Icyo Urofollitropin ari cyo: Ibyo ikoreshwa, urugero rwo kuyifata, ingaruka zayo n'ibindi

Urofollitropin ni umuti ufasha kubyara urimo umusemburo wa follicle-stimulating (FSH), umusemburo w'umubiri wawe ukora kugira ngo ufashishe mu gukura kw'amagigi mu bagore na sperme mu bagabo. Uyu muti ukurwa mu nkari z'abagore bamaze guca imbyaro kandi ukarurwa kugira ngo ukore umuti ushobora gufasha abashakanye bahura n'ingorane zo kubyara.

Niba uhanganye n'ibibazo byo kubyara, ntabwo uri wenyine, kandi hari imiti ikora neza iboneka. Urofollitropin ikora yigana ibimenyetso by'umusemburo w'umubiri wawe, ihereza urugingo rwawe rw'imyororokere ubufasha bwongereye bushobora kuba bukenewe kugira ngo rukore neza.

Urofollitropin ikoreshwa mu iki?

Urofollitropin ifasha abagore bafite ibibazo byo gutera urugimbi cyangwa gukora amagi akomeye. Muganga wawe ashobora kugusaba uyu muti niba intanga ngore zawe zikeneye imbaraga zidasanzwe kugira ngo zirekure amagi mugihe cyo kuvurwa kugira ngo ubone urubyaro nka in vitro fertilization (IVF) cyangwa intrauterine insemination (IUI).

Ku bagore, uyu muti ni ingirakamaro cyane iyo ufite indwara nka polycystic ovary syndrome (PCOS), hypothalamic amenorrhea, cyangwa izindi mpinduka za hormone zigira ingaruka ku mikurire y'igi. Ikoreshwa kandi iyo uri gukoresha ikoranabuhanga ryo gufasha kubyara aho hakenewe amagi menshi.

Mu bagabo, urofollitropin ishobora gufasha kongera umubare wa sperme iyo umubare muto wa sperme uterwa n'ubuke bwa hormone. Muganga wawe azemeza niba ubu buvuzi bukugirira akamaro nyuma yo gupimwa no gusuzumwa neza.

Urofollitropin ikora ite?

Urofollitropin ikora itanga mu buryo butaziguye umubiri wawe na FSH, umusemburo ushinzwe gutera intanga ngore zawe gukura no gukomera. Tekereza nk'uko uha urugingo rwawe rw'imyororokere ikimenyetso cyihariye rukeneye kugira ngo ibintu bitangire kugenda.

Uyu muti ufatwa nk'umuti wo kuvura ububabare bwo mu rugero rwo hagati. Ufite imbaraga kurusha imiti yo mu kanwa ivura ububabare nk'iyo bita clomiphene ariko ntugoye nk'andi ma hormone aterwa mu nshinge. FSH iri muri urofollitropin ifatana n'uturemangingo two mu ntanga z'abagore, bigatuma imitsi ikura irimo amagi yawe.

Iyo imitsi ikuze, itanga estrogen, itegurira urukuta rw'inda yawe gutwita. Muganga wawe azakurikirana iki gikorwa neza akoresheje ibizamini by'amaraso na ultrasounds kugira ngo arebe niba umuti ukora neza kandi mu buryo butekanye.

Nkwiriye Gufata Urofollitropin Nte?

Urofollitropin itangwa mu nshinge haba munsi y'uruhu rwawe (subcutaneous) cyangwa mu mutsi wawe (intramuscular). Muganga wawe azakwigisha cyangwa azigisha uwo mwashakanye uburyo bwo kwitera izi nshinge mu rugo mu buryo butekanye, cyangwa ushobora kuzihabwa ku biro bya muganga wawe.

Igihe cyo kwitera inshinge ni ingenzi kugira ngo bigende neza. Ubusanzwe utangira gufata urofollitropin ku minsi runaka y'imihango yawe, akenshi hagati y'iminsi 2-5, nk'uko byategetswe na muganga wawe w'inzobere mu kubyara. Igihe nyacyo giterwa n'uburyo bwo kuvurwa bwihariye.

Ntabwo ukeneye gufata uyu muti hamwe n'ibiryo kuko uterwa mu nshinge, ariko ni ngombwa kuwufata ku gihe kimwe buri munsi. Bika amacupa atarafungurwa muri firigo hanyuma uyareke agere ku bushyuhe busanzwe mbere yo kwitera kugira ngo ugabanye kutamererwa neza.

Muganga wawe azatanga amabwiriza arambuye ku bijyanye no guhinduranya aho utera inshinge kugira ngo wirinde kwangirika. Ahantu hasanzwe haterwa inshinge harimo ikibero cyawe, inda, cyangwa ukuboko kwawe kw'igice cyo hejuru. Jya ukoresha urushinge rushya, rutariho mikorobe buri gihe kandi ujye ujugunya inshinge zakoreshejwe neza mu kintu cyagenewe kujugunyirizwamo ibikoresho byose bityaye.

Nkwiriye Gufata Urofollitropin Igihe Kingana Gite?

Abagore benshi bafata urofollitropin iminsi 7-14 muri buri gihe cyo kuvurwa. Muganga wawe azakurikirana uko witwara akoresheje ibizamini by'amaraso bisanzwe na ultrasounds kugira ngo amenye igihe nyacyo gikwiriye kuri wowe.

Ubukure bw'imiti buterwa n'uko imitsi yawe ikura vuba ikagera ku bunini bukwiye. Abagore bamwe basubiza vuba mu cyumweru, mu gihe abandi bashobora gukenera iminsi igera kuri ibiri yo guterwa inshinge buri munsi. Umuganga wawe w'inzobere mu bijyanye n'uburumbuke azahindura gahunda yawe yo kuvurwa bitewe n'uko wowe ubwawe ubyitwaramo.

Ushobora gukenera gukoresha imiti inshuro nyinshi kugira ngo ugere ku gutwita. Abashakanye benshi bakenera gukoresha imiti hagati y'inshuro 3-6, nubwo ibi bitandukana cyane ku muntu ku giti cye. Muganga wawe azaganira ku byiringiro by'ukuri n'igihe bizatwara bitewe n'icyo wagaragaje cy'uburumbuke.

Ni Ibihe Bikorwa Bigaragara Biterwa n'Urufollitropin?

Kimwe n'indi miti yose, urufollitropin rushobora gutera ibikorwa bigaragara, nubwo atari buri wese ubyumva. Ibikorwa bigaragara byinshi ni bike kandi birashoboka kubicunga, kandi ikipe yawe y'ubuvuzi izagukurikiranira hafi mu gihe uvurwa.

Ibikorwa bigaragara cyane ushobora guhura nabyo birimo kutumva neza ahaterwa urushinge, nk'ubutukura, kubyimba, cyangwa kumva ububabare. Ibi mubisanzwe birakira mu masaha make kandi birashobora kugabanuka mugihe uhinduranya ahaterwa urushinge no gushyiraho urubura mbere yo guterwa urushinge.

Dore ibikorwa bigaragara bikunze kugaragara ugomba kumenya:

• Umutwe n'umunaniro muke
• Kubyimba no kutumva neza mu nda
• Urubavu rw'amabere
• Guhinduka kw'amarangamutima cyangwa kumva ibintu cyane
• Isesemi cyangwa guhungabana gake mu gifu
• Gushyuha cyane cyangwa ibyuya by'ijoro

Ibi bimenyetso akenshi bisa n'ibimenyetso byo mu ntangiriro zo gutwita cyangwa PMS ikaze, bishobora kuba imbogamizi mu gihe cyo kuvurwa uburumbuke. Wibuke ko guhura n'ibi bikorwa bigaragara ntibisobanura intsinzi cyangwa kunanirwa kw'imiti yawe.

Ibikorwa bigaragara bikomeye ariko bidakunze kugaragara bisaba ubufasha bw'ubuvuzi bwihutirwa. Izi ngorane zitabaho cyane zirimo indwara ya ovarian hyperstimulation syndrome (OHSS), aho imitsi yawe iba minini cyane kandi ikabyara amagi menshi cyane.

Vugana n'umuganga wawe ako kanya niba ubonye:

• Uburibwe bukomeye mu nda cyangwa kubyimba
• Ubwiyongere bw'ibiro bwihuse (birenze ibiro 0.9 ku munsi)
• Kugorwa no guhumeka cyangwa guhumeka bigufi
• Isesemi ikabije no kuruka
• Kugabanuka kw'inkari
• Uburibwe bukomeye bwo mu mutwe buherekejwe n'imihindagurikire mu iyerekwa

Ibi bimenyetso bishobora kwerekana OHSS cyangwa izindi ngorane zikomeye zikeneye ubuvuzi bwihuse. Ivuriro ryawe ry'ubuzima bw'imyororokere rizagutegurira amabwiriza yihariye yo kumenya igihe ugomba kubahamagara ako kanya.

Ninde utagomba gufata Urofollitropin?

Urofollitropin ntibereye buri wese, kandi muganga wawe azasuzuma neza amateka yawe y'ubuzima mbere yo kuyandika. Ibyiciro bimwe na bimwe bituma uyu muti utaba mwiza cyangwa utagira akamaro.

Ntabwo ugomba gufata urofollitropin niba usanzwe utwite cyangwa wonsa. Muganga wawe azemeza ko utatwite mbere yo gutangira kuvurwa kandi ashobora kugusaba ibizamini byo kumenya niba utwite mu gihe cyose cy'imihango yawe.

Ibyiciro byinshi by'ubuzima bituma urofollitropin idakwiriye cyangwa iteje akaga:

• Utubyimba tw'intanga ngore cyangwa intanga ngore zabyimbye (keretse bitewe na PCOS)
• Gusohoka amaraso mu gitsina bitasobanutse
• Indwara z'umukororombya cyangwa adrenal zitagenzurwa neza
• Ibimeme by'intanga ngore, ibere, nyababyeyi, hypothalamus, cyangwa glande ya pituitary
• Kunanirwa kw'intanga ngore (igihe intanga ngore zahagaze gukora burundu)
• Indwara zikomeye z'impyiko cyangwa umwijima

Niba ufite amateka y'amaraso yiziba, sitiroki, cyangwa indwara y'umutima, muganga wawe azagereranya ibyago n'inyungu neza. Abagore bamwe bafite ibi byiciro barashobora gukoresha urofollitropin bakurikiranwa n'abaganga.

Imyaka yawe nayo ishobora kugira uruhare niba uyu muti ukwiriye. Nubwo nta myaka ntarengwa, urwego rw'intsinzi rukunda kugabanuka cyane nyuma y'imyaka 42, kandi ibyago birashobora kwiyongera.

Amazina y'ubwoko bwa Urofollitropin

Urofollitropin iboneka mu mazina menshi y'ubucuruzi, nubwo ikintu gikora kigumaho kimwe. Izina rikoreshwa cyane ni Bravelle, ryakoreshejwe cyane mu kuvura uburumbuke mu myaka myinshi.

Andi mazina y'ubucuruzi arimo Fertinex, nubwo iyi formulation yihariye yahagaritswe ku masoko amwe. Farumasi yawe ishobora kugira verisiyo rusange ya urofollitropin, irimo hormone imwe ikora ariko ishobora kuba ihendutse.

Verisiyo y'ubucuruzi cyangwa rusange wakira ntigira ingaruka zikomeye ku mikorere y'umuti. Ariko, ni ngombwa gukoresha ubwoko bumwe buri gihe mu gihe cyo kuvurwa kwawe kugirango wemeze ko imiti ikoreshwa neza kandi igire icyo igeraho.

Izindi miti isimbura Urofollitropin

Imiti myinshi isimbura irashobora gushishikariza ovulation niba urofollitropin atari yo ikwiriye kuri wewe. Muganga wawe ashobora gushimangira imiti ya recombinant FSH nka Gonal-F cyangwa Follistim, izo zikaba ari verisiyo za sintetike za hormone imwe.

Izi nzira za sintetike akenshi zitera ibimenyetso byinshi byo kwibasirwa n'umubiri kuko zitava mu nkari z'abantu. Ziza kandi mu bikoresho byoroshye bya peni abantu bamwe basanga byoroshye gukoresha kurusha ibikoresho bisanzwe na sirinji.

Kubuvuzi butagoye cyane, muganga wawe ashobora gutanga igitekerezo cyo gutangira imiti yo kunywa nk'umuti wa clomiphene citrate (Clomid) cyangwa letrozole (Femara). Izi pilule biroroshye gufata kandi bihendutse, nubwo bishobora kutagira akamaro ku bagore bakeneye gushishikarizwa cyane kwa ovarian.

Human menopausal gonadotropin (hMG) ni indi nzira y'inkingo irimo FSH na luteinizing hormone (LH). Imiti nka Menopur cyangwa Repronex ishobora kuba ikwiriye niba ukeneye hormone zombi kugirango ugire icyo ugeraho.

Ese Urofollitropin iruta Clomiphene?

Urofollitropin na clomiphene bikora mu buryo butandukanye kandi bikwiriye kubibazo bitandukanye. Clomiphene ni uburyo bwo kuvura bwa mbere kuko ifatwa mu kanwa kandi ntigira ingaruka nyinshi kurusha inkingo.

Urofollitropin akenshi ikora neza kurusha clomiphene ku bagore batitabiriye imiti yo kunywa cyangwa bakeneye kugenzura neza uburyo bwo guteza imbere imikorere y'intanga ngore. Ni nziza cyane cyane ku byiciro bya IVF aho amagi menshi akenewe.

Ariko, "gukora neza" biterwa n'uko ubuzima bwawe bumeze. Clomiphene irashobora kuba ikwiriye neza niba ugitangira kuvurwa indwara zo kubura urubyaro kandi ufite ibibazo byoroheje byo kororoka. Iragura kandi ku buryo bugaragara kandi ntisaba inshinge za buri munsi.

Muganga wawe akenshi azagerageza clomiphene mbere na mbere keretse niba ufite ibibazo byihariye bituma urofollitropin iba nziza mbere na mbere. Icyemezo giterwa n'ibintu nk'imyaka yawe, icyo barwaye, amateka y'imiti wanyuzeho mbere, n'ubwishingizi.

Ibikunze Kubazwa Kuri Urofollitropin

Ese Urofollitropin irakwiriye ku bagore bafite PCOS?

Yego, urofollitropin irashobora kuba nziza kandi ikora neza ku bagore bafite PCOS, ariko bisaba gukurikiranwa neza. Abagore bafite PCOS bafite ibyago byinshi byo kurwara indwara ya ovarian hyperstimulation syndrome (OHSS) kuko intanga ngore zabo zikunda kwitabira cyane imiti yo kubyara.

Muganga wawe ashobora gutangira n'urugero ruto kandi akagukurikiranira hafi cyane hamwe n'ibizamini by'amaraso na ultrasounds. Intego ni ugushishikariza intanga ngore zawe bihagije kugirango zikore amagi yuzuye neza hatabayeho gushishikariza cyane.

Abagore benshi bafite PCOS bagera ku nda nziza bakoresheje urofollitropin, cyane cyane iyo imiti yo kunywa yabanje gukoreshwa itagize icyo ikora. Umuganga wawe wihariye mu by'ubuzima azakora gahunda yihariye igabanya ibyago mugihe yongera amahirwe yawe yo gusama.

Nigute nakora niba nifuje gukoresha urofollitropin nyinshi?

Niba wifuje kwitera urofollitropin nyinshi, vugana na clinique yawe y'ubuzima bw'uburumbuke ako kanya, kabone niyo byaba nyuma y'amasaha y'akazi. Amavuriro menshi afite serivisi zihari zishinzwe ibibazo by'imiti nk'ibi.

Kurenza umuti bishobora kongera ibyago byo kurwara indwara ya ovarian hyperstimulation syndrome, bityo muganga wawe azashaka kugukurikiranira hafi akoresheje ibizamini by'amaraso na ultrasounds. Bashobora guhindura imiti isigaye cyangwa guhagarika imiti by'agateganyo bitewe n'umuti w'inyongera wahawe.

Ntugahagarike umutima niba ibi bibaye - amakosa yo gutanga imiti abaho kenshi kuruta uko wabitekereza, kandi ikipe yawe y'abaganga ifite ubunararibonye mu gucunga ibi bihe. Vuga ukuri ku buryo nyabwo wanyoye imiti y'inyongera kugira ngo batange ubuvuzi bwiza.

Nkwiriye gukora iki niba nciwe urugero rwa Urofollitropin?

Niba waciwe urugero rwa urofollitropin, vugana na clinique yawe y'ubuzima bw'imyororokere vuba bishoboka kugira ngo ubone ubuyobozi. Igihe cyo gufata imiti y'ubuzima bw'imyororokere ni ingenzi, bityo ntugerageze gufata icyemezo wenyine niba ufata urugero rutinze.

Muri rusange, niba wibuka mu masaha make nyuma y'igihe cyagenwe cyo guterwa urushinge, muganga wawe ashobora kukubwira gufata urugero rwaciwe ako kanya. Ariko, niba hashize amasaha menshi cyangwa hafi y'urugero rwawe ruteganyijwe, bashobora guhindura gahunda yawe.

Ntuzigere wongera imiti utabiherewe uburenganzira n'abaganga, kuko ibi bishobora gutera kwiyongera. Ikipe yawe y'ubuzima bw'imyororokere izafasha kumenya uburyo bwiza bwo gukora bushingiye ku ho uri mu cyiciro cy'ubuvuzi bwawe n'uko umubiri wawe wabyitwayemo.

Nshobora guhagarika ryari gufata Urofollitropin?

Uzahagarika gufata urofollitropin mugihe muganga wawe amenye ko imitsi yawe igeze ku bunini bukwiye n'ubusharire. Icyemezo gishingiye ku rwego rw'imisemburo yo mu maraso n'ibipimo bya ultrasound, ntabwo bishingiye ku mubare w'iminsi wagenwe.

Muri rusange, uzahabwa

Niba igihe cyo kuvura gikeneye guhagarikwa kubera igisubizo gike cyangwa ibyago byo kuremererwa, muganga wawe azahagarika imiti. Ntukihagarike gufata urofollitropin wenyine utagishishanyijeho na muganga, kuko ibyo bishobora guta igihe cyose cyo kuvurwa.

Nshobora gukora imyitozo ngororamubiri niba ndimo gufata Urofollitropin?

Imyitozo ngororamubiri yoroheje kugeza ku gipimo giciriritse muri rusange ni amahoro mugihe ufata urofollitropin, ariko uzakenera kwirinda imyitozo ikomeye cyangwa ibikorwa bishobora guteza uruguma ku ngingo z'abagore. Mu gihe imitsi yawe y'abagore yiyongera mugihe cyo kuvurwa, irushaho kwangirika.

Kugenda, yoga yoroheje, no koga byoroheje mubisanzwe birakora, ariko irinda kwiruka, gukoresha ibyuma biremereye, cyangwa igikorwa icyo aricyo cyose kirimo gusimbuka cyangwa guhindura imyitozo. Muganga wawe azatanga amabwiriza yihariye ashingiye ku buryo imitsi yawe y'abagore isubiza ku kuvurwa.

Nyuma mu gihe cyo kuvurwa kwawe, cyane cyane nyuma yo kurasa, ushobora gukenera kwirinda imyitozo rwose kugeza umenye niba utwite. Ibi bifasha kurengera imitsi yawe y'abagore yiyongereye n'icyo aricyo cyose gishoboka cyo gutwita kare.