Lucinactant ni iki: Ibikoresho, Urutonde rw'imiti, Ingaruka zayo n'ibindi

Lucinactant ni umuti w'imiterere ya surfactant y'ibihaha utangwa mu buryo butaziguye mu muyoboro w'umwuka w'abana bavutse imburagihe bafite ibibazo byo guhumeka. Uyu muti wihariye ufasha ibihaha bito gukora neza mugihe ugabanya imbaraga ziri hejuru mu mufuka w'umwuka, bigatuma abana bakivuka bahumeka neza bonyine.

Iyo abana bavutse kare cyane, ibihaha byabo ntibiba byabonye umwanya uhagije wo gukora ikintu gisanzwe cyitwa surfactant. Tekereza surfactant nk'isabune ibuza imifuka mito y'umwuka mu bihaha byawe gusenyuka. Bitabayeho, guhumeka biragora cyane kandi bigateza akaga kuri aba bana boroheje.

Lucinactant ikoreshwa kubera iki?

Lucinactant ivura indwara yo guhumeka (RDS) mu bana bavutse imburagihe. RDS ibaho iyo abana bavutse mbere yuko ibihaha byabo bishobora gukora surfactant isanzwe, akenshi mbere y'ibyumweru 37 byo gutwita.

Iyi ndwara ituma guhumeka bikora cyane ku bana bakivuka kuko imifuka mito y'umwuka mu bihaha byabo ikomeza gusenyuka buri gihe bahumeka. Hatabonetse ubuvuzi, abana bafite RDS bahura n'ingorane zo kubona umwuka uhagije mu maraso yabo, bishobora guteza akaga gakomeye.

Abaganga bakoresha lucinactant mu bihe bibiri by'ingenzi. Icya mbere, barayitanga kugirango birinde RDS mu bana bavutse imburagihe cyane bafite ibyago byinshi. Icya kabiri, barayikoresha kuvura abana bamaze kugaragaza ibimenyetso by'ibibazo byo guhumeka nyuma yo kuvuka.

Lucinactant ikora ite?

Lucinactant ikora isimbura surfactant isanzwe yaburiwe mu bihaha by'abana bavutse imburagihe. Uyu muti urimo verisiyo ya sintetike ya poroteyine n'ibinure ibihaha bifite ubuzima bwiza bikora mu buryo busanzwe.

Iyo abaganga bashyize lucinactant mu buryo butaziguye mu muyoboro w'umwuka w'umwana, ikwirakwira mu bihaha byose kandi ikora ibice byimbere byimifuka y'umwuka. Iyi coating irinda imifuka y'umwuka gushyira hamwe no gusenyuka iyo umwana ahumeka.

Umuti ukora vuba, akenshi ugatuma guhumeka kurushaho mu minota mike kugeza ku masaha nyuma yo kuwutanga. Bitandukanye na bimwe mu bindi bisanzwe, lucinactant irimo poroteyine ishobora gutanga inyungu zinyongera ku mikorere y'ibihaha no gukira.

Lucinactant Igomba Gutangwa Gute?

Lucinactant igomba gutangwa gusa n'abaganga bafite imyitozo idasanzwe muri serivisi y'abarwayi barembye (NICU) mu bitaro. Uyu muti ujya mu muyoboro w'umwuka w'umwana unyuze mu tuyunguruzo tw'umwuka, ntabwo unyuze mu kanwa cyangwa mu miyoboro y'amaraso.

Mbere yo gutanga lucinactant, abaganga bashyushya uyu muti ku bushyuhe bw'umubiri kandi bakawutegurira ahantu hasukuye. Umwana akenshi ahabwa uyu muti akoresheje imashini ifasha guhumeka cyangwa imashini ifasha guhumeka ifasha gufasha guhumeka kwabo.

Ubu buryo burimo gupima neza urugero rwawo rukurikije uburemere bw'umwana no kuwutanga buhoro buhoro unyuze mu tuyunguruzo tw'umwuka. Abaganga bakurikirana umuvuduko w'umutima w'umwana, urugero rwa ogisijeni, n'uburyo bwo guhumeka neza mugihe cyo kuvura no nyuma yaho.

Lucinactant Igomba Gukoreshwa Igihe Kingana Gite?

Abana benshi bahabwa lucinactant nk'urugero rumwe, nubwo bamwe bashobora gukenera izindi doze mu minsi mike ya mbere y'ubuzima. Icyemezo gishingiye ku buryo umwana yitwara neza niba guhumeka kwe kurushaho.

Abaganga akenshi batanga doze zigera kuri enye zose, zikaba zaratanzwe nibura amasaha atandatu, niba umwana akomeje kugira ingorane zo guhumeka. Doze imwe imwe ibarwa neza hakurikijwe uburemere bw'umwana n'ubuzima bwe bwo kwa muganga.

Ingaruka za lucinactant zirashobora kumara iminsi cyangwa ibyumweru igihe ibihaha by'umwana ubwabyo bigenda bikura buhoro buhoro kandi bigatangira gukora surfactant karemano. Abana benshi bagaragaza impinduka mu masaha make nyuma yo guhabwa doze yabo ya mbere.

Ni Iyihe Miterere Igenda Igaragara Itera Lucinactant?

Ingaruka zisanzwe zigaragara mugihe cyo gutanga lucinactant zirimo impinduka z'agateganyo kumuvuduko w'umutima n'umuvuduko w'amaraso. Ibi bikunda kubaho mugihe cyo kuvura ubwacyo kandi bikunze gukemuka vuba mugihe umuti utanzwe neza.

Abana bamwe bashobora guhura n'ibihe bigufi aho urwego rw'umwuka wa oxygen ruhindagurika cyangwa uburyo bwabo bwo guhumeka buhinduka mugihe cyo kuvurwa. Abaganga b'ubuzima bategereza ibi bikorwa kandi bagenzura abana buri gihe kugirango bamenye umutekano.

Hano hari ingaruka zikunze kugaragara abaganga bareba mugihe cyo kuvura:

• Kugabanya cyangwa kwihutisha umuvuduko w'umutima by'agateganyo
• Kugabanuka guto k'umuvuduko w'amaraso
• Impinduka zigufi mu rwego rwa oxygen
• Impinduka z'agateganyo muburyo bwo guhumeka
• Impinduka nto mumiterere y'umwuka wa karuboni diokiside mumaraso

Izi ngaruka muri rusange ziroroshye kandi zishobora gucungwa neza n'ubuyobozi bw'ubuvuzi bukwiye. Inyungu zo guhumeka neza zikunze kurenga izi mpungenge z'agateganyo.

Ibikomere bikomeye biragoye ariko bishobora kwirimo pneumothorax (igihaha cyaguye) cyangwa kuva amaraso mumahu. Ariko, ibi bibazo bikomeye bikunze gufitanye isano no kuvuka imburagihe n'ingorane zo guhumeka aho kuba umuti ubwawo.

Ninde utagomba guhabwa Lucinactant?

Abana bake cyane ntibashobora guhabwa lucinactant, ariko abaganga basuzuma buri kibazo neza. Uyu muti wagenewe abana bavukiye imburagihe bafite ibibazo byo guhumeka, bityo ntibikwiye kubana bavukiye igihe cyangwa abafite izindi ngorane z'umwijima.

Abana bafite ubumuga bukomeye bwo kuvuka bugira ingaruka kumiyoboro yabo y'umwuka cyangwa ibihaha ntibashobora kuba abakandida bo kuvurwa na lucinactant. Byongeye kandi, abana bafite kuva amaraso mumahu cyangwa abatarashobora gukoresha uburyo bwo gutanga bashobora gukenera gutegereza.

Abaganga banatekereza ku miterere y'umwana muri rusange, harimo imikorere y'umutima n'ubushobozi bwo kuvura amaraso, mbere yo gufata icyemezo cyo kuvura. Rimwe na rimwe igihe cyo kuvura kigira akamaro kurusha ibituma bitabaho.

Amazina ya Lucinactant

Lucinactant icururizwa ku izina rya Surfaxin muri Leta Zunze Ubumwe z'Amerika. Iyi ni yo miterere yonyine y'uyu muti wihariye wa surfactant ukorwa.

Abaganga n'ababyeyi bashobora kumva bivugwa ku izina ryayo rusange (lucinactant) cyangwa izina ry'ubucuruzi (Surfaxin) mu buryo buvunguranye. Aya mazina yombi yerekeza ku muti umwe ufite ibikoresho bimwe n'ingaruka zimwe.

Uburyo bwo gusimbuza Lucinactant

Hariho indi miti ya surfactant itandukanye iboneka yo kuvura indwara yo guhumeka mu bana bavukiye igihe kitaragera. Ibi birimo surfactants karemano zikomoka mu bihaha by'inyamaswa n'izindi miterere ya sintetike.

Surfactants karemano nka beractant (Survanta) na poractant alfa (Curosurf) zikomoka mu bihaha by'inka cyangwa ingurube kandi zimaze imyaka myinshi zikoreshwa neza. Iyi miti ikora kimwe na lucinactant ariko ifite ibigize bitandukanye gato.

Uundi muti wa sintetike ni colfosceril palmitate (Exosurf), nubwo ubu ukoreshwa gake. Guhitamo hagati ya surfactants zitandukanye akenshi biterwa n'ibyo ibitaro bikunda, uko ziboneka, n'ibintu by'umuntu ku giti cye.

Ese Lucinactant iruta izindi surfactants?

Lucinactant itanga inyungu zidasanzwe ugereranije n'indi miti ya surfactant, cyane cyane imiterere yayo ya sintetike n'ibikubiye muri poroteyine. Kuba ari sintetike bisobanura ko idashobora gutera indwara zikomoka ku nyamaswa, ibyo bishobora kuba impungenge kuri surfactants karemano.

Umuti urimo igice cya poroteyine gishobora gutanga izindi nyungu zo gukiza ibihaha no gukora neza urenze gusa gukumira imifuka y'umwuka. Ubushakashatsi bumwe buvuga ko ibi bishobora gutuma haboneka ibisubizo byiza mu gihe kirekire.

Ariko, ibinyabutabuzi byose byemewe bifite akamaro kanini mu kuvura indwara yo guhumeka bigoye. Guhitamo hagati yabyo akenshi biterwa n'ibintu nk'amabwiriza y'ibitaro, ibitekerezo by'ikiguzi, n'uburambe bw'abaganga aho kuba itandukaniro rikomeye mu mikorere.

Ibikunze Kubazwa Kuri Lucinactant

Ese Lucinactant iratekanye ku bana bavutse imburagihe?

Yego, lucinactant ifatwa nk'itekaniye cyane iyo itanzwe n'abavuzi b'ubuzima bafite imyitozo mu bitaro bikwiye. Uyu muti wanyuze mu igeragezwa ryimbitse cyane cyane ku bana bavutse imburagihe kandi wemejwe n'inzego zigenzura.

Uburyo bwo gutekana bwemejwe neza, hamwe n'ingaruka nyinshi ziba iz'agateganyo kandi zishobora gucungwa. Inyungu zo guhumeka neza no kugabanya ibyago by'ingorane zikomeye zituruka ku ndwara yo guhumeka bigoye akenshi biruta ibyago byose bishoboka.

Nigira iki niba umwana wanjye yakoresheje Lucinactant nyinshi cyane?

Ibihe byo kurenza urugero ni bike cyane kuko lucinactant itangwa gusa n'abantu b'inzobere mu by'ubuvuzi bafite imyitozo bagenzura neza imiti. Abavuzi b'ubuzima bakoresha ingero zizewe zishingiye ku gipimo cy'umwana wawe kandi bagakurikirana neza uburyo bwo gutanga imiti.

Niba imiti myinshi yatanzwe mu buryo butunganye, abakozi b'ubuvuzi bahita bongera gukurikirana kandi bagatanga ubufasha nk'uko bikwiye. Itsinda ry'ibitaro rifite ibikoresho byo guhangana n'ingorane zose zishobora kuvuka zituruka ku makosa y'imiti.

Bikunda kugenda bite niba umwana wanjye atabonye urugero rwatanzwe?

Bitandukanye n'imiti ifatirwa mu rugo, gutanga lucinactant byose bicungwa n'ikipe y'ubuvuzi y'umwana wawe mu bitaro. Bakomeza gusuzuma niba urundi rugero rukenewe hashingiwe ku buryo umwana wawe ahumeka n'ubuzima bwe muri rusange.

Niba urugero rutinze kubera impamvu z'ubuvuzi, abaganga bazagena igihe cyiza cyo gutanga hashingiwe ku byo umwana wawe akeneye ubu. Gahunda yo kuvura irashobora guhindurwa kugirango umwana wawe ahabwe ubuvuzi bwiza.

Umwana wanjye ashobora kureka kwakira Lucinactant ryari?

Abana benshi bakira lucinactant mu minsi yabo ya mbere y'ubuzima gusa, kandi benshi bakenera doze imwe cyangwa ebyiri gusa. Ubuvuzi buhagarara igihe umwana wawe ahumeka neza kandi amabuye ye atangira gukora surfactant isanzwe ihagije.

Itsinda ry'abaganga rikora igenzura rihoraho ku iterambere ry'umwana wawe kandi rifata ibyemezo ku bijyanye na doze zindi zishingiye ku buryo ahumeka, uko akeneye umwuka wa oxygen, n'iterambere rusange ry'ubuvuzi. Igihe amabuye y'umwana wawe akura, azagenda akena ubufasha buke bwo guhumeka.

Ese Lucinactant izagira ingaruka ku mikurire y'umwana wanjye mu gihe kirekire?

Ubushakashatsi buriho bwerekana ko ubuvuzi bwa lucinactant ntibugira ingaruka mbi ku mikurire y'igihe kirekire ku bana bavukiye igihe kitaragera. Mubyukuri, mu kunoza guhumeka no gutanga oxygen mu minsi ya mbere y'ingenzi, umuti ushobora gufasha kwirinda ibibazo bishobora kugira ingaruka ku mikurire.

Inyigo zikurikira abana bakiriye ubuvuzi bwa surfactant zerekana ibisubizo bisa by'iterambere nk'ibiteganijwe ku rugero rw'igihe batarageza igihe cyo kuvuka. Umuti uvura ikibazo cyo guhumeka ako kanya utagize ingaruka zirambye ku mikurire cyangwa iterambere.