Ravulizumab-cwvz (inzira y'umutima)
Amoko ahari
Ultomiris
Ibyerekeye uyu muti
Injeksiyon ya Ravulizumab-cwvz ikoreshwa mu kuvura indwara y'amaraso yitwa paroxysmal nocturnal hemoglobinuria (PNH). Iyi miti ifasha kugabanya kurimbuka cyangwa kwangirika kw'uturemangingo tw'amaraso atukura (hemolysis) mu barwayi bafite PNH. Injeksiyon ya Ravulizumab-cwvz kandi ikoreshwa mu kuvura atypical hemolytic uremic syndrome (aHUS) mu bakuru n'abana. Injeksiyon ya Ravulizumab-cwvz kandi ikoreshwa mu kuvura ikibazo cy'imitsi n'imikaya yitwa generalized myasthenia gravis (gMG) mu barwayi bafite anti-acetylcholine receptor (AChR) antibody. Injeksiyon ya Ravulizumab-cwvz kandi ikoreshwa mu kuvura neuromyelitis optica spectrum disorder (NMOSD), indwara idakunze kugaragara itera kubyimba kw'imitsi y'amaso n'umugongo. Ikoreshwa mu barwayi bafite anti-aquaporin-4 (AQP4) antibody. Injeksiyon ya Ravulizumab-cwvz ni imiti igizwe n'antikorps imwe gusa ikora ku mikorere y'umubiri. Iyi miti iboneka gusa muri gahunda y'ikwirakwizwa rigenzurwa yitwa Ultomiris® REMS (Risk Evaluation and Mitigation Strategy) Program. Iyi miti iboneka mu buryo bukurikira:
Mbere yo gukoresha uyu muti
Mu gihe cyemezo cyo gukoresha imiti, ibyago byo gufata imiti bigomba kupimirwa ugereranyije n'akamaro izagira. Iki ni cyemezo uzatanga hamwe na muganga wawe. Kuri iyi miti, ibi bikurikira bigomba kwitabwaho: Bwira muganga wawe niba wigeze ugira uburwayi butasanzwe cyangwa ubwo kwangirika kw'umubiri kuri iyi miti cyangwa izindi miti. Nanone, bwira umuhanga mu by'ubuzima ufite andi moko y'uburwayi, nko ku biribwa, amabara, ibintu byongera ubuzima, cyangwa inyamaswa. Ku bicuruzwa bitagomba kwandikwa, soma neza ibikoresho biri ku gipfunyika cyangwa ku kimenyetso. Ubushakashatsi bukwiye bwakozwe kugeza ubu ntabwo bwagaragaje ibibazo byihariye by'abana byabuza ikoreshwa ry'urushinge rwa ravulizumab-cwvz mu kuvura indwara ya paroxysmal nocturnal hemoglobinuria (PNH) na atypical hemolytic uremic syndrome (aHUS) mu bana bafite ukwezi kumwe cyangwa barengeje. Ariko kandi, umutekano n'ingaruka nziza ntibyaragaragajwe mu kuvura PNH na aHUS mu bana bari munsi y'ukwezi kumwe, cyangwa mu kuvura indwara ya generalized myasthenia gravis (gMG) na neuromyelitis optica spectrum disorder (NMOSD) mu bana. Ubushakashatsi bukwiye bwakozwe kugeza ubu ntabwo bwagaragaje ibibazo byihariye by'abakuze byabuza ikoreshwa ry'urushinge rwa ravulizumab-cwvz mu bakuze. Nta bushakashatsi buhagije ku bagore bwo kumenya ibyago by'uruhinja mu gihe bakoresha iyi miti mu gihe cyo konsa. Pima inyungu zishoboka ugereranyije n'ibyago bishoboka mbere yo gufata iyi miti mu gihe cyo konsa. Nubwo imiti imwe n'imwe idakwiye gukoreshwa hamwe na gato, mu bindi bihe imiti ibiri itandukanye ishobora gukoreshwa hamwe nubwo hariho ikibazo gishobora kubaho. Muri uru rubanza, muganga wawe ashobora kwifuza guhindura umwanya, cyangwa izindi ngamba zishobora kuba ngombwa. Iyo ufashe iyi miti, ni ingenzi cyane ko umuhanga mu by'ubuzima azi niba ufashe imiti iri hasi. Ibi bikurikira byatoranijwe hashingiwe ku kamaro kabyo kandi si ngombwa ko ari byose. Gukoresha iyi miti hamwe n'imiti ikurikira ntibisanzwe bisabwa, ariko bishobora kuba ngombwa mubihe bimwe na bimwe. Niba imiti yombi yandikiwe hamwe, muganga wawe ashobora guhindura umwanya cyangwa uko uyikoresha rimwe cyangwa uko uyikoresha yombi. Imiti imwe n'imwe ntikwiye gukoreshwa mu gihe cyo kurya cyangwa hafi yacyo cyangwa kurya imirire imwe n'imwe kuko hariho ikibazo gishobora kubaho. Gukoresha inzoga cyangwa itabi hamwe n'imiti imwe n'imwe bishobora kandi gutera ikibazo. Ganira n'umuhanga mu by'ubuzima ku gukoresha imiti yawe hamwe n'ibiribwa, inzoga, cyangwa itabi. Kuba hari ibindi bibazo by'ubuzima bishobora kugira ingaruka ku ikoreshwa ry'iyi miti. Menya neza kubwira muganga wawe niba ufite ibindi bibazo by'ubuzima, cyane cyane:
Uburyo bwo gukoresha uyu muti
Umuforomokazi cyangwa undi wubatse ubumenyi mu buvuzi azaguha wowe cyangwa umwana wawe iki kiyiko mu bitaro. Gitangwa hakoreshejwe urushinge rw'imiti rwashyizwe mu mubiri wawe. Iki kiyiko kigomba gutangwa buhoro buhoro. Urusinge ruzasigara aho rugashyizwe mu gihe kitarenze isaha imwe. Mu bindi bihe, urushinge rushobora gukenera kuguma aho rugashyizwe mu gihe kigera ku masaha 4. Muganga wawe azakukurikirana byibuze isaha imwe nyuma yo gutanga imiti kugira ngo arebe niba hari ingaruka zitari nziza. Ni ngombwa cyane ko wumva ibisabwa muri gahunda ya Ultomiris® REMS, kandi ugahabwa amabwiriza y'imiti ya Ultomiris® n'amabwiriza ku barwayi. Soma kandi ukurebereho aya mabwiriza neza. Baza muganga wawe niba ufite ikibazo icyo ari cyo cyose. Baza umucuruzi w'imiti amabwiriza y'imiti niba utayifite. Niba uri guhindura uburyo bwo kuvurwa ukuva kuri Soliris® ujya kuri Ultomiris®, ugomba guhabwa umwanya wa mbere wa Ultomiris® mu gihe cy'imiti ya Soliris® uteganyijwe. Hamagara muganga wawe cyangwa umucuruzi w'imiti kugira ngo aguhe amabwiriza.
Umuhakana: Kanama ni urubuga rw'amakuru y'ubuzima kandi ibisubizo byayo ntibigize inama z'ubuvuzi. Jya ubona umuganga ufite uruhushya rwo gukorera hafi yawe mbere yo gukora impinduka izo ari zo zose.