Icyo Revefenacin ari cyo: Ibyo ikoreshwa, Uburyo bwo kuyifata, Ingaruka zayo n'ibindi

Revefenacin ni umuti wandikirwa na muganga ufasha abantu barwaye indwara y'umutima ituma umuntu ahumeka nabi (COPD) guhumeka neza. Ni umuti wita ku miyoboro y'ubuhumekero ukora utuma imitsi ikikije imiyoboro yawe y'ubuhumekero iruhuka, bigatuma umwuka winjira no gusohoka mu muhaha wawe byoroha.

Uyu muti uza mu buryo bw'umuti usukwa mu byuma by'ubuhumekero. Muganga wawe ashobora kukwandikira revefenacin niba urwaye COPD kandi ukeneye kuvurwa buri munsi kugira ngo ucunge ibimenyetso byo guhumeka kwawe kandi ugabanye ibibazo byiyongera.

Revefenacin ni iki?

Revefenacin ni mu cyiciro cy'imiti yitwa long-acting muscarinic antagonists (LAMAs). Bitekereze nk'urufunguzo rufungura imiyoboro y'ubuhumekero yifunze mu muhaha wawe, rukayifungura igihe kirekire kugira ngo ushobore guhumeka neza.

Uyu muti wagenewe abantu barwaye COPD, indwara irimo bronchitis idakira na emphysema. Bitandukanye n'imiti yihutisha guhumeka ikora vuba mu gihe cy'ibibazo byo guhumeka, revefenacin ni umuti ukoreshwa buri munsi kugira ngo wirinde ibibazo byo guhumeka mbere y'uko bitangira.

Uyu muti ni mushya, wemejwe na FDA mu 2018. Ugenewe gukoreshwa rimwe ku munsi, bishobora koroshya gukurikiza gahunda yawe yo kuvurwa ugereranije n'imiti ikeneye gufatwa inshuro nyinshi ku munsi.

Revefenacin ikoreshwa mu iki?

Revefenacin ikoreshwa by'umwihariko mu kuvura indwara y'umutima ituma umuntu ahumeka nabi (COPD) ku bantu bakuru. Ifasha gucunga ibimenyetso bya buri munsi bya COPD kandi igabanya inshuro z'ibibazo bishobora kukujyana mu bitaro.

Muganga wawe ashobora kukwandikira uyu muti niba ufite COPD yo hagati cyangwa ikomeye kandi ukagira ingorane zo guhumeka buri gihe. Bifasha cyane niba wumva uhumeka nabi mu bikorwa bya buri munsi nk'ukugenda, kuzamuka amategeko, cyangwa no kwambara.

Uyu muti ukora neza cyane nk'igice cy'uburyo bwo kuvura indwara ya COPD. Ibi bishobora kuba bikubiyemo indi miti, imyitozo yo guhumeka, impinduka mu mibereho, no kugenzura buri gihe n'ikipe yawe y'ubuvuzi.

Revefenacin ikora ite?

Revefenacin ikora ibuza imitsi yihariye mu myanya yawe yo guhumeka yitwa imitsi ya muscarinic. Iyo iyi mitsi yabujijwe, imitsi ikikije imyanya yawe yo guhumeka iraruhuka kandi ikaguma iruhutse mu masaha nka 24.

Ibi bifatwa nk'umuti ukomeye mu buryo bwo kuvura indwara ya COPD. Ntabwo ikora vuba nka inhalers yo gutabara, ariko itanga ubufasha buhoraho, burambye bufasha kwirinda ibibazo byo guhumeka umunsi wose.

Uyu muti utangira gukora mu masaha make nyuma yo gufata urugero rwa mbere, ariko ushobora kutumva ibyiza byose mu minsi mike cyangwa mu byumweru. Imyanya yawe yo guhumeka buhoro buhoro iragabanuka kandi irafunguka cyane uko ukomeza gukoresha umuti buri gihe.

Nkwiriye gufata Revefenacin nte?

Ukwiriye gufata revefenacin nk'uko muganga wawe abikwandikiye, akenshi rimwe ku munsi ukoresheje imashini ya nebulizer. Uyu muti uza mu tubindi duto turimo urugero rwa mbere rw'umuti w'amazi.

Uku niko wakoresha revefenacin neza:

1. Komesha intoki zawe neza mbere yo gukoresha umuti
2. Kura agacupa kamwe mu gakapu ka foil mbere yo gukoresha
3. Suka ibirimo byose mu gikombe cyawe cya nebulizer
4. Huza nebulizer na compressor yawe hanyuma uhumeke bisanzwe unyuze mu kanwa
5. Komeza kugeza igihe umuti wose ushize (muri rusange iminota 8-15)

Ushobora gufata uyu muti ufite cyangwa udafite ibiryo, kandi ntugomba kwirinda kurya mbere cyangwa nyuma yo gufata urugero. Igihe kigukwiriye ni cyiza, ariko gerageza kuwufata ku gihe kimwe buri munsi kugirango ugumane urwego ruzigama mu mubiri wawe.

Sukuza ibikoresho byawe bya nebulizer nyuma yo kubikoresha uko bikurikira amabwiriza y'umukora. Ibi birinda ko bagiteri zikwira kandi bituma imiti ikora neza.

Nzakoresha Revefenacin igihe kingana iki?

Revefenacin akenshi ni umuti ukoreshwa igihe kirekire uzakenera gufata buri munsi igihe cyose muganga wawe abikugiraho inama. Abantu benshi bafite COPD bakeneye gukoresha imiti nk'iyi buri gihe kugirango bagumane ibimenyetso byabo bikontorolwa.

Muganga wawe azagenzura uko umuti ukora neza kuri wowe binyuze mu kugenzura buri gihe no gupima imikorere y'ibihaha. Niba guhumeka kwawe kuzamuka cyane cyangwa niba ugize ingaruka ziterwa n'umuti, muganga wawe ashobora guhindura gahunda yawe yo kuvurwa.

Ntuzigere uhagarika gufata revefenacin ako kanya utabanje kuvugana na muganga wawe. Ibimenyetso byawe bya COPD bishobora kugaruka cyangwa bikiyongera niba uhagaritse umuti ako kanya. Niba ukeneye guhagarika impamvu iyo ari yo yose, muganga wawe azagufasha kubikora mu buryo butekanye.

Ni izihe ngaruka ziterwa na Revefenacin?

Abantu benshi bafata revefenacin neza, ariko nk'imiti yose, ishobora gutera ingaruka. Inkuru nziza ni uko ingaruka zikomeye zitaba kenshi, kandi abantu benshi bagira ibimenyetso byoroheje gusa bikagenda neza uko umubiri wabo wimenyereza umuti.

Ingaruka zisanzwe ushobora kugira zirimo:

• Inkorora (ishobora kugaragara nk'aho bitumvikana ku muti wo guhumeka)
• Uburwayi bwo mu nzira yo hejuru yo guhumeka nk'ibicurane
• Umutwe
• Urubavu rwo mu mugongo
• Kuguma mu nda

Ibi bimenyetso akenshi biba byoroheje kandi by'igihe gito. Niba bikomeje cyangwa bikaba bibangamiye, ganira na muganga wawe kubyerekeye uburyo bwo kubicunga.

Ingaruka zikomeye ntizikunda kubaho ariko zisaba ubufasha bwihutirwa bwa muganga. Vugana na muganga wawe ako kanya niba ugize ikibazo cyo kunyara, kuribwa kw'amaso cyangwa guhinduka kw'ubureba, ibimenyetso bikomeye byo kwivumbura ku miti, cyangwa ibibazo byo guhumeka bikiyongera nyuma yo gukoresha umuti.

Abantu bamwe bashobora guhura n'ingaruka zidasanzwe aho guhumeka kwabo kurushaho kuba bibi nyuma yo gukoresha umuti. Ibi ntibisanzwe ariko birakomeye - reka gukoresha revefenacin ako kanya kandi uvugishe muganga wawe niba ibi bibaye.

Ninde Utagomba Gukoresha Revefenacin?

Revefenacin ntabwo ikwiriye buri wese. Ntugomba gukoresha uyu muti niba ufite allergie kuri revefenacin cyangwa ibindi bikoresho byayo, cyangwa niba ufite asima nk'ikibazo cyawe cy'ibanze cyo guhumeka.

Muganga wawe azakenera kumenya ibindi bibazo by'ubuzima mbere yo gutanga revefenacin. Wibuke cyane cyane kuvuga niba ufite:

• Glaucoma ifunganye
• Urugano rwagutse cyangwa kugorana kwihagarika
• Ibibazo by'impyiko
• Uburwayi bw'umutima butunganye
• Uburwayi bwo gufatwa n'indwara

Ibi bibazo ntibisobanura ko udashobora gukoresha revefenacin, ariko muganga wawe ashobora gukenera kugukurikiranira hafi cyangwa guhindura gahunda yawe yo kuvura.

Niba utwite, uteganya gutwita, cyangwa wonka, biganireho na muganga wawe. Hariho amakuru make yerekeye umutekano wa revefenacin mugihe cyo gutwita, bityo muganga wawe azagereranya inyungu n'ibishobora kuba byateza akaga.

Izina ry'ubwoko bwa Revefenacin

Revefenacin igurishwa ku izina ry'ubwoko bwa Yupelri. Ubu nicyo gusa izina ry'ubwoko ririho kuri uyu muti muri Leta Zunze Ubumwe z'Amerika.

Yupelri iza mu ducupa dukoreshwa rimwe rukoreshwa turimo mikrogramu 175 za revefenacin muri solusiyo ya 3 mL. Buri gicupa cyagenewe gukoreshwa rimwe kandi kigomba kujugunywa nyuma yo gufungura, niyo utakoresheje imiti yose.

Umuti ukorwa na Mylan Pharmaceuticals kandi uboneka gusa ku mpapuro zanditswe na muganga. Nta verisiyo rusange iraboneka, kuko umuti ukiri mushya.

Uburyo bwo gusimbuza Revefenacin

Niba revefenacin itagukwiriye, hari izindi miti myinshi ya COPD ikora mu buryo busa. Muganga wawe ashobora gutekereza ku bindi byongera imitsi y'umubiri (LAMAs) nk'urugero rwa tiotropium (Spiriva) cyangwa umeclidinium (Incruse Ellipta).

Abantu bamwe barushaho kumera neza bakoresheje imiti ivanze irimo LAMA na beta-agonist ikora igihe kirekire (LABA). Izi mvange, nk'urugero rwa umeclidinium/vilanterol (Anoro Ellipta) cyangwa glycopyrrolate/formoterol (Bevespi Aerosphere), zishobora gutanga uburyo bwuzuye bwo kugenzura ibimenyetso.

Muganga wawe ashobora kandi gutekereza ku mvange ya gatatu irimo steroid ihumeka hamwe na LAMA na LABA. Guhitamo biterwa n'ibimenyetso byawe byihariye, uko COPD yawe ikaze, n'uko witwara neza ku miti itandukanye.

Imiti yose ifite inyungu zayo n'ingaruka zishobora kubaho. Muganga wawe azagufasha kubona uburyo bwo kuvura bukora neza ku miterere yawe yihariye.

Ese Revefenacin iruta Tiotropium?

Byombi revefenacin na tiotropium ni imiti ya COPD ikora neza kandi ikomoka mu cyiciro kimwe cy'imiti (LAMAs). Zikora mu buryo busa ariko zifite itandukaniro rikomeye rishobora gutuma imwe ikwemerera kurusha iyindi.

Revefenacin ifatwa rimwe ku munsi hakoreshejwe nebulizer, mugihe tiotropium isanzwe ifatwa rimwe ku munsi hakoreshejwe inhaler y'ifu yumye (nubwo hariho na verisiyo ya nebulizer). Niba ugira ingorane zo gukoresha inhalers cyangwa ukunda kuvurwa na nebulizer, revefenacin irashobora kukworohera.

Imiti yombi ifite imikorere isa mu kunoza imikorere y'ibihaha no kugabanya ibibazo bya COPD. Guhitamo hagati yabyo akenshi biterwa n'icyo ukunda, ubushobozi bwawe bwo gukoresha ibikoresho bitandukanye, n'uko wihanganira imiti yose.

Muganga wawe azatekereza ibyo ukeneye byihariye, imiti indi urimo gufata, n'ubuzima bwawe muri rusange igihe afata icyemezo cy'umuti ukugirira neza. Abantu bamwe babona umuti umwe ubafitiye akamaro kurusha undi, kandi ni ibisanzwe rwose kugerageza uburyo butandukanye kugira ngo umenye icyo gikora neza.

Ibibazo Bikunze Kubazwa Kuri Revefenacin

Q1. Ese Revefenacin iratekanye ku ndwara z'umutima?

Revefenacin muri rusange irashobora gukoreshwa neza n'abantu barwaye indwara z'umutima, ariko muganga wawe azagomba kugukurikiranira hafi. Uyu muti rimwe na rimwe ushobora gutera impinduka mu mutima, nubwo ibi bitaba kenshi.

Niba urwaye indwara z'umutima, menyesha muganga wawe imiti yose ufata y'umutima mbere yo gutangira gufata revefenacin. Ashobora gushaka kureba umuvuduko w'umutima wawe kenshi cyangwa agahindura gahunda yawe yo kuvurwa kugira ngo yemeze umutekano wawe.

Q2. Nkwiriye gukora iki niba nifashishije revefenacin nyinshi bitunguranye?

Niba witunguye ugakoresha revefenacin irenze urugero rwanditswe, ntugahagarike umutima. Vugana na muganga wawe cyangwa ikigo gishinzwe kugenzura uburozi ako kanya kugira ngo baguhe ubuyobozi bw'icyo gukora gikurikira.

Ibimenyetso byo kurenza urugero bishobora kuba umunwa wumye cyane, kugorwa no kunyara, amaso atabona neza, cyangwa umutima utera cyane. Niba ubonye kimwe muri ibi bimenyetso, gisha ubufasha bw'ubuvuzi ako kanya. Kurenza urugero kwabayeho bitunguranye ntibikunda gutera ibibazo bikomeye, ariko buri gihe ni byiza kwirinda.

Q3. Nkwiriye gukora iki niba nciweho urugero rwa revefenacin?

Niba ucikwa urugero rwa revefenacin, rufate ako kanya wibukire kuri uwo munsi. Niba igihe cyo gufata urugero rukurikira kigeze, reka urugero waciweho ukomeze gahunda yawe isanzwe.

Ntuzigere ufata urugero ebyiri icyarimwe kugira ngo usimbure urugero waciweho. Ibi bishobora kongera ibyago byo kugira ingaruka ziterwa n'umuti utagize akamaro kongerewe. Niba ukunda kwibagirwa urugero, tekereza gushyiraho alarume ya buri munsi cyangwa gukoresha porogaramu yibutsa imiti.

Q4. Nshobora kureka gufata revefenacin ryari?

Ugomba guhagarika gufata revefenacin gusa igihe muganga wawe akubwiye ko byemewe. Ibi bikunda kuba iyo ibimenyetso byawe bya COPD bigabanutse cyane, niba ubonye ingaruka zidakwiriye, cyangwa niba muganga wawe ashaka kugerageza uburyo bwo kuvura butandukanye.

COPD ni indwara ihoraho isaba kuvurwa igihe kirekire. N'iyo wumva umeze neza mugihe ufata revefenacin, guhagarika imiti bishobora gutuma ibimenyetso byawe bisubira. Buri gihe ganira ku mpungenge zose zerekeye gukomeza kuvurwa n'umuganga wawe.

Q5. Nshobora Kugenda Nifitiye Revefenacin?

Yego, urashobora kugenda ufite revefenacin, ariko uzakenera gutegura mbere. Imiti ikeneye kubikwa muri firigo kugeza igihe witeguye kuyikoresha, bityo uzakenera gutegura uburyo bwo kuyibika neza mugihe ugenda.

Kugenda mu ndege, paka imiti yawe mu gikapu cyawe cyo mu ntoki hamwe na kopi y'urwandiko rwawe rw'umuti. Urashobora gukuramo amacupa kuva muri firigo kugeza ku minsi 7, bikaba bikwiye urugendo rwinshi. Niba urugendo rwawe rurenze ibyo, uzakenera kumenya neza ububiko bwa firigo aho ujya.