Icyo Tedizolid ari cyo: Ibyo ikoreshwa, urugero rwo gufata, ingaruka ziterwa n'iyo miti n'ibindi

Tedizolid ni umuti wandikirwa na muganga urwanya mikorobe zikomeye, cyane cyane iziterwa na bagiteri zirwanya imiti nka MRSA. Uyu muti ubarizwa mu cyiciro gishya cy'imiti yitwa oxazolidinones, yakozwe kugira ngo irwanye indwara zidakira n'imiti isanzwe.

Muganga wawe ashobora kukwandikira tedizolid igihe urwaye indwara z'uruhu, umusonga, cyangwa izindi ndwara ziterwa na bagiteri zikeneye uburyo bukomeye bwo kuvurwa. Ifatwa nk'umuti ukomeye ukoreshwa cyane cyane mu bihe bikomeye aho izindi miti itashobora gukora neza.

Tedizolid ikoreshwa mu kuvura iki?

Tedizolid ivura indwara ziterwa na bagiteri akenshi zirwanya izindi miti. Muganga wawe azakwandikira uyu muti igihe akeneye uburyo bwizewe bwo kurwanya bagiteri zikomeye ziteza indwara zikomeye.

Ibikoreshwa cyane birimo kuvura indwara z'uruhu n'imitsi yoroshye, nka selulite, ibibyimba, n'indwara z'ibikomere. Izi ndwara zirashobora kurya ububabare kandi ntizishobora kwitabira neza imiti isanzwe, bituma tedizolid iba uburyo bwiza bwo kuvura.

Abaganga bakoresha kandi tedizolid mu kuvura ubwoko bumwe na bumwe bwa umusonga, cyane cyane umusonga uterwa n'abarwayi bari mu bitaro aho bagiteri zirwanya imiti zibangamiye. Uyu muti ushobora gufasha cyane cyane niba waragumye mu bitaro ukagira indwara itoroshye kuvura.

Mu bihe bimwe na bimwe, abaganga bandikira tedizolid indwara z'amagufa n'imitsi ihujwe, indwara z'amaraso, cyangwa izindi ndwara zikomeye ziterwa na bagiteri igihe ibizamini byo muri laboratori byerekana ko bagiteri zirwanya imiti ikoreshwa mbere.

Tedizolid ikora ite?

Tedizolid ikora ihagarika bagiteri gukora poroteyine zikeneye kugira ngo zibaho kandi zigwize. Tekereza nk'uko ihungabanya ubushobozi bwa bagiteri bwo kubaka ibintu byingenzi, amaherezo bigatuma zipfa.

Uyu muti ufatwa nk'umuti w'ingufu wica mikorobe wibanda by'umwihariko ku buryo poroteyine ikorwa na bagiteri. Ifatana n'igice cya bagiteri cyitwa ribozome, kimeze nk'uruganda rwabo rwa poroteyine, kandi irabibuza gukora neza.

Igituma tedizolid ikora neza cyane ni ubushobozi bwayo bwo kurwanya bagiteri zateje ubwivumbagatanye ku yindi miti yica mikorobe. Bagiteri nyinshi zivumbagatanye zabonye uburyo bwo kunyura ku miti yica mikorobe ya kera, ariko tedizolid ikoresha uburyo butandukanye bushobora kuzigeraho no kuzihagarika.

Uyu muti wibanda cyane mu bice byanduye, bivuze ko ushobora kugera aho ikibazo kiri neza. Ibi bishobora kwinjira mu bice by'umubiri ni ingenzi cyane cyane ku ndwara z'uruhu na nyumoniya, aho umuti wica mikorobe ukeneye kugera ahantu hakwiye kugira ngo ukore akazi kawo.

Nkwiriye gufata gute Tedizolid?

Fata tedizolid nk'uko muganga abikwandikiye, akenshi rimwe ku munsi hamwe n'ibiryo cyangwa utabifatanije. Urutonde rusanzwe ni 200 mg rimwe ku munsi, ariko muganga wawe azagena urugero rukwiye hashingiwe ku ndwara yawe yihariye n'ubuzima bwawe.

Ushobora gufata uyu muti hamwe n'ibiryo niba bigutera isesemi, nubwo ibiryo bitagira ingaruka zikomeye ku buryo umubiri wawe uwufata. Abantu bamwe basanga kuwufata hamwe n'ifunguro rito cyangwa akamanyu bifasha kwirinda isesemi cyangwa kutumva neza mu gifu.

Gerageza gufata urugero rwawe ku gihe kimwe buri munsi kugira ngo ugumane urugero rwawo mu mubiri wawe. Gushyiraho umwanya wo kwibutsa buri munsi birashobora kugufasha kuguma mu murongo w'imiti yawe.

Mimina ikinini cyose hamwe n'amazi - ntukimenagure, ntukicagagure, cyangwa ngo ukimene. Niba ugira ikibazo cyo kumira ibinini, ganira na muganga wawe ku bindi bishobora kuboneka.

Mugihe ufata tedizolid, ugomba kwirinda kurya ibiryo byinshi birimo tyramine nyinshi, nk'amakeze ashaje, inyama zitunganyirijwe, n'ibiryo byabitswe. Ibi biryo bishobora guhura n'umuti kandi bishobora gutera impinduka mu mitsi y'amaraso.

Nkwiriye kumara igihe kingana iki mfata Tedizolid?

Abantu benshi bafata tedizolid mu minsi 6 kugeza kuri 12, bitewe n'ubwoko n'uburemere bw'ubwandu bwabo. Muganga wawe azagena igihe nyacyo bitewe n'uko umubiri wawe witwara ku buvuzi n'agakoko gatera ubwandu bwihariye.

Ku bwandu bw'uruhu n'imitsi yoroshye, uburyo bwo kuvura busanzwe ni iminsi 6. Iki gihe kigufi ni kimwe mu byiza bya tedizolid ugereranije na zimwe mu zindi antibiyotike zishobora gukenerwa gufatwa igihe kirekire.

Niba uvurwa umusonga cyangwa ubwandu bukomeye, muganga wawe ashobora kongera igihe cyo kuvura kikagera ku minsi 7 kugeza kuri 12. Bazakurikirana uko urimo utera imbere kandi bagahindura igihe niba bibaye ngombwa bitewe n'uko urimo witwara neza.

Ni ngombwa kurangiza uburyo bwose bwo kuvura, kabone n'iyo watangira kumva urushijeho nyuma y'iminsi mike. Guhagarika kare bishobora korohereza bagiteri kubaho kandi bikaba byateza imbere ubudahangarwa, bigatuma ubwandu bw'ahazaza bugorana kuvura.

Muganga wawe ashobora gushaka kukubona mu gihe cyo gukurikirana kugira ngo yemeze ko ubwandu burimo burakira neza. Ntugatinye kubavugisha niba ibimenyetso byawe birushaho cyangwa ntibigenda neza nyuma y'iminsi mike uvurwa.

Ni Ibihe Bikorwa Bigaragara Byatewe na Tedizolid?

Kimwe n'imiti yose, tedizolid ishobora gutera ibikorwa bigaragara, nubwo abantu benshi bayihanganira neza. Ibikorwa bigaragara byinshi ni bike kandi by'igihe gito, bikemuka uko umubiri wawe wimenyereza umuti cyangwa nyuma yo kurangiza kuvurwa.

Ibikorwa bigaragara cyane ushobora guhura nabyo birimo isesemi, kubabara umutwe, na diarrea. Ibi bimenyetso mubisanzwe birashoboka kandi ntibisaba guhagarika umuti keretse bibaye bikomeye.

Dore ibikorwa bigaragara bikunze kugaragara abantu bamwe bahura nabyo:

• Isesemi no kuribwa mu nda
• Kubabara umutwe
• Diarrea
• Uruzi
• Kunanirwa cyangwa gucika intege
• Kuruka
• Urugo rw'uruhu cyangwa kurigata

Ibi bimenyetso byo ku ruhande bisanzwe bikunda kuba byoroheje kandi bikagenda bikira uko umubiri wawe umenyera umuti. Niba bikomeje cyangwa bikaba bibangamiye, muganga wawe ashobora gutanga inama z'uko wabigenza.

Abantu bamwe bashobora kugira ibimenyetso byo ku ruhande bikomeye bisaba ubufasha bwihuse bw'abaganga. Nubwo ibi bidakunze kubaho, ni ngombwa kubimenya kugirango usabe ubufasha niba bibaye ngombwa.

Vugana n'umuganga wawe ako kanya niba ubonye kimwe muri ibi bimenyetso bikomeye:

• Impiswi ikabije ishobora kuvamo amaraso
• Ibimenyetso by'umuvuduko ukabije w'amaraso nk'umutwe ukabije cyangwa impinduka mu mbono
• Ibimenyetso byo kugabanuka kw'uturemangingo tw'amaraso nk'ibikomere bidasanzwe cyangwa kuva amaraso
• Urugero rukabije rwo kwivumbura ku miti hamwe no guhumeka bigoranye cyangwa kubyimba
• Ubumuga buhoraho cyangwa kuribwa mu ntoki cyangwa mu birenge
• Urubavu rukabije cyangwa kubabara mu nda

Gahoro cyane, tedizolid ishobora gutera indwara yitwa serotonin syndrome, cyane cyane niba ufata indi miti igira ingaruka ku rwego rwa serotonin. Iyi ni indwara ikomeye isaba ubufasha bwihuse bw'abaganga.

Gukoresha tedizolid igihe kirekire (ibyo bidakunze kubaho) bishobora kugira ingaruka ku turemangingo tw'amaraso yawe cyangwa gutera ibibazo by'imitsi. Muganga wawe azakugenzura neza niba ukeneye kuvurwa igihe kirekire.

Ninde utagomba gufata Tedizolid?

Tedizolid ntibereye buri wese, kandi muganga wawe azasuzuma neza amateka yawe y'ubuzima mbere yo kuyandika. Indwara zimwe na zimwe n'imiti bishobora gutuma tedizolid itaba umutekano cyangwa idakora neza kuri wowe.

Ntugomba gufata tedizolid niba uyirwaye cyangwa imiti isa nayo ya antibiyotike nka linezolid. N'iyo utazi neza ibyerekeye allergie, bwire muganga wawe ku byerekeye ibimenyetso byose byabayeho byerekeye antibiyotike.

Abantu bafata imiti imwe na imwe igabanya ububabare, cyane cyane MAO inhibitors, bagomba kwirinda tedizolid kubera imikoranire ishobora guteza akaga. Muganga wawe azasuzuma imiti yawe yose kugirango arebe niba hariho ibinyuranyo.

Ibi ni ibihe bishobora gutuma tedizolid ikoreshwa witonze cyane cyangwa ikaba idakwiriye:

• Indwara ikomeye y'impyiko cyangwa umwijima
• Amateka y'indwara z'amaraso cyangwa ibibazo byo mu bwonko
• Gufata imiti ivura umubabaro cyangwa guhangayika
• Umubyimba ukabije utagendera ku murongo
• Amateka y'ibibazo by'imitsi cyangwa neuropathy
• Gusama cyangwa konsa

Niba ufite kimwe muri ibi bibazo, muganga wawe azagereranya inyungu n'ibibazo bishobora kuvuka, ashobora guhitamo umuti w'abaganga utandukanye cyangwa akagukurikiranira hafi mugihe uvurwa.

Abana n'abarwayi bageze mu zabukuru bashobora gukenera ibipimo byihariye cyangwa gukurikiranwa hafi. Muganga wawe azahindura gahunda yo kuvura bitewe n'imyaka n'ubuzima muri rusange.

Amazina ya Tedizolid

Tedizolid iboneka munsi y'izina ry'ubucuruzi rya Sivextro mu bihugu byinshi. Ubu ni bwo buryo busanzwe uzabona yanditswe kandi itangwa muri farumasi.

Uturere tumwe dushobora kugira amazina y'ubucuruzi atandukanye cyangwa verisiyo rusange ziboneka. Umufarmasi wawe ashobora kugufasha kumenya igicuruzwa runaka urimo kwakira no kumenya neza ko usobanukirwa uburyo bwo kuyifata neza.

Niba wakira izina ry'ubucuruzi cyangwa verisiyo rusange, ibikoresho bikora n'imikorere birasa. Muganga wawe azagena verisiyo ikwiriye kuvurwa kwawe.

Uburyo bwo gusimbuza Tedizolid

Niba tedizolid itagukwiriye, indi miti myinshi y'abaganga ishobora kuvura indwara zisa. Muganga wawe azahitamo igisubizo cyiza bitewe n'indwara yawe, amateka yawe y'ubuvuzi, n'agakoko karimo.

Linezolid ni igisubizo gisa cyane, kiva mu cyiciro kimwe cy'imiti y'abaganga. Ikora mu buryo busa ariko ishobora gufatwa kabiri ku munsi aho gufatwa rimwe ku munsi nka tedizolid.

Izindi nzira muganga wawe ashobora gutekereza zirimo vancomycin, daptomycin, cyangwa clindamycin, bitewe n'ubwoko bw'indwara n'uburyo bagiteri zirwanya imiti. Buri kimwe gifite inyungu zacyo n'ibitekerezo.

Ku ndwara zimwe zo ku ruhu, imiti yica mikorobe ikoreshwa ku ruhu nka mupirocin ishobora kuba ihagije. Muganga wawe azemeza niba imiti ikoreshwa ku ruhu ishobora gukemura neza ikibazo cyawe.

Ese Tedizolid iruta Linezolid?

Tedizolid itanga inyungu nyinshi kurusha linezolid, nubwo byombi ari imiti yica mikorobe ikora neza ku ndwara ziterwa na bagiteri zirwanya imiti. Inyungu nyamukuru ya tedizolid ni uko ifatwa rimwe ku munsi ugereranije na linezolid ifatwa kabiri ku munsi.

Ubushakashatsi burerekana ko tedizolid ishobora gukora neza nka linezolid mu kuvura indwara zo ku ruhu, hamwe n'ingaruka nke zishobora kugaragara. Abarwayi benshi basanga gufata umuti rimwe ku munsi byoroshye kandi byoroshye kwibuka.

Tedizolid kandi isa nkaho itagira ingaruka nyinshi ku mubare w'uturemangingo tw'amaraso ugereranije na linezolid, cyane cyane mu gihe cyo kuvurwa gito. Ibi bishobora kuba ikintu cy'ingenzi ku bantu bafite indwara z'amaraso cyangwa abafata indi miti igira ingaruka ku turemangingo tw'amaraso.

Ariko, linezolid imaze igihe kinini ikoreshwa kandi ifite ubushakashatsi bwinshi buyishyigikiye. Muganga wawe azatekereza ibintu nk'ikiguzi, uko iboneka, n'ikibazo cyawe cyihariye cy'ubuvuzi mugihe uhitamo hagati yiyi miti.

Imiti yombi ifatwa nk'imiti ikomeye yo kuvura indwara zirwanya imiti, kandi guhitamo akenshi biterwa n'ibintu bifatika nk'uburyo bwo gufata umuti n'uburyo wowe ubwawe witwara ku miti.

Ibikunze Kubazwa Kuri Tedizolid

Ese Tedizolid irakwiriye abarwayi ba diyabete?

Tedizolid muri rusange irakwiriye abarwayi ba diyabete, ariko bisaba gukurikiranwa neza. Uyu muti ntugira ingaruka zigororotse ku rugero rw'isukari mu maraso, ariko indwara ubwazo zirashobora gutuma gucunga diyabete bigorana.

Muganga wawe azagenzura isukari yo mu maraso yawe yitonze mugihe uvurwa, cyane cyane niba urwaye diyabete idakira. Abantu bamwe basanga urugero rw'isukari yo mu maraso yabo ruhindagurika cyane mugihe bavurwa n'imiti yica mikorobe bitewe n'umunaniro wo kurwanya indwara.

Niba ufata imiti ya diyabete, ikomeze nkuko byategetswe keretse muganga wawe abiguhayeho inama zitandukanye. Ubufatanye bwa tedizolid n'imiti ya diyabete mubisanzwe buratekanye mugihe bigenzurwa neza.

Nkwiriye gukora iki niba mfashwe n'umuti wa tedizolid mwinshi?

Niba ufashwe n'umuti mwinshi kuruta urugero wategetswe, vugana na muganga wawe cyangwa abaganga b'uburozi ako kanya. Gufata tedizolid nyinshi bishobora kongera ibyago byo kugira ingaruka ziterwa n'umuti, cyane cyane izo zireba umuvuduko w'amaraso yawe n'imitsi.

Ntugerageze gusimbura urugero rwinshi wanyoye wirinda gufata urugero rukurikira rwateganijwe. Ahubwo, komeza gahunda yawe isanzwe yo gufata imiti nyuma yo kubona inama z'ubuvuzi ku birebana no kunywa imiti mwinshi.

Ibimenyetso byo kunywa imiti myinshi bishobora kuba kubabara umutwe cyane, isereri, isesemi, cyangwa impinduka mu muvuduko w'amaraso. Shakisha ubufasha bw'ubuvuzi ako kanya niba ubonye ibimenyetso bibangamiye nyuma yo kunywa imiti y'inyongera.

Nkwiriye gukora iki niba nirengagije urugero rwa tedizolid?

Niba wirengagije urugero, rinywe ako kanya wibukiye, keretse igihe cyegereje cyo gufata urugero rukurikira rwateganijwe. Muricyo gihe, irengagize urugero wibagiwe ukomeze gahunda yawe isanzwe.

Ntuzigere ufata urugero ebyiri icyarimwe kugirango usimbure urugero wibagiwe. Ibi bishobora kongera ibyago byo kugira ingaruka ziterwa n'umuti utagize icyo wongera mu kuvura indwara yawe.

Niba ukunda kwibagirwa urugero, shyiraho ibyibutso kuri terefone yawe cyangwa ukoreshe umuteguro w'imiti. Gufata imiti buri gihe bifasha kumenya neza ko umuti ukora neza mu gukiza indwara yawe.

Nshobora guhagarika ryari gufata tedizolid?

Reka gukoresha tedizolid gusa igihe muganga wawe abikubwiye, n'iyo wumva umeze neza rwose. Gusoza urugendo rwose rw'imiti ni ngombwa kugira ngo ukureho rwose mikorobe kandi wirinde ubushobozi bwo kurwanya imiti.

Urugero rwinshi rwa tedizolid ni rugufi (iminsi 6-12), bityo birashoboka ko uzarangiza umuti wose utagomba guhagarara hakiri kare. Muganga wawe azategura gahunda yo gusuzuma kugira ngo yemeze ko icyorezo cyashize.

Niba uhuye n'ingaruka zikomeye, vugana n'umuganga wawe ako kanya aho guhagarika umuti ku giti cyawe. Barashobora kugufasha gucunga ingaruka cyangwa guhindura kuri antibiyotike itandukanye niba bibaye ngombwa.

Nshobora kunywa inzoga nkorera tedizolid?

Nubwo nta mikoranire ya ngombwa iri hagati ya tedizolid na alukolo, muri rusange ni byiza kwirinda kunywa mu gihe urwana n'icyorezo. Alukolo irashobora kubuza umubiri wawe gukira kandi irashobora gukomeza ingaruka zimwe na zimwe nka isesemi cyangwa isereri.

Niba uhisemo kunywa, bikore mu rugero ruto kandi witondere uko wumva. Abantu bamwe basanga alukolo ituma ingaruka za antibiyotike zigaragara cyane cyangwa zitanezeza.

Shyira imbaraga mu kuguma ufite amazi menshi kandi uruhuke bihagije kugira ngo ushyigikire gukira kwawe. Umubiri wawe ukeneye imbaraga zo kurwanya icyorezo, kandi alukolo irashobora kubuza iyi nzira yo gukira.