Icyo Dofetilide ari cyo: Ibikoreshwa, Uburyo bwo kuyifata, Ingaruka zayo n'ibindi

Dofetilide ni umuti wandikirwa n'abaganga uvura umutima ufasha gusubiza no gukomeza umuvuduko usanzwe w'umutima ku bantu bafite uburwayi bw'umutima butajegajega. Uyu muti ubarizwa mu cyiciro cy'imiti yitwa antiarrhythmic, ikora igihe igize ingaruka ku bimenyetso by'amashanyarazi mu mutima wawe kugira ngo ifashe gutera mu buryo buhoraho kandi busanzwe.

Niba muganga wawe yaraguhaye dofetilide, birashoboka ko ufite uburwayi bwa atrial fibrillation cyangwa atrial flutter. Ibi ni indwara zisanzwe z'umutima aho ibice byo hejuru by'umutima wawe biterana mu buryo butajegajega cyangwa vuba cyane, bishobora gutuma wumva unaniwe, ufite umwuka muke, cyangwa bigatera kutumva neza mu gituza.

Dofetilide ikoreshwa mu kuvura iki?

Dofetilide yandikirwa by'umwihariko kuvura ibibazo bibiri by'ingenzi by'umutima: atrial fibrillation na atrial flutter. Izi ndwara zibaho iyo ibimenyetso by'amashanyarazi mu bice byo hejuru by'umutima wawe bitunganye nabi, bigatuma umutima wawe utera mu buryo butajegajega cyangwa vuba cyane.

Muganga wawe ashobora kugutera dofetilide kugira ngo asubize umuvuduko w'umutima wawe utajegajega mu buryo busanzwe, uburyo bwo kuvura buzwi nka cardioversion. Uyu muti kandi ushobora gufasha gukomeza uwo muvuduko usanzwe umaze gusubizwa, ukabuza imiterere itajegajega gusubira.

Uyu muti akenshi ugenewe abantu batitabiriye neza imiti yindi ivura umutima cyangwa igihe izindi nshuti zitabereye. Umuganga w'umutima wawe azasuzuma neza niba dofetilide ari wo muti ukwiriye kuri wowe.

Dofetilide ikora ite?

Dofetilide ikora ibara ibice by'amashanyarazi byihariye mu ngirangingo z'umutima wawe byitwa imiyoboro ya potasiyumu. Tekereza kuri iyi miyoboro nk'inzira zigenzura urujya n'uruza rw'ibimenyetso by'amashanyarazi binyuze mu mikaya y'umutima wawe.

Mugufunga izo nzira, dofetilide ituma imikorere y'amashanyarazi mu byumba byo hejuru by'umutima wawe itinda kandi igashyirwa mu buryo. Ibi bifasha gusubiza ishusho y'amashanyarazi ihuzagurwa umutima wawe ukeneye kugira ngo utere ku buryo buhoraho kandi neza.

Iyi ni imiti ikomeye isaba gukurikiranwa neza. Ingaruka ku mikorere y'amashanyarazi y'umutima wawe ni zikomeye, ni yo mpamvu muganga wawe azashaka kukugenzura neza igihe utangiye ubu buvuzi.

Nkwiriye Gufata Dofetilide Nte?

Dofetilide iza mu buryo bw'ibikoresho ufata unywa mu kanwa, akenshi kabiri ku munsi mu gihe gihwanye. Muganga wawe azagena gahunda nyayo yo gufata imiti bitewe n'imikorere y'impyiko zawe n'uburwayi bw'umutima wawe.

Ushobora gufata dofetilide hamwe n'ibiryo cyangwa utabifite, ariko gerageza kuyifata mu buryo bumwe buri gihe kugira ngo bigende neza. Mimina ibikoresho byose hamwe n'ikirahure cyuzuye cy'amazi. Ntugasenya, ntukore, cyangwa ufungure ibikoresho, kuko ibi bishobora kugira ingaruka ku buryo imiti yinjira.

Gufata imiti yawe mu gihe kimwe buri munsi bifasha kugumana urwego rwawo ruzigama mu mubiri wawe. Abantu benshi babona ko bifasha gushyiraho ibyibutso kuri terefone cyangwa gufata imiti yabo hamwe n'ibikorwa bya buri munsi nk'amafunguro.

Igihe utangira dofetilide, bizakenerwa ko urara mu bitaro byibuze iminsi itatu. Ibi bituma ikipe yawe y'ubuvuzi igenzura umuvuduko w'umutima wawe kandi igahindura urugero rwawe mu buryo bwizewe uko umubiri wawe wimenyereza imiti.

Nkwiriye Gufata Dofetilide Igihe Kingana Gite?

Igihe cyo kuvura na dofetilide gitandukanye cyane ku muntu ku muntu, bitewe n'uburwayi bw'umutima wawe bwihariye n'uburyo wemera imiti. Abantu bamwe bashobora kuyikeneyeho amezi menshi, mu gihe abandi bashobora kuyifata imyaka myinshi.

Muganga wawe azagenzura buri gihe niba imiti ikikenewe kandi ikora neza kuri wewe. Bazatekereza ibintu nk'uburyo umuvuduko w'umutima wawe ucungwa neza, ingaruka zose ubona, n'impinduka mu buzima bwawe muri rusange.

Ntugasubize gukoresha dofetilide mu buryo butunguranye utabanje kubivugana na muganga wawe. Kubihagarika mu buryo butunguranye bishobora gutuma umutima wawe utongera gukora neza, bishobora gutera ibibazo bikomeye. Muganga wawe azagutegurira gahunda nziza niba ukeneye guhagarika imiti.

Mbese ni izihe ngaruka ziterwa na Dofetilide?

Kimwe n'indi miti yose, dofetilide ishobora gutera ingaruka, nubwo atari buri wese uzagira izo ngaruka. Kumenya ibyo ugomba kwitaho bifasha kuguma mu mutekano no kuvugana neza n'ikipe yawe y'ubuvuzi.

Ikibazo gikomeye cyane kuri dofetilide ni umuvuduko w'umutima ushobora guteza akaga witwa torsades de pointes. Iyi ni yo mpamvu uzagenzurwa cyane iyo utangiye gufata umuti no mu gihe cyo guhindura urugero rwawo.

Ingaruka zisanzwe abantu benshi bahura nazo zirimo:

• Umutwe
• Urubavu cyangwa kutumva neza mu gituza
• Urugero cyangwa kumva urushye
• Isesemi cyangwa kuribwa mu nda
• Kugira umunaniro cyangwa intege nke
• Kugufiwa umwuka
• Ibimenyetso by'indwara y'ibicurane

Ibi bimenyetso mubisanzwe ntibikomeye kandi bishobora kuzanzamuka uko umubiri wawe wimenyereza umuti. Ariko, ugomba guhora utangariza muganga wawe ibimenyetso bishya cyangwa bikomeza.

Ingaruka zikomeye zisaba ubufasha bwihuse bw'abaganga zirimo:

• Urugero rukabije cyangwa guta ubwenge
• Umutima utera cyane cyangwa utagenda neza
• Urubavu rukabije
• Kugorwa no guhumeka
• Kubyimba amaguru, ibibero, cyangwa ibirenge
• Kugira umunaniro cyangwa intege nke bidasanzwe

Niba ubonye kimwe muri ibi bimenyetso, vugana na muganga wawe ako kanya cyangwa ushake ubufasha bwihutirwa bw'ubuvuzi. Ibi bishobora kuba ibimenyetso by'ikibazo gikomeye cy'umutima gikeneye kuvurwa vuba.

Ninde utagomba gufata Dofetilide?

Dofetilide ntikoreshwa kuri buri wese, kandi hari ibintu byinshi by'ingenzi n'ibihe uyu muti utagomba gukoreshwa. Muganga wawe azasuzuma neza amateka yawe y'ubuvuzi mbere yo kuwandikira.

Ntabwo ugomba gufata dofetilide niba ufite indwara ikomeye y'impyiko cyangwa niba impyiko zawe zitagikora neza. Kubera ko impyiko zawe zikura uyu muti mu mubiri wawe, imikorere mibi y'impyiko irashobora gutuma urwego rw'uyu muti ruzamuka mu buryo buteye akaga.

Abantu bafite indwara zimwe na zimwe z'umutima bagomba kwirinda dofetilide, harimo abafite:

• QT igihe kirekire kuri ECG yabo
• Kunanirwa k'umutima gukomeye
• Gufunga umutima wuzuye nta pacemaker
• Ubwoko bumwe na bumwe bw'indwara zo mu mutima

Byongeye kandi, dofetilide irashobora gukorana n'indi miti myinshi mu buryo buteye akaga. Ntabwo ugomba kuyifata niba ukoresha imiti imwe na mikorobe, imiti irwanya imyungu, cyangwa indi miti igira ingaruka ku mutima.

Abagore batwite cyangwa bonka bagomba kuganira ku byago n'inyungu na muganga wabo, kuko umutekano wa dofetilide mugihe cyo gutwita utarashimangirwa neza.

Amazina ya Dofetilide

Dofetilide iboneka munsi y'izina ry'ubucuruzi rya Tikosyn muri Leta Zunze Ubumwe z'Amerika. Iyi ni yo miti isanzwe yandikwa cyane.

Kugeza ubu, nta miti ya dofetilide iboneka ku isoko rya Amerika. Ibi bivuze ko ushobora guhabwa umuti w'izina ry'ubucuruzi iyo umuti wawe wanditswe.

Buri gihe menya neza ko farumasi yawe ikugezaho umuti nyawo muganga wawe yaguhaye. Niba ufite ibibazo bijyanye n'umuti wakiriye, ntugatinye kubaza umufarumasiti wawe ibisobanuro.

Uburyo bwo gusimbuza Dofetilide

Niba dofetilide itagukwiriye cyangwa idakora neza, muganga wawe afite izindi nzira nyinshi zo gufasha kugenzura umuvuduko w'umutima wawe. Guhitamo biterwa n'uburwayi bwawe bwihariye, izindi ngorane z'ubuzima, n'uburyo witwaye ku miti yakoreshejwe mbere.

Iindi miti irwanya arrhythmia ishobora kwitabwaho harimo amiodarone, flecainide, propafenone, na sotalol. Buri imwe muri iyi ikora mu buryo butandukanye kandi ifite inyungu zayo n'ingaruka zishobora guteza.

Ubuvuzi butakoresha imiti burahari kandi ku bantu bamwe. Ibi bishobora kuba harimo electrical cardioversion, aho umuriro wagenzurwa usubiza umutima mu murongo usanzwe, cyangwa catheter ablation, uburyo bwo kwangiza uduce duto tw'umutima dutera umutima kudatera neza.

Umuvuzi w'umutima wawe azakorana nawe kugirango abone uburyo bwiza bwo kuvura bushingiye ku miterere yawe bwite, yita ku bintu nk'imyaka yawe, ubuzima bwawe muri rusange, n'ibyo ukunda mu buvuzi.

Ese Dofetilide iruta Amiodarone?

Zose uko ari ebyiri, dofetilide na amiodarone ni imiti ikora neza mu kuvura umutima udatera neza, ariko zikora mu buryo butandukanye kandi zifite inyungu n'ibibi byazo. Nta na rimwe riruta irindi.

Dofetilide ikunda kugira ingaruka nke zirambye zikora ku ngingo nk'ibihaha, umwijima, na tiroyide, ibyo bishobora kuba impungenge kuri amiodarone. Ariko, dofetilide isaba gukurikiranwa neza kw'imikorere y'impyiko kandi ishobora gutangirwa mu bitaro gusa.

Amiodarone akenshi ikora neza ku bwoko bumwe bw'ibibazo by'umutima udatera neza kandi ishobora gukoreshwa ku bantu bafite ibibazo by'umutima bikomeye. Ariko, ishobora gutera ingaruka zirambye zikomeye, cyane cyane iyo ikoreshejwe igihe kirekire.

Umuvuzi w'umutima wawe azatekereza ku bibazo by'umutima wawe, imikorere y'impyiko, imiti yindi, n'ubuzima bwawe muri rusange mugihe ahitamo hagati y'izi mpuzamiti. Umuti

Niba ufite uburwayi bukomeye bw'umutima, dofetilide ntibisanzwe byemewe kuko bishobora kongera uburwayi bwawe. Muganga w'umutima wawe azareba imikorere y'umutima wawe, bipimwa n'ibizamini nk'echocardiogram, mbere yo kwandika uyu muti.

Nkwiriye gukora iki niba nanyweye dofetilide nyinshi bitunguranye?

Niba utunguranye ukanywa dofetilide nyinshi kuruta uko byanditswe, vugana n'umuganga wawe ako kanya cyangwa ujye mu cyumba cy'ubutabazi kiri hafi. Kunywa nyinshi bishobora gutera ibibazo by'umuvuduko w'umutima bidasanzwe bisaba ubufasha bwihuse bw'abaganga.

Ntugategereze ngo urebe niba wumva umeze neza. Kunywa dofetilide nyinshi bishobora gutera ibibazo bikomeye by'umuvuduko w'umutima bishobora kutagaragaza ibimenyetso mbere na mbere ariko bishobora kuba byateza akaga. Zana urupapuro rw'imiti yawe kugira ngo abaganga babone neza icyo wanyoye n'ingano yacyo.

Nkwiriye gukora iki niba nirengagije kunywa dofetilide?

Niba wirengagije kunywa dofetilide, yinywere ako kanya wibuka, keretse igihe cyo kunywa doze ikurikira kigeze. Muri icyo gihe, reka doze wirengagije unywe doze ikurikira ku gihe cyayo gisanzwe.

Ntunywe doze ebyiri icyarimwe kugira ngo usimbure doze wirengagije, kuko ibyo bishobora kongera ibyago byo kugira ingaruka zikomeye. Niba utazi neza igihe cyangwa wirengagije doze nyinshi, vugana n'umuganga wawe cyangwa umufarumasiti kugira ngo bagufashe.

Nshobora kureka kunywa dofetilide ryari?

Ukwiye kureka kunywa dofetilide gusa ubikore ubisabwe n'umuganga wawe. Muganga w'umutima wawe azagena igihe byemewe guhagarika umuti bitewe n'umuvuduko w'umutima wawe, ubuzima bwawe muri rusange, n'uburyo wakiriyeho ubuvuzi.

Abantu bamwe bashobora kureka kunywa dofetilide nyuma y'uko umuvuduko w'umutima wabo umaze igihe gito utajegajega, mu gihe abandi bashobora gukenera gukomeza kuyinywa igihe kirekire. Umuganga wawe azategura gahunda nziza yo guhagarika umuti niba utakigikenewe.

Nshobora kunywa inzoga nkanwa dofetilide?

Ni byiza kugabanya kunywa inzoga igihe urimo gufata dofetilide, kuko inzoga ishobora kugira ingaruka ku mutima wawe kandi ikaba yagira uruhare mu mikoranire y'imiti. Ganira n'umuganga wawe ku bijyanye no kunywa inzoga kugira ngo umenye icyo bikugendaho.

Inzoga kandi ishobora gutuma ibimenyetso bimwe na bimwe byo ku ruhande bya dofetilide birushaho kuba bibi, nk'izunguruka cyangwa kumva umutwe. Niba uhisemo kunywa, bikore mu rugero kandi umenye uko wumva, cyane cyane igihe utangiye gufata umuti.