Cutaneous T-cell lymphoma (CTCL) is a rare form of cancer. It starts in a type of white blood cell called a T cell, which is part of your body's immune system, the part that fights off infections. In CTCL, these T cells become abnormal and start attacking the skin instead of germs.
This attack shows up as skin problems, such as:
There are different types of CTCL. The most common type is called mycosis fungoides. A less common type is Sezary syndrome, which causes redness all over the body.
Some types of CTCL, like mycosis fungoides, develop slowly over time. Others are more aggressive. The type of CTCL you have helps doctors decide the best treatment plan.
Treatment options might include:
CTCL is one kind of lymphoma. Lymphoma is a general term for cancers of the lymphatic system, a part of the body's immune system. There are many different types of lymphoma, and CTCL is one of the non-Hodgkin's lymphomas.
Cutaneous T-cell lymphoma (CTCL) is a type of skin cancer. It's important to know the signs so you can get help early. Here are some common symptoms:
Skin patches: You might notice round areas on your skin. These spots could be raised, like little bumps, or scaly, like dry, flaky skin. They often itch.
Changes in skin color: Some areas of skin might look lighter than the surrounding skin.
Skin lumps: You might develop lumps under your skin. These lumps can sometimes break open.
Swollen lymph nodes: Lymph nodes are small, bean-shaped glands throughout your body. If you have CTCL, these nodes might get bigger.
Hair loss: In some cases, CTCL can cause hair loss.
Thickened skin: The skin on your palms and soles (the bottoms of your feet) might become thicker than usual.
Widespread rash: A red rash that covers most of your body and itches intensely can also be a sign of CTCL.
If you notice any of these skin changes, it's important to see a doctor right away. Early diagnosis and treatment are key to managing this condition effectively. These symptoms can also be caused by other skin conditions, so a doctor can properly diagnose the problem.
Cutaneous T-cell lymphoma (CTCL) is a skin cancer, but we don't fully understand what causes it. Cancer happens when cells in the body start to grow and multiply out of control. This uncontrolled growth happens because of changes, called mutations, in the DNA inside the cells. DNA is like a set of instructions that tells the cells what to do. When DNA is mutated, it gives the cells faulty instructions, telling them to grow and divide much faster than normal. This creates a large number of abnormal cells.
In CTCL, these mutations affect a type of immune cell called a T cell. T cells are important parts of our immune system, helping us fight off infections and diseases. Normally, T cells help protect our bodies. However, in CTCL, the mutated T cells turn against the body and attack the skin instead of fighting off germs. Scientists don't yet know exactly why these T cells turn on the skin.
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