Selegiline Transdermal ni iki: Ibikoreshwa, Urutonde rw'imiti, Ingaruka ziterwa n'iyo miti n'ibindi

Selegiline transdermal ni umuti wandikirwa na muganga ukoreshwa mu gukoresha ibishishwa byo ku ruhu kugira ngo utange imiti unyuze mu ruhu kugira ngo uvure indwara yo kwiheba ikabije. Uyu muti wihariye ukoreshwa mu gukoresha ibishishwa byo ku ruhu ukora mu buryo butandukanye n'ibindi binini kuko wibanda mu gihe cyo gukora mu nzira yo mu gifu, ukemerera umuti kwinjira mu maraso yawe unyuze mu ruhu rwawe.

Ibishishwa byo ku ruhu bikubiye mu cyiciro cy'imiti yitwa MAO inhibitors, ikora mugukongeza imisemburo imwe n'imwe yo mu bwonko ifasha kunoza imyumvire yawe. Ushobora kumenya uyu muti ku izina ry'ubucuruzi rya Emsam, kandi igenewe kwambarwa ku ruhu rwawe amasaha 24 mbere yo gusimburwa n'ibishishwa bishya.

Selegiline Transdermal ikoreshwa mu iki?

Ibishishwa bya Selegiline transdermal byandikirwa cyane cyane kuvura indwara yo kwiheba ikabije mu bantu bakuru. Muganga wawe ashobora kugusaba uyu muti iyo ibindi binini byo kurwanya kwiheba bitagukoreye neza cyangwa iyo wagaragaje ingaruka ziterwa n'imiti yo kunywa.

Ubu buryo bwo gukoresha ibishishwa byo ku ruhu bushobora gufasha cyane niba ugira ikibazo cyo kumira ibinini cyangwa niba ukunda uburyo bwo kuvurwa rimwe ku munsi. Abaganga bamwe kandi babitekereza iyo abarwayi bakeneye umuti ukora mu buryo butandukanye n'ubwoko busanzwe bwo kurwanya kwiheba nka SSRIs cyangwa SNRIs.

Uburyo bwo gukoresha ibishishwa byo ku ruhu butanga umuti uhamye kandi ukomeza umunsi wose. Uku gutanga imiti guhoraho gushobora gufasha gukomeza urwego rwo hejuru rw'umuti mu mubiri wawe ugereranije no kunywa ibinini inshuro nyinshi ku munsi.

Selegiline Transdermal ikora ite?

Selegiline transdermal ikora muguhagarika enzyme yitwa monoamine oxidase (MAO) mu bwonko bwawe. Iyi enzyme isanzwe isenya imisemburo y'ingenzi igenga imyumvire nka serotonin, norepinephrine, na dopamine.

Mu kwirinda iyi enzyme, urupapuro rutuma imisemburo y'ubwonko y'"umunezero" yiyongera kandi ikaguma ikora igihe kirekire. Bitekereze nk'ugufunga umwobo wo kuvomera muri bati - amazi (imisemburo y'ubwonko) ashobora kwiyongera ku rwego rwo hejuru, rukagirira akamaro.

Urupapuro rutanga umuti unyuze mu ruhu rwawe ku kigereranyo kigenzurwa mu masaha 24. Ibi bifasha kugumana urwego rwo hejuru rw'umuti mu maraso yawe, ibyo bishobora gutuma imyumvire ihinduka neza ugereranije n'ibibazo by'imitekerereze rimwe na rimwe bigaragara ku miti inyobwa.

Ibi bifatwa nk'umuti wo kurwanya ubwoba ukomeye, usanzwe ufata ibyumweru byinshi kugira ngo ugaragaze ingaruka zawo zose. Uburyo bwo gutanga umuti unyuze mu ruhu buratandukanye mu miti yo kurwanya ubwoba, kuko akenshi ishobora gukoreshwa ifite imbogamizi nkeya z'imirire ugereranije n'imiti yo kurwanya ubwoba inyobwa.

Nagomba Gufata Uyu Muti Ute?

Shyira urupapuro rwa selegiline ku ruhu rwawe rwo hejuru, amaboko, cyangwa ibibero byumye, bitagira umusatsi rimwe mu masaha 24. Hitamo ahantu hatandukanye buri munsi kugira ngo wirinde kurakara kw'uruhu, kandi wirinde ahantu imyenda ishobora gukoraho urupapuro.

Mbere yo gushyiraho urupapuro rushya, kura urwa kera hanyuma woge ahantu hose neza n'isabune n'amazi. Kanda urupapuro rushya neza mu gihe cy'amasegonda 30 kugira ngo wemeze ko ruzamuka neza ku ruhu rwawe.

Ushobora kwiyuhagira, koga, cyangwa koga mu gihe wambaye urupapuro, ariko wirinde ibizenga bishyushye, saunas, cyangwa kugaragaza izuba ryinshi ku gice cy'urupapuro. Ubushyuhe bushobora kongera umuti winjira mu ruhu rwawe, bishobora gutera ingaruka ziterwa n'umuti.

Gerageza gushyira urupapuro rwawe mu gihe kimwe buri munsi kugira ngo ugumane urwego rwo hejuru rw'umuti. Niba urupapuro ruvuyeho, shyiraho urushya ako kanya hanyuma ukomeze gahunda yawe isanzwe umunsi ukurikira.

Nagomba Gufata Uyu Muti Igihe Kingana Gite?

Abantu benshi bakeneye gukoresha ibipande bya selegiline transdermal mu mezi menshi kugeza ku mwaka cyangwa kurenza, bitewe n'uburyo bitwara ku miti. Muganga wawe akenshi azashaka ko ukomeza gufata umuti byibuze amezi 6-12 nyuma yuko ibimenyetso byo kwiheba byawe bigabanuka.

Muri rusange bifata ibyumweru 4-6 kugirango umenye neza akamaro k'uyu muti, nubwo abantu bamwe bashobora gutangira kumva barushaho kumera neza mbere y'igihe. Ntukacike intege niba utabonye ibisubizo ako kanya - imiti igabanya kwiheba akenshi ikora buhoro buhoro.

Muganga wawe azakurikiza uko urimo utera imbere kandi ashobora guhindura gahunda yawe yo kuvurwa bitewe n'uburyo urimo witwara. Abantu bamwe bashobora gukenera gukoresha ibipande igihe kirekire kugirango bagumane ubuzima bwabo bwo mu mutwe, mu gihe abandi bashobora kubireka nyuma y'igihe gito cyo guhagarara.

Ntuzigere uhagarika gukoresha ibipande ako kanya utabanje kuvugana na muganga wawe. Guhagarika ako kanya bishobora gutera ibimenyetso byo kuva mu miti kandi bishobora gutuma kwiheba kwawe gusubira.

Ni Ibihe Bikorwa Bigaragara Byo Ku Ruhande Bya Selegiline Transdermal?

Kimwe n'indi miti yose, selegiline transdermal ishobora gutera ibikorwa bigaragara ku ruhande, nubwo atari buri wese ubyumva. Ibikorwa bigaragara ku ruhande bisanzwe ni bike kandi akenshi birushaho gukira uko umubiri wawe wimenyereza umuti.

Dore ibikorwa bigaragara ku ruhande ushobora guhura nabyo cyane, dutangiriye ku bisanzwe:

• Urubavu rw'uruhu, gutukura, cyangwa kuribwa aho ushyira ipande
• Umutwe no kuribwa umutwe
• Kugorwa no gusinzira cyangwa inzozi zidasanzwe
• Isesemi cyangwa kuribwa mu nda
• Impiswi cyangwa guhagarara kw'amara
• Umunwa wumye
• Kunanirwa cyangwa kumva unaniwe cyane

Ibi bikorwa bigaragara ku ruhande bisanzwe bikunda kugabanuka mu byumweru bike bya mbere byo kuvurwa. Niba urubavu rw'uruhu rukomeje, gerageza guhinduranya ahantu ushyira ipande kenshi.

Abantu bamwe bashobora guhura n'ibikorwa bigaragara ku ruhande bikomeye bisaba ubufasha bwihuse bwa muganga. Nubwo ibi bidakunze kubaho, ni ngombwa kubimenya:

• Umuvuduko ukabije w'amaraso ufite ibimenyetso nk'umutwe ukabije, kubabara mu gituza, cyangwa impinduka mu mbono
• Ibimenyetso bya syndrome ya serotonin: urujijo, umutima utera cyane, umuriro mwinshi, cyangwa imitsi y'umubiri ikakara
• Impinduka zidasanzwe mu myifatire cyangwa imyitwarire, harimo n'ibitekerezo byo kwigirira nabi
• Urugero rukabije rw'uburwayi bwo mu mubiri rufite ibibazo byo ku ruhu, kubyimba, cyangwa guhumeka bigoye
• Guta igihagararo cyangwa isereri rikomeye iyo uhagurutse

Vugana n'umuganga wawe ako kanya niba ubonye izi ngaruka zikomeye. Abantu benshi boroherwa na selegiline transdermal, ariko kuguma maso kuri ibi bimenyetso by'imburabuzi bifasha mu kwirinda.

Ninde utagomba gufata Selegiline Transdermal?

Selegiline transdermal ntibishoboka kuri buri wese, kandi umuganga wawe azasuzuma neza amateka yawe mbere yo kuyikoresha. Uburwayi runaka n'imiti bishobora guteza ingaruka zikomeye hamwe n'iyi patch.

Ntabwo ugomba gukoresha selegiline transdermal niba ufite kimwe muri ibi bibazo:

• Gukoresha ibindi byongera ibyishimo, cyane cyane SSRIs, SNRIs, cyangwa izindi MAO inhibitors
• Uburwayi bukomeye bw'umutima cyangwa umuvuduko ukabije w'amaraso utagenzurwa
• Amateka ya stroke cyangwa ibibyimba byo mu bwonko
• Uburwayi bukomeye bw'umwijima cyangwa impyiko
• Uburwayi bwo kurya nk'anorexia cyangwa bulimia
• Uburwayi bwa bipolar (keretse niba bikurikiranwa byihariye)
• Allergie kuri selegiline cyangwa ibice bya patch

Ibi bibazo bishobora kwiyongera hamwe no gukoresha selegiline cyangwa kongera ibyago byo kugira ingaruka zikomeye. Umuganga wawe akeneye aya makuru kugirango akurinde.

Byongeye kandi, imiti imwe igomba guhagarikwa mbere yo gutangira selegiline transdermal. Igihe cyo gutegereza hagati y'imiti ni ngombwa ku mutekano wawe:

• Imiti myinshi ivura depression isaba ikiruhuko cy'ibyumweru 2 mbere yo gutangira selegiline
• Fluoxetine (Prozac) isaba ikiruhuko cy'ibyumweru 5 kubera ingaruka zayo zirambye
• Imiti ivura ububabare irimo meperidine, tramadol, cyangwa methadone
• Imiti imwe na imwe yo gukorora no gufata ibicurane irimo dextromethorphan
• Imiti itera imbaraga ikoreshwa mu kuvura ADHD

Muganga wawe azakora gahunda yo guhindura imiti mu buryo bwizewe niba uhindura kuva ku yindi miti ivura depression. Ntukigere uhagarika umuti wawe urimo cyangwa utangira selegiline utabanje kugisha inama umuganga.

Izina ry'ubucuruzi rya Selegiline Transdermal

Izina ry'ubucuruzi rya selegiline transdermal ni Emsam, ikorwa na Somerset Therapeutics. Ubu ni bwo buryo bumwe bwemewe na FDA bwa selegiline transdermal buboneka muri Leta Zunze Ubumwe z'Amerika.

Uduce twa Emsam tuza mu mbaraga zitandukanye eshatu: 6 mg/amasaha 24, 9 mg/amasaha 24, na 12 mg/amasaha 24. Muganga wawe azagena imbaraga zikwiriye kuri wowe bitewe n'ibyo ukeneye n'uburyo witwara ku miti.

Bitandukanye n'ubwoko bwa generic bwa imiti myinshi, ubu ntakindi gice cya generic cya selegiline transdermal kiboneka. Ibi bivuze ko uzabona Emsam y'izina ry'ubucuruzi iyo umuti wawe wanditswe.

Uburyo bwa Selegiline Transdermal

Niba selegiline transdermal itagukwiriye, hari imiti myinshi ivura depression ishobora gufasha kuvura indwara ya depression ikomeye. Muganga wawe ashobora gutekereza kuri izi nzira bitewe n'ibimenyetso byawe byihariye n'amateka yawe y'ubuzima.

Andi mashuri y'imiti ivura depression akora mu buryo butandukanye arimo:

• SSRIs nka sertraline (Zoloft) cyangwa escitalopram (Lexapro)
• SNRIs nka venlafaxine (Effexor) cyangwa duloxetine (Cymbalta)
• Imiti idasanzwe ivura depression nka bupropion (Wellbutrin) cyangwa mirtazapine (Remeron)
• Imiti ya tricyclic ivura depression mu bihe bimwe na bimwe
• Izindi MAO inhibitors mu buryo bwo kunywa, nubwo izi zisaba kubahiriza cyane ibyo kurya

Buri kimwe muri ibi bisubizo gifite inyungu zacyo n'ingaruka zishobora kubaho. Muganga wawe ashobora kugufasha gupima ibyiza n'ibibi bya buri kimwe.

Ubuvuzi butakoresha imiti nabwo bushobora kugira akamaro bwonyine cyangwa buvanze n'imiti igabanya ububabare. Ibi bishobora kuba harimo ubuvuzi bwo mu mutwe, ubundi buryo bwo kuvura indwara zo mu mutwe, cyangwa impinduka mu mibereho nk'imyitozo ngororamubiri ya buri gihe n'uburyo bwo kugabanya umunaniro.

Ese Selegiline Transdermal iruta izindi miti igabanya ububabare?

Selegiline transdermal ntabwo ari ngombwa ko iruta izindi miti igabanya ububabare, ariko itanga inyungu zidasanzwe ku bantu bamwe na bamwe. Uburyo bwo gukoresha ibishishwa bitanga imiti ihoraho kandi bishobora gukora iyo izindi miti igabanya ububabare zitagize icyo zikora.

Ugereranije n'ibiyobyabwenge bya MAO byo mu kanwa, selegiline transdermal isaba ibiribwa bike, cyane cyane ku bipimo bike. Ibi bituma bikorera neza mu buzima bwa buri munsi mugihe bigitanga inyungu zo guhagarika MAO.

Uburyo bwo gutanga imiti binyuze mu ruhu bushobora gufasha cyane niba ufite ibibazo byo mu nda hamwe n'imiti yo mu kanwa cyangwa ukunda gukoresha imiti rimwe ku munsi. Abantu bamwe kandi basanga imitsi ihoraho ifasha kugabanya impinduka z'amarangamutima rimwe na rimwe ziboneka mu binini.

Ariko, izindi miti igabanya ububabare nka SSRIs cyangwa SNRIs zishobora kuba amahitamo meza ya mbere ku bantu benshi kuko ntigira imikoranire myinshi y'imiti kandi ntisaba ingamba zimwe. Muganga wawe azatekereza ishusho yawe yuzuye y'ubuvuzi mugihe asaba ubuvuzi bwiza kuri wewe.

Ibikunze kubazwa kuri Selegiline Transdermal

Ese Selegiline Transdermal irakwiriye indwara z'umutima?

Selegiline transdermal isaba gutekereza neza niba ufite ibibazo by'umutima. Nubwo bishobora kuba byiza kuruta ibiyobyabwenge bya MAO byo mu kanwa kubera indwara zimwe z'umutima, birashobora kandi kugira ingaruka ku mitsi y'amaraso n'umutima.

Muganga wawe azagomba gusuzuma uburwayi bw'umutima bwawe mbere yo kugena uyu muti. Bashobora kugusaba gutangira n'urugero ruto hanyuma bagakurikirana umuvuduko w'amaraso yawe n'umuvuduko w'umutima wawe cyane mugihe uvurwa.

Niba ufite indwara ikomeye y'umutima, umuvuduko w'amaraso mwinshi utagenzurwa, cyangwa amateka yo gufatwa n'umutima cyangwa sitiroko, muganga wawe ashobora kugusaba undi muti uvura depression. Buri gihe menyesha umuganga wawe ibibazo byose by'umutima mbere yo gutangira kuvurwa.

Nkwiriye gukora iki niba nshizeho selegiline transdermal ku buryo butunganye?

Niba ushyizeho ibirenze kimwe cyangwa ukoresheje urugero rurenze urwanditse, vana ako gapaki ako kanya kandi uvugishe muganga wawe cyangwa ikigo gishinzwe kugenzura uburozi ako kanya. Ntukegere kureba niba ibimenyetso bigaragara.

Ibimenyetso bya selegiline nyinshi birimo kubabara umutwe cyane, umuvuduko mwinshi w'amaraso, umutima wihuta, urujijo, cyangwa kumva uhangayitse cyane. Ibi bimenyetso birashobora kuba bikomeye kandi bisaba ubufasha bwihutirwa bw'abaganga.

Ntugasabe gushyiraho ibipaki byinshi kugirango wongere ingaruka, niyo utiyumva neza. Uyu muti ukeneye igihe cyo gukora, kandi gukoresha byinshi kuruta uko byanditswe birashobora kuba bibi aho kuba byiza.

Nkwiriye gukora iki niba nciweho urugero rwa selegiline transdermal?

Niba wibagiwe gushyiraho agapaki gashya, shyiraho ako kanya wibuka, hanyuma ukomeze gahunda yawe isanzwe ku munsi ukurikira. Ntukagashyireho ibipaki bibiri kugirango usubize urugero rwatanzwe.

Niba urengereje amasaha 12 utarashyiraho agapaki kawe, gashyireho mugihe wibuka hanyuma ushyireho agapaki gakurikira mugihe cyawe gisanzwe kumunsi ukurikira. Ibi bifasha gukomeza urugero rwa imiti ihwanye muri sisitemu yawe.

Gerageza gushyiraho alarume ya buri munsi cyangwa kwibutswa kuri terefone yawe kugirango bigufashe kwibuka guhindura agapaki kawe. Guhora ni ngombwa kugirango umuti ukore neza.

Nshobora guhagarika ryari gufata selegiline transdermal?

Ugomba guhagarika gukoresha selegiline transdermal uyobowe na muganga wawe, kabone n'iyo wumva umeze neza cyane. Guhagarika ako kanya bishobora gutera ibimenyetso byo kuva mu kiyobyabwenge kandi bishobora gutuma agahinda kawe kagaruka.

Muganga wawe akenshi azagusaba kugabanya urugero rwawe buhoro buhoro aho guhagarika byose icyarimwe. Ubu buryo, bwitwa tapering, bufasha umubiri wawe guhuza kandi bugabanya ibyago byo kuva mu kiyobyabwenge.

Abaganga benshi basaba gukomeza kuvura agahinda k'umutima byibuze amezi 6-12 nyuma y'uko ibimenyetso byawe bigabanuka. Abantu bamwe bashobora gukenera kuvurwa igihe kirekire kugira ngo bagumane ubuzima bwabo bwo mu mutwe, kandi ibyo ni ibisanzwe.

Nshobora kunywa inzoga nkorera selegiline transdermal?

Nibyiza kwirinda inzoga mugihe ukoresha selegiline transdermal patches. Inzoga irashobora kongera ibyago byo kugira ingaruka zirimo isereri, gusinzira, no kugorana kwibanda.

Inzoga irashobora kandi gukomeza ibimenyetso byo kwiheba no kubangamira imikoreshereze yawe. Ndetse n'utuntu duto dushobora kugira ingaruka ku buryo umuti ukora neza cyangwa ugatuma ingaruka zigaragara cyane.

Niba uhisemo kunywa rimwe na rimwe, ganira na muganga wawe kubijyanye n'urugero rushobora kuba rukurwanye. Barashobora gutanga ubuyobozi bwihariye bushingiye ku miterere yawe yihariye n'indi miti ushobora kuba ufata.