Physostigmine yo mu maso ikora ite?

Physostigmine ikora iteza imboni yawe ntoya kandi igahindura imiterere y'ibintu biri imbere mu jisho ryawe. Ibi bituma haboneka umwanya munini wo gukuramo amazi, bikagabanya umuvuduko ushobora kwangiza urugingo rw'amaso rwawe.

Uyu muti ufashwe nk'ukomeye cyane ugereranije n'ubundi buryo bwo kuvura glaucoma. Iyo ushyize amavuta mu maso yawe, atangira gukora mu minota nka 30, kandi ingaruka zirashobora kumara amasaha menshi.

Ijisho ryawe rifite uburyo bwo gukuramo amazi karemano bita trabecular meshwork. Physostigmine ifasha iyi sisitemu gukora neza cyane bitewe no gutuma imitsi imwe n'imwe yo mu jisho ryawe yikurura mu buryo bufungura inzira zo gukuramo amazi.

Nkwiriye gufata gute amavuta yo mu maso ya Physostigmine?

Buri gihe ukurikize amabwiriza yose ya muganga wawe yo gukoresha amavuta yo mu maso ya physostigmine. Muri rusange, uzashyira urutonyanga rumwe mu jisho ryagizweho ingaruka inshuro 2-4 ku munsi, ariko gahunda yawe yihariye yo gutanga imiti irashobora kuba itandukanye.

Mbere yo gushyira amavuta, oza intoki zawe neza n'isabune n'amazi. Canura umutwe wawe gato hanyuma ukureho gato uruhu rwo hasi rw'ijisho ryawe kugira ngo ukore umwanya muto. Suka urutonyanga rumwe muri uyu mwanya, hanyuma ufunge ijisho ryawe buhoro buhoro mu minota nka 1-2.

Ntukemere ko urutoki rw'agafuniko k'urutonyanga rukora ku jisho ryawe cyangwa ahantu hose kugira ngo wirinde kwandura. Nyuma yo gushyira amavuta, urashobora kurya bisanzwe kuko uyu muti ntusaba igihe cyihariye cyo kurya.

Niba ukoresha indi miti yo mu maso, tegera nibura iminota 5-10 hagati y'urutonyanga rutandukanye kugira ngo wirinde ko rushobora gukarabanwa. Muganga wawe azakubwira uburyo bwiza bwo gushyira imiti myinshi yo mu maso niba bibaye ngombwa.

Ndebera Igihe Nzagirira Amavuta yo mu Jisho ya Physostigmine?

Uko uvura amavuta yo mu jisho ya physostigmine biterwa n'uburwayi bw'ijisho ryawe ndetse n'uburyo umubiri wawe wakiriye imiti. Ku ndwara ya glaucome, ubu ni uburyo bwo kuvura burambye ushobora gukenera gukomeza igihe kirekire kugira ngo urinde amaso yawe.

Muganga wawe azajya akurikirana umuvuduko w'ijisho ryawe ndetse n'ubuzima bw'ijisho muri rusange, akenshi buri mezi make mbere, hanyuma bikagenda bigabanuka iyo uburwayi bwawe bumaze guhagarara. Ashobora guhindura gahunda yawe yo gufata imiti cyangwa agahindura imiti bitewe n'uburyo ubuvuzi burimo bukora.

Ntuzigere uhagarika gukoresha amavuta yo mu jisho ya physostigmine ako kanya utabanje kuvugana na muganga wawe. Guhagarara ako kanya bishobora gutuma umuvuduko w'ijisho ryawe wiyongera, bishobora gutera ibibazo byo kureba cyangwa izindi ngorane.

Ni Ibihe Bikorwa Bigaragara by'Amavuta yo mu Jisho ya Physostigmine?

Kimwe n'indi miti yose, amavuta yo mu jisho ya physostigmine ashobora gutera ibikorwa bigaragara, nubwo atari buri wese ubyumva. Ibikorwa bigaragara byinshi bifitanye isano n'amaso yawe kandi akenshi biba byoroheje kugeza hagati.

Dore ibikorwa bigaragara bisanzwe ushobora kubona:

• Urubavu mu jisho cyangwa kurishya iyo ubanje gushyira amavuta
• Kureba nabi, cyane cyane mu isaha ya mbere nyuma yo gukoresha amavuta
• Umutwe cyangwa kuribwa mu ruhanga
• Kwiruka kw'amaso cyangwa amaso arimo amazi
• Kugorana kureba ahantu hatagaragara cyangwa nijoro
• Abanyeshuri bato batagendana neza n'imihindagurikire y'umucyo

Ibi bikorwa bisanzwe akenshi biragenda bikosoka uko amaso yawe amenyera imiti mu byumweru bike bya mbere byo kuvura.

Ibikorwa bigaragara bikomeye ntibisanzwe ariko bisaba ubufasha bw'ubuvuzi bwihuse. Vugana na muganga wawe ako kanya niba ubonye urubavu rukomeye mu jisho, impinduka zidasanzwe zo kureba, ibimenyetso byo kwandura mu jisho (umutuku, ibyuka, kubyimba), cyangwa ibimenyetso bishobora kugaragaza ko imiti igira ingaruka ku bindi bice by'umubiri wawe.

Ingaruka zidakunze ariko zikomeye zishobora kugaragara mu mubiri harimo isesemi, kuruka, ibyuya byinshi, umutima utinda, cyangwa guhumeka bigoranye. Nubwo bitajyenda bibaho, ibi bimenyetso bishobora kwerekana ko umuti ushobora kugira ingaruka ku mubiri wawe wose kandi ugomba gusuzumwa na muganga vuba.

Ninde utagomba gukoresha amavuta yo mu maso ya Physostigmine?

Amavuta yo mu maso ya Physostigmine ntabwo akwiriye kuri buri wese. Muganga wawe azasuzuma neza amateka yawe y'ubuzima mbere yo kugutera uyu muti kugirango yemeze ko ari mutekanye kuri wowe.

Ntugomba gukoresha amavuta yo mu maso ya physostigmine niba ufite allergie ya physostigmine cyangwa ibindi bintu byose bikubiye muri uyu muti. Nanone irinde uyu muti niba ufite ubwoko runaka bwo mu maso (iritis cyangwa uveitis) cyangwa niba warabazwe mu maso vuba.

Abantu bafite indwara zimwe na zimwe z'umutima, asima, cyangwa ibibazo byo guhumeka bashobora gukenera kwirinda uyu muti cyangwa bakawukoresha bafite ubwitonzi bwinshi. Nibyo kandi niba ufite ibisebe byo mu gifu, umusonga ukabije, cyangwa indwara ya Parkinson.

Niba utwite cyangwa wonka, ganira ku ngaruka n'inyungu na muganga wawe. Nubwo umuti ushyirwa mu maso yawe, ibintu bito biracyinjira mu maraso yawe kandi bishobora kugira ingaruka ku mwana wawe.

Amazina y'ubwoko bw'amavuta yo mu maso ya Physostigmine

Amavuta yo mu maso ya Physostigmine aboneka mu mazina menshi y'ubwoko, nubwo uko aboneka bishobora gutandukana bitewe n'igihugu n'akarere. Mu turere tumwe na tumwe, ushobora kuyisanga igurishwa nka Eserine cyangwa mu yandi mazina yihariye.

Ubwoko busanzwe burimo ibintu bimwe bikora nk'ibicuruzwa by'amazina y'ubwoko kandi bikora neza. Farumasi yawe ishobora gusimbuza ubwoko busanzwe keretse muganga wawe asabye by'umwihariko izina ry'ubwoko.

Buri gihe jya ureba umufarmasi wawe niba wakira icupa ritandukanye n'uko risanzwe rimeze, kuko abakora bashobora guhindura ibikoresho cyangwa ushobora kwakira ubwoko busanzwe butandukanye.

Uburyo bwo gusimbuza amavuta yo mu maso ya Physostigmine

Niba amavuta yo mu maso ya physostigmine atagukwiriye, imiti myinshi isimbura irashobora kuvura glaucoma n'umuvuduko mwinshi wo mu maso. Muganga wawe ashobora gutekereza ku bintu bisa na prostaglandin nka latanoprost cyangwa travoprost, bikora mu buryo butandukanye ariko kandi bigafasha kugabanya umuvuduko wo mu maso.

Beta-blockers nka timolol ni ubundi buryo, cyane cyane kubantu batabasha kwihanganira ingaruka zo mu maso za physostigmine. Abahagarika carbonic anhydrase nka dorzolamide batanga ubundi buryo bwo kugabanya umuvuduko wo mu maso.

Kubantu bamwe, imiti ihuriweho irimo ubwoko bubiri butandukanye bwimiti ya glaucoma mu icupa rimwe irashobora kuba yoroshye kandi ikora neza kurusha amavuta y'ibintu byonyine.

Ese amavuta yo mu maso ya Physostigmine aruta Pilocarpine?

Physostigmine na pilocarpine byombi ni imiti ya cholinergic ikora kimwe kugabanya umuvuduko wo mu maso, ariko bifite itandukaniro rikomeye. Pilocarpine ikoreshwa cyane kandi imaze igihe kirekire iboneka, bituma iba ihitamo risanzwe kuri benshi mu baganga b'amaso.

Physostigmine ikunda gukora igihe kirekire kurusha pilocarpine, bishobora kuvuga ko ukeneye doze nkeya umunsi wose. Ariko, iki gikorwa kirekire gishobora kandi kuvuga ko ingaruka zikomeza igihe kirekire niba zibayeho.

Imiti yombi irashobora gutera ingaruka zisa nko kutabona neza no kugorana kubona ahantu hatagaragara. Muganga wawe azahitamo hagati yabo bitewe n'ibyo ukeneye, indi miti urimo gufata, n'uburyo wihanganira buri kimwe.

Ibikunze Kubazwa Kuri Amavuta yo mu maso ya Physostigmine

Ese amavuta yo mu maso ya Physostigmine aratekanye kuri diyabete?

Amavuta yo mu maso ya Physostigmine muri rusange afatwa nkatekanye kubantu barwaye diyabete, ariko muganga wawe azashaka kugukurikiranira hafi. Uyu muti ukora ahantu honyine mu maso yawe kandi ntugira ingaruka ku isukari yo mu maraso.

Ariko, abantu barwaye diyabete bafite ibyago byinshi byo kugira ibibazo by'amaso, bityo muganga wawe ashobora kwifuza kukubona kenshi kugira ngo arebe uko amaso yawe asubiza ku miti. Wibuke kuvuga icyemezo cyawe cya diyabete mugihe uvuga kubyerekeye uburyo bwo kuvura glaucoma.

Nkwiriye gukora iki niba nkoresheje amavuta y'amaso ya Physostigmine menshi?

Niba uteye amavuta menshi mu jisho ryawe, ntugahungabane. Koresha amazi meza cyangwa umuti wa saline mu jisho ryawe kugira ngo ukureho imiti yarenze urugero. Ushobora guhura n'ingaruka zikomeye nk'uko kubona bitagaragara neza cyangwa kutumva neza kw'ijisho.

Vugana na muganga wawe cyangwa umufarumasiti kugira ngo bagufashe, cyane cyane niba uhuye n'ibimenyetso bidasanzwe. Niba wamize umuti utabishaka cyangwa ukagira umubare munini mu maso yawe, shaka ubufasha bw'ubuvuzi vuba kuko ibi bishobora gutera ingaruka zikomeye.

Nkwiriye gukora iki niba nirengagije urugero rwa amavuta y'amaso ya Physostigmine?

Niba wirengagije urugero, uyashyireho vuba na bwangu uko wibuka, keretse igihe cyegereye urugero rwawe ruteganyijwe. Muri urwo rubanza, reka urugero rwarenganyijwe ukomeze gahunda yawe isanzwe.

Ntuzigere wongera urugero kugira ngo ugere ku rwarenganyijwe, kuko ibi bishobora kongera ibyago byo kugira ingaruka. Niba ukunda kwibagirwa urugero, tekereza gushyiraho ibyibutso kuri terefone cyangwa ukoreshe porogaramu ikurikirana imiti kugira ngo igufashe gukurikiza gahunda.

Nshobora guhagarika ryari gufata amavuta y'amaso ya Physostigmine?

Hagarika gusa gufata amavuta y'amaso ya physostigmine mugihe muganga wawe akubwiye ko byemewe kubikora. Kubantu benshi barwaye glaucoma, uyu muti ni uburyo bwo kuvura burambye bukenewe kugira ngo barengere icyerekezo uko imyaka igenda.

Muganga wawe ashobora gufata icyemezo cyo guhagarika umuti niba ugize ingaruka zitihanganirwa, niba ubuzima bwawe buhinduka, cyangwa niba bifuza kugerageza uburyo butandukanye bwo kuvura. Bazakurikirana umuvuduko w'ijisho ryawe hafi mugihe cyose cy'imiti kugira ngo barebe neza ko amaso yawe akomeza kuba mazima.

Nshobora gutwara imodoka nkanakoresha amavuta y'amaso ya Physostigmine?

Amasaro y'amaso ya Physostigmine ashobora kugira ingaruka ku miyoboro yawe, cyane cyane ubushobozi bwawe bwo kureba neza mu ntera zitandukanye no mu mucyo muke. Ushobora guhura no kutabona neza cyangwa kugorwa no guhuza n'imihindagurikire y'urumuri.

Irinde gutwara imodoka cyangwa gukoresha imashini kugeza umenye uko umuti ugira ingaruka ku miyoboro yawe. Abantu benshi basanga imiyoboro yabo ihinduka nyuma y'ibyumweru bike by'ubuvuzi, ariko bamwe bakomeza kugira impinduka zigaragara zisaba kwitonda buri gihe mu bikorwa bisaba kureba neza.