Vilazodone ni iki: Ibikoreshwa, Urutonde rw'imiti, Ingaruka zayo n'ibindi

Vilazodone ni umuti wandikirwa n'abaganga uvura indwara yo kwiheba mu bantu bakuru. Uherereye mu cyiciro gishya cy'imiti ivura kwiheba yitwa serotonin partial agonist reuptake inhibitors (SPARIs), ikora mu buryo butandukanye n'imiti ya kera ivura kwiheba. Ushobora kuyimenya neza ku izina ry'ubucuruzi rya Viibryd, kandi igamije gufasha kugarura uburinganire bwa serotonin mu bwonko bwawe mugihe bishobora gutera ingaruka nke zo mu mibonano mpuzabitsina kurusha imiti imwe ivura kwiheba.

Vilazodone ni iki?

Vilazodone ni ubwoko bwihariye bw'umuti uvura kwiheba uhuza uburyo bubiri butandukanye bwo gufasha kuvura kwiheba. Bitandukanye n'imiti ya kera ivura kwiheba ikora mu buryo bumwe gusa, vilazodone yombi irabuza serotonin reuptake kandi igahindura igice cy'imikorere ya serotonin receptors mu bwonko bwawe. Iyi mikorere ibiri ifasha kongera uboneka bwa serotonin, intumwa ya chimique igira uruhare runini mu kugenga imitekerereze.

Uyu muti watejwe imbere by'umwihariko kugirango ukemure imbogamizi zimwe na zimwe z'imiti ya kera ivura kwiheba, cyane cyane zijyanye n'ingaruka zo mu mibonano mpuzabitsina. Ifatwa nk'umuti uvura kwiheba ufite imbaraga ziringaniye ushobora kugira akamaro ku bantu benshi bafite kwiheba mugihe bishobora kuba byoroshye ku mikorere y'imibonano mpuzabitsina ugereranije na SSRIs nka sertraline cyangwa paroxetine.

Vilazodone ikoreshwa mu iki?

Vilazodone ikoreshwa cyane cyane mu kuvura indwara yo kwiheba mu bantu bakuru bafite imyaka 18 n'abarenze. Muganga wawe ashobora kukugiraho inama niba urimo guhura n'ibyiyumvo bihoraho by'agahinda, kumva nta cyizere, cyangwa gutakaza inyungu mu bikorwa wahoze ukunda. Bifasha cyane cyane abantu bagerageje indi miti ivura kwiheba ariko bagahura n'ingaruka ziteye impungenge zo mu mibonano mpuzabitsina.

N'ubwo agahinda gakabije ari cyo kintu cyemewe gukoreshwa, abaganga bamwe bashobora kwandika vilazodone hanze y'icyo cyemezo ku bibazo byo guhangayika, nubwo atari cyo kimenyetso cyayo cy'ibanze. Uyu muti ukora neza ku bantu bafite agahinda gakabije kugeza ku rwo rwo hejuru bakeneye kuvurwa buri munsi kugira ngo bacunge neza ibimenyetso byabo.

Vilazodone ikora ite?

Vilazodone ikora ikoresheje uburyo bubiri butuma itandukana n'izindi nshya zivura agahinda gakabije. Icya mbere, ibuza gusubizwa kwa serotonin, bivuze ko ibuza ubwonko bwawe gukuraho vuba uyu muti w'imitekerereze mu mwanya uri hagati y'uturemangingo tw'imitsi. Icya kabiri, ikora igice cy'imbaraga ku bice bimwe na bimwe bya serotonin, ibi bifasha kunoza uburyo ubwonko bwawe bwakira serotonin.

Bitekereze nk'uko byongera umubare wa serotonin uboneka kandi bigafasha ubwonko bwawe kuyikoresha neza. Ubu buryo buhuriweho busanzwe bufata ibyumweru 4 kugeza kuri 6 kugira ngo bwerekane ingaruka zayo zose, nubwo abantu bamwe bashobora kubona impinduka mu gusinzira cyangwa mu rwego rw'icyifuzo mu cyumweru cya mbere cyangwa icya kabiri. Uyu muti ufashwe nk'ufite imbaraga ziringaniye, bivuze ko ukora neza ku bantu benshi bafite agahinda gakabije ariko ntushobora kuba wo guhitamo neza ku bibazo bikomeye cyane.

Nkwiriye gufata gute Vilazodone?

Vilazodone igomba gufatwa hamwe n'ibiryo kugira ngo byemeze ko ifashwe neza kandi bigabanye ibibazo byo mu nda. Ufate ku gihe kimwe buri munsi, cyane cyane hamwe n'ifunguro rikomeye ririmo byibura kalori 300-400. Ibi si igitekerezo gusa - kuyifata utarya birashobora kugabanya umubare w'umuti umubiri wawe ufata kugeza kuri 50%.

Abantu benshi batangira na 10mg rimwe ku munsi mu cyumweru cya mbere, hanyuma bakazamuka bakagera kuri 20mg ku munsi mu cyumweru cya kabiri, hanyuma bakagera ku rugero rwa 40mg ku munsi. Muganga wawe azakuyobora muri uku kuzamuka gake gake kugira ngo afashe umubiri wawe guhuza no kugabanya ingaruka ziterwa. Mimina ibinini byose hamwe n'amazi, kandi ntukabice, ntukayisye, cyangwa ngo uyitandukanye.

Niba ugira ikibazo cyo kwibuka kuyifata hamwe n'ibiryo, gerageza gushyiraho alarme ya buri munsi yo gufata ifunguro. Abantu benshi babona ko bifasha gufata vilazodone hamwe na saftani cyangwa nimugoroba, ifunguro iryo ariryo ryose rikunze kuboneka muri gahunda zabo.

Nzagomba Kumara Igihe Kingana Gite Nda Vilazodone?

Abantu benshi bakeneye gufata vilazodone byibuze amezi 6 kugeza kuri 12 nyuma y'uko ibimenyetso byabo byo kwiheba bigabanuka. Iki gihe cyo gukomeza gifasha kwirinda ko kwiheba bigaruka, ibyo bikunze kubaho iyo imiti igabanya kwiheba ihagaritswe kare cyane. Muganga wawe azakorana nawe kugira ngo amenye igihe gikwiye gishingiye ku miterere yawe bwite n'amateka yawe.

Ku bantu bahura n'icyiciro cyabo cya mbere cyo kwiheba, imiti ikunze kumara amezi 6 kugeza kuri 12 nyuma y'uko ibimenyetso bigabanuka. Niba waragize ibyiciro byinshi byo kwiheba, muganga wawe ashobora kugusaba imiti y'igihe kirekire kugira ngo ifashe kwirinda ibyiciro by'ahazaza. Abantu bamwe bungukirwa no gufata vilazodone imyaka myinshi, cyane cyane niba baragize kwiheba kugaruka.

Ntuzigere uhagarika gufata vilazodone ako kanya, n'iyo wumva umeze neza. Muganga wawe azagufasha kugabanya buhoro buhoro urugero mu byumweru byinshi kugira ngo wirinde ibimenyetso byo gukurwaho nk'izunguruka, isesemi, cyangwa impinduka z'imitekerereze.

Ni Ibihe Bikorwa Bigaragara Bya Vilazodone?

Kimwe n'imiti yose, vilazodone ishobora gutera ibikorwa bigaragara, nubwo abantu benshi bayihanganira neza. Ibikorwa bigaragara bikunze kubaho muri rusange biroroshye kandi akenshi birakosoka uko umubiri wawe ukimenyereza imiti mu byumweru bya mbere.

Dore ibikorwa bigaragara bikunze gutangazwa bikora ku bantu barenga 5% bafata vilazodone:

• Isesemi n'igifu kitameze neza (cyane cyane mu byumweru bya mbere)
• Impiswi cyangwa imyanda yoroshye
• Izunguruka cyangwa umutwe woroheje
• Ikibazo cyo gusinzira cyangwa inzozi zidasanzwe
• Umunaniro cyangwa kumva unaniwe ku manywa
• Umunwa wumye
• Kugabanya ubushake bwo kurya

Inshuro nyinshi z'ibi bimenyetso bigaragara byo ku ruhande ni iby'igihe gito kandi bikunda gushira uko umubiri wawe umenyera umuti. Gufata vilazodone hamwe n'ibiryo bishobora kugabanya cyane isesemi n'ibimenyetso bigaragara byo ku ruhande bifitanye isano n'igifu.

Abantu bamwe bahura n'ibimenyetso bigaragara byo ku ruhande bitamenyerewe ariko biteye impungenge bikaba bisaba ubufasha bwa muganga. Ibi birimo ibimenyetso bikomeye byo kwibasirwa n'umubiri, kuva amaraso cyangwa gukomereka bidasanzwe, impinduka zikomeye z'imitekerereze, cyangwa ibitekerezo byo kwangiza. Nubwo bidasanzwe, ibi bimenyetso bikomeye bigomba gusuzumwa n'abaganga ako kanya.

Ibimenyetso bigaragara byo ku ruhande bifitanye isano n'imibonano mpuzabitsina, nubwo bitamenyerewe kuri vilazodone kurusha izindi ntungamubiri, biracyashobora kubaho ku bantu bamwe. Ibi bishobora kuba birimo kugabanuka k'urukundo, kugorana kugera ku byishimo, cyangwa kutagira ubushobozi bwo gushyira mu bikorwa ku bagabo. Niba uhuye n'ibi bimenyetso, ganira na muganga wawe ku bisubizo bishoboka.

Ninde utagomba gufata Vilazodone?

Vilazodone ntirinzwe kuri buri wese, kandi hariho ibintu byinshi by'ingenzi bigomba kwirindwa cyangwa gukoreshwa witonze cyane. Ntukigere ufata vilazodone niba uri gufata cyangwa umaze igihe gito uhagaritse gufata MAOIs (monoamine oxidase inhibitors), kuko iyi mvange ishobora gutera indwara yitwa serotonin syndrome.

Abantu bafite indwara zimwe na zimwe bagomba kubanza gusuzumwa mbere yo gutangira gufata vilazodone. Niba ufite indwara ikomeye y'umwijima cyangwa impyiko, muganga wawe ashobora gukenera guhindura urugero rwawe cyangwa agahitamo undi muti. Abafite amateka y'indwara z'amaraso, ibibazo byo gufatwa n'indwara, cyangwa indwara ya bipolar nabo basaba gukurikiranwa neza.

Urubyiruko ruri munsi y'imyaka 25 rukeneye gukurikiranwa cyane, kuko ntungamubiri rimwe na rimwe zishobora kongera ibitekerezo byo kwiyahura muri iki cyiciro cy'imyaka mu mezi make ya mbere yo kuvurwa. Abagore batwite cyangwa bonka bagomba kuganira ku byago n'inyungu n'umuganga wabo, kuko vilazodone ishobora kwimurirwa ku mwana.

Niba ufata imiti ituma amaraso atavura vuba, imiti ya NSAIDs, cyangwa indi miti igira ingaruka ku rwego rwa serotonin, muganga wawe azagomba gusuzuma neza uko iyo miti ishobora kugirana imikoranire mbere yo kugushyiriraho vilazodone.

Izina ry'ubwoko bwa Vilazodone

Vilazodone izwi cyane ku izina ry'ubwoko bwayo rya Viibryd, ikorwa na Allergan (ubu ni igice cya AbbVie). Iri ni ryo zina ry'ubwoko ry'umwimerere imiti yabanje kwemezwa na FDA mu 2011. Ushobora kubona iri zina ryanditse nka "Viibryd" ku icupa ry'umuti wawe cyangwa ku mpapuro z'ubwishingizi.

Ubwoko bwa vilazodone bwa rusange bwabonetse mu myaka yashize, bushobora kuba buhendutse cyane kurusha ubwoko bw'umuti. Uwo muti wa rusange urimo ibintu bikora kimwe kandi ukora kimwe na Viibryd, bityo ntugire impungenge niba farumasi ikwimuriye ku bwoko bwa rusange.

Izindi miti isimbura Vilazodone

Niba vilazodone itagukundiye cyangwa ikagutera ingaruka zikomeye, hari izindi miti zihari zishobora kuyisimbura. Imiti ya SSRIs nka sertraline, escitalopram, cyangwa fluoxetine akenshi ifatwa nk'imiti ikoreshwa mbere na mbere mu kuvura umubabaro, nubwo ishobora kugira ingaruka nyinshi ku mibonano mpuzabitsina kurusha vilazodone.

Izindi miti mishya ivura umubabaro harimo bupropion, ikora mu buryo butandukanye kandi ntigire ingaruka ku mibonano mpuzabitsina, cyangwa vortioxetine, ifite uburyo bubiri bwo gukora kimwe na vilazodone. Imiti ya SNRIs nka duloxetine cyangwa venlafaxine itanga ubundi buryo, cyane cyane niba ufite kandi umunabi cyangwa ububabare buhoraho.

Muganga wawe azasuzuma ibimenyetso byawe byihariye, amateka yawe y'ubuzima, indi miti ufata, n'uburyo wabanje kuvurwa mbere yo kugusaba izindi miti. Rimwe na rimwe gushaka umuti ukwiriye uvura umubabaro bisaba kugerageza uburyo butandukanye, kandi uru rugendo rusaba kwihangana no kuvugana cyane n'umuganga wawe.

Ese Vilazodone iruta Sertraline?

Vilazodone na sertraline zombi zifite akamaro mu kuvura umubabaro, ariko zikora mu buryo butandukanye kandi zikagira ingaruka zitandukanye. Nta na rimwe rifite agaciro kanini kurusha irindi - guhitamo neza biterwa n'ibyo ukeneye ku giti cyawe n'uko umubiri wawe witwara kuri buri muti.

Vilazodone ishobora kugira akamaro mu bijyanye n'ingaruka zifitanye isano n'imibonano mpuzabitsina, kuko ubushakashatsi bwerekana ko bidashoboka ko itera ibibazo bifitanye isano n'imikorere y'imibonano mpuzabitsina ugereranyije na sertraline. Ariko, sertraline imaze igihe kirekire ikoreshwa kandi ifite ubushakashatsi bwinshi bushingiye ku ikoreshwa ryayo mu kuvura indwara zitandukanye zirenga umubabaro, harimo indwara zo guhangayika na OCD.

Sertraline kandi iboneka nk'umuti rusange kandi akenshi ihendutse kurusha vilazodone. Abantu bamwe basanga sertraline byoroshye kuyifata kuko ntisaba kurya kugira ngo ikore neza, mu gihe vilazodone igomba gufatwa hamwe n'ifunguro rikomeye. Muganga wawe ashobora kugufasha gupima ibi bintu kugira ngo umenye umuti ushobora kuba mwiza kuruta undi ku bijyanye n'ikibazo cyawe.

Ibikunze Kubazwa Kuri Vilazodone

Ese Vilazodone irakwiriye ku barwayi b'umutima?

Vilazodone muri rusange ifatwa nk'umuti ukwiriye ku bantu bafite indwara z'umutima, ariko bisaba gukurikiranwa neza. Bitandukanye na bimwe mu miti ya kera ivura umubabaro, vilazodone akenshi ntigira impinduka zikomeye mu mutima cyangwa umuvuduko w'amaraso. Ariko, ishobora gukorana n'imiti ituma amaraso atavura, iyo miti ikaba ikoreshwa n'abarwayi benshi b'umutima.

Niba ufite indwara y'umutima, muganga wawe ashobora kugutangira urugero ruto kandi akagukurikiranira hafi. Bazareba kandi imiti yose ufata ku mutima kugira ngo barebe niba hari ibishobora kuvuka. Abantu benshi bafite indwara z'umutima zidakomeye bashobora gufata vilazodone neza, ariko iki cyemezo kigomba gufatwa buri gihe muganga w'umutima na muganga w'indwara zo mu mutwe bakorana.

Nigira nte niba mfata vilazodone nyinshi mu buryo butunganye?

Niba wanyoye umuti wa vilazodone urenze urugero wagombaga kunywa, vugana n'umuganga wawe cyangwa ikigo gishinzwe ubumara ako kanya. Kunywa umuti mwinshi bishobora gutera ibimenyetso nk'isuka ikabije, kuruka, isereri, umutima guteragura cyane, cyangwa urujijo. Mu bihe bikomeye, bishobora gutera indwara ya serotonin, isaba ubuvuzi bwihutirwa.

Ntugategereze ngo urebe niba ibimenyetso bigaragara - ni byiza kubaza inama z'abaganga ako kanya. Niba urimo guhura n'ibimenyetso bikomeye nk'ingorane zo guhumeka, kuribwa mu gituza, cyangwa kutagira ubwenge, hamagara serivisi z'ubutabazi ako kanya. Bika icupa ry'umuti hamwe nawe kugira ngo abaganga babone neza icyo wanyoye n'ingano yacyo.

Nkwiriye gukora iki niba nibagiwe kunywa urugero rwa vilazodone?

Niba wibagiwe kunywa urugero rwa vilazodone, unywe ako kanya wibukije, ariko niba ushobora kurunywa hamwe n'ibiryo. Niba igihe cyo kunywa urugero rukurikira kigeze (mu masaha 4-6), reka urugero wibagiwe hanyuma ukomeze gahunda yawe isanzwe. Ntukigere unywa urugero rurenze rumwe kugira ngo usimbure urugero wibagiwe.

Kutanywa urugero rimwe na rimwe ntizitera ibibazo bikomeye, ariko gerageza gukomeza kunywa imiti buri munsi kugira ngo ubone ibisubizo byiza. Niba ukunda kwibagirwa kunywa imiti, tekereza gushyiraho alarme ya buri munsi cyangwa gukoresha umuteguro w'imiti. Abantu bamwe basanga bifasha kunywa vilazodone yabo hamwe n'ifunguro rimwe buri munsi kugira ngo bubake gahunda.

Nshobora kureka kunywa vilazodone ryari?

Wagombye kureka kunywa vilazodone gusa ukurikije ubuyobozi bw'umuganga wawe, kabone n'iyo wumva umeze neza cyane. Abantu benshi bakeneye gukomeza kuvurwa byibuze amezi 6 kugeza kuri 12 nyuma y'uko ibimenyetso byabo bigabanutse kugira ngo birinde ko agahinda gasubira. Kureka kare cyane byongera cyane ibyago byo gusubira mu burwayi.

Iyo wowe na muganga wawe mwemeje ko igihe kigeze cyo guhagarika, uzagabanya buhoro buhoro urugero rw'umuti mu byumweru byinshi aho guhagarika ako kanya. Ubu buryo bwo kugabanya bufasha kwirinda ibimenyetso byo kuva ku muti nk'izunguzungu, isesemi, umujinya, cyangwa impinduka z'amarangamutima. Igihe nyacyo cyo kugabanya giterwa n'igihe umaze ufata umuti n'uburyo umubiri wawe ubyakira.

Nshobora kunywa inzoga nkanwa Vilazodone?

Ni byiza kwirinda inzoga cyangwa kuzigabanya cyane mugihe ufata vilazodone. Inzoga irashobora gukomeza ibimenyetso byo kwiheba kandi irashobora kongera ibyago byo kugira ingaruka zirimo izunguzungu, gusinzira cyane, cyangwa kugorwa no kwibuka. Ubu buvuzi bushobora no gutuma udashobora gutekereza neza no guhuza ibikorwa byawe kurusha uko byaba bimeze kuri kimwe muri ibyo bintu.

Niba uhisemo kunywa rimwe na rimwe, wigabanyirize ku kinyobwa kimwe urebe uko wumva. Abantu bamwe basanga bafite ubwumvikane bwinshi ku nzoga mugihe bafata vilazodone. Ntukoreshe inzoga kugirango uhangane n'ibimenyetso byo kwiheba, kuko ibi bishobora kubangamira imiti yawe kandi bishobora gutera ingaruka zikomeye hamwe n'imiti yawe.