Ni iki Xenon-Xe-129 Hyperpolarized: Ibikoresho, Urutonde rw'imiti, Ingaruka ziterwa n'ibindi

Xenon-Xe-129 hyperpolarized ni umuti wihariye wifashishwa mu gushushanya ushobora guhumeka mu gihe cyo gukoresha ibizamini bimwe na bimwe by'ibihaha. Ibi si umuti usanzwe wafata mu rugo - ni igikoresho cy'ubuvuzi cy'ikoranabuhanga rikoreshwa mu bitaro kugira ngo hakorwe amashusho arambuye cyane y'ibihaha byawe n'uko bikora.

Tekereza nk'uburyo buhanitse cyane abaganga bareba imbere mu bihaha byawe mugihe bikora. Igice cya "hyperpolarized" gisobanura ko abahanga batanze gazi ya xenon imitungo yihariye ya magneti ituma igaragara neza cyane kuri MRI scans, itanga ikipe yawe y'ubuvuzi isesengura neza imikorere y'ibihaha byawe.

Ni iki Xenon-Xe-129 Hyperpolarized?

Xenon-Xe-129 hyperpolarized ni gazi nziza yateguwe byihariye kugira ngo yongere imikorere ya MRI y'ibihaha byawe. Xenon isanzwe iboneka mu kirere kidukikije, ariko iyi verisiyo y'ubuvuzi yateganijwe kugira ngo igaragarire cyane kuri scans.

Ubu buryo bukubiyemo gukoresha laser n'uburyo bwihariye bwo guhuza atome ya xenon mu buryo butuma zikora nk'utuntu duto twa magneti. Iyo uhumeka iyi gazi yateguwe, igenda mu bihaha byawe ikora amashusho arambuye agaragaza neza uko umwuka ugenda mu nzira yawe yo guhumeka.

Ubu buryo bwo gushushanya buracyari bushya kandi bugereranya imwe mu nzira zateye imbere cyane abaganga bashobora kwiga imikorere y'ibihaha nta buryo na bumwe bwo kubagwa. Bitandukanye rwose na scans ya CT isanzwe kuko yerekana ibihaha byawe bikora mu gihe nyacyo.

Xenon-Xe-129 Hyperpolarized ikoreshwa kubera iki?

Abaganga bakoresha uyu muti wihariye wo gushushanya kugira ngo basuzume kandi bakurikirane indwara zitandukanye z'ibihaha bigoye kubona hamwe na scans zisanzwe. Bifitiye akamaro cyane kumva neza uko ibice bitandukanye by'ibihaha byawe bikora.

Indwara z'ibanze iyi shusho ifashisha cyane zirimo indwara y'umwuka mubi (COPD), asima, na emboli ya pulumonari (amaraso yiziba mu muhaha). Muganga wawe ashobora no kubikugiraho inama niba ufite guhumeka bigoye bitumvikana cyangwa niba izindi igeragezwa ry'umuhaha ritatanze ibisubizo bisobanutse.

Usibye indwara zisanzwe z'umuhaha, iyi shusho ishobora kumenya indwara zitavugwa cyane nka hypertension ya pulumonari, aho imitsi y'amaraso mu muhaha wawe yiyongereyeho umuvuduko. Ishobora kandi gufasha gusuzuma abantu bakiriye impyiko z'umuhaha kugirango barebe uko impyiko nshya zikora neza.

Rimwe na rimwe abaganga barayikoresha kugirango basuzume kwangirika kw'umuhaha biturutse ku mpamvu zitandukanye, harimo imiti ikoreshwa mu kuvura kanseri, imiti imwe n'imwe, cyangwa ibintu byangiza ibidukikije. Iyi scan ishobora kugaragaza ahantu umuhaha wawe utabona umwuka uhagije cyangwa uko amaraso atembera, kabone niyo izindi igeragezwa risa nkaho risanzwe.

Ni gute Xenon-Xe-129 Hyperpolarized ikora?

Uyu mutangizi w'ishusho akora mugihe yuzuzamo umuhaha wawe umwuka ukora nk'umutangizi w'itandukaniro kuri scan ya MRI. Iyo uhumeka xenon hyperpolarized, igenda mu nzira z'umwuka wawe ikinjira mu dusaho duto tw'umwuka aho umwuka wa oxygen usanzwe uhanahanwa n'amaraso yawe.

Imiterere idasanzwe ya magnetike ya xenon itanga ibimenyetso byiza kuri scan ya MRI, mu buryo bworoshye imurikira umuhaha wawe imbere. Ibi bituma abaganga babona ntabwo gusa imiterere y'umuhaha wawe, ahubwo n'uko umwuka ugenda neza mu turere dutandukanye.

Xenon isenyuka mu buryo butagira ingaruka mu maraso yawe n'imitsi y'umuhaha, itanga andi mashusho agaragaza uko amaraso atembera n'uko umwuka uhanahanwa. Ubu bushobozi bwo gushushanya bubiri busobanura ko abaganga bashobora kubona inzira z'umwuka n'imitsi y'amaraso mu muhaha wawe icyarimwe.

Uburyo bwose bufatwa nk'ubugufi cyane ku mubiri wawe. Xenon ntikora ibikorwa bya chimique cyangwa ngo itange imbogamizi ku buryo usanzwe uhumeka. Umubiri wawe usanzwe ukuraho umwuka unyuze mu muhaha wawe mumunota muke nyuma ya scan.

Nkwiriye Gufata Nte Xenon-Xe-129 Hyperpolarized?

Mu by'ukuri ntabwo "ufata" uyu muti mu buryo busanzwe - ahubwo, uzawuhumeka mu gihe cyo gukoresha MRI yawe ukurikiranwa n'abaganga b'inzobere. Iyi nzira ibera rwose mu kigo gishinzwe gukoresha amashusho, abahanga babihuguriwe bakuyobora mu ntambwe zose.

Mbere yo gukoresha amashusho, ugomba gukuraho ibintu byose by'icyuma hanyuma ukambara ikanzu y'ibitaro. Umuhanga azasobanura amabwiriza yo guhumeka kandi ashobora kugusaba gukora imyitozo yo guhumeka mbere. Uzaryama ku meza ya MRI, hanyuma hakwegerezwa igikoresho cyo guhumekera hafi y'umunwa wawe.

Mu gihe cyo gukoresha amashusho, uzasabwa guhumeka cyane gazi ya xenon hyperpolarized ukayifata mu gihe cy'amasegonda 10-15 mugihe MRI ifata amashusho. Iyi nzira ishobora gusubirwamo inshuro nyinshi kugirango ifate amashusho atandukanye y'ibihaha byawe.

Ntabwo bisaba kwiyiriza mbere y'iyi nzira, kandi urashobora kurya bisanzwe mbere. Ariko, ugomba kwirinda caffeine mu masaha make mbere yo gukoresha amashusho yawe, kuko bishobora kugira ingaruka ku buryo uhumeka n'umuvuduko w'umutima wawe mugihe cyo gukoresha amashusho.

Nkwiriye Gufata Igihe Kingana Gite Xenon-Xe-129 Hyperpolarized?

Uyu si umuti ufata uko iminsi igenda - ukoreshwa gusa mugihe cyo gukoresha amashusho yawe ya MRI. Icyo gihe cyose cyo gukoresha amashusho gikunze kumara iminota 30-60, nubwo uzaba uhumeka xenon hyperpolarized mu gihe gito cyo gukoresha amashusho.

Uzahumeka gazi mu masegonda make gusa icyarimwe, akenshi guhumeka 3-5 bitandukanye mugihe cyo gukoresha amashusho. Hagati yo guhumeka, uzahumeka bisanzwe mugihe umuhanga ategura urukurikirane rw'amashusho akurikira.

Xenon iva mu bihaha byawe mu buryo busanzwe nyuma y'iminota mike nyuma yo guhumeka. Mugihe uva mu kigo, rwose gazi yose izaba yaravanywe mu mubiri wawe binyuze mu guhumeka bisanzwe.

Niba muganga wawe akeneye ibindi bisuzumwa, ushobora gusubira mu gihe cy'ibyumweru cyangwa amezi nyuma, bitewe n'uburwayi bwawe n'uburyo umuti wakoze.

Ni Ibihe Bikorwa Bigaragara Ku Muntu Ufata Xenon-Xe-129 Hyperpolarized?

Abantu benshi ntibagira ingaruka na zimwe zo guhumeka xenon hyperpolarized mugihe cyo gusuzumwa. Iyi gazi ntigira ubushobozi bwo guhindura imiterere y'imibiri, bivuze ko itagira icyo ikora ku bice by'umubiri wawe cyangwa ngo ibangamire imikorere isanzwe y'umubiri.

Abantu bamwe bashobora kumva bafite umutwe muke cyangwa bafite isereri nyuma yo guhagarika guhumeka, ariko ibi bikunze guterwa no guhagarika guhumeka ubwabyo aho guterwa na gazi ya xenon. Ibi byiyumvo bikunze gushira nyuma y'amasegonda make nyuma yo gusubira mu guhumeka bisanzwe.

Gake cyane, abantu bamwe bashobora kugira isesemi ryoroheje cyangwa uburyohe budasanzwe mu kanwa kabo mugihe cyo gukora iki gikorwa. Izi ngaruka ni iz'igihe gito kandi zikunze gushira vuba nyuma yo kurangiza isuzuma.

Mu bihe bidasanzwe cyane, abantu barwaye indwara zikomeye z'ibihaha bashobora guhura no kubura umwuka by'igihe gito cyangwa gukorora mugihe cyo gukora iki gikorwa. Itsinda ry'abaganga rikora isuzuma ryawe ryatojwe kumenya no gukemura ibi bibazo ako kanya.

Ibikorwa bikomeye byo kwanga xenon ntibizwi cyane kuko ari gazi idahinduka, idakunze gutera imikorere y'umubiri. Ariko, niba ufite amateka y'ibikorwa bikomeye byo kwanga izindi gazi z'ubuvuzi cyangwa ibintu bitandukanye, gerageza kumenyesha itsinda ry'abaganga mbere y'igihe.

Ninde Utagomba Gufata Xenon-Xe-129 Hyperpolarized?

Abantu benshi bashobora gukora iki gikorwa cyo gusuzuma neza, ariko hariho ibihe aho muganga wawe ashobora guhitamo uburyo bwo gusuzuma butandukanye. Abantu bafite ubwoba bukomeye bwo gufungirwa bashobora gusanga ibidukikije bya MRI bigoye, nubwo guhumeka xenon atari ikibazo.

Niba ufite ibikoresho by'icyuma byashyizwe mu mubiri nka pacemakers, ibikoresho byo mu gutwi, cyangwa ubwoko bumwe na bumwe bwa clips za aneurysm, birashoboka ko utazashobora gukorerwa isesengura rya MRI na rimwe. Muganga wawe azareba amateka yawe y'ubuvuzi n'ibikoresho byose byashyizwe mu mubiri mbere yo gutegura iyi gahunda.

Abagore batwite basanzwe birinda iri sesengura keretse bibaye ngombwa rwose, nubwo xenon ubwayo itazwiho gutera ubumuga bwo kuvuka. Icyitonderwa ni ukugabanya uburyo bwose butari ngombwa bwo kuvura mu gihe cyo gutwita.

Abantu bafite uburwayi bukomeye bwo guhumeka bakeneye ubufasha buhoraho bwa oxygen ntibashobora kuba bakwiriye gukorerwa iri sesengura. Iyi gahunda isaba guhagarika guhumeka mu gihe gito, ibyo bishobora kutazashoboka niba ufite ingorane zikomeye zo guhumeka.

Niba ufite indwara zikomeye z'umutima zituma guhagarika guhumeka bigira akaga, muganga wawe ashobora kugusaba uburyo bwo gusesengura butandukanye. Ariko, abantu benshi bafite indwara z'umutima bashobora gukorerwa iyi gahunda mu buryo bwizewe hamwe n'ubugenzuzi bukwiye.

Amazina y'ubucuruzi ya Xenon-Xe-129 Hyperpolarized

Ubu, xenon-129 hyperpolarized iboneka cyane cyane binyuze mu bigo by'ubuvuzi byihariye n'ibigo by'ubushakashatsi aho kuba ibicuruzwa by'ubucuruzi bikwirakwizwa cyane. Ibikorwa byinshi bitanga iri sesengura bikora gazi ya hyperpolarized ahantu hagaragara hakoreshwa ibikoresho byihariye.

Iyi tekiniki iracyari nshya, bityo ntuzabona iri sesengura riboneka kuri buri bitaro cyangwa ikigo gisesengura. Ibigo bikomeye by'ubuvuzi bw'amashuri makuru n'ibigo byihariye byo gusesengura ibihaha nibyo bishobora gutanga iki gikoresho cyateye imbere cyo gupima.

Uko iyi tekiniki igenda ikwirakwira, dushobora kubona imitegurire y'ubucuruzi isanzwe, ariko ubu, buri kigo gikora xenon yabo ya hyperpolarized hakurikijwe amahame akomeye y'ubuziranenge.

Uburyo bwo gusimbuza Xenon-Xe-129 Hyperpolarized

Uburyo bwinshi bwo gukoresha amashusho bushobora gutanga amakuru yerekeye imikorere y'ibihaha, nubwo nta na bumwe butanga ishusho irambuye nk'iyo MRI ya xenon ifite. Ibisuzumwa bisanzwe bya CT bishobora kugaragaza imiterere y'ibihaha ariko ntibigaragaza uko ibihaha byawe bikora neza.

Ibisuzumwa bya ventilation-perfusion (V/Q) bikoresha ibimenyetso bya radioactifs kugirango bigaragaze urujya n'uruza rw'umwuka n'amaraso mu bihaha byawe. Nubwo ibi bisuzumwa bitanga amakuru yerekeye imikorere, bikubiyemo imirasire kandi ntibitanga amakuru arambuye nk'ayo amashusho ya xenon atanga.

Ibizami byo gupima imikorere y'ibihaha bipima uko ibihaha byawe bikora neza binyuze mu kugutuma uhumeka ukoresheje ibikoresho byihariye. Ibi bizami bitanga amakuru y'agaciro yerekeye ubushobozi bw'ibihaha n'urujya n'uruza rw'umwuka ariko ntibigaragaza ahantu hari ibibazo byihariye mu bihaha byawe.

Amashusho ya helium-3 yongerewe imbaraga akora kimwe na xenon-129 ariko agakoresha gazi itandukanye. Ariko, helium-3 ihenze cyane kandi bigoye kuyibona, bituma xenon-129 iba ihitamo ryiza ku bigo byinshi by'ubuvuzi.

Ibisuzumwa bya CT bifite ubushobozi bwo hejuru hamwe n'itandukaniro bishobora kugaragaza imiterere y'ibihaha irambuye n'amakuru amwe yerekeye urujya n'uruza rw'amaraso, ariko bikubiyemo imirasire kandi ntibitanga amakuru yerekeye imikorere y'igihe nyacyo nk'ayo amashusho ya gazi yongerewe imbaraga atanga.

Ese Xenon-Xe-129 yongerewe imbaraga iruta ibizamini bisanzwe bya CT?

MRI ya xenon yongerewe imbaraga n'ibizamini bisanzwe bya CT bifite intego zitandukanye, bityo kubigereranya mu buryo butaziguye ntibiba bifite icyo bisobanura buri gihe. Ibisuzumwa bya CT birusha abandi kugaragaza imiterere y'ibihaha irambuye, kumenya ibibyimbye, no kumenya ibitagenda neza by'imiterere nk'emphysema cyangwa ibikomere.

MRI ya Xenon itanga amakuru yihariye yerekeye imikorere y'ibihaha atashobora kugaragazwa na CT. Igenda igaragaza uko ibice bitandukanye by'ibihaha byawe bihumeka neza kandi bigahinduranya gazi, ibyo bishobora kuba by'ingenzi mugusuzuma indwara zimwe na zimwe.

Ibyuma bya CT birihuta, bikaba biboneka hose, kandi bikaba byiza mu bihe by'ubutabazi aho gukora isuzuma ryihuse bikenerwa. Nanone ni byo bisanzwe bikoreshwa mu kumenya kanseri y'ibihaha, umusonga, n'ibindi bibazo by'imiterere.

Isesengura rya xenon rigaragaza ubushobozi bwarwo iyo abaganga bakeneye gusobanukirwa ibibazo by'imikorere mu bihaha byawe. Rishobora kumenya ahantu ibihaha byawe bitagikora neza kabone n'iyo bisa nk'ibisanzwe ku byuma bya CT.

Ku ndwara nyinshi z'ibihaha, ushobora gukenera ubwoko bwombi bw'isesengura kugira ngo ubone ishusho yuzuye. Muganga wawe azahitamo uburyo bwiza bwo gusesengura bushingiye ku bimenyetso byawe byihariye n'amakuru bakeneye kugira ngo bakore isuzuma ryukuri.

Ibibazo Bikunze Kubazwa Ku Bya Xenon-Xe-129 Hyperpolarized

Ese Xenon-Xe-129 Hyperpolarized iratekanye ku bantu barwaye asima?

Yego, abantu barwaye asima basanzwe bashobora gukorerwa isesengura rya hyperpolarized xenon mu buryo butekanye. Mubyukuri, iri sesengura rikoreshwa cyane cyane mu gusuzuma asima no gusobanukirwa uburyo iyi ndwara igira ingaruka ku bice bitandukanye by'ibihaha byawe.

Gasi ya xenon ubwayo ntishobora gutera ibitero bya asima kuko idahinduka mu buryo bw'imiti kandi ntishobora gutera umujinya mu nzira y'umwuka. Ariko, niba ufite asima ikomeye, idahagaze neza, muganga wawe ashobora gushaka kumenya niba ubuzima bwawe bugenda neza mbere y'igikorwa.

Ukwiye kuzana inhaler yawe yo gutabara ku gihe cyo guhura n'abaganga kandi ukamenyesha ikipe y'ubuvuzi mbere y'igihe ku byerekeye asima yawe. Bashobora kugukurikiranira hafi kandi biteguye guhangana n'ingorane zose zo guhumeka zishobora kuvuka.

Nkwiriye gukora iki niba mpanutse nkahumeka xenon-Xe-129 nyinshi cyane?

Ibi bishoboka cyane kuko xenon itangwa mu bipimo bigenzurwa neza mugihe cyo gusesengura kwa MRI yawe. Ikipe y'ubuvuzi igenzura ibintu byose byo gutanga gasi, bityo ntushobora guhumeka nyinshi cyane.

N'ubwo waba wahumeka xenon nyinshi kurusha uko byari byateganyijwe, iyi gazi ntigira uburozi kandi ivanwa mu mubiri wawe binyuze mu guhumeka bisanzwe mu minota mike. Xenon ntikwirakwira mu bice by'umubiri wawe cyangwa ngo itere ubumara.

Niba wumva utameze neza mu gihe cy'iki gikorwa, menyesha umuhanga mu by'ikoranabuhanga ako kanya. Barashobora guhagarika isesengura bakakureka guhumeka bisanzwe kugeza wumvise umeze neza.

Nkwiriye gukora iki niba ngize ikibazo cyo guhagarika guhumeka mu gihe cy'isesengura?

Ntugire impungenge niba udashoboye guhagarika guhumeka igihe cyose cyasabwaga mu gihe cy'isesengura ryawe. Itsinda ry'abaganga risobanukirwa ko hari abantu bagira ingorane zo guhagarika guhumeka, cyane cyane abafite indwara z'ibihaha.

Menyesha umuhanga mu by'ikoranabuhanga mbere y'uko isesengura ritangira ku bijyanye n'ingorane zose zo guhumeka. Barashobora guhindura uburyo bwo gushushanya kugira ngo bakore hamwe n'ubushobozi bwawe bwo guhumeka kandi bashobora gukoresha igihe gito cyo guhagarika guhumeka.

Niba ukeneye guhumeka mu gihe cy'isesengura, humeka bisanzwe. Umuhanga mu by'ikoranabuhanga ashobora gusubiramo ishusho runaka igihe witeguye, kandi igikorwa gishobora gukomeza uko ubishaka.

Nshobora gusubira mu bikorwa bisanzwe ryari nyuma yo gushushanya na Xenon-Xe-129?

Ushobora gusubira mu bikorwa byose bisanzwe ako kanya nyuma yo gusesengura kwawe kwa hyperpolarized xenon MRI. Nta mbogamizi ku gutwara imodoka, gukora, gukora imyitozo ngororamubiri, cyangwa ibindi bikorwa byose nyuma y'iki gikorwa.

Gazi ya xenon ivanwa mu mubiri wawe mu minota mike nyuma yo kurangiza isesengura, bityo nta ngaruka zirambye zashobora kubangamira gahunda yawe ya buri munsi. Ntabwo ukeneye umuntu wo kukugeza mu rugo keretse ufite izindi ndwara zisaba ubufasha.

Niba wumvise isereri rito mu gihe cy'iki gikorwa, rigomba gukira burundu mu minota mike nyuma yo kurangiza isesengura. Abantu benshi bumva bameze neza rwose igihe bahagurutse ku meza ya MRI.

Nzahabwa ryari ibisubizo byanjye bya Xenon-Xe-129 MRI?

Ibisubizo byawe bya scan bisanzwe bifata iminsi 1-3 y'akazi kugira ngo bitunganywe neza kandi bisobanurwe na radiologiste. Amashusho ya hyperpolarized xenon MRI asaba ubuhanga bwihariye kugira ngo asomwe neza, ibyo bishobora gufata igihe kirekire ugereranije na scan zisanzwe.

Muganga wawe azaguhamagara igihe ibisubizo bibonetse kugira ngo baganire ku byavuye muri scan n'intambwe zikurikira mu kwitabwaho kwawe. Ibikorwa bimwe na bimwe by'ubuvuzi bitanga imiryango yo kuri interineti aho ushobora kubona ibisubizo byawe igihe byiteguye.

Niba scan yawe yategetswe kubera impamvu zihutirwa z'ubuvuzi, radiologiste ashobora gutanga ibisubizo by'ibanze vuba. Ariko, scan nyinshi za xenon MRI zikorwa mu rwego rwo gupima indwara aho gukora mu bihe by'ubutabazi.