Icyo Saxagliptin na Metformin ari cyo: Ibikoreshwa, Urutonde rw'imiti, Ingaruka ziterwa n'iyo miti n'ibindi

Saxagliptin na metformin ni umuti uvura indwara zifitanye isano, ufasha mu kuvura diyabete yo mu bwoko bwa 2 ukora mu buryo bubiri butandukanye kugira ngo ugenzure urugero rw'isukari mu maraso. Uyu muti wandikirwa na muganga uvura diyabete ukoresha imiti ibiri yemejwe mu gapiriso kamwe koroshya, bigufasha gukurikiza gahunda yawe yo kuvurwa.

Niba warandikiwe uyu muti, birashoboka ko wibaza uko ukora n'icyo witegura. Reka tunyuremo ibyo byose ukeneye kumenya kuri uyu muti uvura diyabete mu buryo bworoshye kandi busobanutse.

Saxagliptin na Metformin ni iki?

Saxagliptin na metformin ni umuti wandikirwa na muganga urimo ibintu bibiri bikora byose hamwe kugira ngo bifashe mu kugenzura isukari mu maraso ku bantu barwaye diyabete yo mu bwoko bwa 2. Tekereza nk'uburyo bwo gufatanya aho buri muti ukora ku isukari yo mu maraso mu buryo butandukanye.

Saxagliptin ni uwo mu itsinda ry'imiti yitwa DPP-4 inhibitors, ifasha umubiri wawe gukora insulin nyinshi iyo isukari yo mu maraso yawe iri hejuru. Metformin iva mu itsinda ryitwa biguanides, kandi ifasha kugabanya urugero rw'isukari umwijima wawe ukora mugihe kandi ifasha umubiri wawe gukoresha insulin neza.

Uyu muti uvura indwara zifitanye isano uboneka mu gapiriso ufata unywa, akenshi kabiri ku munsi hamwe n'amafunguro. Muganga wawe arabikwandikira iyo imiti imwe idatanga urugero rwo kugenzura isukari mu maraso ku giti cyayo.

Saxagliptin na Metformin bikoreshwa kubera iki?

Uyu muti wagenewe by'umwihariko kuvura diyabete yo mu bwoko bwa 2 ku bantu bakuru iyo imirire n'imyitozo ngororamubiri byonyine bidahagije kugenzura urugero rw'isukari mu maraso. Bifasha cyane cyane abantu bakeneye ubwoko burenze bumwe bw'umuti uvura diyabete kugira ngo bagere ku ntego zabo z'isukari mu maraso.

Muganga wawe ashobora kugutegeka gufata uru ruhererekane rw'imiti niba umaze igihe ufata metformin wenyine ariko uracyagira isukari nyinshi mu maraso. Ikoreshwa kandi iyo ukeneye imiti yombi ariko ukaba ushaka koroherezwa no gufata urupapuro rumwe aho gufata tubiri dutandukanye.

Umuti ukora neza nk'igice cy'umugambi wo kuvura diyabete urimo kurya neza, gukora imyitozo ngororamubiri buri gihe, no kugenzura ibiro iyo bikwiye. Ntabwo bigamije gusimbura ubu buryo bw'ubuzima bw'ingenzi ahubwo ni ukubufatanya.

Saxagliptin na Metformin bikora bite?

Uyu muti uvanga ukora ukoresheje uburyo bubiri butandukanye kugira ngo ufashishe kugumisha isukari yawe mu maraso mu rugero rwiza. Igice cya saxagliptin gifasha umwijima wawe kurekura insuline nyinshi iyo isukari yawe mu maraso izamutse nyuma yo kurya, mugihe kandi kigabanya umubare wa glucose umwijima wawe ukora.

Igice cya metformin gikora cyane cyane kigabanya umubare w'isukari umwijima wawe ukora kandi ukohereza mu maraso yawe. Bifasha kandi imitsi yawe n'uturemangingo tw'ibinure guhinduka byoroshye kuri insuline, bivuze ko bishobora gukoresha glucose neza.

Muri rusange, iyi miti ibiri itanga icyo abaganga bita urwego rwo

Gerageza gufata imiti yawe ku gihe kimwe buri munsi kugira ngo urinde urugero rwawo mu mubiri wawe. Abantu benshi babona ko bifasha guhuza gufata imiti yabo n'amafunguro asanzwe, nk'ifunguro rya mu gitondo n'irya nimugoroba, kugira ngo bashyireho gahunda ihamye.

Mbere yo gutangira iyi miti, jya ufata ifunguro rito cyangwa agafunguro gato kugira ngo wirinde kutagira umunezero mu gifu. Ibifungurwa byoroshye mu gifu cyawe, nk'umugati wotsye, amakaramu, cyangwa ya yogati, bikora neza niba ufite impungenge zo kuruka.

Nzamara Igihe Kingana Iki Ndafata Saxagliptin na Metformin?

Ubwoko bwa 2 bwa diyabete ni indwara y'igihe kirekire, bityo abantu benshi bakeneye gufata iyi miti imyaka myinshi cyangwa ndetse itagira iherezo kugira ngo bagumane kugenzura isukari mu maraso. Muganga wawe azagenzura buri gihe urugero rwawe rwa isukari mu maraso n'ubuzima bwawe muri rusange kugira ngo amenye niba iyi miti ikomeje kuba igisubizo cyiza kuri wewe.

Mu mezi yawe ya mbere ukoresha iyi miti, birashoboka ko uzagira ibizamini byinshi kandi byo mu maraso kugira ngo wemeze ko ikora neza kandi itateza ibibazo. Nyuma yibyo, abantu benshi basuzumwa imiti yabo ya diyabete buri mezi atatu cyangwa atandatu.

Muganga wawe ashobora guhindura urugero rwawe cyangwa akaguha imiti itandukanye uko umubiri wawe uhinduka. Ibi ni ibisanzwe kandi ntibisobanura ko imiti itagikora - bisobanura gusa ko gahunda yawe yo kuvurwa irimo kunozwa ku buzima bwawe bwa none.

Ni Ibihe Bikorwa Bigaragara Biterwa na Saxagliptin na Metformin?

Kimwe n'indi miti yose, saxagliptin na metformin bishobora gutera ibikorwa bigaragara, nubwo abantu benshi babyihanganira neza. Ibikorwa bigaragara cyane akenshi biba byoroshye kandi akenshi birakosoka uko umubiri wawe wimenyereza imiti mu byumweru bya mbere.

Dore ibikorwa bigaragara bishobora kukubaho cyane, wibuke ko ibibazo bifitanye isano n'igifu ari byo byinshi:

• Uburwayi bwo kuruka cyangwa kutamererwa neza mu nda
• Impiswi cyangwa kwituma bireremye
• Umutwe
• Uburwayi bwo mu nzira yo hejuru yo mu myuka nk'ibicurane
• Uburyohe bw'icyuma mu kanwa kawe
• Kugabanyuka k'ipfa ryo kurya

Ibi bimenyetso rusange byo ku ruhande akenshi ni iby'igihe gito kandi birashoboka kubyitwaramo. Gufata umuti hamwe n'ibiryo no gutangira n'imiti mito bishobora gufasha kugabanya ibibazo byo mu nda.

Noneho, reka tuvuge ku ngaruka zimwe zitavugwa cyane ariko zikomeye zisaba ubufasha bwihutirwa bw'abaganga:

• Uburwayi bukomeye bwo mu nda butajya bucika
• Kuruka no kuruka bidahagarara
• Uburibwe budasanzwe bw'imitsi cyangwa intege nke
• Kugorana guhumeka cyangwa guhumeka vuba
• Uruhu rukomeye cyangwa ibiheri
• Ibimenyetso by'ibibazo by'impyiko nk'imihindukire yo kunyara

Nubwo izi ngaruka zikomeye zitaragera, ni ngombwa kuzimenya hakiri kare. Niba ubonye kimwe muri ibi bimenyetso, vugana n'umuganga wawe ako kanya cyangwa ushake ubufasha bw'ubuvuzi bwihutirwa.

Hariho kandi uburwayi butavugwa cyane ariko bukomeye bita lactic acidosis bushobora kubaho hamwe na metformin. Ibi bibaho iyo aside ya lactic yiyongera mu maraso yawe vuba kuruta uko umubiri wawe ushobora kuyikuramo. Ibimenyetso byo kwitondera birimo uburibwe budasanzwe bw'imitsi, kugorana guhumeka, uburwayi bwo mu nda, isereri, no kumva unaniwe cyane cyangwa warushye.

Ninde utagomba gufata Saxagliptin na Metformin?

Uyu muti ntabwo ukwiriye kuri buri wese, kandi umuganga wawe azasuzuma neza amateka yawe mbere yo kuwandikira. Abantu bafite uburwayi runaka cyangwa ibihe runaka bagomba kwirinda uyu muti uhuza rwose.

Ntugomba gufata uyu muti niba ufite diyabete yo mu bwoko bwa 1 cyangwa diyabete ketoacidosis, kuko yagenewe cyane gucunga diyabete yo mu bwoko bwa 2. Ntabwo kandi byemewe niba ufite allergie kuri saxagliptin, metformin, cyangwa izindi ngingo zose zikubiye mu muti.

Dore uburwayi bwihariye butuma uyu muti utakwiriye cyangwa bisaba kwitonda by'umwihariko:

• Indwara y'impyiko cyangwa imikorere y'impyiko yagabanutse
• Indwara y'umwijima cyangwa imyunyu y'umwijima yazamutse
• Amateka ya pankreatite (uburwayi bwa pankere)
• Kunanirwa k'umutima bisaba imiti
• Uburwayi bukomeye cyangwa indwara ikaze
• Amateka ya aside ya lactic

Muganga wawe azitonda kandi mu gutanga uyu muti niba uteganya kubagwa cyangwa gukora ibindi bizami by'ubuvuzi bisaba irangi, kuko bishobora kukugora guhagarika uyu muti mu gihe runaka.

Niba utwite, uteganya gutwita, cyangwa konka, ganira ibi na muganga wawe. Nubwo metformin rimwe na rimwe ikoreshwa mugihe cyo gutwita, umutekano wa saxagliptin mugihe cyo gutwita nturashimangirwa neza, bityo imiti isimbura ishobora kuba ikwiriye.

Amazina y'ubwoko bwa Saxagliptin na Metformin

Izina risanzwe ry'uyu muti uvanga ni Kombiglyze XR, ni verisiyo irekura gahoro gahoro ukoresha rimwe ku munsi. Hariho kandi verisiyo isanzwe ikoreshwa kabiri ku munsi.

Ushobora kandi kubona verisiyo rusange y'uyu muti uvanga, urimo ibikoresho bikora kimwe ariko bikorwa n'amasosiyete atandukanye y'imiti. Verisiyo rusange zifite akamaro nk'imiti y'amazina y'ubwoko kandi akenshi zihendutse.

Farumasi yawe ishobora gusimbuza verisiyo rusange keretse muganga wawe asabye izina ry'ubwoko. Ibi bisanzwe kandi bifite umutekano - ibikoresho bikora n'ubushobozi biracyahari.

Uburyo bwa Saxagliptin na Metformin

Niba uyu muti uvanga utakugendekeye neza cyangwa utera ingaruka zikomeye, hari imiti isimbura itandukanye. Muganga wawe ashobora kugufasha kubona umuti cyangwa uruvange rukora neza kubera uko ubuzima bwawe bumeze.

Izindi ntero za DPP-4 hamwe na metformin zirimo sitagliptin na metformin (Janumet) cyangwa linagliptin na metformin (Jentadueto). Izi zikora kimwe ariko zishobora kwihanganirwa neza nabantu bamwe.

Niba udashobora gufata metformin kubera ibibazo by'impyiko cyangwa ingaruka ziterwa n'imiti, muganga wawe ashobora kugusaba saxagliptin wenyine cyangwa akayihuza n'indi miti ya diyabete nka insuline cyangwa SGLT2 inhibitors.

Kubantu bakunda imiti iterwa, GLP-1 receptor agonists nka semaglutide cyangwa liraglutide birashobora kuba izindi nzira nziza zitanga uburyo bwo kugenzura isukari mu maraso kandi zishobora gufasha kugabanya ibiro.

Ese Saxagliptin na Metformin biruta Sitagliptin na Metformin?

Byombi saxagliptin na metformin (Kombiglyze) na sitagliptin na metformin (Janumet) ni imiti isa cyane ikora muburyo bumwe. Zombi ni inhibitors za DPP-4 zihujwe na metformin, kandi ubushakashatsi bwerekana ko zifite ubushobozi bungana bwo kugabanya urugero rwisukari mu maraso.

Gu hitamo hagati yiyi miti akenshi biterwa nibintu byihariye nk'ingaruka ziterwa n'imiti, koroshya imiti, igiciro, na assurance. Abantu bamwe bafata imiti imwe neza kuruta iyindi, nubwo abantu benshi babigenza neza hamwe na kimwe muri byombi.

Muganga wawe azatekereza ku buzima bwawe bwihariye, indi miti urimo gufata, nibyo ukunda mugihe uhitamo hagati yibi bintu. Byombi bifatwa nkibintu bifite umutekano kandi bikora neza muburyo bwo kuvura diyabete yo mu bwoko bwa 2.

Ibikunze Kubazwa Kuri Saxagliptin na Metformin

Q1. Ese Saxagliptin na Metformin bifite umutekano kubantu barwaye indwara z'umutima?

Muri rusange, iyi mvange ifatwa nkifite umutekano kubantu barwaye indwara z'umutima, kandi metformin ishobora no gutanga inyungu zimwe zo kurinda umutima. Ariko, muganga wawe azashaka kugukurikiranira hafi niba ufite umutima wanze gukora cyangwa izindi ndwara zikomeye z'umutima.

Umuti ntusanzwe utera ibibazo by'umutima ku bantu bafite ubuzima bwiza, ariko ni ngombwa kubwira muganga wawe ibibazo byose by'umutima ufite. Ashobora guhindura urugero rw'umuti ukoresha cyangwa agahitamo imiti itandukanye niba ufite uburwayi bukomeye bw'umutima.

Q2. Nakora iki niba nanyweye umuti wa Saxagliptin na Metformin mwinshi ku buryo butunguranye?

Niba unyweye uyu muti mwinshi ku buryo butunguranye, vugana na muganga wawe cyangwa ikigo gishinzwe kurwanya uburozi ako kanya, kabone n'iyo wumva umeze neza. Kunywa metformin nyinshi bishobora gutera uburwayi bukomeye bwa lactic acidosis, busaba ubufasha bwihuse bw'abaganga.

Reba ibimenyetso nk'ububabare budasanzwe mu misitsi, guhumeka bigoye, kuribwa mu nda, isereri, cyangwa kumva unaniwe cyane. Ntukegere kugeza ibimenyetso bigaragara mbere yo gushaka ubufasha - hamagara muganga wawe ako kanya niba wanyweye umuti mwinshi kuruta uko wategetswe.

Q3. Nakora iki niba nirengagije kunywa umuti wa Saxagliptin na Metformin?

Niba wibagiwe kunywa umuti, unywe ako kanya wibukiye, ariko niba bitari hafi y'igihe cyo kunywa umuti ukurikira. Niba igihe cyo kunywa umuti ukurikira kigeze, reka uwo wibagiwe hanyuma ukomeze gahunda yawe isanzwe.

Ntuzigere unywa imiti ibiri icyarimwe kugira ngo usubize umuti wibagiwe, kuko ibi bishobora kongera ibyago byo kugira ingaruka ziterwa n'umuti. Niba ukunda kwibagirwa kunywa imiti, tekereza gushyiraho ibyibutso kuri terefone yawe cyangwa ukoreshe igikoresho gifasha kwibuka imiti kugira ngo bigufashe gukurikiza gahunda.

Q4. Nshobora guhagarika ryari kunywa Saxagliptin na Metformin?

Ugomba guhagarika kunywa uyu muti gusa ukurikije ubuyobozi bwa muganga wawe. Diyabete yo mu bwoko bwa 2 ni uburwayi burambye, bityo abantu benshi bagomba gukomeza kunywa imiti ya diyabete igihe cyose kugira ngo bagumane urugero rwiza rw'isukari mu maraso.

Muganga wawe ashobora guhindura imiti ukoresha uko igihe kigenda gihita bitewe n'urugero rw'isukari mu maraso yawe, ingaruka ziterwa n'umuti, cyangwa impinduka mu buzima bwawe. Niba ufite impungenge zo kunywa umuti igihe kirekire, ganira ibyiyumvo byawe na muganga wawe - bashobora kugufasha gusobanukirwa inyungu no gukemura impungenge zose.

Q5. Nshobora kunywa inzoga niba ndimo gufata Saxagliptin na Metformin?

Ushobora kunywa inzoga mu rugero ruto kandi rimwe na rimwe, ariko ni ngombwa kwitonda. Inzoga irashobora kongera ibyago byo kurwara lactic acidosis, cyane cyane niba unywa cyane cyangwa ukanywa inzoga nyinshi icyarimwe.

Iyo unywa, nywa inzoga hamwe n'ibiryo kandi wigenzure ku kinyobwa kimwe ku munsi niba uri umugore cyangwa ibinyobwa bibiri ku munsi niba uri umugabo. Buri gihe ganira ku kunywa inzoga kwawe na muganga wawe, kuko ashobora gutanga inama zishingiye ku buzima bwawe muri rusange.