Sulfasalazine ni iki: Ibikoreshwa, Urutonde rw'imiti, Ingaruka ziterwa n'iyo miti n'ibindi

Sulfasalazine ni umuti wandikirwa na muganga uvanga ibintu bibiri bikora kugira ngo bigabanye umubyimbirwe mu mubiri wawe. Uyu muti umaze imyaka myinshi ufasha abantu guhangana n'indwara zifata amara n'ubwoko bumwe bwa rubagimpande, utanga ubufasha igihe umubiri wawe wikingira ukabije kandi ugatangira kurwanya ibice by'umubiri bifite ubuzima.

Ushobora kuba wibaza uko uyu muti ukora cyangwa niba ukwiriye indwara yawe. Reka tunyuremo ibyo byose ukeneye kumenya kuri sulfasalazine mu buryo busobanutse mu buzima bwawe bwa buri munsi.

Sulfasalazine ni iki?

Sulfasalazine ni umuti uvanga sulfapyridine na mesalamine (bita kandi aside ya 5-aminosalicylic). Tekereza nk'umuti ugamije kurwanya umubyimbirwe ukora by'umwihariko mu mara yawe no mu ngingo zawe kugira ngo utuze umubyimbirwe.

Uyu muti ubarirwa mu cyiciro cy'imiti yitwa imiti igabanya indwara ya rubagimpande (DMARDs) iyo ikoreshwa mu rubagimpande, na aminosalicylates iyo ikoreshwa mu ndwara zifata amara. Muganga wawe yarayikwandikiye kuko ishobora gufasha kugenzura uburyo indwara ikora, ntabwo ihisha gusa ibimenyetso.

Uyu muti uza mu buryo bw'ibinini bifatirwa mu kanwa. Ikintu cyihariye kuri sulfasalazine ni uko yagenewe kurekura ibintu byayo bikora neza aho bikenerwa cyane mu mubiri wawe.

Sulfasalazine ikoreshwa mu iki?

Sulfasalazine ikoreshwa cyane mu kuvura ulcerative colitis, indwara aho urukuta rw'amara yawe manini rubyimbirwa rukagira ibisebe. Ifasha gukiza igice cyangiritse kandi ikabuza ibibazo bishobora gutera kuva amaraso, impiswi, n'ububabare mu nda.

Uyu muti kandi uvura neza rubagimpande, cyane cyane iyo izindi miti itatanze ubufasha buhagije. Ishobora gufasha kugabanya kubyimba kw'ingingo, umuganda, n'ububabare mugihe gishobora kugabanya kwangirika kw'ingingo uko igihe kigenda.

Muganga wawe ashobora no kugusaba sulfasalazine kubera izindi ndwara ziterwa n'uburwayi, nubwo izi zidakunze kubaho. Abantu bamwe barwaye indwara ya Crohn cyangwa ubwoko bumwe na bumwe bwa artrite ya urubyiruko bashobora kungukira muri ubu buvuzi.

Sulfasalazine ikora ite?

Sulfasalazine ikora yibanda ku kubyimbirwa aho bituruka aho gusa guhisha ibimenyetso. Iyo ufata umuti, ujya mu mara yawe aho bagiteri nziza ziwugabanya mu bice byayo bibiri bikora.

Igice cya mesalamine kiguma mu mara yawe kandi kigabanya kubyimbirwa mu rukuta rw'amara. Hagati aho, igice cya sulfapyridine gishyirwa mu maraso yawe kandi gifasha kugenzura kubyimbirwa mu mubiri wawe wose, harimo no mu ngingo zawe.

Ibi bifatwa nk'umuti urwanya kubyimbirwa ukomeye ku rugero ruciriritse ushobora gufata ibyumweru byinshi kugeza ku mezi kugira ngo werekane ingaruka zawo zose. Si umuti ukemura ibintu vuba, ahubwo ni ubuvuzi burambye bufasha gucunga indwara ziterwa n'uburwayi burambye.

Nkwiriye gufata sulfasalazine nte?

Fata sulfasalazine nk'uko muganga wawe abitegeka, akenshi inshuro 2-4 ku munsi hamwe n'ibiryo cyangwa nyuma yo kurya. Kugira ibiryo mu gifu cyawe bifasha kugabanya ibibazo bishobora gutera mu gifu kandi bigateza imbere uburyo umubiri wawe wumva umuti.

Mimina ibinini byose hamwe n'ikirahure kinini cy'amazi. Ntugasenya, ntukore cyangwa utandukanye, kuko ibi bishobora kubangamira uburyo umuti usohoka mu mubiri wawe. Niba ugira ikibazo cyo kumira ibinini, ganira na muganga wawe kubyerekeye ubundi buryo.

Gerageza gufata imiti yawe mu gihe kimwe buri munsi kugira ngo ugumane urwego rwo hejuru rw'umuti mu mubiri wawe. Gushyiraho ibyibutsa kuri terefone birashobora kugufasha kwibuka, cyane cyane iyo utangiye kuvurwa kandi wubaka umuco.

Nywa amazi menshi umunsi wose mugihe ufata sulfasalazine. Ibi bifasha kwirinda ibibazo by'impyiko kandi bigabanya ibyago byo guteza ibuye ry'impyiko, rishobora kubaho rimwe na rimwe hamwe n'uyu muti.

Ndamara Minsi Ngarisha Sulfasalazine?

Igihe cyo gukoresha sulfasalazine giterwa n'uburwayi bwawe bwihariye n'uburyo umubiri wawe wakiriye imiti. Ku bantu barwaye ulcerative colitis, benshi bayikoresha amezi cyangwa imyaka kugira ngo bagumane ubuzima bwiza no kwirinda ibibazo.

Niba urimo gufata sulfasalazine kubera indwara ya rheumatoid arthritis, nawe uzakenera kuyikoresha igihe kirekire. Abantu benshi batangira kubona impinduka nyuma y'ibyumweru 6-12, ariko inyungu zose zirashobora gutwara amezi 6 kugira ngo zigaragare.

Ntuzigere uhagarika gufata sulfasalazine ako kanya utabanje kuvugana na muganga wawe. Guhagarika ako kanya bishobora gutuma ibimenyetso byawe bisubira cyangwa bikiyongera. Niba ukeneye guhagarika imiti, muganga wawe azagutegurira gahunda yo kugabanya urugero rwawe buhoro buhoro.

Ni Ibihe Bikorwa Bigaragara Bya Sulfasalazine?

Kimwe n'indi miti yose, sulfasalazine irashobora gutera ibikorwa bigaragara, nubwo atari buri wese ubyumva. Ibikorwa bigaragara byinshi ni bike kandi akenshi birakosoka uko umubiri wawe wimenyereza imiti mu byumweru bya mbere.

Ibikorwa bigaragara bisanzwe ushobora kubona harimo isesemi, kuribwa mu nda, kubabara umutwe, no kuribwa umutwe. Ibi akenshi bibaho iyo utangiye gufata imiti bwa mbere kandi akenshi birakosoka uko igihe kigenda.

Dore ibikorwa bigaragara bikunda kubaho cyane:

• Isesemi no kuribwa mu nda
• Kubura ubushake bwo kurya
• Kubabara umutwe
• Kuribwa umutwe
• Kuruka
• Kugira umunaniro

Ibi bikorwa bigaragara bisanzwe birashobora gucungwa kandi ntibigomba kukubuza gukomeza kuvurwa niba imiti ifasha uburwayi bwawe.

Abantu bamwe bashobora guhura n'ibikorwa bigaragara bikomeye bisaba ubufasha bwihutirwa bwa muganga. Nubwo ibi bidakunze kubaho, ni ngombwa kubimenya kugira ngo ushobore gushaka ubufasha niba bibaye ngombwa.

Vugana na muganga wawe ako kanya niba uhuye n'ibi bikorwa bigaragara bikomeye:

• Uburibwe bukomeye mu nda cyangwa kuruka bidahagarara
• Ibimenyetso by’ibibazo by’umwijima (uruhu cyangwa amaso y’umuhondo, inkari z’umukara, umunaniro udashira)
• Ukuva amaraso cyangwa gukomereka bidasanzwe
• Umutwe ukabije cyangwa impinduka mu iyerekwa
• Ibimenyetso byo kugabanuka kw'insoro (indwara zikunze kubaho, umunaniro udasanzwe, uruhu rworoshye)
• Uruhu ruruka cyangwa kuribwa cyane
• Kugorana guhumeka cyangwa kubabara mu gituza

Ibi bimenyetso bishobora kwerekana ibibazo bikomeye bisaba isuzuma n'ubuvuzi bwihuse.

Mu buryo butajegajega, sulfasalazine ishobora gutera ingaruka zikomeye cyane zirimo allergie zikomeye, indwara z'amaraso, cyangwa kwangirika kw'umwijima. Nubwo ibi bibazo bidakunze kubaho, muganga wawe azagukurikiranira ibizamini by'amaraso bya buri gihe kugirango amenye ibibazo byose hakiri kare.

Ninde utagomba gufata Sulfasalazine?

Sulfasalazine ntibishoboka kuri buri wese, kandi ibintu bimwe na bimwe bituma bitakwemerwa cyangwa bisaba ingamba zidasanzwe. Muganga wawe azasuzuma amateka yawe y'ubuvuzi neza mbere yo gutanga uyu muti.

Ntabwo ugomba gufata sulfasalazine niba ufite allergie ku miti ya sulfa, aspirine, cyangwa salicylates. Abantu bafite indwara zikomeye z'impyiko cyangwa umwijima nabo ntibakunze gufata uyu muti mu buryo bwizewe.

Ibyiciro byinshi bisaba kwitonda cyane no gukurikiranwa neza niba ukeneye kuvurwa na sulfasalazine:

• Indwara z'impyiko cyangwa amateka y'amabuye y'impyiko
• Indwara y'umwijima cyangwa imyunyu y'umwijima yazamutse
• Indwara z'amaraso cyangwa umubare muto w'insoro
• Asima cyangwa allergie zikomeye
• G6PD deficiency (ikibazo cy'imiterere)
• Porphyria (indwara idasanzwe y'amaraso)

Niba ufite kimwe muri ibi bibazo, muganga wawe ashobora gukomeza gutanga sulfasalazine ariko azagukurikiranira hafi n'ibizamini by'amaraso bya buri gihe no kugenzura.

Gusama no konsa nabyo bisaba kubitekerezaho byihariye. Nubwo sulfasalazine ishobora gukoreshwa mugihe cyo gutwita iyo bibaye ngombwa, yinjira mu mata kandi ishobora kugira ingaruka ku mwana wonka.

Amazina y'ubwoko bwa Sulfasalazine

Sulfasalazine iboneka mu mazina y'ubwoko butandukanye, nka Azulfidine akaba ari ryo zina rizwi cyane. Ushobora kandi kubona yanditswe nka Azulfidine EN-tabs, ibi bikaba ari ibinini bifite umwihariko wo kuba byoroshye mu gifu cyawe.

Ubwoko bwa sulfasalazine butagira izina ry'ubwoko buraboneka cyane kandi bukora neza nk'ubwoko bw'amazina. Farumasi yawe ishobora guhita ishyiraho ubwoko butagira izina ry'ubwoko keretse muganga wawe asabye by'umwihariko izina ry'ubwoko.

Uko waba urimo gufata izina ry'ubwoko cyangwa ubwoko butagira izina ry'ubwoko, ibikoresho bikora n'ubushobozi bikomeza kuba kimwe. Itandukaniro rikuru rishobora kuba mu bintu bitagira akamaro cyangwa imiterere y'ibinini.

Uburyo bwa Sulfasalazine bwakoreshwa mu mwanya wayo

Niba sulfasalazine itagukundiye cyangwa ikagutera ingaruka zidakunda, imiti myinshi yindi ishobora kuvura indwara zisa. Uburyo bwiza bwakoreshwa mu mwanya wayo buterwa n'uburwayi bwawe bwihariye n'amateka yawe y'ubuvuzi.

Kubera ulcerative colitis, uburyo bwakoreshwa mu mwanya wayo burimo mesalamine (Asacol, Pentasa), ikaba ari kimwe mu bice bikora muri sulfasalazine ariko nta gice cya sulfa. Izindi nzira zirimo corticosteroids, ibitera ubudahangarwa nka azathioprine, cyangwa imiti mishya ya biyolojiya.

Kubera rheumatoid arthritis, DMARDs zindi zirimo methotrexate, hydroxychloroquine, cyangwa leflunomide. Imiti ya biyolojiya nka adalimumab cyangwa etanercept nayo ishobora kuba inzira zikoreshwa mu gihe indwara zikomeye.

Muganga wawe azagufasha kubona uburyo bukwiye bushingiye ku bimenyetso byawe, amateka yawe y'ubuvuzi, n'uburyo wabyitwayemo ku bundi buvuzi.

Ese Sulfasalazine iruta Mesalamine?

Sulfasalazine na mesalamine byombi ni imiti ikora neza kuri ulcerative colitis, ariko bikora mu buryo butandukanye kandi bifite inyungu zihariye. Guhitamo hagati yabyo biterwa n'ikibazo cyawe cyihariye n'uburyo wihanganira ingaruka ziterwa n'iyo miti.

Sulfasalazine ishobora gukora neza ku bantu bamwe kuko ikubiyemo ibintu bibiri bikora icyarimwe. Ariko, mesalamine ikunda gutera ingaruka nke kuko ntikubiyemo igice cya sulfa abantu bamwe bashobora kwitwaraho.

Mesalamine akenshi ikoreshwa ku bantu bafite allergie kuri imiti ya sulfa cyangwa bafite ingaruka zikomeye za sulfasalazine. Iboneka kandi mu buryo butandukanye bushobora kugera ahantu runaka mu mara.

Muganga wawe azatekereza ibintu nk'uburemere bw'ibimenyetso byawe, uburyo wabanje kuvurwa, n'ibintu byongera ibyago mugihe afata icyemezo cy'umuti ushobora gukora neza kuri wowe.

Ibikunze Kubazwa Kuri Sulfasalazine

Ese Sulfasalazine irakoreshwa neza ku bantu barwaye indwara z'umutima?

Sulfasalazine muri rusange ifatwa nk'umuti ukoreshwa neza ku bantu barwaye indwara z'umutima, kandi ubushakashatsi bumwe buvuga ko bushobora no kugira akamaro ku mutima. Uyu muti ushobora gufasha kugabanya umubyimbire mu mubiri wose, bishobora kugabanya ibyago by'ibibazo by'umutima bifitanye isano n'indwara zidakira ziterwa n'umubyimbire.

Ariko, ugomba buri gihe kumenyesha muganga wawe ibibazo byose by'umutima mbere yo gutangira gukoresha sulfasalazine. Bashobora gushaka kugukurikiranira hafi cyangwa guhindura imiti yindi urimo gufata kubera indwara z'umutima.

Nkwiriye gukora iki niba nanyoye sulfasalazine nyinshi bitunguranye?

Niba utunguranye ukanywa sulfasalazine nyinshi kuruta uko byategetswe, vugana na muganga wawe cyangwa ikigo gishinzwe gukumira uburozi ako kanya. Kunywa nyinshi bishobora gutera ingaruka zikomeye zirimo isesemi ikabije, kuruka, urujijo, ndetse n'imihindukire iteye akaga mu mikorere y'amaraso.

Ntugerageze kwivuruguta keretse niba ubitegetswe n'abaganga. Niba ufite ibimenyetso bikomeye nk'ingorane zo guhumeka, kuribwa mu gituza, cyangwa gutakaza ubwenge, hamagara 911 cyangwa ujye mu cyumba cyihutirwa cyegereye ako kanya.

Nkwiriye gukora iki niba nirengagije urugero rwa sulfasalazine?

Niba wibagiwe gufata urugero rwa sulfasalazine, rufate uko wibukije, keretse igihe cyo gufata urugero rukurikira cyegereje. Muri urwo rubanza, reka urugero wibagiwe, maze ufate urugero rukurikira ku gihe cyagenwe.

Ntuzigere ufata urugero ebyiri icyarimwe kugira ngo usubize urugero wibagiwe, kuko ibyo bishobora kongera ibyago byo kugira ingaruka zidakunzwe. Niba ukunda kwibagirwa gufata imiti, tekereza gushyiraho alarme cyangwa gukoresha igikoresho cyo gutegura imiti kugira ngo bikufashe kwibuka.

Ni ryari nshobora kureka gufata sulfasalazine?

Ugomba kureka gufata sulfasalazine gusa uyobowe na muganga wawe. Ku bantu benshi bafite ulcerative colitis cyangwa rheumatoid arthritis, sulfasalazine ni imiti ifatwa igihe kirekire ifasha kugenzura uburwayi buri hasi.

Niba ushaka kureka gufata umuti, banza ubiganireho na muganga wawe. Ashobora kugufasha gusobanukirwa ibyago n'inyungu byo kureka kandi ashobora gutanga igitekerezo cyo kugabanya urugero buhoro buhoro kugira ngo wirinde ibimenyetso byo kongera uburwayi.

Nshobora kunywa inzoga nkanwa sulfasalazine?

Kunywa inzoga mu rugero ruciriritse muri rusange birashoboka mugihe ufata sulfasalazine, ariko ni byiza kubiganiraho na muganga wawe. Inzoga na sulfasalazine byombi bishobora kugira ingaruka ku mwijima wawe, bityo kubihuza bishobora kongera ibyago byo kugira ibibazo by'umwijima.

Niba uhisemo kunywa inzoga, bikore mu rugero ruciriritse kandi umenye ibimenyetso bidasanzwe nk'umunaniro, isesemi, cyangwa kuribwa mu nda bishobora kugaragaza ko umwijima urimo kurakara. Muganga wawe ashobora kugusaba kwirinda inzoga rwose niba ufite ibibazo by'umwijima cyangwa izindi mpamvu zishobora gutera ibibazo.