Procainamide (Uburyo bwo mu mitsi): Ibyo ikoreshwa, urugero rwo gufata, ingaruka ziterwa n'ibindi

Procainamide ni umuti wandikirwa na muganga utangwa unyuze mu muyoboro w'imitsi (intravenous) kugira ngo uvure ibibazo bikomeye by'umutima. Uyu muti ubarizwa mu cyiciro cy'imiti yitwa antiarrhythmics, ikora igihe ishyira mu gaciro ibimenyetso by'amashanyarazi mu mutima wawe kugira ngo isubize umutima mu buryo busanzwe, buhoro.

Uyu muti akenshi ukoreshwa mu bitaro igihe umutima wawe ukeneye ubufasha bwihuse kugira ngo usubire mu murimo usanzwe. Itsinda ry'abaganga bazagukurikiranira hafi igihe uri guhabwa uyu muti kugira ngo barebe ko ukora neza kandi neza.

Procainamide ikoreshwa mu kuvura iki?

Procainamide IV ikoreshwa cyane cyane mu kuvura indwara ziteye akaga z'umutima zikeneye ubufasha bwihuse. Muganga wawe azahitamo uyu muti igihe umutima wawe utera cyane, mu buryo butari bumwe, cyangwa mu buryo bushobora gushyira ubuzima mu kaga.

Indwara zisanzwe ivura zirimo ventricular tachycardia (igihe ibice byo hepfo by'umutima wawe bitera cyane) na atrial fibrillation (igihe ibice byo hejuru bitera mu buryo butari bumwe). Ifasha kandi mu bindi bibazo bikomeye by'umutima nka ventricular fibrillation, aho imikorere y'amashanyarazi y'umutima wawe ihinduka uruvunganzoka.

Rimwe na rimwe abaganga bakoresha procainamide IV mu gihe cyo kubaga umutima cyangwa kubaga kugira ngo birinde ibibazo by'umutima. Bifasha kandi igihe indi miti y'umutima itakoze cyangwa igihe ukeneye ibisubizo byihuse kuruta imiti yo kunywa.

Procainamide ikora ite?

Procainamide ikora igihe ibuza inzira zihariye z'amashanyarazi mu mikaya y'umutima wawe yitwa sodium channels. Tekereza izi nzira nk'inzugi nto zigenzura uburyo ibimenyetso by'amashanyarazi bigenda mu gice cy'umutima wawe.

Iyo izi nzira zikora cyane, umutima wawe ushobora kugira imirimo iteye akaga. Procainamide mu by'ukuri ituma ibi bimenyetso by'amashanyarazi bigenda gake, biha umutima wawe umwanya wo gusubiramo no kongera kubona imirimo yawo isanzwe, ihoraho.

Uyu muti ufatwa nk'umuti ukomeye wo kuvura umutima utagira umurongo. Ufite imbaraga zihagije zo guhangana n'ibibazo bikomeye by'umutima ariko bisaba gukurikiranwa neza kuko bishobora kugira ingaruka ku mikorere y'amashanyarazi y'umutima wawe mu buryo bugoye.

Nkwiriye Gufata Procainamide Nte?

Procainamide IV ihabwa buri gihe n'abashinzwe ubuzima mu bitaro cyangwa ahantu hakorerwa ibizamini by'ubuzima. Ntabwo bizagusaba gufata uyu muti wenyine - itsinda ryawe ry'abaganga rizita ku bintu byose.

Uyu muti uca mu maraso yawe mu buryo butaziguye binyuze mu muyoboro wa IV, akenshi ushyirwa mu kuboko kwawe cyangwa ukuboko. Umuforomo wawe azatangira gutera umuti buhoro buhoro kandi buhoro buhoro agahindura umuvuduko bitewe n'uko umutima wawe witwara.

Ntabwo bisaba kurya cyangwa kunywa ikintu icyo aricyo cyose mbere yo guhabwa uyu muti. Ariko, itsinda ryawe ry'abaganga rishobora kugusaba kwirinda ibiryo cyangwa ibinyobwa runaka bitewe n'ubuzima bwawe muri rusange n'indi miti urimo gufata.

Mugihe cyo kuvurwa, uzahuzwa n'ibikoresho byo gukurikirana umutima bikurikirana umurongo wawe buri gihe. Ibi bifasha itsinda ryawe ry'abaganga kureba uko umuti ukora neza no gukora impinduka zose zikenewe kugirango ugumane umutekano.

Nkwiriye Gufata Procainamide Igihe Kingana Gite?

Igihe cyo kuvurwa na procainamide IV gitandukanye cyane bitewe n'uburwayi bw'umutima wawe bwihariye n'uko witwara vuba ku muti. Abantu bamwe barawukeneye amasaha make gusa, mu gihe abandi bashobora gusaba iminsi myinshi yo kuvurwa.

Muganga wawe azahagarika procainamide IV igihe umurongo w'umutima wawe umaze guhagarara kandi ukaguma uko byari bisanzwe igihe giteganyijwe. Bazatekereza kandi kukwimurira ku miti yo mu kanwa y'umutima ushobora gufata mu rugo niba ukeneye kuvurwa igihe kirekire.

Umutuzo ku gihe biterwa n'ibintu byinshi: icyateye ikibazo cy'umurongo wawe, uko byari bikomeye, niba ufite indwara z'umutima ziriho. Itsinda ryawe ry'abaganga rizasobanura gahunda yabo yo kuvura kandi bakugumisha ku makuru yerekeye igihe giteganyijwe.

Ni Ibihe Bikorwa Bibi bya Procainamide?

Kimwe n'imiti yose, procainamide IV ishobora gutera ibikorwa bibi, nubwo abantu benshi bayihanganira neza iyo bakurikiranwa neza. Itsinda ry'ubuvuzi ryawe rirakurikiranira hafi ibi bikorwa kandi rishobora guhindura uburyo uvurwa niba bibaye ngombwa.

Ibikorwa bibi bisanzwe ushobora guhura nabyo birimo kumva uribwa umutwe, kuruka, cyangwa kugira umutwe. Abantu bamwe babona ko umuvuduko w'amaraso yabo ugabanuka, ibyo bishobora gutuma bumva bacitse intege cyangwa bafite intege nke. Ibi bikorwa mubisanzwe birashoboka kandi akenshi birakosoka uko umubiri wawe wimenyereza.

Dore ibikorwa bibi bisanzwe abaganga bakurikiranira hafi:

• Kuribwa umutwe cyangwa kumva ucika intege
• Kuruka cyangwa kurwara inda
• Umutwe
• Umuvuduko w'amaraso muke
• Kumva unaniwe cyangwa ufite intege nke
• Kugira uruhu rutukura cyangwa gushyuha mu maso yawe

Ibi bikorwa mubisanzwe biroroshye kandi by'agateganyo, ariko itsinda ryawe ry'ubuvuzi rizafasha gukemura ibibazo byose wahura nabyo.

Ibikorwa bibi bikomeye ntibisanzwe ariko bisaba kwitabwaho ako kanya. Itsinda ryawe ry'ubuvuzi ryatojwe kumenya no gusubiza vuba, bityo uri mu maboko meza.

Ibikorwa bibi bikomeye abakozi b'ubuvuzi bakurikiranira hafi birimo:

• Ibibazo bishya cyangwa bikomeye by'umuvuduko w'umutima
• Umuvuduko w'amaraso ugabanuka cyane
• Uko umubiri wifata ku miti n'uruhu cyangwa ingorane zo guhumeka
• Ibimenyetso bya syndrome nk'iya lupus (kuribwa mu ngingo, umuriro, uruhu rutukura)
• Indwara z'amaraso zigira ingaruka ku ngirangingo zirwanya indwara zawe
• Ibibazo by'umwijima (uruhu cyangwa amaso y'umuhondo)

Wibuke, urakurikiranwa buri gihe mugihe ukoresha uyu muti, bityo impinduka zose ziteye inkeke zizafatwa kandi zivurwe ako kanya.

Ninde Utagomba Gufata Procainamide?

Procainamide ntabwo ifite umutekano kuri buri wese, kandi itsinda ryawe ry'ubuvuzi rizasuzuma neza amateka yawe y'ubuzima mbere yo gutangira ubuvuzi. Bazatekereza ku miti urimo gufata ubu, indwara z'ubuvuzi, n'uburyo wigeze kwifata ku miti isa.

Ntabwo wagombye guhabwa procainamide IV niba waragize allergie ikomeye kuri yo cyangwa imiti ifitanye isano nayo nka procaine cyangwa lidocaine. Abantu bafite indwara zimwe na zimwe z'umutima, nk'umutima wuzuye, ntibashobora kuba bakwiriye ubu buvuzi.

Muganga wawe azitonda cyane niba ufite kimwe muri ibi bikurikira:

• Ibibazo by'impyiko cyangwa indwara y'impyiko
• Indwara y'umwijima cyangwa imikorere mibi y'umwijima
• Lupus cyangwa izindi ndwara ziterwa n'umubiri w'umuntu
• Umubyimba muke cyangwa kunanirwa k'umutima
• Ubwoko bumwe na bumwe bwo guhagarara k'umutima
• Myasthenia gravis (indwara itera intege nke z'imitsi)

Gusama no konsa bisaba kwitonderwa byihariye, nubwo procainamide ishobora gukoreshwa rimwe na rimwe iyo inyungu ziruta ibyago. Itsinda ryawe ry'ubuzima rizaganira nawe ku buryo bwose.

Amazina ya Procainamide

Procainamide IV iboneka mu mazina menshi y'ubwoko, nubwo kandi isanzwe iboneka nk'umuti rusange. Izina rizwi cyane ni Pronestyl, nubwo bishobora gutandukana bitewe n'igihugu n'umukora.

Andi mazina y'ubwoko arimo Procan SR na Procanbid, nubwo ibi bisanzwe ari imiti yo kunywa. Ibitaro byawe bizakoresha uburyo ubwo aribwo bwose bwa IV buboneka kandi bukwiye kuvura indwara yawe.

Ubwoko rusange bukora kimwe neza nk'ubwoko bw'amazina kandi bukurikiza amategeko y'umutekano n'ubushobozi. Itsinda ryawe ry'ubuzima rizagena uburyo bwiza bushingiye ku kuboneka n'ibyo ukeneye byihariye.

Uburyo bwo gusimbuza Procainamide

Imiti myinshi ya IV ishobora kuvura ibibazo bikomeye by'umutima niba procainamide itagukwiriye. Muganga wawe azahitamo uburyo bwiza bushingiye ku bwoko bw'umutima wawe n'ubuzima bwawe muri rusange.

Uburyo busanzwe bwo gusimbuza burimo amiodarone, akenshi ikoreshwa mu bibazo bisa nk'ibyo ariko ikora mu buryo butandukanye. Lidocaine ni ubundi buryo, cyane cyane kubwoko bumwe na bumwe bwa ventricular arrhythmias.

Izindi nzira zishobora gukoreshwa n'abaganga bawe zirimo:

• Amiodarone (Cordarone) - ikoreshwa cyane mu kurwanya indwara z'umutima zituma umutima utera nabi
• Lidocaine - cyane cyane mu bibazo by'umutima utera nabi
• Sotalol - mu kurwanya indwara z'umutima zituma umutima utera nabi haba mu gice cy'umutima cyangwa mu gice cy'umutima gitera nabi
• Flecainide - mu bwoko bumwe na bumwe bw'indwara z'umutima zituma umutima utera nabi
• Propafenone - ikindi gihindura imikorere y'umubiri

Itsinda ry'abaganga bazagusobanurira impamvu bahisemo umuti runaka n'uko ugereranywa n'izindi nzira zishobora gukoreshwa mu gihe cy'ikibazo cyawe.

Ese Procainamide iruta Amiodarone?

Procainamide na amiodarone ni imiti ikora neza mu kurwanya indwara z'umutima zituma umutima utera nabi, ariko bakora mu buryo butandukanye kandi bikwiriye mu bihe bitandukanye. Nta na umwe uruta undi - guhitamo biterwa n'ikibazo cy'umutima wawe n'ubuzima bwawe muri rusange.

Procainamide ikora vuba kandi akenshi ikoreshwa mu bihe bikomeye aho gukontorora umutima byihutirwa. Ikora neza cyane mu bwoko bumwe na bumwe bw'indwara z'umutima zituma umutima utera nabi kandi ishobora guhitwamo igihe gikorwa cyihuse ari ngombwa.

Amiodarone, ku rundi ruhande, akenshi ikora neza mu gihe kirekire cyo gukontorora umutima kandi ikora neza haba mu gice cy'umutima cyangwa mu gice cy'umutima gitera nabi. Ariko, ifite igihe kirekire cyo gutangira gukora kandi ifite ibyago byinshi byo kugira ingaruka mbi mu gihe kirekire.

Umuvuzi w'indwara z'umutima azatekereza ibintu nk'ubwoko bw'indwara yawe y'umutima, uko ukeneye kuvurwa vuba, izindi ndwara ufite, n'ingaruka zishobora guterwa n'imiti iyo ariyo yose mu guhitamo hagati y'iyi miti.

Ibibazo bikunze kubazwa kuri Procainamide

Q1. Ese Procainamide irakwiriye ku bantu barwaye indwara z'impyiko?

Procainamide irashobora gukoreshwa ku bantu barwaye indwara z'impyiko, ariko bisaba guhindura urugero rw'umuti witonze no gukurikiranwa cyane. Impyiko zawe zigufasha gukuramo uyu muti mu mubiri wawe, bityo kugabanuka kw'imikorere y'impyiko bivuze ko umuti ushobora kumara igihe kirekire mu mubiri wawe.

Itsinda ryawe ry’abaganga rizagena urugero rwa imiti rishingiye ku bizami by’imikorere y’impyiko zawe kandi bazakugenzura kenshi kugira ngo barebe ingaruka ziterwa n’iyo miti. Bashobora kandi gukoresha igihe gito cyo kuyongera mu maraso cyangwa urugero ruto kugira ngo bagufashe kuguma mu mutekano mu gihe bagikora ibijyanye n’umuvuduko w’umutima wawe neza.

Q2. Nkwiriye gukora iki niba ngize ingaruka ziterwa na Procainamide?

Kubera ko procainamide IV itangwa mu bitaro, itsinda ryawe ry’ubuzima rizakugenzura buri gihe kugira ngo barebe ingaruka ziterwa n’iyo miti. Niba ubonye ibimenyetso bidasanzwe cyangwa kutumva neza, menyesha umuganga wawe cyangwa umuforomo ako kanya.

Ntugire impungenge ku ngaruka nto nk'isuka ryoroheje cyangwa isereri - ibi ni ibisanzwe kandi itsinda ryawe ry’ubuzima rirabiteganya. Ariko, jya uvuga ibijyanye n'ikimenyetso icyo ari cyo cyose kikureba, kuko umutekano wawe n'imibereho myiza ni byo biza imbere.

Q3. Procainamide imara igihe kingana iki mu mubiri wanjye?

Procainamide isanzwe imara mu mubiri wawe hafi amasaha 6-8 nyuma yo guhagarika IV, nubwo ibi bishobora gutandukana bitewe n’imikorere y’impyiko zawe n’ubuzima muri rusange. Umubiri wawe usenya imiti vuba ugereranije n’indi miti imwe yo mu mutima.

N'iyo imiti ivuyeho, ingaruka zayo ku muvuduko w'umutima wawe zishobora gukomeza igihe gito. Itsinda ryawe ry’ubuzima rizakomeza kugenzura umutima wawe nyuma yo guhagarika kuyongera mu maraso kugira ngo barebe ko umuvuduko wawe ukomeza kuba mwiza.

Q4. Nshobora gutaha mu gihe nkoresha Procainamide IV?

Oya, procainamide IV itangwa gusa mu bitaro cyangwa ahantu hakorerwa ibizamini aho ushobora kugenzurwa buri gihe. Iyi miti isaba kugenzurwa hafi kuko ishobora kugira ingaruka ku muvuduko w'umutima wawe n'umuvuduko w'amaraso mu buryo busaba ubufasha bwihuse bw'abaganga.

Iyo umuvuduko w'umutima wawe uhagaze neza kandi muganga wawe yumva ko byemewe, ushobora guhindurirwa imiti yo kunywa ushobora gufata uri mu rugo. Itsinda ryawe ry’ubuzima rizagufasha kwitegura kuva mu bitaro kandi ufite gahunda isobanutse yo kwitabwaho.

Q5. Nzaba nkeneye ibizamini by'amaraso mu gihe nkoresha Procainamide?

Yego, ikipe yawe y'abaganga ishobora gutegeka ibizamini by'amaraso kugira ngo bagenzure uko umubiri wawe witwara kuri procainamide. Ibi bizamini bifasha kureba imikorere y'impyiko zawe, umubare w'uturemangingo tw'amaraso, n'urugero rw'imiti kugira ngo barebe ko umuti ukora neza.

Uburyo ibizamini by'amaraso bikorwa biterwa n'igihe umaze ufata umuti n'ibintu byihariye bigushyira mu kaga. Ikipe yawe y'ubuvuzi izasobanura ibizamini bikenewe n'icyo ibisubizo bisobanuye ku buryo uvurwa.