Sacrosidase ni iki: Ibikoreshwa, Urutonde rw'imiti, Ingaruka ziterwa n'iyo miti n'ibindi

Sacrosidase ni umuti wandikirwa na muganga usimbura imisemburo ifasha abantu gushonga sucrose (isukari yo ku meza) iyo umubiri wabo utabasha gukora iyi misemburo ihagije. Uyu muti w'amazi urimo imisemburo imwe n'imwe umara igifu gito gikora mu buryo busanzwe kugira ngo gisenye isukari ikore ibice bito, byoroshye kwinjizwa mu mubiri.

Niba umaze igihe uhanganye n'uburibwe mu nda, kubyimba, cyangwa guhitwa nyuma yo kurya ibiryo birimo isukari, sacrosidase ishobora kuba umuti muganga wawe agutera. Yateguwe by'umwihariko ku bantu bafite uburwayi bw'inzoka bwitwa congenital sucrase-isomaltase deficiency, aho umubiri utabasha gukora neza isukari zimwe na zimwe.

Sacrosidase ikoreshwa mu iki?

Sacrosidase ivura congenital sucrase-isomaltase deficiency (CSID), uburwayi bw'inzoka aho umubiri wawe utagira imisemburo ihagije yo gushonga sucrose na starch zimwe na zimwe. Abantu bafite ubu burwayi bahura n'ibimenyetso bitari byiza byo mu gifu igihe cyose bariye ibiryo birimo isukari yo ku meza cyangwa starch zimwe na zimwe.

Ubu buvuzi busimbura imisemburo bukora butanga imisemburo yo mu gifu umubiri wawe ukeneye. Iyo ufata sacrosidase mbere yo kurya ibiryo birimo isukari, bifasha gusenya sucrose mu gihe cyo mu gifu cyawe, bikakumira ibimenyetso bibabaza byari kubaho.

Uyu muti ufasha cyane mu gucunga ibimenyetso bibaho nyuma yo kurya ibiryo nk'imbuto, ibicuruzwa byatewe, amaswiti, cyangwa ibicuruzwa byose birimo isukari yongerewe. Hatabayeho ubu bufasha bw'imisemburo, ibi biryo bishobora gutera ibibazo bikomeye byo mu gifu ku bantu bafite CSID.

Sacrosidase ikora ite?

Sacrosidase ikora isimbura imisemburo ya sucrase yaburiye cyangwa idahagije mu gihe cyo mu gifu cyawe. Uyu musemburo usanzwe wicara ku murongo w'igifu cyawe gito, aho usenya sucrose ikora glucose na fructose - isukari ebyiri zoroshye umubiri wawe ushobora kwinjiza byoroshye.

Iyo ufata sacrosidase mbere yo kurya, igenda mu mara mato yawe igakora akazi kamwe n'ako imisemburo yawe isanzwe ikora. Bitekereze nk'uko uha sisitemu yawe yo mu gifu ibikoresho bikwiye kugira ngo ifate isukari neza.

Ibi bifatwa nk'ubuvuzi bugamije kandi bwihariye aho kuba umuti ukomeye. Ntabwo bigira ingaruka ku mubiri wawe wose - bitanga gusa imikorere y'imisemburo yaburiye mu nzira yawe yo mu gifu, bigatuma ushobora gutunganya ibiryo birimo isukari mu buryo busanzwe.

Nkwiriye gufata sacrosidase nte?

Fata sacrosidase nk'uko umuganga wawe abitegeka, akenshi mbere yo kurya cyangwa gufata ibiryo birimo sucrose. Umuti w'amazi uza ufite igikoresho cyo gupima kugira ngo wemeze ko ubona urugero rukwiye buri gihe.

Uzakenera gufata uyu muti mbere y'iminota nka 15 yo kurya ibiryo birimo isukari. Urashobora kuwufata mu kanwa cyangwa ukawuvanga n'amazi make, amata, cyangwa ifu y'abana niba bikenewe. Ntukigere uwuvanga n'umutobe w'imbuto, kuko aside ishobora kugabanya imikorere y'imisemburo.

Bika umuti muri firigo yawe kandi ntuzigere uwukonjesha. Imisemburo irashobora kwangizwa n'ubushyuhe, bityo uyibike itonoye kugeza igihe witeguye kuyikoresha. Niba uri mu rugendo, urashobora kuyibika ku bushyuhe busanzwe mu gihe gito, ariko uyisubize muri firigo vuba bishoboka.

Buri gihe pima urugero rwawe neza ukoresheje igikoresho cyo gupima cyatanzwe. Ibiyiko byo mu gikoni ntibihagije mu gupima imiti, kandi kubona urugero rukwiye ni ingenzi kugira ngo imisemburo ikore neza.

Mbwiriza gufata sacrosidase igihe kingana iki?

Sacrosidase akenshi ni ubuvuzi burambye uzakenera gukomeza igihe cyose ushaka kurya ibiryo birimo sucrose. Kubera ko CSID ari indwara ya genetike, ubushobozi bw'umubiri wawe bwo gukora imisemburo yaburiye ntibuzatera imbere uko imyaka yicuma.

Abantu benshi basanga bakeneye gufata sacrosidase igihe cyose kugira ngo bacunge neza ibimenyetso byabo. Ibi ntibiterwa n'uko umuti ubatesha umutwe, ahubwo ni uko kubura kwa enzyme y'ibanze ari ibihe byose.

Muganga wawe azagenzura uko umuti ukora neza kuri wowe kandi ashobora guhindura gahunda yawe yo gufata imiti bitewe n'ibimenyetso byawe n'ibyo ukeneye mu mirire. Abantu bamwe basanga bashobora kugabanya urugero rw'imiti bafata niba bagabanya ibiryo birimo isukari, mu gihe abandi bakeneye gufata imiti buri gihe kugira ngo bagumane umunezero.

Ni Ibihe Bikorwa Bigaragara Byo Ku Ruhande Rwa Sacrosidase?

Abantu benshi bafata sacrosidase neza, ariko nk'undi muti uwo ari wo wose, ushobora gutera ibikorwa bigaragara ku ruhande ku bantu bamwe. Inkuru nziza ni uko ibikorwa bigaragara ku ruhande bikomeye bidakunze kubaho hamwe n'iyi terapi ya enzyme isimbura.

Dore ibikorwa bigaragara ku ruhande bikunze kuvugwa ushobora guhura na byo:

• Urubavu rw'inda cyangwa kutumva neza mu nda
• Urugimbu cyangwa kumva urwaye
• Impiswi, cyane cyane igihe utangiye kuvurwa
• Kuruka mu bihe bimwe
• Umutwe
• Urugero cyangwa kumva ureremba

Ibi bimenyetso akenshi biragenda neza uko umubiri wawe wimenyereza umuti, akenshi mu byumweru bya mbere byo kuvurwa. Niba bikomeje cyangwa bikiyongera, menyesha muganga wawe kugira ngo ashobore guhindura urugero rw'imiti ufata cyangwa igihe uyifata.

Abantu bamwe bashobora guhura n'ibikorwa byo kwivumbura, nubwo ibi bidakunze kubaho. Reba ibimenyetso nk'uruhu ruranga, kuribwa, kubyimba mu maso cyangwa mu muhogo, cyangwa guhumeka bigoranye. Niba ubonye kimwe muri ibi bimenyetso, reka gufata umuti kandi usabe ubufasha bw'ubuvuzi ako kanya.

Gahoro cyane, abantu bamwe bagira ibibazo bikomeye byo mu nzira yo mu gifu cyangwa bagahura no kwiyongera kw'ibimenyetso byabo by'umwimerere. Ibi bishobora kwerekana ko urugero rw'imiti rukeneye guhindurwa cyangwa ko hari ikindi kibazo cy'ibanze gikeneye kwitabwaho.

Ni Bande Batagomba Gufata Sacrosidase?

Sacrosidase ntiribereye kuri buri wese, kandi indwara zimwe na zimwe cyangwa ibihe bishobora gutuma bidatekanye ko ukoresha uyu muti. Muganga wawe azasuzuma neza amateka yawe y'ubuzima mbere yo kuwandikira.

Ntugomba gufata sacrosidase niba ufite allergie ku bintu byose bigize cyangwa niba waragize allergie ku bindi bicuruzwa bya enzyme bisa n'ibi mu bihe byashize. Abantu bafite diyabete ikomeye bashobora gukenera gukurikiranwa byihariye, kuko uyu muti ushobora kugira ingaruka ku rwego rw'isukari mu maraso.

Dore ibihe sacrosidase itabereye:

• Allergie zizwi ku ifu y'umusemburo cyangwa ibicuruzwa by'umusemburo
• Indwara ikomeye y'impyiko cyangwa umwijima
• Indwara y'amara y'ubushyamirane mu gihe gikomeye
• Kubagwa mu gifu cyangwa mu mara vuba aha
• Diyabete ikomeye ifite ubugenzuzi buke bw'isukari mu maraso

Abagore batwite kandi bonka bagomba kuganira ku byago n'inyungu na muganga wabo, kuko hari ubushakashatsi buke ku mikoreshereze ya sacrosidase muri ibi bihe. Uyu muti ushobora kuba ngombwa niba ibimenyetso bya CSID bikomeye, ariko gukurikiranwa neza ni ngombwa.

Niba ufite indwara zidakira z'igifu zirenga CSID, muganga wawe ashobora gukenera guhindura gahunda yawe y'imiti cyangwa gutanga uburyo bwo gukurikirana kugira ngo yemeze ko uyu muti ukora neza kuri wowe.

Amazina y'ubwoko bwa Sacrosidase

Sacrosidase iboneka munsi y'izina ry'ubwoko bwa Sucraid muri Leta Zunze Ubumwe z'Amerika. Iri ni ryo zina ry'ubwoko rya mbere uzahura na ryo mugihe muganga wawe akwandikiye uyu muti.

Sucraid ikorwa nk'igisubizo cyo kunywa kandi iza mu macupa afite ibikoresho byihariye byo gupima kugirango byemeze ko imiti ipimwa neza. Uyu muti ukeneye urupapuro rwanditswe na muganga kandi ntiboneka ku isoko.

Kubera ko uyu ari umuti wihariye wo kuvura indwara idasanzwe, ubu nta bwoko bwa generic buhari. Farumasi yawe ishobora gukenera kubitegeka byihariye, bityo teganiriza mbere mugihe usubiza imiti yawe.

Uburyo bwo gusimbuza Sacrosidase

Ubu, sacrosidase niyo miti yonyine yemewe na FDA yo kuvura indwara ya CSID. Ariko, hariho uburyo bwo kuvura n'ubufasha bushobora gufasha hamwe cyangwa mu mwanya w'imiti.

Uburyo bwa mbere bwo gusimbura sacrosidase ni ukugenzura cyane imirire, bikubiyemo kwirinda ibiryo birimo sucrose no kugabanya ibiryo bimwe birimo sitashi. Ubu buryo busaba gutegura neza amafunguro no gusoma amabwiriza y'ibiryo, ariko abantu benshi bafata neza ibimenyetso byabo muri ubu buryo.

Abantu bamwe babona ubufasha buke hamwe na enzymes zo mu rwunguko, nubwo izi zitagenewe CSID kandi zishobora kutagira akamaro. Probiotics zirashobora gufasha mu gushyigikira ubuzima bw'igogora muri rusange, ariko ntizisimbura enzyme ya sucrase ibura.

Gukorana n'umuhanga mu by'imirire wumva CSID birashobora kugira akamaro gakomeye mu guteza imbere gahunda z'imirire zigabanya ibimenyetso mugihe zizana imirire ikwiye. Ubu buryo akenshi bukora neza buhuriye na sacrosidase therapy.

Ese Sacrosidase iruta imirire yonyine?

Sacrosidase itanga inyungu zikomeye kuruta imirire yonyine, cyane cyane mu bijyanye n'ubuzima bwiza n'ubushobozi bwo kurya ibintu bitandukanye. Mugihe kugenzura cyane imirire bishobora gufata ibimenyetso bya CSID, akenshi bisaba gukuraho ibiryo byinshi abantu benshi bakunda buri gihe.

Hamwe na sacrosidase, urashobora kurya imirire itandukanye irimo imbuto, ibicuruzwa byatekeshejwe, n'ibindi biryo birimo sucrose utagize ibimenyetso bikomeye byo mu igogora. Ubu bushobozi burashobora kuba bw'ingenzi cyane cyane ku iterambere ry'abana mu mibanire n'abandi n'uburyo abantu bakuru bakunda kubaho.

Ariko, imirire yonyine ikora neza kubantu bamwe, cyane cyane abashaka kutanywa imiti cyangwa bafite ibimenyetso byoroheje cyane. Guhitamo akenshi biterwa n'uburemere bw'ibimenyetso byawe, uburyo ukunda kubaho, n'uburyo imirire idafite isukari ikumvikana kuri wewe.

Abantu benshi basanga guhuza uburyo bwombi ari bwo bukora neza - gukoresha sacrosidase iyo bariye ibiryo birimo isukari nyinshi mu gihe bagitekereza ku kigero cy'isukari barya muri rusange. Ubu buryo buringaniye bushobora gutanga imiti ivura ibimenyetso mu gihe bagifite ubuzima bwiza bwo mu gifu.

Ibibazo Bikunze Kubazwa Kuri Sacrosidase

Ese Sacrosidase irakwiriye abarwayi ba diyabete?

Sacrosidase irashobora gukoreshwa n'abantu barwaye diyabete, ariko bisaba gukurikiranwa neza no guhuza n'ikipe yawe yita ku diyabete. Uyu muti ufasha gusenya sucrose ikavamo glucose na fructose, bishobora kugira ingaruka ku kigero cy'isukari mu maraso yawe.

Kubera ko sacrosidase ituma ushobora gukora neza ibiryo birimo isukari, birashoboka ko ugomba guhindura imiti yawe ya diyabete cyangwa doze ya insuline. Kora cyane n'umuganga wawe kugira ngo ukurikirane urugero rw'isukari mu maraso yawe igihe utangiye kuvurwa na sacrosidase.

Abantu benshi barwaye CSID na diyabete bakoresha sacrosidase neza mu gihe bagifite ubugenzuzi bwiza bw'isukari mu maraso. Ikintu cy'ingenzi ni ugukurikiranwa neza kandi birashoboka ko uhindura gahunda yawe yo gucunga diyabete kugira ngo wite ku kunywa isukari neza.

Nkwiriye gukora iki niba nanyoye sacrosidase nyinshi bitunguranye?

Niba unyoye sacrosidase nyinshi kuruta uko byategetswe, ntugahagarike. Kwiyongera kwa enzyme ntibitera ibibazo bikomeye, ariko ushobora guhura n'ibimenyetso byiyongereye byo mu gifu nk'inda ibabaza cyangwa impiswi.

Vugana n'umuganga wawe cyangwa umufarimasi kugira ngo ubabwire iby'iyo doze yiyongereye kandi ubabashe kubasaba inama. Bashobora kukugira inama y'icyo ugomba kwitaho niba ukeneye ubufasha bw'ubuvuzi. Bika urupapuro rw'umuti hafi kugira ngo ushobore gutanga amakuru yihariye yerekeye urugero wanyoye.

Ku bindi bice, garuka ku rugero rwawe rusanzwe rwanditswe kandi n'igihe. Ntugagerageze kureka doze kugira ngo

Niba wibagiwe gufata urugero rwa sacrosidase mbere yo kurya, uracyashobora kurufata niba wibukije mu minota 30 nyuma yo kurya. Nyuma yaho, ibiryo bizaba byaranyuze kure mu nzira yawe yo mu gifu ku buryo urwo rugero rutazagira akamaro.

Ntugafate urugero rurenzeho kugira ngo usimbure urwo wibagiwe. Ahubwo, komeza gukurikiza gahunda yawe isanzwe yo gufata imiti ku ifunguro ryawe rikuriho cyangwa ku ifunguro rito. Ushobora guhura n'ibibazo byo mu gifu bitewe n'iryo funguro, ariko ibi ni iby'igihe gito.

Tekereza gushyiraho ibyibutso kuri terefone cyangwa kubika imiti yawe ahantu hagaragara hafi yaho urira kugira ngo bigufashe kwibuka gufata imiti mbere yo kurya. Gukomeza bifasha kugenzura neza ibimenyetso.

Ni ryari nshobora kureka gufata sacrosidase?

Ushobora kureka gufata sacrosidase igihe cyose ubishakiye, ariko ibimenyetso byawe bya CSID birashoboka ko bizagaruka iyo urya ibiryo birimo sucrose. Kubera ko iyi ari indwara ya genetike, umubiri wawe ntuzatangira gukora urwo rugero rwatanzwe ku giti cyawo.

Abantu bamwe bahitamo kureka sacrosidase niba bishimiye gukurikiza imirire ikarishye ya sucrose. Abandi bafata akaruhuko ku miti mu gihe barimo kurya isukari nkeya cyane, hanyuma bakongera kuyifata igihe imirire yabo iba itandukanye.

Ganira na muganga wawe mbere yo kureka sacrosidase, cyane cyane niba utekereza gukoresha imirire mu kuyivura. Bashobora kugufasha gukora gahunda izagufasha kugira ubuzima bwiza no guhaza ibyo ukeneye mu mirire mu gihe ugenzura neza ibimenyetso byawe bya CSID.

Ese abana bashobora gufata sacrosidase?

Yego, sacrosidase ni nziza kandi ifitiye akamaro abana barwaye CSID, kandi kuvurwa hakiri kare bishobora kunoza cyane imibereho yabo n'imikurire yabo. Abana benshi barwaye CSID bahura n'ingorane zo kurya kandi bashobora kunanirwa kongera ibiro byabo neza bitewe n'ibimenyetso byo mu gifu.

Gufata imiti ku bana bishingiye ku gipimo cy'umubiri, kandi muganga w'umwana wawe azabara umubare ukwiye w'ubunini bwabo. Uwo muti ushobora kuvangwa n'amata make cyangwa ifu y'abana bato, bikoroha kuyitanga.

Abana bakunze kwitabira neza imiti ya sacrosidase, bakagaragaza irushaho kurya, kongera ibiro, no kugabanya ibibazo byo mu gifu. Ibi bishobora kuba by'ingenzi cyane ku bana biga mu mashuri bifuza kwitabira ibikorwa byo kurya mu ruhame batagira ibibazo.