Icyo Trihexyphenidyl ari cyo: Ibyo ikoreshwa, urugero rwa dose, ingaruka zayo, n'ibindi

Trihexyphenidyl ni umuti ufasha kugenzura umubumbe w'imitsi n'umutwaro, cyane cyane ku bantu barwaye indwara ya Parkinson cyangwa indwara zo kwimuka ziterwa n'imiti imwe na rimwe ya psychiatric. Tekereza nk'umufasha ukorera mu bwonko bwawe kugira ngo asubize uburinganire iyo sisitemu yawe yo kugenzura imyitozo ihungabanye.

Uyu muti ufitanye isano n'itsinda ryitwa anticholinergics, bivuze ko ibuza ibimenyetso bimwe na bimwe bya chimique mu bwonko bwawe bishobora gutera imitsi idashakishwa. Mugihe imaze imyaka myinshi kandi yafashije abantu benshi gusubirana imyitozo yoroshye, ni ngombwa kumva uko ikora n'icyo wakwitega.

Trihexyphenidyl ni iki?

Trihexyphenidyl ni umuti unyobwa mu kanwa uza mu buryo bwa tablet kandi ukora ubuza acetylcholine, intumwa ya chimique mu bwonko bwawe. Iyo acetylcholine iba irenga ugereranije n'indi chimique yo mu bwonko yitwa dopamine, irashobora gutera umubumbe w'imitsi, umutwaro, n'ibindi bibazo byo kwimuka.

Mugihe ubuza bimwe muri ibi bimenyetso bya acetylcholine, trihexyphenidyl ifasha gusubiza uburinganire bwa chimique mu bwonko bwawe. Ibi bisubiza uburinganire bituma imitsi yawe iruhuka kandi imyitozo yawe ikaba yoroshye kandi igenzurwa.

Uyu muti uboneka muri tablet zihita zikora vuba na capsules zirekura igihe kirekire zitanga ingaruka zirambye umunsi wose. Muganga wawe azahitamo uburyo bukwiye bushingiye ku byo ukeneye byihariye n'imiterere y'ibimenyetso.

Trihexyphenidyl ikoreshwa kubera iki?

Trihexyphenidyl ikoreshwa cyane cyane mu kuvura indwara zo kwimuka zibaho iyo uburinganire bwa chimique bwo mu bwonko bwawe buhungabanye. Ikoreshwa cyane cyane mu gukemura ibimenyetso bya indwara ya Parkinson n'ibibazo byo kwimuka biterwa n'imiti.

Uyu muti ufasha mu bibazo bitandukanye bigira ingaruka ku bushobozi bwawe bwo kwimuka bisanzwe:

• Umutingito wa indwara ya Parkinson n'ubugoye bw'imitsi
• Indwara ya parkinson iterwa n'imiti ivura indwara zo mu mutwe
• Dystonia ikaze (imitsi ihita yikubita cyane)
• Tardive dyskinesia mu bihe bimwe na bimwe
• Parkinson nyuma yo kurwara encefalite

Abantu benshi babona ko bifasha cyane mu kugabanya umutingito wo "gukubita ibinini" usanzwe mu ndwara ya Parkinson n'ubugoye bw'imitsi bushobora gutuma imirimo ya buri munsi igorana. Irashobora kandi gufasha mu kuruka no mu ngorane zimwe na zimwe zo kuvuga zijyanye n'ibi bibazo.

Mu bihe bidasanzwe, abaganga bashobora kwandikira trihexyphenidyl kubera izindi ndwara z'imitsi nka indwara ya Wilson cyangwa ubwoko bumwe na bumwe bwa dystonia, nubwo izi nshingano zitamenyerewe kandi zisaba ubugenzuzi bwihariye bw'abaganga.

Trihexyphenidyl ikora ite?

Trihexyphenidyl ikora ibyara ibice bya acetylcholine mu bwonko bwawe, cyane cyane mu turere tuyobora imitsi. Uyu muti ufatwa nk'ukomeye cyane mu miti ivura indwara z'imitsi, bivuze ko ushobora kugira akamaro kanini ariko bisaba gukurikiranwa neza.

Mu bwonko buzima, acetylcholine na dopamine bikorana nk'ababyinnyi kugira ngo bahuze imitsi yoroshye. Iyo urwego rwa dopamine rugabanutse (nk'uko bimeze mu ndwara ya Parkinson) cyangwa iyo imiti imwe na imwe ibuza dopamine, acetylcholine iba iyobora kandi itera ibibazo nk'umutingito n'ubugoye.

Mugukingira ibikorwa bya acetylcholine, trihexyphenidyl ifasha kugarura iyi garuriro ryoroshye. Uyu muti ubusanzwe utangira gukora mu isaha imwe cyangwa ebyiri nyuma yo kuwufata, ibyiza byawo bikamara amasaha agera kuri 6-12 bitewe niba urimo gufata ubwoko butangira ako kanya cyangwa ubwoko butinda.

Ni ngombwa gusobanukirwa ko trihexyphenidyl idakiza indwara yihishe ahubwo igenzura ibimenyetso byongera imiterere ya chimique mu bwonko bwawe. Ibi nibyo bituma gukoresha buri munsi bisanzwe bikenewe kugira ngo bigumane kugenzura ibimenyetso.

Nkwiriye gufata trihexyphenidyl nte?

Fata trihexyphenidyl uko umuganga wawe abikwandikiye, akenshi utangira n'urugero ruto rugenda ruzamuka buhoro buhoro uko igihe kigenda gihita. Abantu benshi babifata inshuro 3-4 ku munsi bafata ibinini byihuta cyangwa inshuro 1-2 ku munsi bafata ibinini bifata igihe kinini.

Urashobora gufata uyu muti urya cyangwa utarya, ariko kuwufata urya birashobora kugufasha kugabanya kuribwa mu gifu niba wumva ubifite. Niba uhisemo kuwufata urya, gerageza kujya ubikora ku gihe kugira ngo ugumane urugero ruhamye mu mubiri wawe.

Dore inama zimwe z'ingirakamaro zo gufata trihexyphenidyl mu buryo bwizewe:

• Fata ku gihe kimwe buri munsi kugira ngo ugumane kugenzura ibimenyetso bihamye
• Tangira n'urugero ruto rukora neza kandi wongere buhoro buhoro nk'uko byategetswe
• Ntugasenye cyangwa urume ibinini bifata igihe kinini
• Guma mu murongo uhamye kugira ngo wibuke imiti yawe
• Guma ufite amazi ahagije, kuko umuti ushobora gutera umunwa wumye

Ntuzigere uhagarika gufata trihexyphenidyl ako kanya, kuko ibi bishobora gutera ibimenyetso byo kuva mu miti no kugaruka kw'ibibazo byawe byo kugenda. Jya ukorana n'umuganga wawe buri gihe kugira ngo ugabanye buhoro buhoro urugero niba ukeneye guhagarika umuti.

Nzagufata Trihexyphenidyl Igihe Kingana Gite?

Igihe cyo kuvura na trihexyphenidyl gitandukanye cyane bitewe n'uburwayi bwawe bw'ibanze n'uburyo umubiri wawe witwara. Abantu bamwe barabukeneye mu mezi make, mu gihe abandi basaba kuvurwa igihe kirekire imyaka myinshi.

Ku bibazo byo kugenda biterwa n'imiti, ushobora gukenera trihexyphenidyl by'agateganyo mu gihe umubiri wawe wimenyereza imiti ya psychiatrie cyangwa mu gihe iyo miti ihindurwa. Muri ibi bihe, kuvurwa bishobora kumara icyumweru kimwe kugeza ku mezi make.

Ku ndwara ya Parkinson cyangwa izindi ndwara zidakira zo kugenda, trihexyphenidyl akenshi ni uburyo bwo kuvura igihe kirekire uzajya ufata imyaka myinshi. Umuganga wawe azajya asuzuma buri gihe niba inyungu zigikomeza kurusha ingaruka zose kandi ashobora guhindura urugero rwawe cyangwa agatekereza ku zindi nzira uko igihe kigenda gihita.

Abantu bamwe basanga imiti itagikora neza uko iminsi igenda, iki kintu kikaba cyitwa kwihanganira. Iyo ibi bibaye, muganga wawe ashobora kugabanya urugero rw'umuti by'agateganyo, akaguherereza undi muti, cyangwa akongerera izindi nshingano mu buvuzi bwawe.

Ni Ibihe Bikorwa Bigaragara bya Trihexyphenidyl?

Kimwe n'imiti yose, trihexyphenidyl ishobora gutera ibikorwa bigaragara, nubwo atari buri wese ubyumva. Ibikorwa bigaragara cyane bifitanye isano n'imikorere yayo ya anticholinergic kandi akenshi biba byoroheje cyangwa bikaba hagati.

Ibikorwa bisanzwe bigaragara abantu benshi bashobora kwifashisha birimo:

• Umunwa wumye (cyane)
• Kureba nabi cyangwa kugorwa no kureba neza
• Kugorwa kwituma
• Gusinzira cyangwa kuribwa umutwe
• Isesemi cyangwa kuribwa mu nda
• Kugorwa kunyara
• Urujijo cyangwa ibibazo byo kwibuka, cyane cyane ku bantu bakuze

Ibikorwa byinshi bigaragara birushaho gukira uko umubiri wawe wimenyereza umuti cyangwa bishobora guhangana n'ingamba zoroshye nko kuguma mu mazi, gukoresha amarira y'ubwenge, cyangwa kurya ibiryo birimo fibre nyinshi.

Ibikorwa bikomeye bigaragara ntibisanzwe ariko bisaba ubufasha bwihuse bw'abaganga. Ibi birimo urujijo rukabije, kwibeshya, umutima utera cyane, kugorwa cyane kwituma, kutabasha kunyara, cyangwa ibimenyetso byo gushya (kuva umuti ushobora kugira ingaruka ku bushobozi bw'umubiri wawe bwo kugenzura ubushyuhe).

Ibikorwa bidakunze kugaragara ariko bishobora kuba bikomeye birimo glaucoma yo gufunga impande, ibikorwa bikabije byo kwibasirwa n'umubiri, cyangwa impinduka zikomeye mu mutima. Niba wumva ububabare mu gituza, kugorwa cyane guhumeka, cyangwa impinduka zidasanzwe mu kureba, shakisha ubufasha bw'abaganga ako kanya.

Ni Bande Batagomba Gufata Trihexyphenidyl?

Abantu bamwe bagomba kwirinda trihexyphenidyl kubera kwiyongera kw'ibibazo bikomeye. Muganga wawe azasuzuma neza amateka yawe mbere yo kwandika uyu muti.

Ntabwo ugomba gufata trihexyphenidyl niba ufite:

• Glokoma y'amaso afunganye
• Ulcerative colitis ikaze
• Myasthenia gravis
• Indwara ikaze y'impyiko cyangwa umwijima
• Urubavu rwagutse rutera ibibazo byo kunyara
• Allergie izwi kuri trihexyphenidyl cyangwa imiti isa nayo

Ubushishozi bwihariye bukenewe ku bantu bakuze, kuko bafite ubworoherane bwinshi ku ngaruka ziterwa na anticholinergic nk'urujijo, ibibazo byo kwibuka, no kugwa. Abantu bafite indwara z'umutima, glokoma yoroheje, cyangwa urubavu rworoshye rwagutse barashobora gufata umuti ariko bakeneye gukurikiranwa hafi.

Niba utwite cyangwa wonka, ganira ku byago n'inyungu na muganga wawe, kuko umutekano wa trihexyphenidyl mugihe cyo gutwita utarashyirwaho neza. Uyu muti ushobora kujya mu mata y'ibere kandi ugashobora kugira ingaruka ku mwana wonka.

Amazina y'ubwoko bwa Trihexyphenidyl

Trihexyphenidyl iboneka munsi y'amazina menshi y'ubwoko, nubwo verisiyo rusange ikoreshwa cyane. Izina rizwi cyane ni Artane, ryabonetse mumyaka myinshi.

Andi mazina y'ubwoko arimo Apo-Trihex, Trihexane, na formulations zitandukanye rusange ziva kubakora batandukanye. Ubwoko bwose burimo ibintu bikora kimwe kandi bikora kimwe, nubwo abantu bamwe bashobora kubona itandukaniro rito mukuntu banywa vuba cyangwa igihe bamaraho.

Farumasi yawe irashobora gusimbuza verisiyo zitandukanye rusange keretse muganga wawe yerekanye ubwoko bwihariye. Niba ubonye impinduka iyo arizo zose mukuntu umuti ukora mugihe uhindura hagati yubwoko, menyesha muganga wawe kugirango bashobore gukora impinduka zikenewe.

Uburyo bwo gusimbuza Trihexyphenidyl

Uburyo bwinshi bwo gusimbuza trihexyphenidyl burahari mugukiza indwara zigenda, buri kimwe gifite inyungu zacyo n'ibitekerezo. Muganga wawe ashobora gutanga ibisubizo niba trihexyphenidyl itagukorera neza cyangwa itera ingaruka ziteye isoni.

Izindi imiti ya anticholinergic zirimo benztropine (Cogentin) na biperiden, bikora kimwe ariko bishobora kugira ingaruka zitandukanye. Abantu bamwe babyihanganira kurusha abandi, bityo guhinduranya hagati yabo birashobora gufasha.

Kubijyanye na Parkinson's disease by'umwihariko, izindi mpinduka zirimo:

• Carbidopa-levodopa (igipimo cyiza cyo kuvura indwara ya Parkinson)
• Dopamine agonists nka pramipexole cyangwa ropinirole
• MAO-B inhibitors nka rasagiline cyangwa selegiline
• COMT inhibitors nka entacapone
• Amantadine yo kugenzura umutwaro

Kubijyanye n'indwara ziterwa n'imiti, izindi mpinduka zirimo kugabanya urugero rw'umuti utera ikibazo, guhindurira ku wundi muti wa psychiatrique, cyangwa gukoresha izindi miti ivura indwara z'umutwaro nka tetrabenazine cyangwa deutetrabenazine.

Ese Trihexyphenidyl iruta Benztropine?

Trihexyphenidyl na benztropine ni imiti ya anticholinergic ikora neza, ariko ifite itandukaniro rikomeye rituma imwe ishobora kuba nziza kurusha iyindi kubantu bamwe. Guhitamo hagati yabo biterwa n'ibimenyetso byawe byihariye, kwihanganira ingaruka, n'ubuzima bwawe.

Trihexyphenidyl akenshi ifatwa nk'ikora neza mu kugenzura umutwaro kandi ishobora gukora neza kubantu bafite ibimenyetso by'umutwaro. Iraboneka kandi mu buryo bwo gukoreshwa igihe kirekire, bishobora korohereza abantu bamwe bakunda gukoresha imiti kenshi.

Benztropine, ku rundi ruhande, ishobora gutera urujijo ruto n'ibibazo byo kwibuka mu bantu bakuze kandi iraboneka nk'urushinge rwo kuvura ibibazo by'umutwaro byihutirwa. Nanone ikunda gutera umunwa wumye muke kubantu bamwe.

Muganga wawe azatekereza ibintu nk'imyaka yawe, izindi ndwara, izindi miti urimo gufata, n'ibimenyetso byawe byihariye mugihe uhitamo hagati y'izi mpinduka. Abantu bamwe bashobora no kugerageza zombi kugirango barebe niba ari iyihe ikora neza kubibazo byabo byihariye.

Ibibazo Bikunze Kubazwa Kuri Trihexyphenidyl

Q1. Ese Trihexyphenidyl Ifite Umutekano Ku Ndwara Z'umutima?

Trihexyphenidyl irashobora gukoreshwa ku bantu barwaye indwara z'umutima, ariko bisaba gukurikiranwa neza no guhindura urugero rw'umuti. Rimwe na rimwe uyu muti ushobora gutera impinduka mu mikorere y'umutima cyangwa ukongera umuvuduko w'umutima, bityo muganga wawe azagomba gupima inyungu zayo n'ibishobora kuba byateza.

Niba urwaye indwara y'umutima, muganga wawe ashobora gutangira urugero ruto hanyuma akagenzura imikorere y'umutima wawe neza. Ashobora kandi kugusaba gupima umuvuduko w'umutima buri gihe, cyane cyane iyo utangiye gufata umuti cyangwa wiyongera urugero rwawo.

Abantu bafite indwara z'umutima zimwe na zimwe nko kunanirwa gukora cyane k'umutima cyangwa imikorere mibi y'umutima ishobora kuba ngombwa ko birinda rwose trihexyphenidyl cyangwa bakayikoresha ari uko babanje kugisha inama umuganga. Buri gihe menyesha muganga wawe ibibazo byose by'umutima mbere yo gutangira uyu muti.

Q2. Nzakora iki niba nanyoye cyane Trihexyphenidyl ku buryo butunguranye?

Niba unyoye cyane trihexyphenidyl ku buryo butunguranye, vugana n'umuganga wawe cyangwa ikigo gishinzwe kurwanya ubumara ako kanya, kabone n'iyo wumva umeze neza. Kunywa umuti mwinshi bishobora gutera ibimenyetso bikomeye bishobora kutagaragara ako kanya.

Ibimenyetso byo kunywa cyane trihexyphenidyl birimo urujijo rukomeye, kwibeshya, umutima utera cyane, guhumeka bigoye, umunwa wumye cyane, kutabasha kunyara, umuriro mwinshi, cyangwa kutagira ubwenge. Ibi bimenyetso bisaba ubufasha bwihutirwa bw'abaganga.

Mugihe utegereje ubufasha bw'abaganga, guma utuje kandi ntugerageze kwivugisha niba utabitegetswe n'abaganga. Guma ufite icupa ry'umuti kugirango werekane neza abaganga icyo wanyoye n'urugero rwawo.

Kugirango wirinde kunywa umuti mwinshi ku buryo butunguranye, tekereza gukoresha agasanduku k'imiti, gushyiraho alarme kuri terefone, cyangwa gusaba abagize umuryango kugufasha gukurikirana gahunda yawe yo kunywa imiti.

Q3. Nzakora iki niba nirengagije urugero rwa Trihexyphenidyl?

Niba wibagiwe gufata urugero rwa trihexyphenidyl, urufate ako kanya wibukiye, keretse igihe cyo gufata urugero rukurikira cyegereje. Ntukigere ufata urugero rurenze rumwe icyarimwe kugira ngo usimbure urugero wibagiwe, kuko ibyo bishobora kongera ibyago byo kugira ingaruka zidakurikije.

Niba urimo gufata ibinini bifatika ako kanya kandi hashize amasaha arenga 2-3 uhereye ku rugero wibagiwe, ushobora kubireka ugategereza urugero rwawe rukurikira. Ku bikoresho bifata igihe kirekire, icyo gihe kiraguka, ariko ntukagire urugero wibagiwe niba bitarenze amasaha 6 uhereye ku rugero rwawe rukurikira.

Kutagira urugero rimwe na rimwe mubisanzwe ntibizatera ibibazo bikomeye, ariko ushobora kubona ko ibimenyetso byo kugenda byagarutse by'igihe gito. Niba ukunda kwibagirwa urugero, tekereza gushyiraho ibyibutsa kuri terefone cyangwa gukoresha umuteguro w'ibinini kugira ngo bifashe mu kugumana urugero rw'imiti ihamye.

Q4. Ni ryari nshobora kureka gufata Trihexyphenidyl?

Ugomba kureka gufata trihexyphenidyl gusa ukurikije ubuyobozi bwa muganga wawe, kuko guhagarika ako kanya bishobora gutera ibimenyetso byo gukurwaho no kugaruka vuba kw'ibibazo byawe byo kugenda. Umwanzuro wo guhagarika biterwa n'uburwayi bwawe bw'ibanze n'uburyo urimo gusubiza mu buryo bwiza ku buvuzi.

Ku bibazo by'igihe gito nk'indwara zo kugenda ziterwa n'imiti, ushobora kureka trihexyphenidyl igihe icyateye ikibazo cyakemutse. Muganga wawe azagabanya urugero buhoro buhoro mu byumweru byinshi kugira ngo yirinde ibimenyetso byo gukurwaho.

Ku bibazo bihoraho nk'indwara ya Parkinson, kureka trihexyphenidyl bishobora gutekerezwa niba ingaruka zidakurikije zibaye ibibazo cyangwa niba izindi mvura zigaragaza neza. Ariko, abantu benshi bakomeza kuyifata igihe kirekire nk'igice cy'umugambi wabo wose wo kuvura.

Ibimenyetso bisanzwe byo gukurwaho birimo guhangayika, kutagira ibitotsi, isesemi, no kugaruka vuba kw'ibimenyetso byo kugenda. Ibi bishobora kugabanuka mugihe urugero rugabanuka buhoro buhoro ukurikije ubuyobozi bwa muganga aho guhagarara ako kanya.

Q5. Nshobora kunywa inzoga niba ndimo gufata Trihexyphenidyl?

Ni byiza kwirinda inzoga cyangwa kuzigabanya cyane mugihe ufata trihexyphenidyl, kuko ibyo bintu byombi bishobora gutera gusinzira, urujijo, no kugira ibibazo byo guhuza ibintu. Iyo byahujwe, ibyo byose bishobora guteza akaga kandi bikongera ibyago byo kugwa cyangwa impanuka.

Inzoga kandi irashobora gukomeza ibibazo byinshi byo kuruhande rwa trihexyphenidyl, harimo umunwa wumye, guhagarara kw'amara, no kugorana kunyara. Uko guhuza ibintu bishobora no kubangamira imitekerereze yawe n'urwibutso kurusha ikindi kintu cyose cyonyine.

Niba uhisemo kunywa inzoga rimwe na rimwe, tangira n'utuntu duto cyane kugirango urebe uko umubiri wawe witwara, kandi ntuzigere unywa inzoga ugatwara imodoka cyangwa ukoresha imashini. Buri gihe ganira ku kunywa inzoga na muganga wawe, kuko bashobora gutanga inama zihariye zishingiye ku miterere yawe yihariye n'indi miti urimo gufata.