Icyo Deutetrabenazine ari cyo: Ibikoreshwa, Urutonde rw'imiti, Ingaruka ziterwa n'iyo miti n'ibindi

Deutetrabenazine ni umuti wandikirwa na muganga ufasha kugenzura imyitwarire idashimishije mu bantu bafite indwara zimwe na zimwe zo mu bwonko. Ukora ugabanya buhoro buhoro imikorere y'imiti yihariye yo mu bwonko ishobora gutera imitsi idashaka kwikorera, itanga icyizere kandi ikongera ubuzima bwiza kubafite ibibazo byo kwikorera.

Deutetrabenazine ni iki?

Deutetrabenazine ni umwe mu miti yitwa VMAT2 inhibitors. Tekereza nk'uburyo bwo guhagarika buhoro buhoro ubwonko bwawe bugenzura imyitwarire. Uyu muti ufasha kugenzura dopamine, umuti wo mu bwonko ugira uruhare runini mu kugenzura imitsi.

Uyu muti wagenewe by'umwihariko kumara igihe kirekire kandi ugatuma habaho ingaruka nke ugereranije n'indi miti isa n'iyi yari isanzweho. Ifatirwa mu kanwa mu buryo bw'ibinini kandi bisaba gukurikiranwa neza na muganga wawe kugirango abone urugero rukwiye rw'imiti rukenewe kubibazo byawe byihariye.

Deutetrabenazine ikoreshwa mu iki?

Deutetrabenazine ikoreshwa cyane cyane kubibazo bibiri bikomeye bitera imyitwarire idashakaga. Muganga wawe ashobora kugusaba uyu muti niba ufite chorea ijyanye n'indwara ya Huntington cyangwa tardive dyskinesia.

Indwara ya Huntington chorea ikubiyemo imyitwarire idasanzwe, idahanitse ishobora kugira ingaruka ku maboko yawe, amaguru, mu maso, n'umubiri. Iyi myitwarire akenshi igaragara cyane iyo uri mu gihe cy'umunabi cyangwa ugerageza kwitonda. Deutetrabenazine irashobora gufasha kugabanya ubukana bw'iyi myitwarire, bigatuma imirimo ya buri munsi icungwa neza.

Tardive dyskinesia ikunda gutera nyuma yo gukoresha imiti imwe na rimwe yo mu mutwe igihe kirekire. Iyi ndwara itera imyitwarire isubiramo, idashaka, akenshi igira ingaruka kumaso, ururimi, n'umushyi. Ushobora kubona iminwa ishakisha, ururimi rurasa, cyangwa mu maso hazana iminkanyari udashobora kugenzura.

Deutetrabenazine ikora ite?

Deutetrabenazine ikora ibi ikingira poroteyine yitwa VMAT2 mu bwonko bwawe. Iyi poroteyine niyo ishinzwe gupakira dopamine mu duce twabugenewe two kubikamo muri selile z'imitsi. Mugukingira imikorere ya dopamine mu duce twihariye tw'ubwonko, umuti ufasha gutuza ibimenyetso byo kwivumbagatanya.

Uyu muti ufatwa nk'umuti ufite imbaraga ziringaniye kandi bisaba guhindura urugero rwawo buhoro buhoro. Muganga wawe azagutangirira ku rugero ruto hanyuma akaruzamura buhoro buhoro mu byumweru byinshi. Ubu buryo bwitondewe bufasha umubiri wawe kumenyera kandi bugabanya ingaruka zishobora kubaho.

Uyu muti ntukiza indwara yihishe ariko utanga ubufasha bukomeye ku bimenyetso. Abantu benshi babona impinduka nziza mu mikorere yabo mu gihe gito nyuma yo gutangira kuvurwa, nubwo inyungu zose zishobora gutwara amezi menshi kugirango zigaragare.

Nkwiriye Gufata Uyu Muti Wa Deutetrabenazine Nte?

Fata deutetrabenazine nkuko byategetswe na muganga wawe, akenshi kabiri ku munsi hamwe n'ibiryo. Kuwufata hamwe n'ibiryo bifasha umubiri wawe kwinjiza neza umuti kandi bigabanya amahirwe yo kurwara mu gifu. Urashobora kuwufata hamwe n'ubwoko bwose bw'ibiryo, ariko guhora ufata umuti ku gihe bifasha kugumana urugero ruzigama mu mubiri wawe.

Mimina ibinini byose hamwe n'ikirahure kinini cy'amazi. Ntukoreshe ibinini, ntuzimene, cyangwa ngo ubice, kuko ibi bishobora kugira ingaruka ku buryo umuti usohoka mu mubiri wawe. Niba ugira ikibazo cyo kumira ibinini, ganira na farumasiye wawe kuri ubundi buryo.

Muganga wawe azagutangirira ku rugero ruto hanyuma arwongere buhoro buhoro buri cyumweru cyangwa bibiri. Uku kwiyongera gake bifasha umubiri wawe kumenyera kandi bituma ikipe yawe y'ubuzima ikurikirana ingaruka zose zishobora kubaho. Ntukigere uhindura urugero rwawe wenyine, kabone niyo wumva umuti utagikora neza nkuko byari byitezwe.

Nkwiriye Kumara Igihe Kingana Gite Ndafa Deutetrabenazine?

Deutetrabenazine akenshi ni imiti ifatwa igihe kirekire ushobora kumara amezi cyangwa imyaka uyifata. Igihe uyimarana giterwa n'uburwayi bwawe n'uburyo umubiri wawe wakiriye imiti. Muganga wawe azajya agenzura buri gihe niba inyungu zo kuyifata zikiri nyinshi kurusha ingaruka zishobora kubaho.

Ku ndwara ya Huntington, ushobora kumara imyaka myinshi ufata iyi miti uko uburwayi bugenda bwiyongera. Muganga wawe azajya ahindura urugero rw'imiti ufata uko ibimenyetso byawe bigenda bihinduka ndetse n'uko ubuzima bwawe muri rusange bumeze. Kugenzura buri gihe bifasha kumenya niba imiti ikora neza kandi itagutera ibibazo.

Niba urwaye tardive dyskinesia, igihe uzamara uvurwa gishobora gutandukana. Abantu bamwe babona ibimenyetso byabo bigenda bikira uko igihe kigenda gihita, bashobora kugabanya urugero rw'imiti bafata cyangwa bakayireka burundu bayobowe na muganga. Ntukigere ureka gufata deutetrabenazine ako kanya, kuko ibyo bishobora gutuma ibimenyetso byawe bisubira cyangwa bikiyongera.

Ni izihe ngaruka ziterwa na Deutetrabenazine?

Kimwe n'indi miti yose, deutetrabenazine ishobora gutera ingaruka, nubwo abantu benshi bayihanganira neza. Kumenya ibyo witegura bishobora kugufasha kwitegura neza no kumenya igihe wakwegera umuganga wawe.

Ingaruka zisanzwe zikunze kuba nto kandi akenshi zigenda zikira uko umubiri wawe umenyera imiti:

• Gusinzira cyane cyangwa kunanirwa
• Impiswi cyangwa isesemi
• Umunwa wumye
• Kugorwa no gusinzira
• Guhora uhangayitse cyangwa kudatuza

Izi ngaruka zisanzwe zikunze kugabanuka nyuma y'ibyumweru bike uvurwa. Kunywa amazi ahagije, kurya neza, no kugira akamenyero keza ko gusinzira bishobora kugufasha kugabanya izi ngaruka.

Abantu bamwe bashobora kugira ingaruka zikomeye zisaba ubufasha bwihuse bwa muganga. Izi zikubiyemo ibimenyetso byo kwiheba, gutekereza kwigirira nabi, gusinzira cyane bikabuza gukora imirimo ya buri munsi, cyangwa ibibazo bishya byo kwigendera nk'umubiri ugoye cyangwa guhinda umushyitsi.

Mu buryo butajegajega, deutetrabenazine irashobora gutera indwara ikomeye yitwa neuroleptic malignant syndrome. Ibi bikubiyemo umuriro mwinshi, gukakara kw'imitsi, urujijo, n'imihindagurikire y'umuvuduko w'umutima cyangwa umuvuduko w'amaraso. Nubwo bitajegajega, ibi bisaba ubuvuzi bwihutirwa niba bibaye.

Ninde Utagomba Gufata Deutetrabenazine?

Abantu bamwe na bamwe bagomba kwirinda deutetrabenazine kubera ibyago byiyongera by'ingorane zikomeye. Muganga wawe azasuzuma neza amateka yawe y'ubuvuzi mbere yo kwandika uyu muti kugirango yemeze ko ari mwiza kuri wewe.

Ntabwo ugomba gufata deutetrabenazine niba ufite ibibazo bikomeye by'umwijima, kuko umubiri wawe ushobora kutabasha gutunganya neza uyu muti. Abantu bafite amateka yo kwiheba cyangwa ibitekerezo byo kwiyahura bakeneye kwitabwaho by'umwihariko, kuko uyu muti ushobora gukomeza ibi bibazo kuri bamwe.

Niba ufata imiti imwe na rimwe, deutetrabenazine irashobora kutagukwira. Ibi bikubiyemo MAO inhibitors, imiti imwe yo kurwanya depression, n'imiti ishobora gutera umuvuduko w'umutima utajegajega. Umuganga wawe n'umuganga bazasuzuma imiti yawe yose iriho kugirango barebe niba hariho uburyo bwo guhura.

Abagore batwite cyangwa bonka bagomba kuganira ku byago n'inyungu neza n'umuganga wabo. Nubwo uyu muti utarigishwaho cyane mu gihe cyo gutwita, muganga wawe ashobora kuwugusaba niba inyungu ziruta ibyago bishobora kugutera wowe n'umwana wawe.

Amazina ya Deutetrabenazine

Deutetrabenazine iboneka munsi y'izina ry'ubucuruzi rya Austedo muri Leta Zunze Ubumwe z'Amerika. Iyi niyo miterere isanzwe yandikwa y'uyu muti kandi iza mumbaraga zitandukanye za tablet kugirango byorohereze gupima neza.

Ibihugu bimwe na bimwe bishobora kugira amazina atandukanye y'ubucuruzi cyangwa verisiyo rusange zihari. Buri gihe jya ureba umuganga wawe kugirango wemeze ko wakira umuti ukwiye, cyane cyane niba ujya mu rugendo cyangwa wimukira ahandi.

Uburyo bwo gusimbuza Deutetrabenazine

Niba deutetrabenazine itagukwiriye, hari izindi nshuti zishobora kugufasha mu gucunga ibimenyetso byo kurwara kwawe. Muganga wawe azareba uko urwaye, amateka yawe y'ubuzima, n'intego zawe zo kuvurwa igihe ashaka izindi nzira.

Ku ndwara ya Huntington chorea, tetrabenazine ni umuti usanzwe ukora kimwe ariko ushobora gutera ingaruka nyinshi. Abantu bamwe kandi bafashwa n'imiti irwanya ubwonko nka haloperidol cyangwa risperidone, nubwo ibi bifite ibyago byabyo n'inyungu zabyo.

Tardive dyskinesia nayo irashobora kuvurwa na valbenazine, undi muti wa VMAT2 uhwanye na deutetrabenazine. Abantu bamwe babona intsinzi hamwe n'inyongera ya vitamine E cyangwa guhindurira ku miti itandukanye ya psychiatrique idashobora gutera ibibazo byo kwimuka.

Uburyo butari ubw'imiti nka physiothérapie, thérapie occupationnelle, na thérapie y'imvugo birashobora gufasha imiti iyo ariyo yose. Ubu buvuzi bugufasha gukora ingamba zo gucunga ibimenyetso no gukomeza ubwigenge bwawe mu bikorwa bya buri munsi.

Ese Deutetrabenazine iruta Tetrabenazine?

Deutetrabenazine itanga inyungu nyinshi kurusha tetrabenazine, nubwo imiti yombi ikora kimwe. Itandukaniro rikuru riri mu buryo ugomba kuyifata kenshi n'ingaruka zayo.

Deutetrabenazine mubisanzwe isaba gusa gufata kabiri ku munsi, mugihe tetrabenazine akenshi igomba gufatwa gatatu ku munsi. Iyi gahunda yoroshye irashobora koroshya kwibuka umuti wawe no gukomeza urwego rwo hejuru mu mubiri wawe umunsi wose.

Abantu benshi bahura n'ingaruka nkeya hamwe na deutetrabenazine, cyane cyane gusinzira gukabije no kwiheba. Uyu muti kandi ntushobora gutera igabanuka rikomeye ry'umuvuduko w'amaraso igihe uhagurutse vuba. Ariko, ibisubizo by'umuntu ku giti cye biratandukanye, kandi abantu bamwe baracyakora neza kuri tetrabenazine.

Umuganga wawe azatekereza ku bimenyetso byawe byihariye, imibereho yawe, n'amateka yawe y'ubuvuzi mugihe ahitamo hagati y'iyo miti. Uburyo "bwiza" buterwa rwose n'uko buri muti ukora neza kubibazo byawe byihariye n'ingaruka z'uruhande ushobora kwihanganira neza.

Ibikunze Kubazwa Kuri Deutetrabenazine

Ese Deutetrabenazine iratekanye kubafite indwara z'umutima?

Deutetrabenazine irashobora gukoreshwa neza kubantu benshi bafite indwara z'umutima, ariko bisaba gukurikiranwa neza. Uyu muti rimwe na rimwe ushobora kugira ingaruka kumutima, bityo umuganga wawe ashobora gupima imikorere yumutima wawe mbere yo gutangira kuvura no mu gihe cyo kuvurwa.

Niba ufite amateka y'umutima utagenda neza cyangwa ufata imiti y'indwara z'umutima, umuganga wawe ashobora gutegeka electrocardiogram (EKG) kugirango arebe imikorere y'amashanyarazi yumutima wawe. Ibi bifasha kumenya neza ko uyu muti utazagira ingaruka mbi kumutima wawe cyangwa indi miti y'umutima.

Nigute nzakora niba mfashe Deutetrabenazine nyinshi kubwimpanuka?

Niba ufata Deutetrabenazine nyinshi kubwimpanuka kuruta uko byategetswe, vugana numuganga wawe cyangwa ikigo gishinzwe kugenzura uburozi ako kanya. Gufata nyinshi bishobora gutera ibitotsi bikabije, urujijo, imitsi ikomeye, cyangwa ibibazo byo guhumeka bisaba ubufasha bw'ubuvuzi.

Ntugerageze kwivugisha cyangwa gufata indi miti kugirango urwanye uburozi. Ahubwo, shakisha ubufasha bw'ubuvuzi ako kanya, cyane cyane niba wumva uruhutse cyane, ufite ibibazo byo guhumeka, cyangwa ufite imitsi ikomeye. Zana icupa ry'imiti yawe kugirango ufashishe abaganga gusobanukirwa neza icyo wafashe n'ingano yacyo.

Nigute nzakora niba nciwe doze ya Deutetrabenazine?

Niba ucikanwa na doze, yifate ako kanya wibuka, keretse niba hafi ya doze yawe iteganyijwe. Niba hashize amasaha arenga 6 kuva doze yawe yabuze kandi uri mumasaha make ya doze yawe ikurikira, reka doze yabuze ukomeze gahunda yawe isanzwe.

Ntugasuzume imiti ibiri icyarimwe kugira ngo usimbure urugero rwasibye, kuko ibyo bishobora kongera ibyago byo kugira ingaruka zidakunzwe. Niba ukunda kwibagirwa urugero, tekereza gushyiraho alarme kuri terefone cyangwa gukoresha umuteguro w'imiti kugira ngo ugufashe kwibuka gahunda yawe y'imiti.

Ni ryari nshobora guhagarika gufata Deutetrabenazine?

Ntuzahagarike gufata deutetrabenazine ako kanya utabanje kuvugana na muganga wawe. Guhagarika ako kanya bishobora gutuma ibimenyetso byawe byo kugenda bisubira vuba kandi bishobora kuba bikomeye kurusha mbere yo gutangira kuvurwa.

Muganga wawe azagufasha kugabanya buhoro buhoro urugero rwawe mu byumweru byinshi niba ukeneye guhagarika umuti. Ubu buryo bwo kugabanya buhoro buhoro butuma umubiri wawe uhinduka kandi bufasha kwirinda ibimenyetso byo gukurwaho cyangwa gusubira ako kanya kw'ibimenyetso byawe byo guhungabana.

Nshobora kunywa inzoga nkanwa nka Deutetrabenazine?

Nibyiza kwirinda inzoga mugihe ufata deutetrabenazine, kuko ibintu byombi bishobora gutera gusinzira no kugira ingaruka ku mikoranire yawe. Kubihuza bishobora kongera ibyago byo kugwa, impanuka, no gusinzira cyane bishobora kuba biteje akaga.

Niba uhisemo kunywa rimwe na rimwe, wikwiriza ku bwinshi buto kandi witondere uko wumva. Ntukigere utwara imodoka cyangwa ukoresha imashini nyuma yo kunywa mugihe ufata uyu muti, kandi buri gihe uvugane ukuri n'umuganga wawe kubyerekeye kunywa inzoga kugirango bashobore kugukurikirana neza.