Icyo Ranibizumab ari cyo: Ibyo ikoreshwa, Urutonde rw'imiti, Ingaruka zayo n'ibindi

Ranibizumab ni umuti wandikirwa na muganga, abaganga bawutera mu jisho kugira ngo bavure ibibazo bimwe na bimwe byo mu jisho. Ni umuti wihariye ufasha kurengera rimwe na rimwe akanongera ubushobozi bwo kureba iyo indwara zimwe na zimwe zo mu jisho ziteje ibibazo mu kureba.

Ubu buvuzi bushobora kumvikana nk'ubwoba mu ntangiriro, ariko mu by'ukuri ni ubuvuzi bwemejwe neza bwafashije abantu babarirwa muri za miriyoni ku isi hose kubungabunga ubushobozi bwabo bwo kureba. Kumva uko ikora n'icyo witegura bishobora kugufasha kumva ufite icyizere cyinshi kuri ubu buryo bwo kuvura.

Ranibizumab ni iki?

Ranibizumab ni ubwoko bw'umuti bita VEGF inhibitor, bivuze ko ibuza poroteyine itera imitsi idasanzwe gukura mu jisho ryawe. Tekereza nk'ubuvuzi bugamije bugana mu nkomoko y'ikibazo muri retine yawe.

Uyu muti uza mu iseswa risobanutse muganga wawe w'amaso ateramo mu vitreous, ari yo kintu gisa na jeli cyuzura imbere y'ijisho ryawe. Ubu buryo bwo gutanga umuti butuma umuti ugera neza aho ukenewe cyane.

Muganga wawe azakoresha urushinge ruto cyane kuri iyi nshinge, kandi ubu buryo busanzwe bufata iminota mike gusa. Uyu muti ukora mu jisho ryawe kugira ngo uvure indwara yateje ibibazo byo mu kureba.

Ranibizumab ikoreshwa mu kuvura iki?

Ranibizumab ivura indwara zikomeye zo mu jisho zishobora guteza ibibazo mu kureba. Impamvu isanzwe abaganga bawandikira ni ugusaza kwa macula, cyane cyane ubwoko bwa

Uyu muti ufasha kandi abantu bafite indwara ya diyabete yibasira ururenda rw'ijisho, ikibazo cya diyabete cyangiza imitsi y'amaraso mu rurenda rw'ijisho. Byongeye kandi, uvura ububyimbirwe bwo mu rurenda rw'ijisho nyuma yo kuziba kw'umutsi w'amaraso wo mu rurenda rw'ijisho, bibaho iyo umutsi w'amaraso wo mu rurenda rw'ijisho ryawe wifunze.

Mu bindi bihe, abaganga bakoresha ranibizumab ku zindi ndwara zo mu rurenda rw'ijisho aho imitsi y'amaraso idasanzwe ikura cyangwa amazi yiyongera bikabangamira iyerekwa ryawe. Umuganga w'amaso wawe azemeza niba ubu buvuzi bukwiye kuri wowe.

Ranibizumab ikora ite?

Ranibizumab ikora ibuza poroteyine yitwa VEGF umubiri wawe ukora iyo utekereza ko ururenda rw'ijisho rwawe rukeneye imitsi y'amaraso myinshi. Mugihe iyi poroteyine ifite imirimo y'ingenzi, nyinshi cyane zirashobora gutera ibibazo mu jisho ryawe.

Iyo urwego rwa VEGF ruzamutse cyane, rushobora gutera imitsi y'amaraso idasanzwe, ivamo amazi menshi mu rurenda rw'ijisho ryawe. Iyi mitsi akenshi ivamo amazi cyangwa amaraso, bishobora gutuma iyerekwa ryawe ritagaragara neza cyangwa bigatuma habaho ahantu hatagaragara neza mu iyerekwa ryawe ryo hagati.

Mugihe ibuza VEGF, ranibizumab ifasha kwirinda imitsi y'amaraso mishya idasanzwe ikura kandi irashobora gutuma imitsi ifite ibibazo yenda gushiriramo. Ibi bigabanya kuvamo amazi menshi kandi bifasha kubungabunga iyerekwa ryawe risigaye.

Uyu muti ufashwe nk'uvura ku rugero rwo hagati kugeza ku rwo hejuru ukora mu buryo butaziguye ku rwego rw'uturemangingo. Yagenewe by'umwihariko kugirango yite ku ndwara itabangamiye ibindi bice by'umubiri wawe cyane.

Nkwiriye gufata ranibizumab nte?

Ranibizumab ihabwa buri gihe nk'urushinge mu jisho ryawe n'umuganga w'amaso wujuje ibisabwa mu mavuriro. Ntushobora gufata uyu muti mu rugo, kandi bisaba ibikoresho byihariye n'ubumenyi kugirango utange neza.

Mbere yo guterwa urushinge, umuganga wawe azahumuriza ijisho ryawe n'amatonyi yihariye kugirango agabanye kutumva neza. Bazanamesa neza ahantu hakikije ijisho ryawe kugirango birinde kwandura. Urukinge nyarwo rufata amasegonda make, nubwo gahunda yose ishobora kumara iminota 30 kugeza ku isaha.

Ntugomba kwiyiriza ubusa cyangwa kwirinda kurya mbere yo guterwa urushinge rwa ranibizumab. Ariko, ugomba guteganya umuntu uzakujyana mu rugo, kuko iyerekwa ryawe rishobora guhinduka by'agateganyo cyangwa ukagira ibibazo gato nyuma yo guterwa urushinge.

Nyuma yo guterwa urushinge, muganga wawe ashobora kuguha amavuta yo mu maso arwanya mikorobe kugira ngo wirinde indwara. Kurikiza amabwiriza yabo neza yerekeye igihe n'uburyo bwo gukoresha aya mavuta, kuko kwitabwaho neza nyuma y'ubuvuzi ni ngombwa kugira ngo ubashe kubona ibisubizo byiza.

Nzamara Igihe Kingana Gite Nkoresha Ranibizumab?

Igihe cyo kuvurwa na ranibizumab gitandukanye cyane bitewe n'uburwayi bwawe bwihariye n'uburyo wemera imiti. Abantu benshi bakeneye kuvurwa buri gihe mu mezi cyangwa imyaka kugira ngo bagumane iyerekwa ryabo ryiza.

Mubisanzwe, uzatangira guterwa inshinge buri kwezi mu mezi make ya mbere. Muganga wawe azakurikirana neza uko urimo urivura muri iki gihe cya mbere kugira ngo arebe uko ubuvuzi burimo bugukorera.

Nyuma y'uruhererekane rwa mbere, abantu benshi bashobora kongera igihe hagati y'inshinge buri mezi abiri cyangwa atatu. Abantu bamwe bashobora gukenera guterwa inshinge kenshi, mu gihe abandi bazikenera kenshi kugira ngo bagumane iyerekwa rihamye.

Muganga wawe w'amaso azakoresha ibizamini byihariye byo gushushanya no gupima iyerekwa kugira ngo amenye gahunda yawe y'ubuvuzi. Bazareba ibimenyetso byo kwegeranya amazi, ibikorwa by'imitsi y'amaraso, n'impinduka mu iyerekwa ryawe kugira ngo bagufashe gutanga inama.

Ni Iyihe Miterere Ibyara Ingaruka Ziterwa na Ranibizumab?

Abantu benshi bafata neza inshinge za ranibizumab, ariko nk'indi miti yose, irashobora gutera ingaruka. Kumva icyo witegura bishobora kugufasha kwitegura neza no kumenya igihe wakwegera muganga wawe.

Ingaruka zisanzwe abantu benshi bahura nazo zirimo kuribwa gato mu maso, iyerekwa rihinduka ry'agateganyo, cyangwa kumva nkaho hari ikintu kiri mu jisho ryawe. Ibi mubisanzwe birushaho gukira mu munsi umwe cyangwa ibiri nyuma yo guterwa urushinge.

Dore ingaruka zikunze kugaragara ushobora kubona:

• Umutuku w'ijisho w'igihe gito cyangwa kuribwa
• Urubavu ruto rw'ijisho cyangwa kutumva neza
• Kureba nabi mu masaha make
• Kongera umubare w'amarira
• Kumva umuvumo mu jisho ryawe
• Utudomo duto cyangwa "tuzerera" mu ireba ryawe

Ibi bikorwa bisanzwe bikunze gukemuka vuba kandi ntibisaba kuvurwa byihariye uretse amabwiriza yo kwitabwaho mugihe cyose muganga wawe atanga.

Ingaruka zitavugwa cyane ariko zikomeye zirashobora kubaho, nubwo zikora ku gice gito cy'abantu bakira ranibizumab. Izi zirimo indwara y'ijisho, gukurwaho kwa retina, cyangwa kongera umuvumo w'ijisho.

Ibikomere bidasanzwe ariko bikomeye bishobora kuba birimo:

• Indwara ikomeye y'ijisho (endophthalmitis)
• Kurabukwa cyangwa gukurwaho kwa retina
• Kongera cyane umuvumo w'ijisho
• Gutakaza cyane ireba
• Umutima cyangwa umutima (ntibivugwa cyane)

Nubwo izi ngaruka zikomeye zitavugwa cyane, ni ngombwa guhamagara muganga wawe ako kanya niba ufite urubavu rukomeye rw'ijisho, impinduka zidasanzwe mu ireba, cyangwa ibimenyetso by'indwara nk'umutuku wiyongereye, gushiraho, cyangwa kumva urumuri.

Ninde utagomba gufata Ranibizumab?

Ranibizumab ntabwo ikwiriye kuri buri wese, kandi muganga wawe azasuzuma neza niba ari umutekano kuri wewe. Abantu bafite indwara z'ijisho zikora ntibashobora kwakira ubu buvuzi kugeza igihe indwara ikemutse rwose.

Ntabwo ugomba kwakira ranibizumab niba ufite allergie ku muti cyangwa ibice byawo. Muganga wawe azakubaza amateka yawe ya allergie mbere yo gutangira kuvura kugirango yemeze umutekano wawe.

Abantu bafite indwara zimwe na zimwe bagomba gutekerezwa byihariye mbere yo kwakira ranibizumab. Niba ufite amateka y'umutima, umutima, cyangwa izindi ngorane za cardiovascular, muganga wawe azagereranya inyungu n'ibishobora kuba byatera.

Abagore batwite bagomba kwirinda ranibizumab keretse inyungu zishoboka zigaragaza neza ko zirenze ibyago. Niba uteganya gutwita cyangwa uri konjesha, ganira n'umuganga wawe kugira ngo umenye icyo wakora neza.

Amazina y'ubwoko bwa Ranibizumab

Ranibizumab iboneka munsi y'izina ry'ubwoko rya Lucentis, rikaba ari ryo rimenyerewe cyane ry'uyu muti. Umuganga wawe cyangwa umufarumasiti ashobora kubyita izina iryo ari ryo ryose.

Ibihugu bimwe bishobora kugira amazina y'ubwoko bwa ranibizumab, ariko Lucentis iracyari izina ry'ubwoko ry'ibanze ku isi hose. Uyu muti ni umwe uko byagenda kose izina ry'ubwoko rikoreshwa.

Igihe uvugana n'abaganga ku bijyanye n'imiti yawe, urashobora gukoresha "ranibizumab" cyangwa "Lucentis" - bazasobanukirwa ko uvuga umuti umwe.

Izindi miti isimbura Ranibizumab

Imiti myinshi ishobora kuvura indwara z'amaso zisa niba ranibizumab itagukwiriye. Iyi miti isimbura ikora mu buryo busa ariko ishobora kugira gahunda zitandukanye zo kuyikoresha cyangwa ingaruka zitandukanye.

Bevacizumab (Avastin) ni indi miti yica VEGF abaganga rimwe na rimwe bakoresha ku buryo butemewe n'amategeko ku ndwara z'amaso. Ifite imiterere isa na ranibizumab ariko yabanje gukorwa kugira ngo ivure kanseri.

Aflibercept (Eylea) ni indi nzira ikinga VEGF na poroteyine zifitanye isano. Abantu bamwe bashobora gusubiza neza kuri uyu muti cyangwa bagomba guterwa inshinge kenshi kurusha uko byaba bimeze kuri ranibizumab.

Umuganga wawe w'amaso azatekereza ibintu nk'indwara yawe yihariye, amateka yawe y'ubuvuzi, n'ubwishingizi igihe agushakira umuti mwiza.

Ese Ranibizumab iruta Bevacizumab?

Ranibizumab na bevacizumab ni imiti ikora neza ku ndwara z'amaso zisa, kandi ubushakashatsi bwerekana ko bikora neza ku bantu benshi. Guhitamo hagati yabo akenshi biterwa n'ibintu bifatika kurusha itandukaniro rikomeye mu mikorere.

Ranibizumab yateguwe byihariye kandi igeragezwa ku ndwara z'amaso, mu gihe bevacizumab yabanje gukorerwa kuvura kanseri. Ariko, imiti yombi ifite amateka maremare y'umutekano iyo ikoreshwa mu jisho.

Ubushakashatsi bumwe buvuga ko ranibizumab ishobora kugira ibyago bike byo kugira ingaruka zimwe na zimwe, ariko itandukaniro muri rusange ni rito. Muganga wawe azatekereza ku miterere yawe bwite, harimo amateka yawe y'ubuvuzi n'ubwishingizi, mugihe atanga inama.

Ikintu cy'ingenzi ni ukubona uburyo bwo kuvura bukora neza kuri wewe kandi bujyanye n'imibereho yawe n'ibyo ukeneye mu buvuzi. Imiti yombi yafashije abantu babarirwa muri za miliyoni kubungabunga neza icyerekezo cyabo.

Ibikunze Kubazwa Kuri Ranibizumab

Ese Ranibizumab irakwiriye abantu barwaye diyabete?

Yego, ranibizumab ikunze kwandikirwa abantu barwaye diyabete, cyane cyane abafite edema ya macula ya diyabete cyangwa retinopathy ya diyabete. Mubyukuri, ibibazo by'amaso bifitanye isano na diyabete biri mubintu bisanzwe bituma abaganga bandika uyu muti.

Muganga wawe azagenzura imiyoborere yawe ya diyabete hamwe n'imiti y'amaso yawe. Kugenzura neza isukari mu maraso birashobora gufasha ranibizumab gukora neza kandi bishobora kugabanya inshuro y'inkingo zikenewe uko igihe kigenda.

Nigute nzakora niba nifashishije cyane ranibizumab?

Ntushobora gukoresha cyane ranibizumab kuko itangwa gusa nabaganga bafite imyitozo mumashuri ya kaminuza. Urutonde rurapimwa neza kandi rugatangwa numuganga wawe w'amaso.

Niba ufite impungenge kubijyanye n'urukingo rwawe cyangwa ukagira ibimenyetso bidasanzwe nyuma yo kuvurwa, vugana numuganga wawe w'amaso ako kanya. Barashobora gusuzuma niba ibimenyetso byawe bifitanye isano numuti cyangwa ikindi kibazo.

Nigute nzakora niba ntasize urukingo rwa ranibizumab?

Niba warasibye urukingo rwa ranibizumab rwari rwateganyijwe, vugana na muganga wawe w'amaso vuba bishoboka kugira ngo musubizeho gahunda. Ntuzategereze kugeza igihe cyo gusuzumwa gisanzwe, kuko gutinda mu kuvurwa bishobora kugira ingaruka ku mikorere y'amaso yawe.

Muganga wawe azagena igihe cyiza cyo gukora urukingo rwawe rushingiye ku gihe cyashize utaravurwa n'uko amaso yawe ameze ubu. Bashobora gukenera gusuzuma ijisho ryawe mbere yo gukomeza urukingo.

Ni ryari nshobora kureka gufata ranibizumab?

Icyemezo cyo kureka ranibizumab kigomba gufatwa na muganga wawe w'amaso rushingiye ku buryo ijisho ryawe ryitwara mu kuvurwa n'intego rusange zo kureba. Abantu bamwe bashobora guhagarika kuvurwa, mu gihe abandi bakeneye inkingo zikomeza kugira ngo bagumane ubushobozi bwabo bwo kureba.

Muganga wawe azakoresha ibizamini by'amaso bisanzwe n'ibizamini by'amashusho kugira ngo akurikirane uko ubuzima bwawe buhagaze. Niba ijisho ryawe rigumye rimeze neza nta mazi cyangwa imitsi y'amaraso ikura, bashobora kugusaba kongera igihe hagati y'inkingo cyangwa guhagarika kuvurwa.

Nshobora gutwara imodoka nyuma yo guterwa urukingo rwa ranibizumab?

Abaganga benshi basaba gutegura uburyo bwo gutwara abantu nyuma yo guterwa urukingo rwa ranibizumab, kuko ubushobozi bwawe bwo kureba bushobora guhuma by'agateganyo cyangwa ushobora kumva utameze neza. Iyi ngamba ifasha kurengera umutekano wawe n'umutekano w'abandi bari mu muhanda.

Ubusanzwe ubushobozi bwawe bwo kureba busubira uko bwari bumeze mbere mu masaha make nyuma yo guterwa urukingo, ariko biruta kwitonda. Kugira umuntu ukutwara bituma uruhura amaso yawe mu rugendo rwo gutaha, ibyo bishobora kugufasha kumva umeze neza no gukira.