Icyo Propylthiouracil ari cyo: Ibyo ikoreshwa, urugero rwa dose, ingaruka ziterwa n'ibindi

Propylthiouracil ni umuti ufasha kugabanya umuvuduko w'umusemburo wa thyroïde ukora cyane. Thyroïde yawe ikora imisemburo igenzura imirimo myinshi mu mubiri wawe, harimo umuvuduko w'umutima wawe, imikorere y'umubiri, n'imbaraga. Iyo iyi ngingo ikora cyane, propylthiouracil irinjira kugira ngo ifashe kugarura uburinganire igabanya umubare w'imisemburo ya thyroïde umubiri wawe ukora.

Propylthiouracil ni iki?

Propylthiouracil, akenshi yitwa PTU, ni umuti urwanya thyroïde ubarizwa mu itsinda ry'imiti yitwa thionamides. Ikora ibi ikingira thyroïde yawe gukora imisemburo ya thyroïde nyinshi cyane, bishobora gutera ibimenyetso bitari byiza kandi bishobora kuba bikomeye iyo urwego rugeze hejuru cyane.

Uyu muti umaze imyaka myinshi ufasha abantu gucunga indwara ya thyroïde ikora cyane. Muganga wawe ashobora kuwugusabira iyo thyroïde yawe ikora imisemburo y'ikirenga, igatera ibimenyetso nk'umutima wihuta, kugabanya ibiro, guhangayika, cyangwa kubira ibyuya. PTU ifasha kugarura uru rwego rw'imisemburo mu rwego ruzima.

Propylthiouracil ikoreshwa mu iki?

Propylthiouracil ivura hyperthyroïdie, indwara aho thyroïde yawe ikora imisemburo ya thyroïde nyinshi cyane. Uburyo busanzwe bwa hyperthyroïdie ni indwara ya Graves, indwara y'ubwirinzi aho sisitemu yawe y'ubwirinzi yibeshya igatera thyroïde yawe gukora cyane.

Muganga wawe ashobora kandi kugusabira PTU kugira ngo agutegure kubagwa thyroïde cyangwa kuvurwa na iodine ya radiyo. Muri ibi bihe, uyu muti ufasha kugarura urwego rw'imisemburo ya thyroïde mbere y'igihe, bigatuma ubu buryo burushaho kuba bwiza kandi bwizewe.

Mugihe cyo gutwita, PTU iba ingenzi cyane kuko akenshi ni umuti urwanya thyroïde ukunda gukoreshwa ku bagore batwite. Indi miti isa n'iyi ishobora kwambuka placenta byoroshye kandi igashobora kugira ingaruka ku mwana ukura, bigatuma PTU iba uburyo bwiza muri iki gihe cyihariye.

Propylthiouracil ikora ite?

PTU ikora igihe ibangamiye ubushobozi bwa thyroïde yawe bwo gukoresha iyode kugirango ikore imisemburo ya thyroïde. Tekereza iyode nk'igikoresho cy'ingenzi thyroïde yawe ikeneye kugirango ikore iyi misemburo. PTU mu by'ukuri ibuza zimwe mu nzira thyroïde yawe ikoresha kugirango ihindure iyode mu musemburo wa thyroïde ukora.

Uyu muti ufatwa nk'ukomeye ku rugero ruciriritse kandi akenshi utangira gukora nyuma y'ibyumweru bike ukoreshwa buri gihe. Bitandukanye na imwe mu miti ikora ako kanya, PTU ikeneye igihe kugirango yiyongere mu mubiri wawe kandi buhoro buhoro igabanye imisemburo ya thyroïde yarenze urugero isanzwe izenguruka mu mubiri wawe.

Uyu muti kandi ufite ingaruka ya kabiri hanze ya glande ya thyroïde. Irashobora kubuza ihinduka ry'ubwoko bumwe bw'imisemburo ya thyroïde (T4) mu buryo bwayo bukora cyane (T3) mu bindi bice by'umubiri wawe, bitanga ubufasha bwiyongera mu gucunga ibimenyetso byawe.

Nkwiriye gufata Propylthiouracil nte?

Fata PTU nkuko muganga wawe abitegeka, akenshi kabiri cyangwa gatatu ku munsi hamwe n'ibiryo cyangwa amata. Kuyifata hamwe n'ibiryo bifasha kugabanya kuribwa mu gifu, ibyo abantu bamwe bahura nabyo iyo bafata umuti ku gifu cyuzuye.

Urashobora gufata PTU hamwe n'amazi, amata, cyangwa umutobe. Abantu benshi basanga kuyifata mu gihe kimwe buri munsi bibafasha kwibuka imiti yabo kandi bigatuma urugero rw'umuti ruguma ruhamye mu mubiri wabo. Gerageza gutandukanya imiti yawe mu buryo bungana umunsi wose niba ufata imiti myinshi.

Mbere yo gufata umuti wawe, ntugomba kurya ibiryo byihariye, ariko kugira ikintu mu gifu cyawe muri rusange birafasha. Ifunguro rito cyangwa ibiryo byoroheje bikora neza. Irinde gufata PTU ku gifu cyuzuye, cyane cyane niba ukunda kuribwa cyangwa kumva ubushyuhe mu gifu.

Mvuga gufata Propylthiouracil igihe kingana iki?

Abantu benshi bafata PTU mu gihe cy'amezi 12 kugeza kuri 18 mu kuvura hyperthyroidism, nubwo igihe cyo kuvurwa kwawe giterwa n'uburwayi bwawe bwihariye n'uburyo umubiri wawe witwara ku muti. Muganga wawe azajya akurikirana urugero rw'imisemburo ya thyroïde yawe buri gihe akoresheje ibizamini by'amaraso kugirango amenye igihe kigomba gukomeza kuvurwa.

Abantu bamwe bashobora gukenera gufata PTU mu gihe gito cyo kwitegura kubagwa cyangwa kuvurwa na iodine ya radiyo. Muri ibyo bihe, kuvurwa bishobora kumara ibyumweru bike cyangwa amezi make kugeza igihe urugero rw'imisemburo ya thyroïde yawe ruhagije kugirango bakore icyo gikorwa.

Niba utwite, muganga wawe azahindura gahunda yawe yo kuvurwa yitonze mu gihe cyose utwite. Igihe gishobora guhinduka bitewe n'uburyo thyroïde yawe yitwara mu bihe bitandukanye byo gutwita, kandi muganga wawe ashobora kuguha undi muti nyuma yo kubyara.

Ni Ibihe Bikorwa Bigaragara ku Miti ya Propylthiouracil?

Kimwe n'indi miti yose, PTU ishobora gutera ibikorwa bigaragara, nubwo abantu benshi bayihanganira neza. Kumva icyo witeguye gishobora kugufasha kumva witeguye kandi ukamenya igihe wakwiyambaza umuganga wawe.

Ibikorwa bigaragara cyane muri rusange biroroshye kandi birashobora gucungwa:

• Kuruka cyangwa kurwara mu nda
• Umutwe
• Gusinzira cyangwa kunanirwa
• Kubabara mu ngingo cyangwa mu misitsi
• Guhinduka kw'uburyohe
• Urugo rwo ku ruhu cyangwa kwishima
• Kutagira umusatsi (muri rusange by'igihe gito)

Ibi bikorwa bigaragara cyane akenshi biragenda bikemuka uko umubiri wawe wimenyereza umuti mu byumweru bike bya mbere byo kuvurwa.

Ibikorwa bikomeye biragoye kubona ariko bisaba ubufasha bwihuse bw'abaganga. Ibi bikorwa bidasanzwe ariko by'ingenzi birimo:

• Ibibazo bikomeye byo mu mwijima (uruhu cyangwa amaso y'umuhondo, inkari z'umukara, kuribwa cyane mu nda)
• Umubare muto cyane w'uturemangingo tw'amaraso twera (indwara zikunze kubaho, umuriro, kubabara mu muhogo)
• Uburwayi bukomeye bwo kwibasirwa n'umubiri (kubura umwuka, kubyimba mu maso cyangwa mu muhogo)
• Ibibazo byo gupfuka amaraso (gukomereka cyangwa kuva amaraso bidasanzwe)

Muganga wawe azakugenzura neza akoresheje ibizamini by'amaraso bya buri gihe kugira ngo amenye ingaruka zikomeye hakiri kare, bikazatuma zicungwa neza cyane niziramuka zibayeho.

Ninde utagomba gufata Propylthiouracil?

PTU ntibereye buri wese, kandi muganga wawe azasuzuma neza amateka yawe y'ubuzima mbere yo kuyandika. Abantu bafite ibibazo bimwe na bimwe byo mu mwijima bagomba kwirinda PTU kuko bishobora gushimangira ibibazo byo mu mwijima bihari.

Ntabwo ugomba gufata PTU niba waragize uburwayi bukomeye bwo kwibasirwa n'umubiri mbere cyangwa niba ufite indwara zimwe na zimwe z'amaraso zigira ingaruka ku turemangingo twawe tw'amaraso twera. Muganga wawe azitonda kandi mu kuyandika niba ufite amateka y'indwara ikomeye yo mu mwijima.

Niba uri konka, muganga wawe azaganira nawe ku byago n'inyungu. Nubwo PTU ntoya ishobora kujya mu mata y'ibere, muri rusange ifatwa nk'itegura kurusha imiti yindi irwanya thyroid mugihe cyo konka, nubwo umwana wawe azakenera kugenzurwa.

Amazina ya Propylthiouracil

Muri Leta Zunze Ubumwe z'Amerika, propylthiouracil iboneka cyane nk'umuti rusange, bivuze ko mubisanzwe uzayibona yanditse gusa nka "propylthiouracil" aho kuba izina ryihariye. Ubu buryo rusange bufite akamaro kimwe n'ubwoko bw'amazina kandi mubisanzwe burahendutse.

Ibihugu bimwe bishobora kugira ubwoko bw'amazina ya PTU, ariko mubihe byinshi, uzabona uburyo rusange muri farumasi yawe. Umuti rusange urimo ibikoresho bimwe bikora kandi bikora kimwe n'ubwoko bw'amazina ayo ariyo yose.

Uburyo bwo gusimbuza Propylthiouracil

Ikindi kinyuranyo gikuru cya PTU ni methimazole (izina ry'ubucuruzi Tapazole), ni undi muti urwanya umusonga ukora kimwe. Methimazole akunda gukoreshwa ku bantu benshi kuko ashobora gufatwa rimwe ku munsi kandi ashobora kugira ingaruka nke.

Ariko, PTU iracyakoreshwa cyane mu gihe cyo gutwita, cyane cyane mu gihembwe cya mbere, kuko bidakunze gutera ubumuga bw'amavuko. Muganga wawe ashobora no guhitamo PTU niba waragize ingaruka ziterwa na methimazole cyangwa niba ufite indwara zimwe na zimwe z'umwijima aho methimazole idakwiriye.

Izindi nzira zo kuvura umusonga mwinshi zirimo kuvurwa na iodine ya radiyo na kubagwa kwa tiroyide, ariko ibi bikunze gutekerezwa nyuma yo kuvurwa n'imiti cyangwa mu bihe bidasanzwe aho imiti idakwiriye.

Ese Propylthiouracil iruta Methimazole?

Niba PTU iruta methimazole biterwa n'uko ubuzima bwawe buteye n'ibyo ukeneye mu buvuzi. Ku bantu benshi bafite umusonga mwinshi, methimazole akunda kuba uwa mbere kuko byoroshye (ifatirwa rimwe ku munsi) kandi ashobora kugira ibyago bike byo kugira ingaruka zikomeye ku mwijima.

Ariko, PTU iba nziza mu bihe bimwe na bimwe. Niba utwite, cyane cyane mu gihembwe cya mbere, PTU ikunda gukoreshwa kuko bidakunze gutera ubumuga bw'amavuko. PTU kandi ihitwamo niba waragize allergie kuri methimazole cyangwa niba ufite indwara zidasanzwe zituma methimazole idakwiriye.

Muganga wawe azatekereza ibintu nk'imyaka yawe, uko utwite, amateka yawe y'ubuvuzi, n'uburyo witwara neza ku buvuzi mugihe afata icyemezo cy'umuti ukwiriye kuri wowe. Imiti yombi ifite akamaro mu kuvura umusonga mwinshi mugihe ikoreshejwe neza.

Ibikunze Kubazwa Kuri Propylthiouracil

Ese Propylthiouracil irakwiriye ku ndwara z'umutima?

PTU ishobora gufasha abantu barwaye indwara z'umutima igihe igabanya ingaruka za hormone ya thyroïde nyinshi ku mutima. Hyperthyroïdie ishobora gutera umutima gutera vuba, umuvuduko mwinshi w'amaraso, n'izindi ndwara z'umutima, bityo kuyivura na PTU akenshi bituma ibimenyetso by'umutima birushaho kuba byiza.

Ariko, muganga wawe azakugenzura neza niba ufite indwara z'umutima zisanzwe. Bashobora gukenera guhindura imiti yawe y'umutima nk'uko urugero rwa hormone ya thyroïde rusanzwe. Buri gihe menyesha muganga wawe ku bijyanye n'indwara z'umutima mbere yo gutangira kuvurwa na PTU.

Nkwiriye gukora iki niba nanyoye propylthiouracil nyinshi ku buryo butunganye?

Niba wanyoye PTU nyinshi kuruta uko byategetswe, vugana na muganga wawe cyangwa ikigo gishinzwe ubumara ako kanya. Kunywa nyinshi bishobora gutuma urugero rwa hormone ya thyroïde yawe rugabanuka cyane, bigatuma ugira ibimenyetso nk'umunaniro ukabije, agahinda gakabije, cyangwa kumva ukonje cyane.

Ntugategereze kureba niba ibimenyetso bigaragara. N'iyo wumva umeze neza, ni ngombwa kubona inama z'abaganga kuko ingaruka za PTU nyinshi zirashobora kutagaragara ako kanya. Bika icupa ry'umuti hamwe nawe igihe ushaka ubufasha kugira ngo abaganga bamenye neza icyo wanyoye n'ingano yacyo.

Nkwiriye gukora iki niba nirengagije urugero rwa propylthiouracil?

Niba wirengagije urugero rwa PTU, nywe ako kanya wibuka, keretse igihe cyegereye urugero rwawe ruteganyijwe. Muri icyo gihe, reka urugero warengagije ukomeze gahunda yawe isanzwe. Ntukigere unywa urugero rurenze rumwe kugira ngo usimbuze urugero warengagije.

Niba ukunda kwibagirwa urugero, gerageza gushyiraho ibyibutsa kuri terefone cyangwa kunywa imiti yawe mu gihe kimwe buri munsi hamwe n'amafunguro. Kunywa imiti buri gihe bifasha gukomeza urugero rwa imiti mu mubiri wawe kugira ngo ubone ibisubizo byiza byo kuvurwa.

Nshobora kureka kunywa propylthiouracil ryari?

Ntugasize kunywa PTU utabanje kubaza muganga wawe, niyo wumva umeze neza. Guhagarika ako kanya bishobora gutuma ibimenyetso bya hyperthyroidism yawe bisubira vuba kandi bikaba byatera ikibazo giteye akaga cyitwa thyroid storm.

Muganga wawe azagabanya buhoro buhoro urugero rwawe igihe kigeze cyo guhagarika imiti, akenshi nyuma y'amezi 12 kugeza kuri 18 y'urugero rwa hormone ya thyroid ihagaze neza. Bazakomeza gukurikirana imikorere ya thyroid yawe binyuze mu igeragezwa ry'amaraso kabone niyo wahagaritse imiti kugirango barebe ko thyroid yawe ikomeza guhagarara neza.

Nshobora kunywa inzoga nkanwa Propylthiouracil?

Nubwo nta sano riri hagati ya PTU n'inzoga, ni byiza kugabanya kunywa inzoga mugihe unywa iyi miti. PTU n'inzoga byombi bishobora kugira ingaruka ku mwijima wawe, kandi kubivanga bishobora kongera ibyago byo kurwara umwijima.

Niba uhisemo kunywa inzoga, bikore mu rugero ruto kandi ubiganireho na muganga wawe. Bashobora kugusaba gukora igeragezwa ry'imikorere y'umwijima kenshi kugirango barebe ubuzima bw'umwijima wawe. Jya uhora ukuriye umuganga wawe ku bijyanye no kunywa inzoga kugirango batange ubuvuzi bwiza kubijyanye n'uko ubuzima bwawe bumeze.