Zanubrutinib (inzira yo kunywa)

Brukinsa

Zanubrutinib ikoreshwa mu kuvura lymphoma ya mantle cell (MCL) mu barwayi bahabwa byibuze imiti imwe mbere yo kuvura kanseri yabo. Iyi miti kandi ikoreshwa mu kuvura Waldenström macroglobulinemia (WM). Ikoreshwa kandi mu kuvura lymphoma ya zone y'uruhande (MZL) yasubiye cyangwa itarasubiza neza imiti (refractory) mu barwayi bahabwa byibuze imiti imwe mbere (urugero, imiti ishingiye kuri anti-CD20). Iyi miti kandi ikoreshwa mu kuvura leukemiya ya chronic lymphocytic (CLL) cyangwa lymphoma nto ya lymphocytic (SLL). Zanubrutinib kandi ikoreshwa hamwe na obinutuzumab mu kuvura lymphoma ya follicular (FL) yasubiye cyangwa itarasubiza neza imiti mu barwayi bahabwa byibuze imiti ibiri mbere. Zanubrutinib ni imiti irwanya kanseri (imiti yo kuvura kanseri). Iratabara ubukura bw'uturemangingo twa kanseri, hanyuma umubiri ukabusenya. Iyi miti iboneka gusa ku rupapuro rw'umuganga. Iyi miti iboneka mu buryo bukurikira:

Mu gihe cyemezo cyo gukoresha imiti, ibyago byo gufata imiti bigomba kupimirwa ugereranyije n'akamaro izagira. Iki ni cyemezo uzatanga hamwe na muganga wawe. Kuri iyi miti, ibi bikurikira bigomba kwitabwaho: Bwira muganga wawe niba wigeze ugira uburwayi budasanzwe cyangwa ubwo kwangirika kw'umubiri kuri iyi miti cyangwa izindi miti. Nanone, bwira umuhanga mu by'ubuzima ufite andi moko y'uburwayi, nko ku biribwa, amabara, ibintu byongera ubuzima, cyangwa inyamaswa. Ku bicuruzwa bitagomba kwandikwa, soma witonze ibikoresho biri ku gipfunyika cyangwa ku kimenyetso. Ubushakashatsi bukwiye ntabwo bwakozwe ku isano y'imyaka ku ngaruka za zanubrutinib ku bana. Ubuziranenge n'ingaruka nziza ntibyarangiye. Ubushakashatsi bukwiye bwakozwe kugeza ubu ntabwo bwerekanye ibibazo byihariye by'abakuze byazagabanya ingaruka za zanubrutinib ku bakuze. Nta bushakashatsi buhagije ku bagore bwo kumenya ibyago by'uruhinja mu gihe ukoresha iyi miti mu gihe cyo konsa. Pima inyungu zishoboka ugereranyije n'ibyago bishoboka mbere yo gufata iyi miti mu gihe cyo konsa. Nubwo imiti imwe n'imwe idakwiye gukoreshwa hamwe na gato, mu bindi bihe imiti ibiri itandukanye ishobora gukoreshwa hamwe nubwo hariho ikibazo gishobora kubaho. Muri uru rubanza, muganga wawe ashobora kwifuza guhindura umwanya, cyangwa izindi ngamba zishobora kuba ngombwa. Iyo ufashe iyi miti, ni ngombwa cyane ko umuhanga mu by'ubuzima azi niba ufashe imiti iri hasi. Ibi bikurikira byatoranijwe hashingiwe ku kamaro kabyo kandi si ngombwa ko ari byose. Gukoresha iyi miti hamwe n'imiti iri hasi ntibisanzwe bisabwa, ariko bishobora kuba ngombwa mubihe bimwe na bimwe. Niba imiti yombi yandikiwe hamwe, muganga wawe ashobora guhindura umwanya cyangwa uko uyikoresha rimwe cyangwa ukoresha imiti yombi. Imiti imwe n'imwe ntigomba gukoreshwa mu gihe cyo kurya cyangwa hafi yacyo cyangwa kurya imirire imwe n'imwe kuko hariho ikibazo gishobora kubaho. Gukoresha inzoga cyangwa itabi hamwe n'imiti imwe nabyo bishobora gutera ibibazo. Ibi bikurikira byatoranijwe hashingiwe ku kamaro kabyo kandi si ngombwa ko ari byose. Gukoresha iyi miti hamwe n'ibikurikira ntibisanzwe bisabwa, ariko bishobora kuba bidashoboka mubihe bimwe na bimwe. Niba ikoreshwa hamwe, muganga wawe ashobora guhindura umwanya cyangwa uko uyikoresha iyi miti, cyangwa akaguha amabwiriza yihariye yerekeye ikoreshwa ry'ibiribwa, inzoga, cyangwa itabi. Kuba hari ibindi bibazo by'ubuzima bishobora kugira ingaruka ku ikoreshwa ry'iyi miti. Menya neza kubwira muganga wawe niba ufite ibindi bibazo by'ubuzima, cyane cyane: