Icyo Raloxifene ari cyo: Ibyo ikoreshwa, urugero rwo gufata, ingaruka zayo n'ibindi

Raloxifene ni umuti wandikirwa na muganga ufasha kurengera amagufa yawe no kugabanya ibyago byo kurwara indwara zimwe na zimwe nyuma yo gucura. Uyu muti ubarirwa mu cyiciro cy'imiti yitwa selective estrogen receptor modulators (SERMs), bivuze ko ishobora gukora nk'estrogen mu bice bimwe na bimwe by'umubiri wawe mugihe ibuza ingaruka za estrogen mu bindi bice.

Uyu muti ukoreshwa cyane cyane mu gukumira no kuvura osteoporosis ku bagore bamaze gucura, mugihe kandi utanga uburinzi ku ndwara ya kanseri y'ibere. Tekereza nk'uburyo bwihariye buguha bimwe mu byiza byo kurengera amagufa ya estrogen utongereye ibyago mu tundi duce nk'imitsi y'ibere.

Raloxifene ikoreshwa mu iki?

Raloxifene ifite impamvu ebyiri nyamukuru ku bagore bamaze gucura. Icya mbere, ifasha gukumira no kuvura osteoporosis mu gukomeza amagufa yawe no kugabanya ibyago byo kuvunika. Icya kabiri, irashobora kugabanya amahirwe yo kurwara kanseri y'ibere yinjira mu bindi bice by'umubiri.

Muganga wawe ashobora kukwandikira raloxifene niba ufite ibyago byinshi byo kurwara osteoporosis bitewe n'amateka y'umuryango, gucura kare, cyangwa kuvunika mbere. Bifatwa kandi niba ufite ibyago byinshi byo kurwara kanseri y'ibere ariko ntushobore gufata imiti yindi yo kuyirinda.

Uyu muti ukora neza cyane ku bagore bakeneye kurengerwa kw'amagufa ariko bifuza kwirinda ubuvuzi bwo gusimbuza imisemburo. Itanga inyungu zihariye aho uzikeneye cyane mugihe igabanya ingaruka zitifuzwa mu tundi duce tw'umubiri wawe.

Raloxifene ikora ite?

Raloxifene ikora mu kwigana ingaruka nziza za estrogen ku magufa yawe mugihe ibuza ingaruka zishobora kuba mbi ku gice cy'ibere n'umura. Ifatwa nk'umuti ukomeye w'urugero rwo hagati utanga uburinzi bw'ingirakamaro iyo ukoreshejwe buri gihe.

Mu magufwa yawe, raloxifene ifasha kubungabunga ubwinshi bw'amagufwa igabanya umuvuduko umubiri wawe usenya imitsi y'amagufwa. Iyi nzira ifasha kugumisha amagufwa yawe akomeye kandi igabanya ibyago byo kuvunika, cyane cyane mu mugongo no mu kibuno.

Muri icyo gihe, raloxifene ifunga imitsi yakira estrogen mu gice cy'ibere, ibyo bikaba bishobora gufasha kwirinda iterambere ry'ubwoko bumwe na bumwe bwa kanseri y'ibere. Iki gikorwa cyombi gituma iba uburyo bw'agaciro ku bagore bakeneye kurengerwa kw'amagufwa no kwirinda kanseri.

Nkwiriye Gufata Raloxifene Nte?

Fata raloxifene nk'uko byategetswe na muganga wawe, akenshi rimwe ku munsi igihe icyo aricyo cyose cy'umunsi. Urashobora kuyifata hamwe cyangwa utayifatanije n'ibiryo, kandi ntugomba guhangayika ku gihe cyo kuyifata n'ibiryo.

Mimina ikinini cyose hamwe n'ikirahure kinini cy'amazi. Ntugasenya, ntugacagagure, cyangwa ngo urume ikinini, kuko ibi bishobora kugira ingaruka ku buryo umuti ukora mu mubiri wawe.

Ni ngombwa gufata raloxifene hafi y'igihe kimwe buri munsi kugira ngo ugumane urwego ruzigama mu mubiri wawe. Abantu benshi basanga bifasha guhuza gufata imiti yabo n'akamenyero ka buri munsi, nk'ukoza amenyo cyangwa gufata ifunguro rya mu gitondo.

Menya neza ko ubona kalisiyumu ihagije na vitamine D mugihe ufata raloxifene, kuko izi ntungamubiri zikorera hamwe kugira ngo zishyigikire ubuzima bw'amagufwa. Muganga wawe ashobora kugusaba ibiyongera niba imirire yawe itatanga ibihagije.

Nkwiriye Gufata Raloxifene Igihe Kingana Gite?

Igihe cyo kuvura raloxifene gitandukanye bitewe n'ibyo ukeneye n'intego z'ubuzima bwawe. Abagore benshi bayifata imyaka myinshi kugira ngo babungabunge kurengerwa kw'amagufwa no kugabanya ibyago bya kanseri y'ibere.

Muganga wawe azagenzura buri gihe uko ugenda utera imbere binyuze mu igeragezwa ry'ubwinshi bw'amagufwa, ibizamini by'amaraso, n'ibizamini by'umubiri. Ibi bigenzura bifasha kumenya niba umuti ukora neza kandi niba ukwiriye gukomeza kuwufata.

Abagore bamwe bashobora gukenera gufata raloxifene imyaka myinshi, cyane cyane niba bafite ibyago bikomeje bya osteoporosis cyangwa kanseri y'ibere. Abandi bashobora guhindukira bakajya mu bindi byavurwa uko ubuzima bwabo buhinduka uko igihe kigenda.

Ntuzigere uhagarika gufata raloxifene ako kanya utabanje kubaza muganga wawe. Bazagufasha gukora gahunda izakomeza ubuzima bw'amagufa yawe n'uburinzi bwa kanseri niba ukeneye guhagarika umuti.

Ni Ibihe Bikorwa Bigaragara bya Raloxifene?

Abagore benshi bafata raloxifene neza, ariko nk'imiti yose, ishobora gutera ibikorwa bigaragara. Inkuru nziza ni uko ibikorwa byinshi bigaragara biba byoroheje kandi akenshi bikagenda neza uko umubiri wawe wimenyereza umuti.

Dore ibikorwa bigaragara bisanzwe ushobora guhura nabyo:

• Kugira ubushyuhe bwinshi no gucuruka
• Kuribwa amaguru, cyane cyane nijoro
• Kubyimba mu ntoki, ibirenge, cyangwa mu birenge
• Ibimenyetso bisa na gripe
• Kuribwa mu ngingo cyangwa gukakara
• Gucuruka cyane

Ibi bimenyetso mubisanzwe birashoboka kandi ntibisaba guhagarika umuti. Muganga wawe ashobora gutanga ibitekerezo byo kugabanya kutumva neza uko wimenyereza kuvurwa.

Nubwo bidakunze kubaho, abagore bamwe bashobora guhura n'ibikorwa bigaragara bikomeye bikeneye kwitabwaho:

• Kuribwa amaguru cyane cyangwa kubyimba
• Guhema nabi ako kanya
• Kuribwa mu gituza
• Kubabara umutwe cyane
• Guhinduka kw'amaso
• Kuva amaraso mu gitsina bidasanzwe

Vugana na muganga wawe ako kanya niba uhuye n'ikimenyetso icyo aricyo cyose muri ibi bikomeye, kuko bishobora kwerekana ingorane zikeneye ubufasha bwihuse bw'abaganga.

Hariho kandi akaga gato ariko k'ingenzi k'amaraso, cyane cyane mu maguru cyangwa mu muhaha. Iki kaga kiriyongera mu gihe cyo kutagira ubushobozi bwo kwimuka igihe kirekire, nk'urugendo rurerure cyangwa kuruhukira ku gitanda nyuma yo kubagwa.

Ninde Utagomba Gufata Raloxifene?

Raloxifene ntiriboneye kuri buri wese, kandi hari ibintu byinshi by'ingenzi bitagomba gukoreshwa. Muganga wawe azasuzuma neza amateka yawe y'ubuzima mbere yo kugutera uyu muti.

Ntabwo ukwiye gufata raloxifene niba:

• Utwite cyangwa ushobora gutwita
• Uri konjesha
• Utaranyura mu gihe cyo gucura
• Ufite amateka y'amaraso
• Ufite indwara y'umwijima ikora
• Ufite allergie kuri raloxifene cyangwa ibiyigize

Ibi bintu bitera impungenge z'umutekano zirenga inyungu zishoboka z'ubuvuzi. Muganga wawe azaganira ku zindi mpamvu niba raloxifene itagukwiriye.

Ibintu bimwe na bimwe by'ubuzima bisaba kwitonda cyane no gukurikiranwa neza:

• Amateka ya stroke cyangwa indwara y'umutima
• Umuvuduko w'amaraso uri hejuru
• Umuco wo kunywa itabi
• Kuruhuka igihe kirekire cyangwa kutagira ubushobozi
• Amateka yo gutera umutima bidahwitse
• Ibibazo by'impyiko cyangwa umwijima

Niba ufite kimwe muri ibi bintu, muganga wawe azagereranya ibyago n'inyungu neza mbere yo kugusaba raloxifene. Bashobora gutanga ibitekerezo byo gukurikiranwa kenshi cyangwa ubuvuzi bundi.

Amazina ya Raloxifene

Raloxifene iboneka munsi y'izina ry'ubucuruzi rya Evista mu bihugu byinshi. Iyi ni verisiyo isanzwe itangwa y'uyu muti kandi yigishijwe cyane ku mutekano no gukora neza.

Verisiyo rusange ya raloxifene nayo iraboneka kandi irimo ibintu bimwe bikora nk'umuti w'izina ry'ubucuruzi. Izi mpamvu rusange zikunze kuba zihenze kandi zitanga inyungu zingana.

Niba wakira raloxifene y'izina ry'ubucuruzi cyangwa rusange, umuti ukora kimwe. Umuganga wawe w'imiti ashobora kugufasha gusobanukirwa verisiyo wakira no gusubiza ibibazo byose bijyanye n'itandukaniro riri hagati y'uburyo bwo gukora.

Izindi mpamvu za Raloxifene

Imiti indi myinshi irashobora gufasha mu kurinda amagufa no gukumira kanseri y'ibere niba raloxifene itagukwiriye. Muganga wawe azatekereza ibyo ukeneye byihariye n'ubuzima bwawe muri rusange mugihe agena izindi nzira.

Mugukingira no kuvura indwara y'amagufa, izindi nzira zirimo:

• Bisphosphonates nka alendronate cyangwa risedronate
• Inshinge za Denosumab
• Teriparatide kubantu bafite indwara y'amagufa ikaze
• Ubuvuzi bwo gusimbuza imisemburo mubihe bimwe na bimwe

Mugukumira kanseri y'ibere, izindi nzira zirimo tamoxifen cyangwa aromatase inhibitors, bitewe n'ibintu bigushyira mu kaga n'amateka yawe y'ubuzima.

Buri nzira ifite inyungu zayo n'ingaruka zishobora kubaho. Muganga wawe azagufasha kugereranya izo nzira hanyuma ugatore ubuvuzi bukwiriye neza intego zawe z'ubuzima n'imibereho yawe.

Ese Raloxifene iruta Tamoxifen?

Raloxifene na tamoxifen byombi bifasha mugukumira kanseri y'ibere, ariko bikora mu buryo butandukanye kandi bifite ingaruka zitandukanye. Guhitamo hagati yabyo biterwa n'imibereho yawe n'ibyo ukeneye mubuzima.

Raloxifene irashobora gukundwa niba ukeneye gukingira amagufa no gukumira kanseri y'ibere, kuko itanga izo nyungu zombi mumuti umwe. Ifite kandi ibyago bike byo kurwara kanseri y'inkondo y'umura ugereranije na tamoxifen.

Tamoxifen irashobora guhitwamo niba uri umugore utarageza igihe cyo gucura cyangwa ufite ibyago byinshi byo kurwara kanseri y'ibere, kuko yemerewe gukoreshwa mubibazo byinshi. Ariko, ntigutanga inyungu zimwe zo kurinda amagufa nka raloxifene.

Muganga wawe azatekereza ibintu nk'imyaka yawe, uko wacuze, ubucucike bw'amagufa, n'ibyago bya kanseri mugihe agena uburyo bwiza kuri wewe. Imiti yombi yagaragaye ko ifite akamaro mubushakashatsi bunini bwakozwe.

Ibikunze Kubazwa Kuri Raloxifene

Ese Raloxifene irakwiriye kubantu barwaye indwara z'umutima?

Raloxifene ishobora gukoreshwa n'abagore benshi barwaye indwara z'umutima, ariko bisaba kwitondera no gukurikiranwa neza. Uyu muti ushobora gutanga akamaro ku mutima mu gufasha kugumana urugero rwiza rwa cholesterol.

Ariko, ibyago byo kuvura amaraso ni ikibazo ku bagore bafite indwara zimwe na zimwe z'umutima. Muganga w'umutima wawe n'umuganga wandika imiti bazakorana kugira ngo bamenye niba raloxifene ifite umutekano ku buzima bw'umutima wawe.

Nkwiriye gukora iki niba nanyweye raloxifene nyinshi bitunguranye?

Niba unyweye umuti mwinshi kuruta uko wategetswe, vugana n'umuganga wawe cyangwa ikigo gishinzwe kugenzura uburozi ako kanya. Nubwo ingaruka zikomeye zo kunywa umuti mwinshi zitaba kenshi, ni ngombwa kubaza inama ya muganga vuba.

Ntugerageze gusubiza umuti mwinshi wasubiyeho usiba doze yawe ikurikira. Ahubwo, kurikiza amabwiriza ya muganga wawe hanyuma usubire ku gahunda yawe isanzwe nkuko byategetswe.

Nkwiriye gukora iki niba nciwe doze ya raloxifene?

Niba uciwe doze, uyifate uko wibuka, keretse igihe cyo gufata doze yawe ikurikira kigeze. Muricyo gihe, siba doze waciwe hanyuma ukomeze gahunda yawe isanzwe.

Ntufate doze ebyiri icyarimwe kugira ngo usubize doze waciwe, kuko ibi bishobora kongera ibyago byo kugira ingaruka ziterwa n'umuti. Niba ukunda kwibagirwa doze, tekereza gushyiraho umwanya wo kwibutswa buri munsi cyangwa gukoresha igikoresho cyo gutegura imiti.

Nshobora kureka kunywa raloxifene ryari?

Umwanzuro wo kureka raloxifene ugomba gufatirwa hamwe na muganga wawe. Bazatekereza ubwinshi bw'amagufa yawe, ibyago bya kanseri y'ibere, n'ubuzima bwawe muri rusange mu gihe bamenya igihe cyiza cyo guhagarika imiti.

Abagore bamwe bashobora gukenera gukomeza kunywa raloxifene imyaka myinshi, mu gihe abandi bashobora kwimukira ku miti itandukanye uko ibyabo bihinduka. Muganga wawe azagufasha gukora gahunda izagufasha kugumana ubuzima bw'amagufa yawe no kurinda kanseri.

Nshobora gufata raloxifene hamwe n'indi miti?

Raloxifene ishobora kugirana imikoranire n’imiti imwe n’imwe, bityo ni ngombwa kubwira muganga wawe imiti yose n’ibiyobyabwenge ufata. Imikoranire imwe n’imwe ishobora kugira ingaruka ku buryo raloxifene ikora neza cyangwa ikongera ibyago byo kugira ingaruka ziterwa n’umuti.

Witondere imiti igabanya amaraso, kuko kuyihuza na raloxifene bishobora kongera ibyago byo kuva amaraso. Muganga wawe azahindura imipimo cyangwa agushakire izindi miti niba bibaye ngombwa kugira ngo umutekano wawe wizerwe.