Pilocarpine ni iki: Ibyo ikoreshwa, urugero rwo gufata, ingaruka zabyo n'ibindi

Pilocarpine ni umuti wandikirwa na muganga ufasha umubiri wawe gukora amacandwe menshi n'amaso igihe ibintu bimwe na bimwe bitera umunwa wumye cyane cyangwa amaso yumye. Bifasha cyane abantu bafite imitsi ikora amacandwe idakora neza bitewe n'imiti cyangwa indwara ziterwa n'umubiri ubwawo.

Uyu muti ukora uhuza imitsi yihariye mu mubiri wawe igenzura imikorere y'amazi. Tekereza nk'uko uha imikorere yawe isanzwe ikora ububobere imbaraga zidasanzwe igihe zikeneye ubufasha bwihariye.

Pilocarpine ni iki?

Pilocarpine ni umuti ukora nk'umuti wa cholinergic agonist wigana ubutumwa bw'imiti karemano mu mubiri wawe bita acetylcholine. Ihereranye mu cyiciro cy'imiti yitwa parasympathomimetics, bisobanura ko ikora imikorere y'umubiri wawe yo

Indwara ya Sjögren ni indi mpamvu nyamukuru yo gukoresha uyu muti. Iyi ndwara y'ubwirinzi bw'umubiri ituma umubiri wawe wibasira imitsi ikora amacandwe n'amarira, bigatuma umubiri wumuka buri gihe, ibyo bikaba byagira ingaruka zikomeye ku buzima bwa buri munsi.

Mu buryo butajegajega, abaganga bashobora kwandika pilocarpine ku bantu bafite umunwa wumye uterwa n'imiti imwe n'imwe cyangwa indwara. Ariko, akenshi bikoreshwa mu gihe umunwa wumye cyane kandi izindi nshuti zitatanze ubufasha buhagije.

Pilocarpine ikora ite?

Pilocarpine ikora itegeka imitsi ya muscarinic mu macandwe yawe n'amaso. Iyo iyi mitsi ikoreshejwe, itera urukurikirane rw'ibikorwa bya selile bituma umubiri ukora amazi menshi.

Uyu muti ufashwe nk'ukomeye mu ngaruka zawo. Ntabwo itanga ubufasha bw'igihe gito nk'ibicuruzwa by'amacandwe y'ubwenge - ahubwo itera imitsi yawe gukora ibintu bisanzwe byinshi.

Uburyo butangira mu minota 20 nyuma yo gufata ikinini. Imitsi yawe itangira gukora amacandwe menshi, ashobora gukomeza amasaha menshi. Uburyo bumwe bukorerwa mu maso yawe, bufasha kugabanya amaso yumye.

Igituma pilocarpine ikora neza cyane ni uko ikora n'iyo imitsi yawe yangiritse. Igihe hari imitsi ikora, umuti ushobora kuyigira ngo ikore amazi menshi kuruta uko byagenda bisanzwe.

Nkwiriye gufata pilocarpine nte?

Fata pilocarpine nk'uko umuganga wawe abitegeka, akenshi inshuro eshatu ku munsi hamwe n'ibiryo. Kuyifata hamwe n'ibiryo bifasha kugabanya umujinya mu gifu kandi bituma umuti woroha.

Minya ikinini cyose hamwe n'ikirahure cy'amazi yuzuye. Ntukagure, ntukome, cyangwa uteme ikinini, kuko ibi bishobora kugira ingaruka ku buryo umuti winjizwa kandi bishobora kongera ingaruka ziterwa n'umuti.

Ni byiza gufata pilocarpine ku masaha amwe buri munsi kugira ngo urugero rwayo rukomeze kuba rumwe mu mubiri wawe. Abantu benshi babona ko bifasha gufata imiti ifatwa mu gitondo, ku manywa, no ku mugoroba kugira ngo bashyireho gahunda.

Menya neza ko wanyweye amazi ahagije mbere na nyuma yo gufata pilocarpine. Uyu muti ukora wongera umubiri gukora amazi, bityo kunywa amazi ahagije bishyigikira imikorere yawo kandi bifasha kwirinda kumuka amazi mu mubiri.

Nzamara Mfata Pilocarpine Igihe Kingana Gite?

Igihe cyo kuvura na pilocarpine gitandukana cyane bitewe n'uburwayi bwawe bw'ibanze n'uburyo wemera umuti. Abantu bamwe barawukeneye mu mezi make gusa, mu gihe abandi bashobora gukenera kuvurwa igihe kirekire.

Ku bafite umunwa wumye uterwa n'imirasire, kuvurwa birashobora kumara amezi menshi cyangwa igihe cyose. Imiyoboro yawe y'amacandwe ishobora gukira buhoro buhoro uko igihe gihita, bikakwemerera kugabanya cyangwa guhagarika umuti ukurikije ubuyobozi bwa muganga wawe.

Abantu bafite indwara ya Sjögren bakunze gukenera kuvurwa buri gihe kuko iyi ari indwara idakira. Ariko, muganga wawe azajya asuzuma buri gihe niba umuti ugikora neza bihagije kugira ngo ukomeze gukoreshwa.

Ntuzigere uhagarika gufata pilocarpine ako kanya utabanje kubaza muganga wawe. Nubwo itagira urugero, ibimenyetso byo kumuka k'umunwa wawe birashobora kugaruka vuba umaze guhagarika umuti.

Ni Iyihe Mico Mibi ya Pilocarpine?

Pilocarpine irashobora gutera imico mibi kuko igira ingaruka ku barese b'imitsi mu mubiri wawe wose, atari gusa mu miyoboro yawe y'amacandwe. Gusobanukirwa n'izi ngaruka zishobora kuba zizakufasha kumenya icyo witegura no kumenya igihe cyo kuvugana na muganga wawe.

Imico mibi isanzwe ni iyoroheje kandi akenshi irakosoka uko umubiri wawe wimenyereza umuti:

• Kubira ibyuya byinshi, cyane cyane ku ruhanga no ku ntoki
• Urugimbu cyangwa kutumva neza mu nda
• Umuzingo mu mazuru cyangwa kuziba kw'amazuru
• Kunyara kenshi
• Impiswi cyangwa kwituma bigoranye
• Kuribwa umutwe cyangwa kumva ureremba
• Kuribwa umutwe
• Kumva ushyushye cyangwa kumva ususumuka

Ibi bimenyetso bisanzwe bibaho kuko pilocarpine itera imikorere y'uturemangingo dusanzwe tuboneka mu tuyunguruzo tw'ibyuya, mu rwungano rw'igogora, n'izindi ngingo. Nubwo bitari byiza, akenshi birashoboka kubyitwaramo kandi bigenda bigabanuka uko igihe kigenda.

Ingaruka zikomeye ariko zitabaho kenshi zisaba ubufasha bwihutirwa bw'abaganga:

• Kugorwa cyane no guhumeka cyangwa guhumeka nabi
• Kubabara mu gituza cyangwa umutima wihuta
• Kubabara cyane mu nda cyangwa kuruka bidahagarara
• Ibimenyetso byo kumuka amazi mu mubiri nubwo wanywa amazi menshi
• Kutamenya neza ibintu cyangwa guhinduka mu mitekerereze
• Kuribwa umutwe cyane cyangwa kugwa igihumure

Izi ngaruka zikomeye ni gake zibaho ariko zishobora kubaho niba umuti wagize ingaruka ku rwungano rw'ubuhumekero cyangwa urwungano rw'imitsi y'umutima cyane. Niba ubonye kimwe muri ibi bimenyetso, gisha ubufasha bw'abaganga ako kanya.

Abantu bamwe bashobora kugira ingaruka zidasanzwe cyangwa zitabaho kenshi, harimo ibibazo byo kureba, guhinda umushyitsi kw'imitsi, cyangwa guhinduka kw'imitekerereze. Nubwo ibi bitari ibisanzwe, ni ngombwa kumenyesha muganga wawe ibimenyetso byose bibangamiye.

Ninde utagomba gufata Pilocarpine?

Abantu bamwe bagomba kwirinda pilocarpine kuko ishobora gutuma indwara zihari zirushaho cyangwa ikagirana imikoranire mibi n'ubuzima bwabo. Muganga wawe azasuzuma neza amateka yawe y'ubuzima mbere yo kugusaba uyu muti.

Abantu bafite ibi bibazo ntibagomba gufata pilocarpine:

• Asima idafashwe neza cyangwa ibibazo bikomeye byo guhumeka
• Glaucoma y'impande nto
• Indwara ikomeye y'umutima cyangwa umutima waherutse guhagarara
• Indwara ya peptic ulcer ikora
• Indwara ikomeye y'umwijima
• Amabuye mu mpyisi cyangwa kuziba kw'inzira y'inkari
• Allergie izwi kuri pilocarpine

Ibi bibazo bishobora guteza akaga iyo byishyize hamwe na pilocarpine kuko umuti ushobora gutuma ibibazo byo guhumeka birushaho kuba bibi, kongera umuvuduko mu jisho, cyangwa guteza izindi ngorane zikomeye.

Byongeye kandi, abantu bafite ibindi bibazo runaka bakeneye kwitonda cyane no gukurikiranwa hafi. Ibi birimo abafite asima yoroheje, ibibazo by'umutima bigenzurwa, indwara y'umwijima, cyangwa amateka y'amabuye mu mpyisi.

Abagore batwite kandi bonka bagomba kuganira ku byago n'inyungu na muganga wabo, kuko umutekano wa pilocarpine mugihe cyo gutwita utarashyirwaho neza. Uyu muti ushobora kujya mu mata y'ibere, bishobora kugira ingaruka ku bana bonka.

Amazina y'ubwoko bwa Pilocarpine

Pilocarpine iboneka munsi y'izina ry'ubwoko rya Salagen muri Leta Zunze Ubumwe z'Amerika. Ubu ni bwo buryo bwa pilocarpine buvugwa cyane mu kanwa bwo kuvura umunwa wumye n'amaso yumye.

Ubwoko bwa pilocarpine bwa generic buraboneka kandi bukora kimwe neza nk'ubwoko bw'izina. Farumasi yawe ishobora gusimbuza generic mu buryo bwikora keretse muganga wawe asabye by'umwihariko izina ry'ubwoko.

Birakwiye kumenya ko pilocarpine iboneka kandi nk'amatonyi y'amaso munsi y'amazina y'ubwoko butandukanye nka Isopto Carpine. Ariko, ibi bikoreshwa by'umwihariko mu kuvura glaucoma kandi ntibishobora gusimburana na tablet z'akanwa zikoreshwa mu kanwa k'umye.

Uburyo bwo gusimbuza Pilocarpine

Hariho ubundi buryo bwinshi bwo gusimbuza niba pilocarpine itagukwiriye cyangwa itatanga ubufasha buhagije. Guhitamo biterwa n'ikibazo cyawe cyihariye n'ubushobozi bwo kwihanganira imiti itandukanye.

Cevimeline (izina ry'ubwoko Evoxac) ni kimwe na pilocarpine. Ikora ikoreshwa kimwe ariko ishobora gutera ingaruka nke kuri bamwe, cyane cyane gucuruka guke no kuruka.

Ku birebana n'uburwayi bwo mu kanwa bworoheje, muganga wawe ashobora kugusaba gukoresha ibintu bitagomba kwandikwa na muganga. Ibi birimo ibicuruzwa by'amacandwe y'ubwoko bw'ubwoko, amazi yo mu kanwa yihariye, cyangwa chingamu zitagira isukari n'ibintu bishashagirana bishishikariza umubiri gukora amacandwe y'umwimerere.

Abantu bamwe bungukirwa no guhindura imibereho hamwe n'ubundi buvuzi. Ibi bishobora kuba birimo gukoresha imashini ituma umwuka uba mwiza, kunywa amazi menshi, kwirinda inzoga na kafeine, no gukora isuku nziza yo mu kanwa.

Mu gihe cy'uburwayi bukomeye aho imiti itagira akamaro, muganga wawe ashobora kuganira ku bindi bintu nka ibikoresho byo gushishikariza amacandwe cyangwa ndetse n'ibikorwa byo kubaga kugira ngo bifashe mu gusubiza ubushuhe.

Ese Pilocarpine iruta Cevimeline?

Bombi pilocarpine na cevimeline bifite akamaro mu kuvura umunwa wumye, ariko bafite imiterere itandukanye gato ituma imwe ikwiriye kuruta iyindi ku bantu bamwe.

Pilocarpine imaze igihe kinini iboneka kandi ifite ubushakashatsi bwinshi bushyigikira ikoreshwa ryayo. Akenshi ifatwa nk'ubuvuzi bwa mbere bw'umunwa wumye ukomeye uterwa na radiyo cyangwa indwara ya Sjögren.

Cevimeline ishobora gutera ingaruka nke, cyane cyane gusa umusembwa muke n'inda itari nziza. Abantu bamwe batabasha kwihanganira pilocarpine basanga cevimeline yoroshye gukoresha igihe kirekire.

Uburyo imiti yombi ikora muri rusange ni bumwe, nubwo ibisubizo by'umuntu ku giti cye bishobora gutandukana. Muganga wawe azatekereza ibimenyetso byawe byihariye, amateka yawe y'ubuvuzi, n'ubushobozi bwo kwihanganira ingaruka iyo uhitamo hagati yabo.

Ibikunze Kubazwa ku Pilocarpine

Ese Pilocarpine irakwiriye abarwayi ba diyabete?

Pilocarpine muri rusange irakwiriye abantu barwaye diyabete, ariko bisaba gukurikiranwa neza. Uyu muti ntugira ingaruka ku kigero cy'isukari mu maraso, ariko ushobora gutera umusembwa n'ibindi bimenyetso bishobora guhisha ibimenyetso by'isukari nkeya mu maraso.

Abantu barwaye diyabete bagomba gukurikirana isukari yabo mu maraso kenshi iyo batangira gufata pilocarpine, cyane cyane niba bagira ibyuya byinshi cyangwa isesemi. Izi ngaruka zishobora rimwe na rimwe kwitiranywa n'ibimenyetso bya hypoglycemia.

Muganga wawe ashobora gushaka gusuzuma gahunda yawe yo gucunga diyabete mbere yo kugutangira pilocarpine kugirango yemeze ko ushobora gutandukanya neza hagati y'ingaruka z'imiti n'imihindagurikire y'isukari mu maraso.

Nkwiriye gukora iki niba nanyweye pilocarpine nyinshi ku buryo butunguranye?

Niba unyweye pilocarpine nyinshi ku buryo butunguranye kurusha uko byategetswe, vugana n'umuganga wawe cyangwa ikigo gishinzwe ubumara ako kanya. Kubona urugero rwinshi rushobora gutera ibimenyetso bikomeye bisaba ubuvuzi.

Ibimenyetso byo kunywa pilocarpine nyinshi birimo ibyuya byinshi, isesemi ikabije no kuruka, guhumeka bigoranye, umuvuduko w'umutima utinda, no kuyoba. Ibi bimenyetso bishobora kuba byateza akaga kandi bishobora gusaba ubuvuzi bwihutirwa.

Ntugerageze kwivuza wenyine urugero rwinshi rw'umuti wo gutera kuruka cyangwa gufata indi miti. Ahubwo, shakisha ubufasha bw'ubuvuzi bw'umwuga ako kanya kandi uzane icupa ry'umuti kugirango werekane abaganga neza icyo wanyoye n'ingano yacyo.

Nkwiriye gukora iki niba nciwe urugero rwa pilocarpine?

Niba wibagiwe urugero rwa pilocarpine, rufate ako kanya wibuka, keretse igihe kigeze cyo gufata urugero rwawe ruteganyijwe. Muricyo gihe, reka urugero wibagiwe ukomeze gahunda yawe isanzwe.

Ntuzigere ufata urugero ebyiri icyarimwe kugirango usubize urugero wibagiwe. Ibi birashobora kongera ibyago byo kugira ingaruka ziterwa n'imiti hatabayeho inyungu yinyongera kubimenyetso byo kumva umunwa wumye.

Niba ukunda kwibagirwa urugero, tekereza gushyiraho ibyibutso kuri terefone cyangwa ukoreshe umuteguro w'ibinyobwa kugirango ugufashe kuguma ku murongo. Gufata imiti buri gihe ni ngombwa kugirango ugumane imikorere y'umuti.

Nshobora guhagarika ryari gufata pilocarpine?

Ugomba guhagarika gufata pilocarpine gusa uyobowe na muganga wawe. Igihe cyabyo giterwa n'uburwayi bwawe bw'ibanze n'uburyo ibimenyetso byawe bigenzurwa neza.

Kubera umunwa wumye uterwa n'imirasire, muganga wawe ashobora kugerageza kugabanya urugero buhoro buhoro kugira ngo arebe niba imitsi yawe yongera amavangingo yagaruye imikorere ihagije. Iyi nzira irashobora gufata amezi kugeza ku myaka nyuma yo kuvurwa n'imirasire.

Abantu bafite indwara ya Sjögren bashobora gukenera kuvurwa igihe cyose, nubwo muganga wawe azajya asuzuma niba umuti ugikora neza bihagije kugira ngo ukomeze gukoreshwa.

Nshobora kunywa inzoga niba mfata Pilocarpine?

Nibyiza kugabanya cyangwa kwirinda inzoga mugihe ufata pilocarpine. Inzoga irashobora gutuma ibimenyetso by'umunwa wumye birushaho kuba bibi kandi bishobora kongera ingaruka zimwe na zimwe z'umuti, cyane cyane isereri no kuruka.

Inzoga kandi ikora nka diuretic, ishobora guhangana n'ingaruka zimwe na zimwe za pilocarpine zitanga ubuhehere. Ibi bivuze ko ushobora kutabona inyungu zose z'umuti wawe niba unywa inzoga buri gihe.

Niba uhisemo kunywa inzoga rimwe na rimwe, bikore mu rugero kandi wibuke ko wihaza amazi menshi. Buri gihe ganira ku kunywa inzoga kwawe na muganga wawe kugira ngo batange inama zihariye zishingiye ku miterere yawe.