Icyo Varenicline ari cyo: Ibyo ikoreshwa, urugero rwo gufata, ingaruka zayo n'ibindi

Varenicline ni umuti wandikirwa abantu ugamije gufasha abantu kureka itabi. Ikora yibanda ku byakira by'ubwonko bimwe na bimwe nicotine igiraho ingaruka, bituma itabi ritaryoha cyane mugihe rigabanya ibimenyetso byo kuva ku itabi no kurirarikira.

Uyu muti wafashije abantu babarirwa muri za miliyoni kwikura mu burozi bw'itabi. Kumva uko ikora n'icyo witegura bishobora kugufasha gufata ibyemezo bifitiye akamaro ku rugendo rwawe rwo kureka itabi.

Varenicline ni iki?

Varenicline ni umuti wo kureka itabi ukora ku byakira bya nicotine byo mu bwonko bwawe. Yagenewe by'umwihariko gufasha abantu bakuru kureka itabi mugihe igabanya ibyishimo ubona mu itabi ndetse n'ibimenyetso bitari byiza byo kuva ku itabi.

Uyu muti ubarirwa mu cyiciro cy'imiti yitwa nicotinic receptor partial agonists. Tekereza nk'umusimbura woroshye wuzura igice kimwe cy'ahantu hamwe mu bwonko bwawe nicotine isanzwe yuzura. Iki gikorwa cyombi gifasha guca uruziga rw'uburozi mugihe gikora impinduka kuva ku itabi biroroshye.

Varenicline iboneka gusa ku itegeko rya muganga kandi bisaba ubugenzuzi bw'ubuvuzi bwitondewe. Muganga wawe azemeza niba ari wo mwanzuro ukwiye hashingiwe ku mateka yawe yo kunywa itabi, ubuzima bwawe muri rusange, n'indi miti ushobora kuba ufata.

Varenicline ikoreshwa kubera iki?

Varenicline ikoreshwa cyane cyane mu gufasha abantu bakuru kureka itabi. Yemerejwe by'umwihariko gukoreshwa mu kureka itabi kandi ikora neza cyane iyo ihujwe n'inama n'inkunga.

Uyu muti wagenewe abantu biyemeje kureka itabi kandi bagerageje izindi nzira ntizigire icyo zigeraho. Bifasha cyane cyane abantu bahura no kurarikira cyane cyangwa ibimenyetso bikomeye byo kuva ku itabi mugihe bagerageza kureka.

Abaganga bamwe bashobora no kwandikira varenicline ku bindi bicuruzwa bya itabi, nubwo kunywa itabi ryo mu dukaramu ari ryo rikoreshwa cyane. Uyu muti ntusabwa ku banywi b'itabi rimwe na rimwe cyangwa abanywa itabi mu buryo bwo kwishimisha, ahubwo ukoreshwa ku bantu bafite ikibazo cyo gufatwa n'urugero rwo hejuru rwa nicotine.

Varenicline ikora ite?

Varenicline ikora igice cyo gukora imitsi ya nicotine mu bwonko bwawe icyarimwe ikabuza nicotine kwifatanya neza n'iyo mitsi. Ibi bituma habaho ingaruka zidasanzwe zifasha kureka kunywa itabi.

Iyo ufata varenicline, itanga urugero rwo gushishikariza kugabanya ibimenyetso byo gukurwaho nk'uburakari, guhangayika, no kurarikira cyane. Muri icyo gihe, ibuza ibyishimo byinshi n'umunezero usanzwe ubona iyo unywa itabi, bigatuma itabi ritagira akamaro.

Uyu muti ufatwa nk'ukomeye ku rugero rwo hagati mu bijyanye n'ubushobozi. Ubushakashatsi bwa kliniki bwerekana ko bushobora gukuba kabiri cyangwa gatatu amahirwe yawe yo kureka kunywa itabi neza ugereranije no gukoresha ubushake gusa. Ariko, si umuti w'ubumaji kandi ukora neza iyo wiyemeje rwose kureka kunywa itabi.

Ingaruka zo kubuza bisobanura ko nubwo unywa itabi mugihe ufata varenicline, ntuzabona umunezero usanzwe cyangwa umunezero. Ibi bifasha guca uruziga rw'ibihembo byo mu mutwe bituma abantu baguma mu itabi.

Nkwiriye gufata varenicline nte?

Varenicline ikwiriye gufatwa nkuko byategetswe na muganga wawe, akenshi gutangira icyumweru kimwe mbere y'itariki yawe yo kureka kunywa itabi. Uyu muti uza mu buryo bw'ibinini kandi akenshi ufatanwa kabiri ku munsi hamwe n'ibiryo n'ikirahure cyuzuye cy'amazi.

Muganga wawe ashobora gutangira kugutera urugero ruto mu minsi mike ya mbere, hanyuma buhoro buhoro akarwongera. Ibi bifasha umubiri wawe kumenyera umuti kandi bigabanya ibyago byo kugira ingaruka ziterwa n'umuti. Kuwufata hamwe n'ibiryo bifasha kwirinda isesemi, ikaba ari imwe mu ngaruka zisanzwe ziterwa n'umuti.

Ni ngombwa kurya ifunguro risanzwe cyangwa ifunguro rirambye mbere yo gufata urugero rwose. Irinde gufata varenicline ku gifu cyambaye ubusa, kuko ibyo byongera cyane amahirwe yo kumva uruka cyangwa kugira ikibazo cyo mu nda.

Gerageza gufata imiti yawe ku gihe kimwe buri munsi kugira ngo ugumane urwego ruzigama mu mubiri wawe. Abantu benshi babona ko bifasha gufata urugero rumwe hamwe n'ifunguro rya mu gitondo n'urundi hamwe n'ifunguro rya nimugoroba kugira ngo bashyireho gahunda.

Nzagenda Mfata Varenicline Igihe Kingana Gite?

Abantu benshi bafata varenicline mu byumweru 12 (hafi amezi 3) nk'igice cy'umugambi wabo wo kureka itabi. Muganga wawe ashobora kugusaba gukoresha igihe kirekire niba warashoboye kureka ariko ukeneye ubufasha bwiyongera kugira ngo ugumane intambwe yawe.

Igihe cyo kuvura gisanzwe gitangira icyumweru kimwe mbere y'itariki yo kureka kandi kigakomeza mu byumweru 11 nyuma yo kureka itabi. Abantu bamwe bashobora gukenera icyiciro cy'ibyumweru 12 niba barashoboye kureka ariko bafite ibyago byinshi byo gusubira inyuma.

Muganga wawe azagenzura intambwe yawe kandi ashobora guhindura igihe bitewe n'uko urimo gusubiza neza ku kuvurwa. Ibintu nk'amateka yawe yo kunywa itabi, imigeragezo yo kureka yabanje, n'urwego rwawe rw'umunaniro ubu byose bigira uruhare mu gihe ushobora gukenera umuti.

Ni ngombwa kutareka gufata varenicline ako kanya utabanje kuvugana na muganga wawe, kabone niyo wumva ko utagikeneye. Guhagarika buhoro buhoro bifasha kwirinda ingaruka zishobora guterwa no gukurwaho umuti ubwawo.

Ni Iyihe Ngaruka Ziterwa na Varenicline?

Varenicline irashobora gutera ingaruka, nubwo atari buri wese uzibona. Ingaruka zisanzwe ni zoroshye kandi akenshi ziragenda zikemuka uko umubiri wawe wimenyereza umuti.

Dore ingaruka zivugwa kenshi zikora ku bantu benshi bafata varenicline:

• Uburwayi bwo kuruka (bugera ku bantu 1 kuri 3)
• Inzozi zidasanzwe cyangwa zigaragara cyane
• Umutwe
• Kugorana gusinzira cyangwa kutagira ibitotsi
• Ukwituma bigoranye
• Gasa cyangwa kubyimba
• Impinduka mu buryohe
• Umunwa wumye

Ibi bimenyetso rusange bikunze gucungwa kandi akenshi bigabanuka nyuma y'ibyumweru bike bya mbere by'ubuvuzi.

Abantu bamwe bahura n'ingaruka ziteye inkeke zisaba ubufasha bw'ubuvuzi bwihuse. Nubwo ibi bidakunze kubaho, ni ngombwa kubimenya:

• Impinduka z'amarangamutima, harimo umubabaro cyangwa guhangayika
• Ibitekerezo byo kwiyahura cyangwa imyitwarire yo kwiyahura
• Imyitwarire y'urugomo cyangwa iy'ubugizi bwa nabi
• Urugero rukabije rw'uburwayi bwo kwivumbura ku bintu runaka hamwe n'imivumo, kubyimba, cyangwa kugorana guhumeka
• Ibibazo by'umutima cyangwa kuribwa mu gituza
• Udukorwa (bidakunze kubaho cyane)
• Kugenda mu gihe cy'ibitotsi cyangwa izindi myitwarire idasanzwe yo gusinzira

Niba uhuye n'imwe muri izi ngaruka zikomeye, vugana n'umuganga wawe ako kanya cyangwa ushake ubufasha bw'ubuvuzi bwihutirwa. Umutekano wawe ni wo uza imbere, kandi izi ngaruka zikeneye isuzuma ry'ubuvuzi bwihuse.

Ninde utagomba gufata Varenicline?

Varenicline ntabwo ikwiriye kuri buri wese, kandi abantu bamwe bagomba kwirinda uyu muti kubera ibyago byiyongereye. Umuganga wawe azasuzuma neza amateka yawe y'ubuvuzi mbere yo kuwugusaba.

Ntabwo ugomba gufata varenicline niba ufite allergie izwi ku muti cyangwa ibikubiye muri wo. Abantu bafite indwara zimwe na zimwe zo mu mutwe bashobora no gukenera kuwureka cyangwa bagasaba gukurikiranwa by'umwihariko.

Aha hari amatsinda y'ingenzi y'abantu bagomba kwitonda cyangwa kwirinda varenicline rwose:

• Abantu bafite amateka yo kwiheba bikabije cyangwa ibitekerezo byo kwiyahura
• Abafite indwara ya bipolar cyangwa izindi ndwara zikomeye zo mu mutwe
• Abantu bafite indwara zikomeye z'impyiko
• Abantu bagiye bagira ibibazo byo gufatwa n'indwara ya epilepsi
• Abafite amateka y'ibibazo by'umutima cyangwa indwara z'imitsi y'amaraso
• Abagore batwite cyangwa bonka
• Abantu bari munsi y'imyaka 18

Muganga wawe azagereranya inyungu n'ibibazo byihariye byawe. Rimwe na rimwe inyungu zo kureka itabi ziruta ibibazo bishobora guterwa no gufata varenicline, nubwo ufite indwara zimwe na zimwe.

Amazina y'ubwoko bwa Varenicline

Varenicline izwi cyane ku izina ry'ubwoko rya Chantix muri Leta Zunze Ubumwe z'Amerika. Iri ni izina ry'ubwoko ry'umwimerere ryakoreshejwe bwa mbere mu kwamamaza umuti kandi rigikoreshwa cyane.

Mu bindi bihugu, varenicline ishobora kugurishwa ku mazina y'ubwoko atandukanye, harimo Champix muri Kanada, mu Bwongereza, no ku masoko mpuzamahanga menshi. Umuti nyirizina uracyari umwe nubwo izina ry'ubwoko ryahinduka.

Ubwoko bwa varenicline bwa rusange buraboneka kandi mu turere tumwe na tumwe, bukaba burimo umuti umwe nyirizina ariko bushobora kugura make ugereranije n'ubwoko bw'amazina. Umufarimasi wawe ashobora kugufasha gusobanukirwa ubwoko urimo gufata.

Uburyo bwo gusimbuza Varenicline

Niba varenicline itagukwiriye, hari imiti itandukanye yemejwe na FDA ishobora gufasha mu kureka itabi. Buri umwe ukora mu buryo butandukanye kandi ushobora gukwira neza ibyo ukeneye n'amateka yawe y'ubuvuzi.

Ubuvuzi bwo gusimbuza nicotine akenshi ni uburyo bwa mbere abantu bagerageza. Ibi birimo ibishishwa, chingamu, amavuta, imiti yo mu mazuru, n'ibikoresho byo guhumeka bitanga nicotine ifatika idafite imiti yangiza iboneka mu itabi.

Bupropion (Zyban) ni undi muti wandikirwa ushobora gufasha mu kureka itabi. Ni umuti uvura umubabaro unagabanya inyota ya nicotine n'ibimenyetso byo gukurwaho, nubwo ukora ukoresheje uburyo butandukanye na varenicline.

Uburyo butifashisha imiti nko kugisha inama, amatsinda ashyigikira, imyitwarire, na porogaramu zigendanwa na zo zirashobora kugira akamaro, haba wenyine cyangwa uhujwe n'imiti. Abantu benshi babona intsinzi hamwe n'uruvange rw'uburyo aho kwishingikiriza ku buryo bumwe gusa.

Ese Varenicline iruta ubuvuzi bwo gusimbuza nicotine?

Varenicline yagaragajwe ko ifite akamaro kurusha ubuvuzi bwo gusimbuza nicotine mu bushakashatsi bwa kliniki. Ubushakashatsi bwerekana ko varenicline ishobora gufasha hafi 20-25% by'abantu kureka itabi igihe kirekire, ugereranije na 10-15% hamwe na nicotine patches cyangwa gum.

Ariko,

Umuvuzi w'umutima wawe n'umuganga wawe w'ibanze bagomba gukorana kugira ngo basuzume niba varenicline ifite umutekano kuri wowe. Bazatekereza ku bwoko bwihariye bw'indwara y'umutima ufite, uko ifashwe neza, n'ubuzima bwawe bwose bw'imitsi y'umutima.

Ku bantu benshi barwaye indwara y'umutima, inyungu zo kureka itabi ziruta cyane ibyago bishobora guterwa no gufata varenicline. Kunywa itabi ubwaryo ni kimwe mu bintu bibi cyane ushobora gukora ku mutima wawe, bityo kureka kunywa itabi neza akenshi bitanga inyungu zikomeye ku mutima.

Nkwiriye gukora iki niba mfashwe varenicline nyinshi ku buryo butunganye?

Niba ufashwe varenicline nyinshi ku buryo butunganye kuruta uko byategetswe, vugana n'umuganga wawe cyangwa ikigo gishinzwe kurwanya ubumara ako kanya. Gufata nyinshi bishobora kongera ibyago byo kugira ingaruka zikomeye nk'ibibazo byo gufatwa cyangwa ibibazo by'umutima.

Ntugategereze ngo urebe niba wumva umeze neza. N'iyo utabonye ibimenyetso ako kanya, gukoresha doze nyinshi biracyashobora kuba byateza akaga. Hamagara Ikigo gishinzwe kurwanya ubumara kuri 1-800-222-1222 cyangwa ushake ubufasha bw'ubuvuzi bwihutirwa ako kanya.

Gerageza kugira icupa ry'imiti hamwe nawe igihe uhamagaye cyangwa ujya kwa muganga. Ibi bifasha abaganga kumenya neza urugero wafashe n'igihe, ibyo bikaba ari ingenzi kugira ngo uvurwe neza.

Nkwiriye gukora iki niba nciwe doze ya varenicline?

Niba waciwe doze ya varenicline, yifate ako kanya wibuka, keretse igihe cyo gufata doze yawe ikurikira kigeze. Muri icyo gihe, reka doze waciwe ukomeze gahunda yawe isanzwe.

Ntuzigere ufata doze ebyiri icyarimwe kugira ngo usimbuze doze waciwe. Ibi bishobora kongera ibyago byo kugira ingaruka zikomeye utagize inyungu zinyongera zo kureka itabi.

Niba ukunda kwibagirwa doze, gerageza gushyiraho ibyibutso kuri terefone cyangwa ukoreshe umuteguro w'imiti. Gufata imiti buri gihe ni ingenzi kugira ngo varenicline ikore neza, bityo gushyiraho gahunda bifasha kugera ku ntsinzi.

Nshobora kureka gufata varenicline ryari?

Ugomba kurangiza umuti wa varenicline uko wategetswe na muganga wawe, n'iyo wumva ko utawukeneye. Abantu benshi bawufata mu gihe cy'ibyumweru 12, kandi kuwuhagarika mbere y'igihe bishobora kongera ibyago byo kongera gutangira kunywa itabi.

Niba urimo guhura n'ingaruka zidakwirwa, ganira na muganga wawe mbere yo guhagarika. Ashobora kugabanya urugero rw'umuti ukoresha cyangwa akagusaba uburyo bwo guhangana n'izo ngaruka aho guhagarika umuti rwose.

Abantu bamwe bungukirwa no kugabanya urugero rw'umuti buhoro buhoro aho guhagarika ako kanya. Muganga wawe azakugira inama ku buryo bwiza bwo guhagarika varenicline bitewe n'intambwe umaze gutera n'uko ubuzima bwawe bwite bumeze.

Nshobora kunywa inzoga nkanwa varenicline?

Ugomba kwitonda cyane ku kunywa inzoga nkanwa varenicline. Abantu bamwe bahura no kwiyongera k'ubushobozi bwo kumva inzoga, bivuze ko bumva basinze vuba cyangwa cyane kuruta uko bisanzwe.

Inzoga kandi ishobora gutuma zimwe mu ngaruka za varenicline zirushaho kuba mbi, cyane cyane isesemi no kuribwa umutwe. Byongeye kandi, kunywa inzoga bishobora gutuma bigorana gukurikiza gahunda yawe yo kureka kunywa itabi.

Niba uhisemo kunywa, bikore mu rugero ruto kandi witondere uko wumva. Abantu benshi basanga bifasha kwirinda inzoga rwose mu rugendo rwabo rwo kureka kunywa itabi kugira ngo bihe amahirwe menshi yo gutsinda.