Icyo Prucalopride ari cyo: Ibikoreshwa, Urutonde rw'imiti, Ingaruka ziterwa n'iyo miti n'ibindi

Prucalopride ni umuti wandikirwa na muganga ufasha kuvura kubabara mu nda bya hato na hato binyuze mu gutuma amara yawe akora neza. Yagenewe by'umwihariko abantu batabonye umuti wundi w'uburwayi nk'ibyongerera imbaraga cyangwa imiti ikoreshwa ku isoko.

Uyu muti ubarirwa mu cyiciro cy'imiti yitwa serotonin receptor agonists, ikora ikoresha ibice byihariye mu igogora ryawe. Bitekereze nk'uko uha imitsi yawe y'amara akazi koroshye ariko gafite akamaro kugira ngo ibintu bikore neza.

Prucalopride ni iki?

Prucalopride ni umuti wihariye utuma amara yawe manini akora neza kugira ngo afashe kuvura kubabara mu nda bya hato na hato. Bitandukanye n'imiti isanzwe ikora mu igogora ryawe ryose, uyu muti wibanda by'umwihariko ku mara manini aho ibibazo byinshi byo kubabara mu nda bibera.

Uyu muti watejwe imbere nyuma y'imyaka myinshi yo gukora ubushakashatsi ku buryo igogora ryacu rivugana. Ikora ikoresha serotonin receptors mu mara yawe, zisa nk'ibishushanyo bibwira imitsi yawe y'amara igihe cyo kwikurura no gukura imyanda.

Ushobora kumenya uyu muti ku izina ry'ubucuruzi rya Motegrity muri Leta Zunze Ubumwe z'Amerika, cyangwa Resolor mu bindi bihugu. Yakoreshejwe neza i Burayi mu gihe kirenga imyaka icumi mbere yo kuboneka muri Amerika mu 2018.

Prucalopride ikoreshwa mu iki?

Prucalopride ikoreshwa cyane cyane mu kuvura kubabara mu nda bya hato na hato mu bantu bakuru. Ibi bivuze kubabara mu nda bya hato na hato bidafite impamvu isobanutse nk'ingaruka ziterwa n'imiti cyangwa izindi ndwara.

Muganga wawe ashobora kugusaba prucalopride niba umaze amezi cyangwa imyaka ufite kubabara mu nda, cyane cyane niba wagerageje izindi miti ntigire icyo itanga. Uyu muti ufasha cyane abantu bafite ibyago bike byo kwituma mu cyumweru cyangwa bahanganye n'imyanda ikomeye, igoye guca.

Ikoreshwa kandi igihe guhagarara k'umubiri kwawe bigira ingaruka zikomeye ku mibereho yawe, bigatera kutumva neza, kubyimba, cyangwa bikabangamira imirimo ya buri munsi. Uyu muti ushobora kuba ingirakamaro cyane cyane ku bantu bakuze bakunze kugira igogora ritinda uko imyaka yabo igenda yiyongera.

Prucalopride ikora ite?

Prucalopride ikora ikoresha imikorere y'uturemangingo twihariye twa serotonin twitwa 5-HT4 receptors mu mara yawe manini. Utu turemangingo dukora nk'ibishushanyo bya biyolojiya bigenzura uburyo imitsi yawe yo mu mara yihutisha kandi ikaruhuka.

Igihe ufata prucalopride, ifatana n'utu turemangingo ikohereza ibimenyetso bishishikariza imitsi ya colon yawe kwihutisha mu buryo bukurikiranwa nk'umuraba. Uyu murongo wa kamere, witwa peristalsis, ufasha gukura imyanda mu igogora ryawe neza.

Uyu muti ufatwa nk'ukomeye ku rugero ruciriritse ugereranije n'ibindi bisanzwe bigurishwa, ariko woroshye kurusha izindi nyunganizi zandikwa na muganga. Akenshi bitangira gukora mu masaha make, nubwo ushobora kutabona ingaruka zose mu minsi mike igihe igogora ryawe rimenyera imikorere y'uburyo bwiza.

Nkwiriye gufata Prucalopride nte?

Fata prucalopride nk'uko muganga wawe abikwandikiye, akenshi rimwe ku munsi mu gitondo. Urashobora kuyifata hamwe cyangwa utayifatanije n'ibiryo, nubwo abantu bamwe basanga kuyifata na saft ya mugitondo bifasha gushyiraho gahunda kandi bishobora kugabanya ibibazo byose byo mu nda.

Mimina urupapuro rwose hamwe n'ikirahure cy'amazi. Ntugasenye, uteme, cyangwa urume urupapuro, kuko ibi bishobora kugira ingaruka ku buryo umuti winjizwa kandi ukarekurwa mu mubiri wawe.

Niba ugitangira prucalopride, birafasha kuguma hafi y'ubwiherero mu minsi mike ya mbere igihe umubiri wawe wimenyereza umuti. Ingaruka zirashobora kugaragara cyane mu ntangiriro, ariko ibi akenshi biratuza igihe igogora ryawe ryimenyereza.

Gerageza gufata urugero rwawe ku gihe kimwe buri munsi kugira ngo ugumane urugero ruringaniye mu mubiri wawe. Gushyiraho umwanya wo kwibutswa kuri terefone birashobora kugufasha kwibuka, cyane cyane mu byumweru bya mbere byo kuvurwa.

Nzamara Igihe Kingana Gite Ndafata Prucalopride?

Igihe cyo kuvurwa na prucalopride gitandukanye bitewe n'uburyo umuntu ku giti cye abyitwaramo n'indwara yihishe. Abantu benshi bakeneye kuyifata buri gihe kugira ngo bagumane imyanya ya buri munsi, kuko guhura n'ikibazo cyo kutagira imyanya ya buri munsi kenshi bigaruka iyo umuti uhagaze.

Muganga wawe ashobora gushaka kukubona nyuma y'ibyumweru bya mbere kugira ngo amenye neza niba umuti ukora neza. Niba ubona ibisubizo byiza hamwe n'ingaruka zishobora gucungwa, urashobora gukomeza kuyifata igihe kirekire ukurikiranwa n'abaganga.

Abantu bamwe bashobora gushobora kugabanya urugero rwabo cyangwa guhagarika gufata umuti, cyane cyane niba bakoze impinduka mu mibereho yabo nko kongera kurya ibiryo birimo fibre, gukora imyitozo myinshi, cyangwa gukemura ibibazo by'ubuzima byihishe. Ariko, ntuzigere uhagarika cyangwa uhindura urugero rwawe utabanje kubiganiraho n'umuganga wawe.

Ni Iyihe Mbere Y'ingaruka Ziterwa na Prucalopride?

Kimwe n'imiti yose, prucalopride irashobora gutera ingaruka, nubwo atari buri wese uzibona. Ingaruka zisanzwe zifitanye isano n'inzira yawe yo gutunganya ibiryo kandi akenshi ziragabanuka uko umubiri wawe wimenyereza umuti.

Dore ingaruka zisanzwe zivugwa cyane zikora ku bantu benshi iyo batangira gufata prucalopride:

• Umutwe, akenshi ugabanuka nyuma y'icyumweru cya mbere
• Urugimbu cyangwa kutumva neza mu gifu, cyane cyane mu minsi ya mbere
• Impiswi cyangwa imyanya idakomeye uko umubiri wawe wimenyereza
• Urubavu mu gifu cyangwa kuribwa
• Kunanirwa cyangwa kumva unaniwe
• Umuzunguruko, cyane cyane iyo uhagurutse vuba

Izi ngaruka zisanzwe akenshi zigabanuka mu minsi mike cyangwa mu byumweru uko inzira yawe yo gutunganya ibiryo yimenyereza ingaruka z'umuti.

Ingaruka zitamenyerewe ariko zikomeye zikeneye ubufasha bwihuse bw'abaganga zirimo:

• Impiswi zikomeye cyangwa zihoraho ziteza umwuma
• Urubavu rukomeye rudakira
• Ibimenyetso byo kwibasirwa n'umubiri, nk'impyiko, kurigata, cyangwa kubyimba
• Impinduka zidasanzwe mu myifatire cyangwa imyitwarire
• Umutima utera cyane cyangwa mu buryo butunganye

Niba ubonye kimwe muri ibi bimenyetso bikomeye, vugana n'umuganga wawe ako kanya cyangwa ushake ubufasha bwihutirwa bw'ubuvuzi niba ibimenyetso bikomeye.

Ninde utagomba gufata Prucalopride?

Prucalopride ntabwo ikwiriye kuri buri wese, kandi muganga wawe azasuzuma neza amateka yawe mbere yo kuyandika. Uyu muti ntusabwa ku bantu bafite indwara zimwe na zimwe zo mu gifu cyangwa abafata imiti imwe.

Ntabwo ugomba gufata prucalopride niba ufite kimwe muri ibi bikurikira:

• Kubura inzira mu mara cyangwa indwara ikomeye yo mu mara
• Indwara ikomeye y'impyiko isaba dialysis
• Allergie izwi kuri prucalopride cyangwa ibiyigize
• Indwara ya Crohn cyangwa ulcerative colitis mu gihe ikora cyane
• Toxic megacolon cyangwa gutoboka kw'amara

Muganga wawe azitondera kandi kwandika prucalopride niba ufite ibibazo by'impyiko byoroheje, ufite imyaka irenga 65, cyangwa ufata imiti ishobora kugira ingaruka ku mutima wawe.

Abagore batwite cyangwa bonsa bagomba kuganira ku byago n'inyungu n'umuganga wabo, kuko hari amakuru make yerekeye umutekano muri ibi bihe. Uyu muti ushobora kujya mu mata y'ibere, bityo imiti isimbura ishobora gutekerezwa.

Amazina ya Prucalopride

Prucalopride iboneka mu mazina atandukanye bitewe naho utuye. Muri Leta Zunze Ubumwe z'Amerika, igurishwa nka Motegrity, izina rizwi cyane ku barwayi b'Abanyamerika.

Mu bindi bihugu, ushobora kubisanga ku izina rya Resolor, ryo ryari izina ry'ubucuruzi ryakoreshejwe bwa mbere ryemezwa mu Burayi. Iyi miti yombi ikubiyemo umuti umwe ukora kandi ikora kimwe.

Ibihugu bimwe bishobora kuba bifite ubwoko bwa generic, bukubiyemo umuti umwe ukora ariko bushobora kuba buhendutse. Buri gihe jya ubaza umuganga wawe w'imiti kugira ngo wemeze ko urimo gufata umuti ukwiye, hatitawe ku izina ry'ubucuruzi.

Uburyo bwo gusimbuza Prucalopride

Niba prucalopride itagukundiye cyangwa ikagutera ingaruka mbi, imiti myinshi isimbura irashobora kugufasha mu gihe cy'umwanya muremure w'umubabaro. Muganga wawe ashobora kugufasha kubona uburyo bukwiye bushingiye ku byo ukeneye byihariye n'amateka yawe y'ubuvuzi.

Iindi miti yandikwa na muganga ikora kimwe irimo:

• Lubiprostone (Amitiza), yongera amazi mu mara yawe
• Linaclotide (Linzess), ifasha mu kubana n'umubabaro wo mu nda no gufunga uruhu
• Plecanatide (Trulance), ikora yongera amazi mu mara
• Lactulose, umuti wo mu rwego rwo hejuru ukoreshwa igihe kirekire

Uburyo butandikwa na muganga muganga wawe ashobora gushyiraho harimo ibiyobyabwenge byongera imbaraga, ibituma umwanda woroha, cyangwa imiti ikoreshwa nka polyethylene glycol. Rimwe na rimwe uburyo bwo guhuza bukorera neza kuruta kwishingikiriza ku muti umwe.

Ese Prucalopride iruta Lubiprostone?

Prucalopride na lubiprostone zombi zikora neza mu gihe cy'umwanya muremure w'umubabaro, ariko zikora zinyuze mu buryo butandukanye kandi zishobora gukwira abantu batandukanye. Prucalopride itera imikorere y'amara mu buryo butaziguye, mugihe lubiprostone yongera amazi mu mara yawe kugirango yoroshye umwanda.

Prucalopride akenshi ikora vuba kandi ishobora gukora neza kubantu ikibazo cyabo gikomeye ari ukugenda gake kw'amara. Akenshi ifatwa rimwe ku munsi, ibintu benshi babona ko byoroshye kuruta lubiprostone ifatwa kabiri ku munsi.

Ariko, lubiprostone ishobora kwihanganirwa neza n'abantu bamwe, cyane cyane abagira isesemi ikomeye bafata prucalopride. Ikindi kandi, imaze igihe kinini iboneka kandi ifite amakuru menshi yerekeye umutekano wayo mu gihe kirekire.

Muganga wawe azatekereza ibintu nk'ibimenyetso byawe byihariye, imiti yindi ufata, n'amateka yawe y'ubuzima kugira ngo amenye uburyo bwiza bushobora kugukorera. Rimwe na rimwe bisaba kugerageza imiti itandukanye kugira ngo ubone iyikwiriye.

Ibibazo Bikunze Kubazwa Kuri Prucalopride

Ese Prucalopride irakwiriye ku bantu barwaye indwara z'umutima?

Prucalopride isaba kwitonderwa cyane ku bantu barwaye indwara z'umutima, cyane cyane abafite umutima utera nabi cyangwa guhagarara k'umutima bikomeye. Uyu muti ushobora kugira ingaruka ku mutima wa bamwe, nubwo bitajyenda bibaho.

Muganga wawe ashobora gushaka kureba uko umutima wawe umeze n'imiti ufata ubu mbere yo kugutera prucalopride. Ashobora kugusaba gukora electrocardiogram (EKG) kugira ngo arebe uko umutima wawe utera mbere yo gutangira kuvurwa, cyane cyane niba ufite amateka y'ibibazo by'umutima.

Niba ufite indwara y'umutima idakomeye kandi muganga wawe akemeza ko inyungu ziruta ibyago, birashoboka ko uzakenera gukurikiranwa cyane mugihe uvurwa. Buri gihe menyesha umuganga wawe ibimenyetso byose bifitanye isano n'umutima mugihe ufata prucalopride.

Nigute nzakora niba nanyweye prucalopride nyinshi bitunguranye?

Niba unyweye prucalopride nyinshi kuruta uko byategetswe, vugana na muganga wawe cyangwa ikigo gishinzwe kurwanya ubumara ako kanya, nubwo wumva umeze neza. Kunywa nyinshi bishobora gutera impiswi ikomeye, kumuka amazi, kandi bishobora guhindura mu buryo buteye akaga imiterere y'umubiri wawe.

Ntugerageze kwivuruguta niba utabitegetswe na muganga. Ahubwo, nywa amazi menshi kugira ngo ugume mu mazi kandi wigenzure niba hari ibimenyetso nk'imitsi ikomeye, impiswi ihoraho, isereri, cyangwa intege nke.

Niba wumva ibimenyetso bikomeye nk'umutima utera cyane, kugwa igihumure, cyangwa ibimenyetso byo kumuka amazi mu mubiri, genda vuba na vuba kwa muganga. Ujye ufata urupapuro rw'umuti kugira ngo abaganga babone neza icyo wafashe n'ingano yacyo.

Nkwiriye gukora iki niba nirengagije urugero rwa Prucalopride?

Niba wirengagije urugero rwa prucalopride, ujye urufata uko wibuka, keretse igihe cyo gufata urugero rukurikira kigeze. Mu gihe nk'icyo, ujye ureka urugero wirengagije ugakomeza gahunda yawe isanzwe yo gufata imiti.

Ntuzigere ufata urugero rurenze rumwe icyarimwe kugira ngo usimbure urugero wirengagije, kuko ibyo bishobora kongera ibyago byo kugira ingaruka z'uruhande nk'impiswi ikabije cyangwa kumuka amazi mu mubiri. Niba ukunda kwibagirwa urugero, tekereza gushyiraho alarme ya buri munsi cyangwa gukoresha umuteguro w'imiti kugira ngo bikugiremo urwibutso.

Kwirengagiza urugero rimwe na rimwe mubisanzwe ntizitera ibibazo, ariko gerageza kugira uburyo buhoraho kugira ngo ubashe kubona ibisubizo byiza. Niba wirengagije urugero rwinshi rukurikirana, ushobora kubona umubabaro wawe w'igifu ugaruka, kandi bishobora gufata iminsi mike kugira ngo wongere kugira imyitwarire isanzwe yo mu gifu.

Nshobora guhagarika ryari gufata Prucalopride?

Umwanzuro wo guhagarika prucalopride ugomba gufatirwa hamwe na muganga wawe, kuko guhagarika mu buryo butunguranye bishobora gutuma ibimenyetso by'umubabaro w'igifu bigaruka. Abantu benshi bafite umubabaro w'igifu uhoraho bakeneye kuvurwa igihe kirekire kugira ngo bagumane imyitwarire isanzwe yo mu gifu.

Muganga wawe ashobora gutekereza kugabanya urugero rwawe cyangwa guhagarika umuti niba umaze amezi menshi ugirana imyitwarire isanzwe yo mu gifu kandi wakoze impinduka zikomeye mu mibereho yawe. Ibi bishobora kuba birimo kongera imigozi y'ibiryo, gukora imyitozo buri gihe, cyangwa gukemura ibibazo by'ubuzima byihishe.

Niba wowe na muganga wawe mwemeje guhagarika prucalopride, mubisanzwe bikorwa buhoro buhoro aho gukorwa icyarimwe. Ibi bifasha sisitemu yawe yo mu gifu guhinduka kandi bigabanya amahirwe yo gusubira mu mubabaro w'igifu ako kanya. Ujye witegura ko ushobora kongera kuvurwa niba ibimenyetso bigarutse.

Nshobora gufata Prucalopride hamwe n'izindi miti ikurura?

Gufata prucalopride hamwe n'ibindi byongera imyanda mu mara bishobora kongera ibyago byo kuribwa, kumagara, no kutagira ibinyabutabire bikwiye mu mubiri. Muri rusange, muganga wawe azashaka ko uhagarika izindi nzitizi iyo utangiye prucalopride kugira ngo arebe uko ikora yonyine.

Niba umaze igihe ukoresha imiti yongera imyanda mu mara itangwa nta uruhushya, ntuyihagarike ako kanya mbere yo gutangira prucalopride utabanje kuvugana n'umuganga wawe. Bashobora kugusaba kugabanya buhoro buhoro izindi nzitizi uko prucalopride itangira gukora.

Mu bindi bihe, muganga wawe ashobora kugusaba gukoresha umuti woroshya imyanda mu mara hamwe na prucalopride, cyane cyane mu byumweru bya mbere by'ubuvuzi. Buri gihe banuza umuganga wawe mbere yo guhuza ubuvuzi ubwo aribwo bwose bwo kurwanya imyanda mu mara kugira ngo wemeze ko bifite umutekano ku miterere yawe yihariye.