Ticagrelor ni iki: Ibikoreshwa, Uburyo bwo gukoresha, Ingaruka ziterwa nacyo n'ibindi

Ticagrelor ni umuti wandikirwa n'abaganga ugabanya amaraso ufasha kwirinda amaraso avurirana ateza akaga mu miyoboro y'amaraso yawe. Muganga wawe ashobora kukwandikira uyu muti niba waragize umutima utera cyane, igihuhusi, cyangwa ibikorwa bimwe na bimwe by'umutima, kuko ukora ubu ukumira uturemangingo tw'amaraso yawe kwifatanya byoroshye.

Uyu muti ubarirwa mu cyiciro cy'imiti yitwa antiplatelet agents, itandukanye n'indi miti igabanya amaraso ushobora kuba uzi. Tekereza nk'umurinzi woroshye ariko ukora neza ufasha amaraso yawe gutembera neza mu miyoboro yawe, ugabanya ibyago by'ibibazo by'umutima mu gihe kizaza.

Ticagrelor ikoreshwa mu iki?

Ticagrelor ikoreshwa cyane cyane mu kurinda amaraso avurirana mu bantu bafite indwara ya coronary syndrome cyangwa bafite amateka y'umutima utera cyane. Muganga wawe arayikwandikira iyo imiyoboro y'amaraso y'umutima wawe ikeneye uburinzi bwihariye kuva mu kuvurirana kw'amaraso guteza akaga.

Uyu muti akenshi uhabwa abarwayi bamaze kugira umutima utera cyane cyangwa angina itajegajega. Ikoreshwa kandi hamwe na aspirine mu byo abaganga bita "ubuvuzi bwa antiplatelet bubiri," butanga uburinzi bukomeye kurusha gukoresha umuti umwe ugabanya amaraso wenyine.

Muganga wawe ashobora kandi kukwandikira ticagrelor niba waragize ibikorwa bimwe na bimwe by'umutima nk'ishyirwa rya stent. Muri ibi bihe, kwirinda kuvurirana kw'amaraso ni ngombwa kugira ngo ukire kandi ugire ubuzima bw'umutima burambye.

Ticagrelor ikora ite?

Ticagrelor ikora ibara ibice byihariye ku turemangingo tw'amaraso yawe twitwa P2Y12 receptors. Ibi birinda uturemangingo twawe tw'amaraso kwegerana no gukora amaraso avurirana ashobora guhagarika itembera ry'amaraso mu mutima wawe cyangwa mu bwonko bwawe.

Bitandukanye n'indi miti igabanya amaraso, ticagrelor ifatwa nk'umuti usubirwamo, bisobanura ko ingaruka zayo zishobora gushira vuba iyo uhagaritse kuwufata. Ibi bituma uba umuti ukomeye mu rugero ruciriritse utanga uburinzi bukora neza mu gihe utanga ubworoherane mu kuvura.

Umuti utangira gukora nyuma y'amasaha make uwufashe, kandi ugera ku ngaruka zawo zose nyuma y'amasaha 2-4. Ibi bifasha vuba gutanga uburinzi bw'umutima n'imitsi ukeneye nta gutinda.

Nkwiriye gufata Ticagrelor nte?

Fata ticagrelor nk'uko umuganga wawe abikwandikiye, akenshi kabiri ku munsi ufata cyangwa utafata ibiryo. Urashobora kuyifata n'ikirahure cy'amazi, kandi ntacyo bitwaye niba urya mbere cyangwa nyuma yo gufata umuti.

Abantu benshi bafata urupapuro rumwe mu gitondo n'urundi nimugoroba, bakabanza amasaha 12. Gerageza gufata imiti yawe ku gihe kimwe buri munsi kugirango bifashe kugumisha urugero rwawo mu mubiri wawe.

Niba ugira ikibazo cyo kumira ibinini, urashobora kubisakaza ukabivanga n'amazi, ariko banza ubaze umufarimasi. Ntukigere uhagarika gufata ticagrelor mu buryo butunguranye utabanje kuvugana n'umuganga wawe, kuko ibi bishobora kongera ibyago byo kuvura amaraso.

Nkwiriye gufata Ticagrelor igihe kingana iki?

Igihe cyo kuvurwa na ticagrelor gitandukanye bitewe n'uburwayi bwawe bwihariye n'ibintu bigushyira mu kaga. Abantu benshi bayifata byibuze amezi 12 nyuma yo guhura n'umutima cyangwa indwara ya koroner, nubwo bamwe bayikeneye igihe kirekire.

Umuganga wawe azagenzura buri gihe niba ukwiye gukomeza gufata ticagrelor hashingiwe ku kaga ko kuva amaraso ugereranyije n'ibibazo byo guhura n'ikindi gikorwa cy'umutima. Abantu bamwe barashobora kuyifata imyaka myinshi niba inyungu ziruta ibyago.

Urufatiro rwo gufata icyemezo cyo gukomeza kuvurwa ni umuntu ku giti cye kandi biterwa n'ibintu nk'ubuzima bwawe muri rusange, indi miti urimo gufata, n'uburyo wakiriye ubuvuzi. Umuganga wawe azakuyobora muri uru rugendo rwo gufata icyemezo.

Mbese ni izihe ngaruka ziterwa na Ticagrelor?

Kimwe n'ibindi byose bituma amaraso ataguma, ticagrelor ishobora gutera ingaruka ziterwa n'imiti, nubwo abantu benshi bayihanganira neza. Ingaruka zikunze kugaragara zifitanye isano n'ubushobozi bwayo bwo gutuma amaraso ataguma ndetse n'uko bigira ingaruka ku mikorere isanzwe y'umubiri wawe.

Dore ingaruka ziterwa n'imiti zikunze kugaragara ushobora guhura nazo:

• Kugufiha cyangwa kugorwa no guhumeka
• Gukomereka cyangwa kuva amaraso byoroshye
• Umuvuduko w'amazuru
• Gusohoka kw'amaraso mu ishinya iyo ukora amenyo
• Urubu rw'inda cyangwa isesemi
• Urugero
• Umutwe

Kugufiha ni umwihariko wa ticagrelor kandi bigira ingaruka ku bantu bagera kuri 10-15% bayifata. Ibi mubisanzwe biragenda bikira uko igihe kigenda gihita ariko bishobora kuba biteye impungenge mu ntangiriro.

Abantu bamwe bahura n'ingaruka zikomeye ariko zitagaragara cyane zisaba ubufasha bwihuse bw'abaganga:

• Kuva amaraso menshi atagarara
• Amaraso mu nkari cyangwa mu musarani
• Gukorora amaraso
• Uburibwe bukomeye mu gituza
• Ibimenyetso bya sitiroki (kugabanuka kw'imbaraga mu buryo butunguranye, urujijo, cyangwa impinduka mu iyerekwa)
• Urugero rukomeye rwo kwibasirwa n'umubiri

Izi ngaruka zikomeye ni gake ariko ni ngombwa kuzimenya. Niba ubonye kimwe muri ibi bimenyetso, shakisha ubufasha bw'ubuvuzi ako kanya.

Ninde utagomba gufata Ticagrelor?

Ticagrelor ntabwo itekanye kuri buri wese, kandi muganga wawe azasuzuma neza amateka yawe mbere yo kuyandika. Ibyiciro bimwe na bimwe n'ibihe bituma uyu muti utekanye cyane kuwukoresha.

Ntabwo ugomba gufata ticagrelor niba ufite kimwe muri ibi bikurikira:

• Kuva amaraso mu buryo bukomeye ahantu hose mu mubiri wawe
• Amateka yo kuva amaraso mu bwonko bwawe (intracranial hemorrhage)
• Indwara ikomeye y'umwijima
• Allergie kuri ticagrelor cyangwa ibindi byose bigize

Muganga wawe azitondera cyane mu kwandika ticagrelor niba ufite ibintu bimwe na bimwe byongera ibyago byo kuva amaraso:

• Kubagwa mu gihe gishize cyangwa kubagwa vuba aha
• Amateka y'ibibazo byo mu gifu cyangwa kuva amaraso
• Indwara y'impyiko
• Umubare muto wa platelet
• Gufata izindi miti igabanya amaraso
• Imyaka irenze 75
• Uburemere buke bw'umubiri

Ibi bibazo ntibigutera guhita utemerewe gufata ticagrelor, ariko bisaba gukurikiranwa neza kandi birashoboka ko urugero rw'imiti ruhinduka kugira ngo ugume mu mutekano.

Amazina y'ubwoko bwa Ticagrelor

Ticagrelor ikunze kuboneka ku izina ry'ubwoko rya Brilinta muri Leta Zunze Ubumwe z'Amerika. Iyi ni verisiyo ushobora guhura nayo cyane muri farumasi yawe.

Mu bindi bihugu, ushobora kubona igurishwa ku mazina y'ubwoko atandukanye nka Brilique mu Burayi no mu tundi turere. Hatitawe ku izina ry'ubwoko, ibikoresho bikora n'ingaruka biracyari kimwe.

Verisiyo rusange ya ticagrelor zirimo ziboneka ku isoko zimwe na zimwe, zishobora gutanga amafaranga make mugihe zitanga inyungu zimwe zo kuvura nk'izina ry'ubwoko.

Uburyo bwa Ticagrelor

Niba ticagrelor atagukwiriye, imiti itandukanye igabanya platelet ishobora gutanga uburinzi bumwe bwa cardiovascular. Muganga wawe ashobora gutekereza izi nzira ashingiye ku byo ukeneye byihariye n'amateka yawe y'ubuvuzi.

Clopidogrel (Plavix) ni uburyo busanzwe bwa ticagrelor. Ikora kimwe ikabuza platelet aggregation ariko ifite ingaruka zitandukanye kandi irashobora kwihanganirwa neza nabantu bamwe.

Izindi nzira zirimo prasugrel (Effient), ikindi gihindura P2Y12, cyangwa gukoresha aspirine yonyine kubarwayi bafite ibyago bike. Muganga wawe azagufasha kumenya uburyo butanga uburinganire bwiza bw'ubushobozi n'umutekano kubibazo byawe.

Ese Ticagrelor iruta Clopidogrel?

Ticagrelor yagaragaje ibyiza kurusha clopidogrel mu bushakashatsi bwakozwe, cyane cyane mu kugabanya urupfu ruterwa n'indwara z'umutima, umutima guhagarara gukora, na stroke. Ariko,

Niba wibagiwe gufata urugero rwa ticagrelor, rufate uko wibuka vuba, keretse igihe cyo gufata urugero rukurikira kigeze. Mu gihe nk'icyo, reka urugero wibagiwe urukomeze gahunda yawe isanzwe yo gufata imiti.

Ntuzigere ufata urugero ebyiri icyarimwe kugira ngo usimbure urugero wibagiwe, kuko ibyo byongera ibyago byo kuva amaraso. Niba ukunda kwibagirwa gufata imiti, tekereza gushyiraho ibyibutso kuri terefone cyangwa ukoreshe igikoresho cyo gutegura imiti kugira ngo bigufashe gukurikirana neza.

Ni ryari nshobora kureka gufata Ticagrelor?

Ugomba kureka gufata ticagrelor gusa igihe muganga wawe akubwiye ko byemewe. Guhagarika ako kanya bishobora kongera ibyago byo gupfuka kw'amaraso, kurwara umutima, cyangwa sitiroki, cyane cyane mu mezi make ya mbere nyuma yo gutangira kuvurwa.

Muganga wawe azagabanya buhoro buhoro urugero rwawe cyangwa akuguhe imiti itandukanye igihe kigeze cyo kureka ticagrelor. Icyemezo nk'iki gishingiye ku mpamvu zikureba wowe ubwawe n'igihe umaze ufata umuti.

Nshobora kunywa inzoga niba mfata Ticagrelor?

Ushobora kunywa inzoga rimwe na rimwe niba ufata ticagrelor, ariko kugabanya ni ingenzi. Inzoga ishobora kongera ibyago byo kuva amaraso, cyane cyane iyo ivanze n'imiti ituma amaraso ataguma.

Wishyireho umupaka wo kunywa urugero rumwe ku munsi niba uri umugore cyangwa urugero rwa kabiri ku munsi niba uri umugabo. Niba ufite amateka y'ibibazo by'inzoga cyangwa indwara y'umwijima, ganira na muganga wawe ku bijyanye no kunywa inzoga mbere yo kunywa mu gihe ufata ticagrelor.