Ramelteon ni iki: Ibikoresho, Uburyo bwo Gukoresha, Ingaruka Ziterwa n'ibindi

Ramelteon ni umuti wandikirwa ugufasha gusinzira ufasha mu gusinzira ukoresheje uburyo umubiri wawe usanzwe ukoresha mu gusinzira no kubyuka. Bitandukanye n'indi miti myinshi ifasha gusinzira, uyu muti wibanda cyane ku byakira bya melatonin mu bwonko bwawe, ibi bikaba bituma uba uburyo bwiza ku bantu bahanganye n'ibibazo byo kutagira ibitotsi.

Uyu muti ubarirwa mu cyiciro cy'ibintu byitwa melatonin receptor agonists, kandi wagenewe kwigana ingaruka za hormone yawe ya melatonin. Ushobora kuwumenya neza ku izina ry'ubucuruzi rya Rozerem, kandi bifasha cyane abantu bagira ibibazo byo gusinzira aho kuguma basinziriye.

Ramelteon ikoreshwa mu iki?

Ramelteon ikoreshwa cyane mu kuvura kutagira ibitotsi, cyane cyane ubwoko bw'aho ugira ibibazo byo gusinzira. Muganga wawe ashobora kugusaba uyu muti niba wibona uryamye igihe kirekire utarasinzira iyo ugiye kuryama.

Uyu muti ukora neza ku bantu bafite icyo bita

Tekereza melatonin nk'"ikimenyetso cy'uburwayi bwo gusinzira" karemano ry'umubiri wawe. Iyo umugoroba wegereye, ubwonko bwawe busanzwe butanga melatonin nyinshi, ibyo bikabwira umubiri wawe ko igihe kigeze cyo kwitegura gusinzira. Ramelteon mu by'ukuri yongera iki kimenyetso karemano mu gukoresha izo reseptori zimwe na zimwe melatonin yawe yagakoresheje.

Uyu muti ufatwa nk'ufasha gusinzira byoroheje kuko ukorana n'inzira zisanzwe z'umubiri wawe aho guhatira gusinzira binyuze mu gutuza. Bisaba iminota nka 30 kugeza ku isaha kugira ngo bitangire gukora, kandi ingaruka zabyo zirashobora kumara amasaha menshi.

Nkwiriye gufata Ramelteon nte?

Fata ramelteon nk'uko muganga wawe abikwandikiye, akenshi iminota nka 30 mbere yuko uteganya kuryama. Urutonde rusanzwe ni 8 mg, ifatwa rimwe ku munsi, ariko muganga wawe azagena umubare ukwiye w'ikibazo cyawe.

Ukwiriye gufata uyu muti ku gifu cyambaye ubusa cyangwa ufatanije n'akantu gato. Irinde kuwufata hamwe cyangwa nyuma gato y'ifunguro ririmo amavuta menshi, kuko ibi bishobora gutuma umuti ukora gahoro. Ifunguro riremereye rishobora gutinda imitsi ya ramelteon kugeza ku isaha.

Egera ko ufite byibura amasaha 7 kugeza ku 8 yo gusinzira mbere yo gufata ramelteon. Kuwufata igihe utabona umwanya wo kuruhuka ijoro ryose bishobora gutuma wumva urushye umunsi ukurikira. Nanone, irinda inzoga iyo ufata uyu muti, kuko bishobora kongera uburwayi no kugabanya imikorere y'umuti.

Nkwiriye kumara igihe kingana iki mfata Ramelteon?

Igihe cyo kuvura na ramelteon gitandukana bitewe n'ikibazo cyawe bwite n'icyo muganga wawe agusaba. Abantu bamwe barawukoresha mu byumweru bike kugira ngo banyure mu gihe gihangayikishije, mu gihe abandi bashobora kuwufata mu mezi menshi.

Bitandukanye n'imiti imwe yo gusinzira, ramelteon ntisanzwe itera kwishingikiriza ku mubiri, bivuze ko bidashoboka ko waba ufite ibimenyetso byo gukurwaho iyo uhagaritse kuyifata. Ariko, ugomba gukorana na muganga wawe kugira ngo umenye igihe cyiza cyo kuvurwa kwawe.

Muganga wawe ashobora gutanga igitekerezo cyo gutangira igeragezwa rito kugira ngo urebe uko umuti ukora neza kuri wowe. Niba bifasha kandi niba nta ngaruka mbi zigutera, bashobora kugusaba gukomeza kuyifata igihe kirekire. Kugenzura buri gihe n'umuganga wawe bizafasha kumenya niba umuti ukomeza kuba wo guhitamo neza kuri wowe.

Ni izihe ngaruka ziterwa na Ramelteon?

Abantu benshi bakira neza ramelteon, ariko nk'undi muti uwo ari wo wose, ushobora gutera ingaruka. Inkuru nziza ni uko ingaruka zikomeye zitaba kenshi, kandi abantu benshi bagira ingaruka zoroheje zikagenda zikira uko umubiri wabo umenyera umuti.

Dore ingaruka zisanzwe ushobora kugira:

• Gusinzira ku manywa cyangwa kunanirwa
• Kuribwa umutwe, cyane cyane iyo uhagurutse vuba
• Urugimbu cyangwa kuribwa mu nda
• Kuribwa umutwe
• Kuzamba kw'ibibazo byo kutabona ibitotsi mu bihe bimwe
• Inzozi zidasanzwe cyangwa zigaragara neza
• Kugabanuka koroheje kw'ibyiyumvo cyangwa impinduka z'imitekerereze

Izi ngaruka zisanzwe zikunda gushira mu minsi mike kugeza ku cyumweru umubiri wawe umaze kumenyera umuti. Niba zikomeje cyangwa zikaba zikubangamiye, menyesha muganga wawe kugira ngo ashobore guhindura gahunda yawe yo kuvurwa.

Hariho kandi ingaruka zimwe zitaba kenshi ariko zikomeye ugomba kumenya. Nubwo ibi bitaba ku bantu benshi, ni ngombwa kubimenya:

• Uburwayi bukomeye bwo kwibasirwa n'ibintu bitera allergie bifatanye no kubyimba mu maso, iminwa, cyangwa umuhogo
• Imyitwarire igoye yo gusinzira nk'ukugenda mu nzozi cyangwa gutwara imodoka usinziriye
• Kugabanuka kw'agahinda cyangwa ibitekerezo byo kwiyahura
• Urugero rwo kuribwa umutwe cyangwa kuvurungana
• Impinduka za hormone, cyane cyane zireba urugero rwa testosterone
• Ibibazo by'umwijima, nubwo bidasanzwe cyane

Niba ubonye bimwe muri ibi bimenyetso bikomeye, vugana n'umuganga wawe ako kanya cyangwa ushake ubufasha bw'ubuvuzi bwihutirwa. Abantu benshi ntibahura n'ibi bibazo, ariko kumenya biragufasha kuguma mu mutekano.

Ninde utagomba gufata Ramelteon?

Ramelteon ntabwo ikwiriye kuri buri wese, kandi hariho ibintu byinshi aho umuganga wawe ashobora kugusaba undi muti wo gusinzira. Umutekano wawe niwo uza imbere, bityo ni ngombwa kuganira ku mateka yawe y'ubuvuzi mbere yo gutangira ubu buvuzi.

Ntabwo ugomba gufata ramelteon niba ufite indwara ikomeye y'umwijima cyangwa kunanirwa kw'umwijima. Umwijima wawe ukoresha uyu muti, kandi niba utari gukora neza, ramelteon irashobora kwiyongera mu buryo buteye akaga mu mubiri wawe. Ndetse n'ibibazo byoroheje by'umwijima bishobora gusaba guhindura urugero rw'umuti cyangwa ubundi buvuzi.

Abantu bafata imiti imwe n'imwe bagomba kandi kwirinda ramelteon. Ibi birimo ibintu bikomeye bya CYP1A2 nka fluvoxamine, bishobora kongera cyane urugero rwa ramelteon mu maraso yawe. Niba ufata rifampin cyangwa indi miti igira ingaruka ku enzymes z'umwijima, umuganga wawe azakenera gusuzuma neza niba ramelteon ikwiriye kuri wowe.

Abagore batwite kandi bonka bagomba muri rusange kwirinda ramelteon keretse inyungu zigaragara neza kurusha ibyago. Uyu muti ushobora kwinjira mu mata y'ibere, kandi ingaruka zawo ku bana bakiri bato ntizisobanukiwe neza. Buri gihe ganira ku migambi yawe yo gutwita cyangwa uko utwite ubu n'umuganga wawe.

Abana n'urubyiruko bari munsi y'imyaka 18 ntibagomba gufata ramelteon, kuko umutekano wayo n'ubushobozi bwayo bitarashyirwaho mu byiciro by'imyaka mito. Abantu bakuze bashobora gukenera doze ntoya cyangwa gukurikiranwa neza kubera ko imiti itunganywa gahoro.

Amazina ya Ramelteon

Ramelteon izwi cyane ku izina ryayo rya Rozerem, ikorwa na Takeda Pharmaceuticals. Iri ni izina ry'umwimerere ry'ubwoko bwa mbere umuti wemerejwe kandi ukagurishwa.

Muri iki gihe, Rozerem ni izina ry'ingenzi uzasanga muri farumasi nyinshi no mu bigo by'ubuvuzi. Ubwoko bwa ramelteon bwa generic buraboneka kandi, burimo ibintu bimwe bikora ariko bishobora kuva mu nganda zitandukanye kandi akenshi bihendutse kurusha ubwoko bw'izina ry'ubwoko.

Iyo muganga wawe yanditse ramelteon, ashobora kwandika izina rya generic cyangwa izina ry'ubwoko ku byanditswe byawe. Umufarumasiti wawe ashobora kugufasha gusobanukirwa niba urimo kubona ubwoko bw'izina ry'ubwoko cyangwa generic, kandi byombi bikwiye gukora neza kubijyanye n'ibibazo byo gusinzira.

Uburyo bwa Ramelteon

Niba ramelteon itagukorera neza cyangwa ikaba itera ingaruka zikubangamiye, hari ubundi buryo butandukanye muganga wawe ashobora gutekereza. Buri buryo butandukanye bukora mu buryo butandukanye, bityo kubona icyo gikwiriye akenshi bikubiyemo kugerageza uburyo butandukanye.

Melatonin supplements ni uburyo bwa kamere abantu benshi bagerageza mbere. Nubwo biboneka hanze ya counter, ntibihujwe nkuko ramelteon yanditswe, kandi imikorere yabo irashobora gutandukana. Abantu bamwe babona ko bifasha kubibazo byoroheje byo gusinzira cyangwa jet lag.

Izindi miti yo gusinzira yanditswe harimo zolpidem (Ambien), eszopiclone (Lunesta), na zaleplon (Sonata). Iyi miti ikora mu buryo butandukanye na ramelteon mugukora kuri GABA receptors mu bwonko bwawe. Bakunda gukora vuba ariko bashobora kugira ibyago byinshi byo kwishingikiriza no kumva umunaniro mu gitondo.

Suvorexant (Belsomra) ni ubundi buryo bushya bukora buhagarika imitsi ya orexin, ifite uruhare mu gukanguka. Kimwe na ramelteon, yagenewe gukora hamwe n'inzira yawe isanzwe yo gusinzira aho guhatira umuntu gusinzira.

Uburyo butakoresha imiti nabwo bukwiye kuzirikwa. Ubuvuzi bw'imyitwarire ku bantu bagira ikibazo cyo kutabona ibitotsi (CBT-I) bufite ubushakashatsi bufatika kandi bushobora gutanga inyungu zirambye. Gukora isuku ku buryo bwo gusinzira, uburyo bwo kuruhuka, no gukemura umunabi cyangwa guhangayika byose bishobora gufasha kunoza imiterere yo gusinzira.

Ese Ramelteon iruta Melatonin?

Ramelteon na melatonin supplements bikora ku nzira zisa mu bwonko bwawe, ariko hariho itandukaniro rikomeye rishobora gutuma imwe ikwiriye kurusha iyindi kubera uko ubuzima bwawe bumeze.

Ramelteon ni umuti wandikirwa na muganga wagenewe kandi wagenzurwa by'umwihariko mu kuvura kutabona ibitotsi. Iruta kandi irakora neza kurusha melatonin supplements itangwa itagombye uruhushya rwa muganga, kandi yanyuze mu igeragezwa ryo kwa muganga ryo kugaragaza umutekano wayo n'ubushobozi bwayo.

Melatonin supplements itangwa itagombye uruhushya rwa muganga zitandukanye cyane mu miterere n'urugero. Ibicuruzwa bimwe birimo melatonin nyinshi cyangwa nkeya kurusha uko byanditseho, kandi igihe ibyo bikora bishobora kuba bitagaragara. Ramelteon, kuba ari umuti wandikirwa na muganga, ifite igenzura rikomeye ry'imikorere n'urugero rukomeye.

Kubibazo byoroheje, rimwe na rimwe byo gusinzira cyangwa jet lag, melatonin supplements birashobora guhaga kandi birahendutse. Ariko, niba ufite kutabona ibitotsi bihoraho bikagira ingaruka zikomeye ku buzima bwawe bwa buri munsi, ingaruka zizewe za ramelteon n'ubuyobozi bwa muganga birashobora kuba bikwiriye amafaranga menshi n'imbaraga.

Muganga wawe ashobora kugufasha gupima ibyiza n'ibibi bya buri kimwe hashingiwe ku buryo bwawe bwo gusinzira, imiti yindi urimo gufata, n'ubuzima bwawe muri rusange. Rimwe na rimwe abantu batangirana na melatonin supplements hanyuma bakajya kuri ramelteon niba bakeneye ikintu gikomeye.

Ibikunze Kubazwa Kuri Ramelteon

Ikibazo cya 1. Ese Ramelteon irakoreshwa neza igihe kirekire?

Ramelteon isa nkaho ikoreshwa neza igihe kirekire kurusha imiti myinshi yo gusinzira kuko ntiteranya umubiri cyangwa ngo itere kwihanganira. Ubushakashatsi bwagaragaje ko abantu bashobora kuyifata amezi menshi batagomba gukoresha doze nyinshi kugira ngo bakomeze gukora neza.

Ariko, gukoresha igihe kirekire buri gihe bigomba kugenzurwa na muganga wawe. Bazashaka kureba uko umuti ukomeza kugukorera neza no kureba niba hari ingaruka zigaragara. Kugenzura buri gihe bifasha kumenya niba ramelteon ikomeza kuba amahitamo meza ku bibazo byawe byo gusinzira.

Ikibazo cya 2. Nkwiriye gukora iki niba mfashe ramelteon nyinshi ku buryo butunganye?

Niba ufata ramelteon nyinshi ku buryo butunganye kuruta uko byategetswe, vugana na muganga wawe cyangwa ikigo gishinzwe kurwanya ubumara ako kanya. Nubwo kwirenza doze bidakunze kubaho, gufata nyinshi bishobora gutera gusinzira cyane, urujijo, cyangwa ibindi bimenyetso biteye inkeke.

Ntugerageze kuguma maso cyangwa kunywa cafeine kugira ngo urwanye ingaruka. Ahubwo, jya ahantu hizewe ushobora kuruhukira kandi ufite umuntu ukugenzura. Niba urimo guhura n'ibimenyetso bikomeye nk'ingorane zo guhumeka cyangwa urujijo rwinshi, shakisha ubuvuzi bwihutirwa ako kanya.

Ikibazo cya 3. Nkwiriye gukora iki niba ntashe doze ya ramelteon?

Niba utashye doze yawe ya ramelteon yo kujya kuryama, uyirengagize gusa maze ufate doze yawe ikurikira ku gihe gisanzwe mu ijoro rikurikira. Ntukafate doze ebyiri kugira ngo usubize iyatakaye, kuko ibi bishobora kongera ibyago byo kugira ingaruka.

Gufata ramelteon hagati mu ijoro cyangwa mu gitondo kare bishobora gutuma wumva unanutse umunsi ukurikira. Biruta kugira ijoro rimwe rishobora kugorana gusinzira kuruta gushyira mu kaga kunanuka k'umunsi ukurikira biturutse ku miti itafashwe neza.

Ikibazo cya 4. Nshobora kureka gufata ramelteon ryari?

Ubusanzwe ushobora kureka gufata ramelteon igihe wowe na muganga wawe mwemeranyije ko gusinzira kwawe kwateye imbere bihagije ku buryo utakigomba ubufasha bw'imiti. Bitandukanye n'imiti imwe yo gusinzira, ramelteon ntisanzwe isaba inzira yo kugabanya buhoro buhoro.

Igihe cyo gufata imiti kiratandukana ku muntu ku muntu. Abantu bamwe bakoresha ramelteon mu byumweru bike gusa kugira ngo banyure mu bihe birimo stress, mu gihe abandi bashobora kungukirwa no kuyifata igihe kirekire. Muganga wawe azagufasha kumenya igihe witeguye kugerageza gusinzira udafata imiti.

Q5. Nshobora gufata Ramelteon hamwe n'indi miti?

Ramelteon ishobora gukururana n'indi miti myinshi, bityo ni ngombwa kubwira muganga wawe ibyo ufata byose, harimo imiti igurishwa itagomba uruhushya rwa muganga n'ibiribwa byongera imbaraga. Imiti imwe ishobora gutuma ramelteon itagira akamaro, mu gihe indi ishobora kongera ingaruka zayo ku buryo bushobora guteza akaga.

Imiti igabanya ubwoba, imiti ituma amaraso atavura vuba, na antibiyotike zimwe na zimwe ni zimwe mu miti ishobora gukururana na ramelteon. Muganga wawe azasuzuma urutonde rw'imiti yose ufata kandi akore impinduka zose zikenewe kugira ngo akurinde mu gihe avura ibibazo byawe byo gusinzira neza.