Icyo Desmopressin Nasal Spray ari cyo: Ibyo ikoreshwa, urugero rwo kuyikoresha, ingaruka zayo n'ibindi

Desmopressin nasal spray ni umuti wa hormone ukorwa mu buryo bwa gihanga ufasha umubiri wawe kubika amazi igihe utari gukora hormone yayo isanzwe ya antidiuretic. Uyu muti woroshye ariko ufite akamaro ushobora kugira uruhare runini ku bantu bahanganye n'indwara nka diyabete insipidus cyangwa kunyara mu buriri, ukongera kugenzura imiterere y'amazi mu mubiri wawe mu buryo bwumvikana kandi bugenzurwa.

Desmopressin ni iki?

Desmopressin ni verisiyo yakozwe n'abantu ya hormone yitwa vasopressin umubiri wawe ukora mu buryo busanzwe mu bwonko bwawe. Iyo umubiri wawe utagize iyi hormone ihagije, ushobora gutakaza amazi menshi binyuze mu kunyara kenshi, bigatuma uhora ufite inyota kandi wumye.

Uburyo bwa nasal spray butanga iyi hormone mu buryo butaziguye binyuze mu murongo w'amazuru yawe, aho yinjirira mu maraso yawe vuba kandi neza. Tekereza nk'uko uha umubiri wawe intumwa ya chimique ikenewe kugira ngo ibwire impyiko zawe kubika amazi ahagije.

Desmopressin ikoreshwa mu iki?

Desmopressin nasal spray ivura indwara nyinshi aho umubiri wawe uhanganye no kugenzura imiterere y'amazi. Ikoreshwa cyane ni diyabete insipidus yo hagati, indwara aho ubwonko bwawe butagira hormone ihagije ya antidiuretic, bigatuma unyara cyane kandi ukagira inyota.

Nanone itangwa ku kunyara mu buriri by'ibanze, iryo rikaba ari ijambo ry'ubuvuzi ryerekeye kunyara mu buriri ku bana barengeje imyaka 6. Byongeye kandi, abaganga rimwe na rimwe barayikoresha ku ndwara zimwe zo kuva amaraso aho ishobora gufasha amaraso yawe gukora neza.

Muganga wawe ashobora no kuyigushyiriraho mu bihe by'agateganyo nko nyuma yo kubagwa ubwonko cyangwa ibikomere byo mu mutwe bigira ingaruka ku mikorere ya hormone. Buri kimwe muri ibi bikoreshwa kigamije ikibazo kimwe: gufasha umubiri wawe gucunga amazi uko bikwiye mu buryo busanzwe.

Desmopressin ikora ite?

Desmopressin ikora yigana imisemburo kamere y'umubiri wawe irwanya gukurura amazi, ikifatanya n'utunyangingo twihariye mu mpyiko zawe. Iyo ibaye, impyiko zawe zibona ikimenyetso cyo gusubiza amazi menshi mu nkari zawe, bigatuma inkari zawe ziba nyinshi kandi bigatuma udasabwa kunyara kenshi.

Ibi bifatwa nk'umuti ugamije, woroshye ukorana n'inzira zisanzwe z'umubiri wawe aho guhatira impinduka zikomeye. Ibyo bikorwa mubisanzwe bitangira mu minota 15 kugeza kuri 30 nyuma yo gukoresha spray yo mu mazuru kandi bishobora kumara amasaha 8 kugeza kuri 12, bitewe n'uko umubiri wawe wabyakiriye.

Uyu muti ukora neza cyane kuko ujya ahakenewe cyane. Iimpyiko zawe zisubiza zifata amazi ahagije, ibi bifasha gusanzura uburyo unyara kandi bigabanya inyota ikabije.

Nkwiriye gufata gute Desmopressin?

Fata spray ya desmopressin mu mazuru nk'uko muganga wawe abikwandikiye, mubisanzwe rimwe cyangwa kabiri ku munsi. Igihe cyo gufata umuti akenshi giterwa n'uburwayi bwawe bwihariye - ku burwayi bwo kunyara mu buriri, mubisanzwe uzayikoresha nimugoroba, naho ku burwayi bwa diyabete insipidus, ushobora kuyikenera mu bihe bitandukanye umunsi wose.

Mbere yo gukoresha spray, humeka mu mazuru yawe gake kugira ngo usukure ururenda urwo arirwo rwose rushobora kubangamira imitsi. Fata icupa urishyire hejuru, shyira umutwe wacyo mu zuru rimwe, ukande cyane uhumeka gake mu mazuru yawe.

Ushobora gufata uyu muti urya cyangwa utarya, nubwo abantu bamwe basanga ukora neza iyo ufashwe mu gihe kimwe buri munsi. Irinde kunywa amazi menshi mbere cyangwa nyuma yo gufata umuti, kuko ibi bishobora kugabanya imikorere yawo.

Niba ukoresha spray ku nshuro ya mbere, ushobora gukenera gutegura pompe uyikandaho inshuro nyinshi kugeza igisa n'urubura rutagaragara. Bika umuti ahantu hashyushye kandi ukurikirane umubare w'ibipimo umaze gukoresha kugira ngo umenye igihe cyo gusubiza.

Nkwiriye kumara igihe kingana iki mfata Desmopressin?

Igihe cyo kuvura na desmopressin gitandukanye cyane bitewe n'uburwayi bwawe bwihariye. Kubera diyabete insipidus, ushobora gukenera kuyikoresha igihe kirekire cyangwa ndetse ubuzima bwawe bwose, kuko iyi ndwara isanzwe itikiza yonyine.

Kubera kurara mu buriri ku bana, kuvura mubisanzwe bifata amezi 3 kugeza kuri 6 mbere na mbere, hamwe n'ibihe bya hato na hato kugirango urebe niba umwana yararenze gukenera imiti. Muganga wawe ashobora gutanga igitekerezo cyo guhagarika imiti buhoro buhoro aho guhagarara ako kanya kugirango urebe uko umubiri wawe witwara.

Niba ukoresha desmopressin kubera ibihe by'agateganyo nk'inyuma yo kubagwa cyangwa gukomereka, ushobora kuyikenera mu byumweru cyangwa amezi kugeza igihe umubiri wawe usubiranye imisemburo. Muganga wawe azakurikiza iterambere ryawe hamwe no kugenzura buri gihe kandi ahindure gahunda yo kuvura uko bikwiye.

Ni izihe ngaruka ziterwa na Desmopressin?

Abantu benshi boroherwa na desmopressin nasal spray, ariko nk'imiti iyo ariyo yose, irashobora gutera ingaruka. Kumva icyo witegura birashobora kugufasha kumva ufite icyizere cyinshi kubyerekeye kuvurwa kwawe kandi umenye igihe cyo kuvugana n'umuganga wawe.

Ingaruka zisanzwe ushobora guhura nazo zirimo gufungana mu mazuru, amazuru yiruka, cyangwa kwirata gake aho utera umuti. Izi ngaruka zaho zikunda gukira uko umubiri wawe umenyera umuti kandi ntizikunda kuba zikomeye bihagije kugirango zihagarike kuvurwa.

Abantu bamwe babona kubabara umutwe, isesemi, cyangwa kutoroherwa mu gifu, cyane cyane mugihe utangiye imiti. Ibi bimenyetso bikunda gushira muminsi mike uko umubiri wawe wimenyereza urwego rushya rwimisemburo.

Ingaruka zingenzi zo kwitondera ni ugufata amazi, bishobora gutera urwego rwo hasi rwa sodium mumaraso yawe. Ibi birashobora gutera ibimenyetso nk'umutwe, isesemi, urujijo, cyangwa umunaniro udasanzwe. Niba uhuye n'ibi bimenyetso, cyane cyane niba bikomeye cyangwa bikomeza, vugana na muganga wawe ako kanya.

Ingaruka zidakunze kubaho ariko zikomeye zirimo allergie ikaze, ishobora kugaragazwa no guhumeka bigoranye, kubyimba mu maso cyangwa mu muhogo, cyangwa ibiheri bikabije. Ibi bisaba ubufasha bwihuse bwa muganga, nubwo bitajyenda bibaho cyane iyo hakoreshejwe desmopressin yo mu mazuru.

Ninde utagomba gufata Desmopressin?

Abantu bamwe na bamwe bagomba kwirinda desmopressin yo mu mazuru kubera ibyago byiyongera byo kugira ibibazo. Niba urwaye indwara y'impyiko, guhagarara k'umutima, cyangwa ufite amateka y'urugero rwo hasi rwa sodium, uyu muti ntushobora kuba mwiza kuri wowe.

Abantu bafite ibibazo byo mu mazuru nk'ubuhumekero bukomeye, polypes zo mu mazuru, cyangwa kubagwa mu mazuru vuba aha ntibashobora kwinjiza neza umuti banyuze mu mazuru yabo. Muganga wawe ashobora kugusaba ubundi buryo bwa desmopressin cyangwa ubundi buvuzi muri ibyo bihe.

Niba utwite cyangwa wonka, ganira ku byago n'inyungu neza na muganga wawe. Nubwo desmopressin ishobora gukoreshwa mugihe cyo gutwita igihe bibaye ngombwa, bisaba gukurikiranwa neza kugirango umutekano wanyu n'umwana wanyu wese wemejwe.

Abana bari munsi y'imyaka 4 y'amavuko mubisanzwe ntibagomba gukoresha uburyo bwo mu mazuru, kuko inzira zabo zo mu mazuru zito cyane kugirango zinjize neza. Abantu bakuze bashobora gukenera doze ntoya cyangwa gukurikiranwa kenshi kubera kwiyongera kw'ubushobozi bwo kwakira ingaruka z'uyu muti.

Amazina y'ubwoko bwa Desmopressin

Desmopressin yo mu mazuru iboneka munsi y'amazina atandukanye y'ubwoko, DDAVP ikaba ariyo ikoreshwa cyane. Ushobora kandi guhura na Stimate, yateguwe byumwihariko kugirango ivure indwara zimwe na zimwe zo kuva amaraso.

Ubwoko bwa desmopressin yo mu mazuru na bwo buraboneka kandi bukora neza nkuko ubwoko bw'amazina. Umufarumasiti wawe ashobora kugufasha gusobanukirwa ubwoko bw'umuti wandikiwe kandi niba gusimbuza umuti rusange bikwiye kubera uko urugero rwawe rumeze.

Ubwanditsi butandukanye bushobora kugira ibipimo bitandukanye cyangwa uburyo bwo kubugeza, bityo ni ngombwa gukoresha ubwanditsi bumwe keretse muganga wawe abyemeye byihariye. Ibi bituma imiti ifatwa neza kandi ikagira akamaro.

Uburyo bwo gusimbura Desmopressin

Hariho ubundi buryo bwinshi bwo gusimbura niba desmopressin yo mu mazuru itagukwiriye. Imisemburo ya desmopressin itangwa mu buryo bw'ibinini, bishobora gukora neza niba ufite umwuka mubi mu mazuru cyangwa ukaba udashaka gukoresha imiti yo mu mazuru.

Kubera diyabete insipidus, ubundi buryo bwo kuvura burimo imiti ya thiazide diuretics, ishobora kugaragara nkaho itari ngombwa kuko isanzwe ikoreshwa mu kongera kunyara. Ariko, muri iyi ndwara, ishobora gufasha impyiko zawe kubika amazi neza.

Kubera kurara mu buriri, uburyo bwo kwitwara neza nk'amasaha yo gutahura ubushuhe, imyitozo yo kwitoza uruhago, no kugabanya amazi mbere yo kuryama birashobora kuba ubundi buryo bwiza cyangwa imiti yunganira. Muganga wawe ashobora kugusaba kubanza kugerageza ubu buryo cyangwa kubuhuriza hamwe n'imiti.

Mu bihe bimwe na bimwe, kuvura indwara zishingiye ku mpamvu zitera kubura imisemburo bishobora kugabanya cyangwa gukuraho icyifuzo cya desmopressin. Ibi bifitanye isano cyane niba indwara yawe yaratewe n'impamvu ivurwa nka tumor yo mu gice cy'ubwonko.

Ese Desmopressin iruta Vasopressin?

Desmopressin itanga inyungu nyinshi kurusha vasopressin isanzwe ikoreshwa mu buvuzi bwinshi. Imara igihe kirekire mu mubiri wawe, akenshi amasaha 8 kugeza kuri 12 ugereranije n'igihe gito vasopressin imara, bivuze ko imiti ifatwa gake umunsi wose.

Ubu bwoko bwa sintetike kandi bugira ingaruka nke zijyanye n'umuvuduko w'amaraso n'imikorere y'umutima. Vasopressin isanzwe ishobora gutera guhagarika imitsi y'amaraso, mugihe desmopressin yagenewe kwibanda cyane ku mikorere y'impyiko ifite ingaruka nke ku mutima.

Desmopressin iroroshye gukoresha mu rugo, cyane cyane mu buryo bwa spray yo mu mazuru, mu gihe vasopressin isanzwe isaba guterwa urushinge. Ibi bituma desmopressin ikoreshwa cyane mu kuvura indwara zirambye.

Ariko, mu bihe byihutirwa cyangwa mu buryo bwihariye bwo kuvura, abaganga bashobora guhitamo vasopressin isanzwe kubera ingaruka zayo zikomeye ku mitsi y'amaraso. Umuganga wawe azahitamo umuti ukwiriye neza ibibazo byawe by'ubuzima.

Ibibazo Bikunze Kubazwa Kuri Desmopressin

Ese Desmopressin irakwiriye abarwayi ba diyabete?

Yego, desmopressin muri rusange irakwiriye abantu barwaye diyabete mellitus (ubwoko busanzwe bwa diyabete bujyana n'isukari mu maraso). Ni ngombwa gusobanukirwa ko diyabete insipidus, ivurwa na desmopressin, itandukanye rwose na diyabete mellitus nubwo amazina asa.

Niba ufite zombi, muganga wawe azakugenzura neza kugirango arebe ko imiti itabangamirana kandi ko uburinganire bwawe bw'amazi buguma buhamye. Ikintu cy'ingenzi ni ukugirana imikoranire myiza n'ikipe yawe y'ubuzima ku bijyanye n'imiti yose ufata n'indwara ufite.

Nigira iki niba nkoresheje desmopressin nyinshi ku buryo butunganye?

Niba ukoresheje desmopressin nyinshi ku buryo butunganye, ntugahagarike umutima, ariko ubifate nk'ikintu gikomeye. Ikibazo gikomeye cyo kurenza urugero ni ugufata amazi bikaba byatera urugero rwo hasi rw'umunyu wa sodium, bishobora gutera kubabara umutwe, isesemi, urujijo, cyangwa ibibazo bikomeye.

Hagarika gukoresha umuti ako kanya uvugishe muganga wawe cyangwa ikigo gishinzwe kurwanya ubumara. Bashobora kugusaba kugabanya kunywa amazi by'agateganyo no gukurikirana ibimenyetso byawe. Mu bihe bikomeye, ushobora gukenera ibizamini by'amaraso kugirango barebe urugero rwa sodium.

Nigira iki niba nirengagije doze ya desmopressin?

Niba wibagiwe urugero, rwihutire kurufata umaze kwibuka, keretse igihe cyo gufata urugero rukurikira cyegereje. Mu gihe nk'icyo, reka urugero wibagiwe, ukomeze gahunda yawe isanzwe - ntukongere urugero rwo kwishyura urugero wibagiwe.

Kutafata urugero rimwe na rimwe mubisanzwe ntibigira ingaruka, ariko ushobora kubona ibimenyetso byawe bisubiyeho nk'ukwihagarika cyane cyangwa inyota. Niba ukunda kwibagirwa urugero, tekereza gushyiraho ibyibutso kuri terefone yawe cyangwa ukoreshe agasanduku k'imiti kugirango bigufashe gukurikiza gahunda.

Ni ryari nshobora kureka gufata Desmopressin?

Ntuzigere uhagarika gufata desmopressin ako kanya utabanje kuvugana na muganga wawe. Igihe cyo guhagarika giterwa rwose n'uburwayi bwawe bw'ibanze n'uburyo urimo kwitwara neza ku miti.

Kubera indwara z'igihe gito, muganga wawe azagabanya buhoro buhoro urugero rwawe cyangwa agushyireho ibihe byo kugerageza kureka imiti kugirango arebe niba umubiri wawe wasubiye gukora imisemburo. Kubera indwara zidakira nka diyabete insipidus ihoraho, ushobora gukenera kuvurwa ubuzima bwawe bwose, ariko ibyo ntibisobanura ko udashobora kubaho ubuzima bwuzuye kandi bufite imbaraga.

Nshobora kugenda n'umuti wa Desmopressin mu mazuru?

Yego, urashobora kugenda n'umuti wa desmopressin mu mazuru, ariko uzakenera gutegura mbere. Bika umuti mu gikoresho cyawo cy'umwimerere cyanditseho amazina yawo kandi uwupakishe mu gikapu cyawe cyo mu ntoki kugirango wirinde ubushyuhe burenze urugero mu gikapu cyagenewe gutwarwa.

Tekereza kuzana ibaruwa ivuye kwa muganga wawe isobanura impamvu yawe y'ubuvuzi yo gukoresha umuti, cyane cyane ku ngendo mpuzamahanga. Pakisha imiti yinyongera mu gihe cyo gutinda, kandi ukore ubushakashatsi niba igihugu ugiye kigira imbogamizi ku kwinjiza imiti yandikiwe na muganga.