Icyo Dronabinol Aricyo: Ibyo Ikoreshwa, Uburyo Bwo Kuyifata, Ingaruka Zayo n'Ibindi

Dronabinol ni ubwoko bwa THC bwakozwe mu buryo bwa gihanga, ikintu gikora kiboneka muri marijuwana, cyemejwe na FDA nk'umuti wandikirwa. Iza mu buryo bw'ibinini kandi ikoreshwa mu gufasha abantu gucunga indwara zihariye nk'isuka ikabije iterwa na chimiothérapie no gutakaza ubushake bwo kurya mu bihe runaka.

Uyu muti ukora mu buryo butandukanye na marijuwana ikoreshwa mu birori kuko ikorwa neza, igipimo cyayo giteganijwe neza, kandi ikandikwa na muganga ku mpamvu z'ubuvuzi zihariye. Tekereza nk'uko ufata ibice bifasha bya cannabis ukabihindura uburyo bwo kuvura bugenzurwa kandi bwo mu buvuzi.

Dronabinol ni iki?

Dronabinol mu by'ukuri ni THC yo mu rwego rw'ubuvuzi ikorerwa muri laboratwari aho gukurwa mu gihingwa cya cannabis. Ikintu gikora ni kimwe n'icyo gisanzwe kiboneka muri marijuwana, ariko gikorerwa mu rwego rwo hejuru rw'imiti.

Uyu muti uzasanga ugurishwa ku izina rya Marinol, kandi uza mu buryo bw'ibinini byoroshye bya gélatine ufata unywa. Ibinini birimo umubare wihariye w'ikintu gikora cyashongeshejwe muri amavuta ya sesame, afasha umubiri wawe kuyimira neza.

Igituma dronabinol idasanzwe ni uko ari ikintu kigenzurwa cya Schedule III, bivuze ko ifite imikoreshereze yemewe mu buvuzi ariko igikeneye gukurikiranwa neza. Muganga wawe azagomba kwandika urupapuro rwihariye, kandi uzakenera gukurikiza amabwiriza yihariye iyo uyifata.

Dronabinol ikoreshwa mu iki?

Dronabinol ahanini yandikirwa indwara ebyiri zikomeye aho izindi miti itatanze ubufasha buhagije. Iya mbere ni isuka ikabije no kuruka biterwa na chimiothérapie ya kanseri, cyane cyane iyo imiti isanzwe irwanya isuka itagikora neza.

Uburyo bwa kabiri bwemewe ni ugukoreshwa mu gushishikariza abantu bafite SIDA bafite ibiro bicye cyane kurya. Iyi ndwara, rimwe na rimwe yitwa syndrome yo gutakaza ibiro ya SIDA, ishobora guteza akaga, kandi dronabinol ifasha mu kongera ubushake bwo kurya no kugabanya isesemi ishobora gutuma umuntu adafata amafunguro.

Abaganga bamwe bashobora no kwandika dronabinol ku buryo butemewe kubera izindi ndwara nko kuribwa kw'igihe kirekire, indwara zo gusinzira, cyangwa gutakaza ubushake bwo kurya bukomeye buturutse ku zindi ndwara. Ariko, izi nshingano ntizemewe na FDA, bityo muganga wawe azagereranya neza inyungu n'ibibazo mbere yo kubisaba.

Dronabinol ikora ite?

Dronabinol ikora muguhuza n'utwongera twihariye mu bwonko bwawe no mu mikorere y'imitsi yitwa cannabinoid receptors. Utwo twongera ni igice cy'umubiri wawe gisanzwe gishinzwe kugenzura ibintu nk'ubushake bwo kurya, imitekerereze, n'isesemi.

Iyo ufata dronabinol, ihuzwa n'utwo twongera kandi ishobora gufasha kugabanya kumva isesemi no kongera ubushake bwawe bwo kurya. Ifatwa nk'umuti ukomeye, bivuze ko ushobora kugira akamaro kanini ariko kandi bisaba gupima neza no gukurikiranwa.

Ingaruka zikunze gutangira mu minota 30 kugeza ku masaha 2 nyuma yo kuyifata, kandi zirashobora kumara amasaha 4 kugeza kuri 6. Umubiri wawe ukora umuti unyuze mu mwijima wawe, niyo mpamvu ari ngombwa kwitonda niba ufite ibibazo by'umwijima.

Nkwiriye gufata Dronabinol nte?

Ukwiriye gufata dronabinol nk'uko muganga wawe abitegeka, akenshi inshuro 1 kugeza kuri 3 ku munsi bitewe n'uburwayi bwawe. Ibinini bikwiriye kumirwa byose hamwe n'ikirahure cyuzuye cy'amazi, kandi ntugomba kubifata hamwe n'ibiryo, nubwo abantu bamwe babona ko byoroshye mu gifu cyabo nibabikora.

Kubera isesemi no kuruka, muganga wawe akenshi azatangira kugutangiza urugero ruto kandi ashobora kurwongera buhoro buhoro bitewe n'uko ubyitwaramo. Ni byiza gufata urugero rwawe rwa mbere igihe ushobora kuruhuka amasaha make, kuko ushobora kumva uruka cyangwa ugatuza mugihe umubiri wawe wimenyereza.

Bika imiti yawe ahantu hakonje, humye, hatari hafi y'ubushyuhe n'urumuri. Uyibike mu gikoresho cyayo cy'umwimerere kandi wemeze ko ifunze neza kandi itagerwaho n'abana cyangwa undi wese wayikoresha nabi. Ntukigere usangiza dronabinol yawe n'abandi, kabone n'iyo bafite ibimenyetso bisa.

Mbonereho Igihe Kingana Gite Gikwiye Gufata Dronabinol?

Igihe uzamara ufata dronabinol giterwa n'uburwayi bwawe bwihariye n'uburyo wemera neza imiti. Ku gihombo giterwa na shimi, ushobora kuyikenera gusa mu gihe cyo kuvurwa, mugihe gushishikariza iryo ry'inzara bishobora gusaba kuyikoresha igihe kirekire.

Muganga wawe azajya asuzuma buri gihe niba umuti ugifasha kandi niba inyungu zigikomeza kurenga ingaruka zose. Abantu bamwe barayikenera mu byumweru bike gusa, mugihe abandi bashobora kuyifata mu mezi cyangwa igihe kirekire bayobowe n'abaganga.

Ntuzigere uhagarika gufata dronabinol ako kanya utabanje kuvugana na muganga wawe, cyane cyane niba umaze ibyumweru byinshi uyifata. Umubiri wawe ushobora gukenera igihe cyo kumenyera, kandi guhagarika ako kanya bishobora gutera ibimenyetso byo kuva mu miti nk'umujinya, ibibazo byo gusinzira, cyangwa gusubira kw'ibimenyetso byawe by'umwimerere.

Ni Izihe Ngaruka Ziterwa na Dronabinol?

Kimwe n'indi miti yose, dronabinol ishobora gutera ingaruka, nubwo atari buri wese uzibona. Ingaruka zisanzwe zifitanye isano n'uburyo umuti ugira ingaruka ku mikorere y'imitsi yawe kandi akenshi ziragenda zikemuka uko umubiri wawe umenyera.

Dore ingaruka ushobora kubona, dutangiriye ku zisanzwe cyane:

• Kuribwa umutwe cyangwa kumva ureremba, cyane cyane iyo uhagaze
• Gusinzira cyangwa kumva unaniwe cyane
• Umunwa wumye
• Kumva wishimye cyangwa "uri hejuru"
• Urujijo cyangwa kugorana kwibanda
• Isesemi cyangwa kutamererwa neza mu gifu
• Kuribwa umutwe
• Kugira intege nke cyangwa kunanirwa

Ibi bimenyetso bigaragara kenshi, akenshi bigenda bigabanuka uko umubiri wawe umenyera umuti. Kunywa amazi menshi birashobora gufasha mu kumva umunwa wumye, kandi gufata umuti wawe igihe ushobora kuruhuka bifasha mu kugabanya isereri no gusinzira.

Hariho kandi ibindi bimenyetso bitagaragara cyane ariko bikomeye bisaba ubufasha bwihuse bw'abaganga. Ibi bishobora kubaho ariko bitagaragara kenshi birimo guhinduka gukomeye kw'amarangamutima, kwibeshya, umutima utera cyane, cyangwa ibimenyetso byo kwibasirwa n'umubiri nk'uruhu rurya, kubyimba, cyangwa guhumeka bigoranye.

Niba ubonye ibimenyetso byose bikubabaza cyangwa bikabangamira imirimo yawe ya buri munsi, ntugatinye kuvugana n'umuganga wawe. Akenshi barashobora guhindura urugero rw'umuti cyangwa igihe uwufata kugira ngo bagabanye ibyo bimenyetso mugihe ukibona ibyiza ukeneye.

Ninde utagomba gufata Dronabinol?

Dronabinol ntirinzwe kuri buri wese, kandi hariho ibintu byinshi by'ingenzi ugomba kwirinda uyu muti. Ikintu cy'ingenzi ni uko niba ufite amateka yo gukoresha ibiyobyabwenge, kuko dronabinol ishobora gutuma umuntu abigiraho urugero.

Ntugomba gufata dronabinol niba ufite allergie kuri marijuana, THC, cyangwa amavuta ya sesame (akoreshwa mu gukora ibinini). Abantu bafite indwara zimwe na zimwe z'umutima, cyane cyane abafite umutima wateye vuba cyangwa bafite imirimo y'umutima idahagije, bagomba kwirinda uyu muti.

Indwara zo mumutwe zisaba kwitonda cyane kuri dronabinol. Niba ufite amateka ya schizophrenia, bipolar disorder, cyangwa depression ikomeye, uyu muti ushobora gutuma izo ndwara zirushaho cyangwa zikaba zatera ibibazo.

Kutwita no konsa nabyo ni ibintu by'ingenzi. Dronabinol ishobora gukomeretsa abana bakiri bato kandi ikinjira mu mata y'ibere, bityo ntibisabwa muri ibyo bihe keretse inyungu zirusha cyane ibyago.

Amazina y'ubwoko bwa Dronabinol

Izina rikuru rya marike rya dronabinol ni Marinol, imaze kuboneka kuva mu myaka ya za 1980. Iyi ni yo ifashishwa cyane kandi iza mu mbaraga zitandukanye z'ibinyabutabire byoroshye.

Hariho kandi marike nshya yitwa Syndros, ikaba ari uruvange rwa dronabinol rufata mu kanwa ukoresheje urushinge rwihariye rwo mu kanwa. Uru ruvange rushobora gufasha abantu bagorwa no kumira ibinyabutabire cyangwa bakeneye guhindura imiti neza.

Aya marike yombi arimo ibintu bimwe bikora kandi bikora kimwe, ariko muganga wawe ashobora guhitamo kimwe kuruta ikindi bitewe n'ibyo ukeneye n'uko ubuzima bwawe buhagaze.

Izindi miti isimbura Dronabinol

Niba dronabinol itagukwiriye, hariho izindi nzira nyinshi muganga wawe ashobora gutekereza. Kubijyanye no kuruka no kuribwa, imiti nka ondansetron (Zofran), prochlorperazine (Compazine), cyangwa metoclopramide (Reglan) ni yo ikoreshwa cyane.

Kugira ngo bongere ubushake bwo kurya, muganga wawe ashobora gutanga megestrol acetate (Megace), ari umusemburo w'ubukorano ushobora gufasha kongera ubushake bwo kurya no kongera ibiro. Mirtazapine, umuti uvura umubabaro, nawo rimwe na rimwe ukoreshwa mu buryo butemewe n'amategeko kugira ngo wongere ubushake bwo kurya.

Hariho kandi nabilone (Cesamet), uyu nawo ni undi muti w'ubukorano wa cannabinoid usa na dronabinol ariko ufite ingaruka zitandukanye gato. Abantu bamwe bamererwa neza n'umwe kuruta undi.

Muganga wawe azagufasha gushakisha izi nzira bitewe n'uburwayi bwawe bwihariye, izindi miti urimo gufata, n'uburyo wowe ubwawe witwara ku miti.

Ese Dronabinol iruta Ondansetron?

Niba dronabinol iruta ondansetron biterwa n'uko ubuzima bwawe buhagaze n'icyo urimo kuvura. Ondansetron (Zofran) ni yo miti ikoreshwa mbere na mbere mu kuvura kuribwa guterwa na chimiothérapie kuko ifite akamaro kanini kandi ifite ingaruka nke.

Dronabinol akenshi yagenewe ibibazo aho imiti isanzwe irwanya isesemi nka ondansetron itatanze ubufasha buhagije. Ifite inyungu yiyongereye yo gushobora gutera irari ryo kurya, ibyo ondansetron idakora.

Ariko, dronabinol ifite amahirwe menshi yo kugira ingaruka zirimo isereri, urujijo, n'ibyishimo, ibyo abantu bamwe babona ko bitari byiza. Ondansetron akenshi yihanganirwa neza kandi ntigira ingaruka ku miterere yawe yo mu mutwe.

Muganga wawe akenshi azagerageza ondansetron mbere, kandi niba itagize icyo ikora neza, barashobora kongeraho dronabinol cyangwa kuyihindura. Guhitamo neza biterwa n'ibimenyetso byawe byihariye, izindi ndwara, n'uko witwara kuri buri muti.

Ibibazo bikunze kubazwa kuri Dronabinol

Ese Dronabinol irakwiriye abantu barwaye indwara z'umutima?

Dronabinol isaba kwitonda cyane niba urwaye indwara y'umutima, cyane cyane niba ufite imirimo y'umutima idahagaze cyangwa umaze igihe gito ugize umutima utera. Uyu muti ushobora kongera umuvuduko w'umutima kandi ushobora kugira ingaruka ku gitutu cy'amaraso, ibyo bishobora kuba ikibazo kuri zimwe mu ndwara z'umutima.

Niba ufite indwara y'umutima ihagaze, muganga wawe arashobora gutegeka dronabinol ariko azakugenzura cyane. Bazashaka gutangira n'urugero ruto kandi barebe ibimenyetso byose byerekana ko uyu muti ugira ingaruka ku mirimo y'umutima wawe cyangwa ku gitutu cy'amaraso.

Buri gihe bwire muganga wawe ku bibazo byose by'umutima mbere yo gutangira dronabinol, kandi ubahamagare ako kanya niba wumva ububabare mu gituza, umutima utera cyane, cyangwa guhumeka nabi mu gihe ufata uyu muti.

Nkwiriye gukora iki niba nanyoye dronabinol nyinshi ku buryo butunguranye?

Niba unyoye dronabinol nyinshi ku buryo butunguranye, ikintu cy'ingenzi ni ukuguma utuje kandi ugashaka ubufasha bw'abaganga niba ufite ibimenyetso biteye impungenge. Kwiyongera k'umuti akenshi bitera ingaruka zikomeye z'ibisanzwe aho kuba ibibazo biteye ubuzima bw'akaga.

Ushobora kugira isereri rikomeye, urujijo, guhangayika, umutima utera cyane, cyangwa ibitekerezo bidahuye n'ukuri. Shakisha ahantu heza wo kwicaramo cyangwa kuryamamo, kandi niba bishoboka ugire umuntu ugusanga. Ntukagerageze gutwara imodoka cyangwa gukoresha imashini.

Vugana na muganga wawe, ikigo gishinzwe kurwanya uburozi, cyangwa serivisi zihutirwa niba urimo kugira ibimenyetso bikomeye cyangwa niba utazi neza umutekano wawe. Bashobora gutanga ubuyobozi no kugukurikirana kugeza igihe ingaruka zishirira, ibyo bikunda gufata amasaha menshi.

Nigute nzakora niba nsimbukiye urugero rwa Dronabinol?

Niba usimbukiye urugero rwa dronabinol, rwihutire kurufata uko wibuka, keretse igihe cyo gufata urugero rukurikira kigeze. Muricyo gihe, reka urugero wasimbukiye rugende ukomeze gahunda yawe isanzwe yo gufata imiti.

Ntuzigere ufata urugero ebyiri icyarimwe kugirango wuzuze urugero wasimbukiye, kuko ibyo bishobora kongera ibyago byo kugira ingaruka cyangwa kurenza urugero. Niba ukunda kwibagirwa gufata imiti, tekereza gushyiraho ibyibutso kuri terefone yawe cyangwa ukoreshe umuteguro w'ibinyobwa.

Niba ufata dronabinol kubera isesemi ziterwa na chimiothérapie, gusimbuka urugero bishobora kuvuga ko ugira isesemi nyinshi kuruta uko byari bisanzwe. Vugana n'umuganga wawe niba ufite ibibazo byo gukurikiza gahunda yawe yo gufata imiti cyangwa niba gusimbuka urugero bigira ingaruka zikomeye ku bimenyetso byawe.

Nshobora guhagarika ryari gufata Dronabinol?

Ugomba guhagarika gufata dronabinol gusa ukurikije ubuyobozi bwa muganga wawe, cyane cyane niba umaze iminsi cyangwa amezi menshi uyifata buri gihe. Umubiri wawe ushobora kumenyera umuti, kandi guhagarara ako kanya bishobora gutera ibimenyetso byo kuva mu miti.

Muganga wawe akenshi azagabanya urugero rwawe buhoro buhoro kuruta kubihagarika icyarimwe. Ibi bifasha kugabanya ingaruka zishobora guterwa no kuva mu miti nk'uburakari, ibibazo byo gusinzira, kubura ubushake bwo kurya, cyangwa kugaruka kw'ibimenyetso byawe by'umwimerere.

Igihe cyo guhagarika giterwa n'uburwayi bwawe n'intego z'ubuvuzi. Ku bijyanye n'isuka iterwa na chimiothérapie, ushobora guhagarika igihe uruziga rwawe rw'ubuvuzi rurangira, mugihe gushishikariza irari rishobora gusaba isuzuma rirambye kugirango hamenyekane igihe cyiza cyo guhagarika.

Nshobora gutwara imodoka niba mfata Dronabinol?

Ntugomba gutwara imodoka cyangwa gukoresha imashini mugihe ufata dronabinol, cyane cyane mugihe utangiye imiti cyangwa mugihe urugero rwawe ruhinduka. Imiti irashobora gutera isereri, gusinzira, urujijo, n'igihe gito cyo gusubiza ibintu bituma gutwara imodoka bigira akaga.

N'ubwo wumva umeze neza, dronabinol irashobora kwangiza imitekerereze yawe n'ubuhuza mu buryo ushobora kutabona. Ibyo bishobora kumara amasaha menshi nyuma yo gufata urugero rwawe, bityo teganiriza neza kandi utegure uburyo bwo gutwara abantu.

Abantu bamwe bashobora gutwara neza imodoka bamaze igihe bafata urugero ruhamye kandi bazi uko imiti ibagira, ariko icyemezo kigomba gufatwa buri gihe hamwe n'umuganga wawe kandi gishingiye ku buryo wabyakiriye ku miti.