Acute Lymphocytic Leukemia

Kenza ye lymphocytic yakapinza (ALL) rudzi rwekenza yeropa nemapfupa emo — tishu inopfumbuka iri mukati memapfupa kwaanoitwa ma cell eropa.\n\nShoko rokuti "yakapinza" mukenza ye lymphocytic yakapinza rinobva pakuti chirwere ichi chinokurumidza kuitika uye chinoita ma cell eropa asina kukura, panzvimbo pema cell akakura. Shoko rokuti "lymphocytic" mukenza ye lymphocytic yakapinza rinoreva ma cell eropa machena anonzi lymphocytes, ayo ALL inokanganisa. Kenza ye lymphocytic yakapinza inozivikanwawo sekenza ye lymphoblastic yakapinza.\n\nKenza ye lymphocytic yakapinza ndiyo rudzi rwakajairika rwekenza muvana, uye kurapwa kunounza mukana wakanaka wekurapa. Kenza ye lymphocytic yakapinza inogonawo kuitika kune vakuru, kunyange mukana wekurapa uchideredzwa zvikuru.

'Zviratidzo nezvikonzero zvekenza ye lymphocytic yakapinza zvinogona kusanganisira: Kubuda ropa kubva kumeno\nKurwadziwa kwemwongo\nFevha\nKuwanikwa kwehutachiona\nKubuda ropa kwemhuno kazhinji kana kwakanyanya\nZvipembere zvinokonzerwa nekuzvimba kwe lymph nodes mukati nekumativi kwemutsipa, armpits, mudumbu kana groin\nGanda rakatsvuka\nKushomeka kwemhepo\nKushaya simba, kuneta kana kudzikira kwesimba zvakanyanya Rongai nhau nechikurama chenyu kana chiremba wemwana wenyu kana mukaona chero zviratidzo nezvikonzero zvinogara zvichikunetsei. Zviratidzo zvizhinji nezvikonzero zvekenza ye lymphocytic yakapinza zvinoita se zvechirwere chemafuru. Zvisinei, zviratidzo nezvikonzero zvemafuru zvinopera pakupedzisira. Kana zviratidzo nezvikonzero zvisingaperi sezvakatarisirwa, rongai nhau nechikurama chenyu.'

Enda kuonana nachiremba wako kana nachiremba wemwana wako kana ukaona zviratidzo nezvimwe zviratidzo zvinogara zvichikunetseka.

Zviratidzo nezvimwe zviratidzo zve leukemia ye lymphocytic yakapinza zvinofananidzwa nezvechirwere chemafuru. Zvisinei, zviratidzo nezvimwe zviratidzo zvemafuru zvinopera pakupedzisira. Kana zviratidzo nezvimwe zviratidzo zvisina kuvanduka sezvaitarisirwa, enda kuonana nachiremba wako.

Kenza ye lymphocytic leukemia inoitika kana sero remunwe wemwongo richikura kuchinja (mutations) muzvinhu zvaro zve genetic kana DNA. DNA yesero ine mirairo inoudza sero kuti riite sei. Kazhinji, DNA inoudza sero kuti rikure nekukurumidza uye kuti rife panguva yakatarwa. Mukenza ye lymphocytic leukemia, mutations inoudza sero remunwe wemwongo kuti rirambe richikura uye richikamukana.\n\nKana izvi zvikaitika, kugadzirwa kwesero neropa kunova kunze kwekudzora. Mwongo wemwongo unogadzira masero asina kukura ayo anoita masero machena eropa anokonzera kenza anonzi lymphoblasts. Aya masero asina kunaka haakwanisi kushanda zvakanaka, uye anogona kuunganidzwa uye kukanda masero ane hutano.\n\nHazvina kujeka kuti chii chinokonzera mutations yeDNA inogona kutungamira kukenza ye lymphocytic leukemia.

Zvinhu zvinogona kuwedzera njodzi yekenza ye lymphocytic yakapinza zvinosanganisira:

• Kurapwa kwekenza kare. Vana nevakuru vakamboita marapirwo chaiwo ekemotherapy uye kurapwa ne radiation nekuda kwemamwe marudzi ekenza vanogona kunge vane njodzi yakawedzera yekuwana kenza ye lymphocytic yakapinza.
• Kuonekwa ne radiation. Vanhu vanowanikwa ne radiation yakakwirira kwazvo, senge avo vakapona tsaona yereactori yenyukireya, vane njodzi yakawedzera yekuwana kenza ye lymphocytic yakapinza.
• Zvirwere zve genetic. Zvirwere zve genetic zvakaita seDown syndrome, zvinosanganisirwa nenjodzi yakawedzera yekenza ye lymphocytic yakapinza.

Kuongororwa kwemapfupa emusoro Wedzera mufananidzo Vhara Kuongororwa kwemapfupa emusoro Kuongororwa kwemapfupa emusoro Mukutsvaga ropa kubva mumapfupa emusoro, mushandi wehutano anoshandisa tsono yakatetepa kubvisa huwandu hudiki hweropa kubva mumapfupa emusoro. Kazhinji inotorwa kubva panzvimbo iri kumashure kwemapfupa ehip, inozivikanwawo se pelvis. Kuongororwa kwemapfupa emusoro kunowanzoitwa panguva imwe chete. Maitiro aya echipiri anobvisa chidimbu chidiki che tishu yemumapfupa nemapfupa emusoro ari mukati. Kuisa tsono muchiuno, kunziwo spinal tap Wedzera mufananidzo Vhara Kuisa tsono muchiuno, kunziwo spinal tap Kuisa tsono muchiuno, kunziwo spinal tap Panguva yekuisa tsono muchiuno, kunziwo spinal tap, kazhinji unovata parutivi rwako nemaoko ako akakotama kusvika pachipfuva chako. Ipapo tsono inoiswa muchikamu chechinyorwa chekumashure kwako kuti iunganidze cerebrospinal fluid yekuongororwa. Kuongororwa nekuita zvinhu zvinoshandiswa kuziva acute lymphocytic leukemia zvinosanganisira: Kuongororwa kweropa. Kuongororwa kweropa kunogona kuratidza huwandu hwakawanda kana hudiki hwema cell machena eropa, kushomeka kwema cell matsvuku eropa, uye kushomeka kwema platelets. Kuongororwa kweropa kunogonawo kuratidza kuvapo kwema blast cells - ma cell asina kukura anowanikwa mumapfupa emusoro. Kuongororwa kwemapfupa emusoro. Panguva yekutsvaga ropa kubva mumapfupa emusoro ne biopsy, tsono inoshandiswa kubvisa sampuli yeropa kubva mumapfupa ehip kana mumapfupa echidzitiro. Sampuli yacho inotumirwa ku laboratori yekuongororwa kuti ione ma cell e leukemia. Madokota vari mu laboratori vachaisa ma cell eropa mumapoka chaiwo zvichienderana nehukuru, chimiro, nezvimwe zvinhu zve genetic kana molecular. Vanotarisawo kuchinja kwakati kwemu cell ye cancer uye vanoona kana ma cell e leukemia akatanga kubva ku B lymphocytes kana T lymphocytes. Ruzivo urwu runobatsira chiremba wako kuita hurongwa hwekurapa. Kuongororwa kwe mifananidzo. Kuongororwa kwemifananidzo senge X-ray, computerized tomography (CT) scan kana ultrasound scan kunogona kubatsira kuona kana cancer yakapararira kuuropi ne spinal cord kana kune dzimwe nzvimbo dzemuviri. Kuongororwa kwe spinal fluid. Kuongororwa kwe lumbar puncture, kunziwo spinal tap, kunogona kushandiswa kuunganidza sampuli yespinal fluid - fluid inopoteredza uropi ne spinal cord. Sampuli yacho inongororwa kuti ione kana ma cell e cancer akapararira kuspinal fluid. Kuona zvaunofungidzirwa nachiremba wako anoshandisa ruzivo rwakaunganidzwa kubva mukuongororwa uku nekuita zvinhu kuti aone zvaunofungidzirwa nachiremba wako uye asarudze sarudzo dzako dzekurapa. Mamwe marudzi e cancer anoshandisa nhanho dzenhamba kuratidza kuti cancer yakapararira sei, asi hakuna nhanho dze acute lymphocytic leukemia. Panzvimbo pezvo, kukomba kwezvinhu zvako kunotsanangurwa ne: Rudzi rwe lymphocytes rinosanganisirwa - B cells kana T cells Kuchinja kwakati kwe genetic kuri muma cell ako e leukemia Zera rako Mhedzisiro yekuongororwa kwe laboratori, senge huwandu hwema cell machena eropa akaonekwa mu sampuli yeropa Kutarisirwa paMayo Clinic Timu yedu yekutarisira ye Mayo Clinic inogona kukubatsira nezvinetso zvako zvehutano zvine chekuita ne acute lymphocytic leukemia Tanga pano Zvimwe Zivo Kutarisirwa kwe acute lymphocytic leukemia paMayo Clinic Bone marrow biopsy CT scan Lumbar puncture (spinal tap) Ultrasound X-ray Ratidza rumwe ruzivo rwakabatana

Mukuru wese, kurapwa kwechirwere che leukemia ye lymphocytic yakapinza kunowira muzvikamu zvakasiyana-siyana:

• Kurapwa kwekubatanidza. Kunonziwo kurapwa mushure mekupora, chikamu ichi chekurapwa chinangwa chekuparadza chero leukemia inosara mumuviri.
• Kurapwa kwekutsigira. Chikamu chechitatu chekurapwa chinodzivirira masero e leukemia kuti arege kukura zvakare. Kurapwa kunoshandiswa muchikamu chino kazhinji kunoitirwa pane zviduku zvakanyanya kwenguva yakareba, kazhinji makore.
• Kurapwa kwekudzivirira kune spinal cord. Panguva yega yega yekurapwa, vanhu vane leukemia ye lymphocytic yakapinza vanogona kugamuchira kurapwa kuwedzerwa kuparadza masero e leukemia ari munhevedzano yetsinga. Munzira iyi yekurapwa, mishonga yechemotherapy kazhinji inodonhedzwa zvakananga mumvura inofukidza spinal cord.

Zvichienderana nemamiriro ako, zvikamu zve kurapwa kwe leukemia ye lymphocytic yakapinza zvinogona kusvika kumakore maviri kusvika matatu.

Kurapwa kunogona kusanganisira:

• Chemotherapy. Chemotherapy, inoshandisa mishonga kuuraya masero ecanser, kazhinji inoshandiswa se kurapwa kwekutanga kwevana nevakuru vane leukemia ye lymphocytic yakapinza. Mishonga yeChemotherapy inogona kushandiswawo muzvikamu zvekubatanidza nekutsigira.
• Kurapwa kwakatarwa. Kurapwa kwemishonga yakatarwa kunotarisa pane zvikanganiso zvakakosha zviripo mukati memasero ecanser. Nekuvhara zvikanganiso izvi, kurapwa kwemishonga yakatarwa kunogona kuita kuti masero ecanser afe. Masero ako e leukemia achaongororwa kuti uone kana kurapwa kwakatarwa kungakubatsira. Kurapwa kwakatarwa kunogona kushandiswa uri woga kana kusanganiswa ne chemotherapy yekurapwa kwekutanga, kurapwa kwekubatanidza kana kurapwa kwekutsigira.
• Kurapwa kweRadiation. Kurapwa kweRadiation kunoshandisa mabhuru akasimba, akadai se X-rays kana mapurotoni, kuuraya masero ecanser. Kana masero ecanser apamhamha kune central nervous system, chiremba wako anogona kukurudzira kurapwa kweRadiation.
• Kusimudzwa kwemafuta emusana. Kusimudzwa kwemafuta emusana, kunonziwo kusimudzwa kwemasero estem, kunogona kushandiswa se kurapwa kwekubatanidza kana kurapa relapse kana ikaitika. Maitiro aya anoita kuti munhu ane leukemia agadzire mafuta emusana ane hutano nekutsiva mafuta emusana ane leukemia nemafu emusana asina leukemia kubva kune munhu ane hutano.

Kusimudzwa kwemafuta emusana kunotanga nehuwandu hwakawanda hwe chemotherapy kana radiation kuparadza chero mafuta emusana anogadzira leukemia. Mafuta emusana anozotsiviwa nemafu emusana kubva kumupi ane mukurumbira (allogeneic transplant).

• Kuita masero ekuzvidzivirira kurwisa leukemia. Kurapwa kwakasarudzika kunonzi chimeric antigen receptor (CAR) -T cell therapy inotora masero eT emuviri wako anorwisa zvirwere, inoaita kuti arwise cancer uye inoawedzera kumashure mumuviri wako.

CAR-T cell therapy inogona kunge iri sarudzo yevana nevakuru vechidiki. Inogona kushandiswa pakurapwa kwekubatanidza kana kurapa relapse.

• Kuongororwa kwezvipatara. Kuongororwa kwezvipatara ndizvo zviitiko zvekuyedza kurapwa kwetsva ye cancer uye nzira itsva dzokushandisa kurapwa kuripo. Kunyangwe kuongororwa kwezvipatara kuchikupei iwe kana mwana wako mukana we kuyedza kurapwa kwepamusoro-soro re cancer, zvakanakira nezvinokuvadza zvekurapwa zvinogona kunge zvisina chokwadi. Kurukurai zvakanakira nezvinokuvadza zvekuongororwa kwezvipatara nachiremba wako.

Kusimudzwa kwemafuta emusana. Kusimudzwa kwemafuta emusana, kunonziwo kusimudzwa kwemasero estem, kunogona kushandiswa se kurapwa kwekubatanidza kana kurapa relapse kana ikaitika. Maitiro aya anoita kuti munhu ane leukemia agadzire mafuta emusana ane hutano nekutsiva mafuta emusana ane leukemia nemafu emusana asina leukemia kubva kune munhu ane hutano.

Kusimudzwa kwemafuta emusana kunotanga nehuwandu hwakawanda hwe chemotherapy kana radiation kuparadza chero mafuta emusana anogadzira leukemia. Mafuta emusana anozotsiviwa nemafu emusana kubva kumupi ane mukurumbira (allogeneic transplant).

Kuita masero ekuzvidzivirira kurwisa leukemia. Kurapwa kwakasarudzika kunonzi chimeric antigen receptor (CAR) -T cell therapy inotora masero eT emuviri wako anorwisa zvirwere, inoaita kuti arwise cancer uye inoawedzera kumashure mumuviri wako.

CAR-T cell therapy inogona kunge iri sarudzo yevana nevakuru vechidiki. Inogona kushandiswa pakurapwa kwekubatanidza kana kurapa relapse.

Vakuru vakwegura, vakadai se avo vane makore anopfuura makumi matanhatu nemashanu, vanowanzoona matambudziko akawanda kubva pakurapwa. Uye vakuru vakuru kazhinji vane prognosis yakaipa kupfuura vana vanorapwa leukemia ye lymphocytic yakapinza.

Kurukurai sarudzo dzako nachiremba wako. Zvichienderana nehutano hwako hwese nezvinangwa zvako nezvaunoda, unogona kusarudza kuita kurapwa kwe leukemia yako.

Vamwe vanhu vanogona kusarudza kurega kurapwa kwe cancer, panzvimbo pokutarisa pakurapwa kunovandudza zviratidzo zvavo uye kuvatsigira kuti vashandise nguva yavanosara nayo.

Hapana kurapwa kwakasiyana kwakaratidzwa kunorapwa leukemia ye lymphocytic yakapinza. Asi mamwe kurapwa kwakasiyana kunogona kubatsira kudzikamisa zvinokonzerwa nekurapwa kwe cancer uye kukupa iwe kana mwana wako kunyaradza. Kurukurai sarudzo dzako nachiremba wako, sezvo mamwe kurapwa kwakasiyana angakanganisa kurapwa kwe cancer, sekunge chemotherapy.

Kurapwa kwakasiyana kunogona kudzikamisa zviratidzo kunosanganisira:

• Acupuncture
• Kuita zvemuviri
• Massage
• Kufungisisa
• Mabasa ekusununguka, anosanganisira yoga ne tai chi

Kurapwa kwe leukemia ye lymphocytic yakapinza kunogona kuva nzira refu. Kurapwa kazhinji kunogara kwemakore maviri kusvika matatu, kunyangwe mwedzi yekutanga ndiyo ine simba kwazvo.

Panguva yezvikamu zvekutsigira, vana vanogona kurarama hupenyu hunowanzova hwakanaka uye kudzokera kuchikoro. Uye vakuru vanogona kuramba vachishanda. Kuti ukubatsire kukunda, edza ku:

• Dzidza zvakakwana nezve leukemia kuti unzwe wakasununguka kuita sarudzo dzekurapwa. Kumbira chiremba wako kuti anyore ruzivo rwakawanda nezve chirwere chako chaicho. Wobva wadzikisa kutsvaga kwako ruzivo nenzira iyoyo.

Nyora mibvunzo yaunoda kubvunza chiremba wako usati wasangana naye, uye tsvaga ruzivo mubhuku rako rechikoro uye pa internet. Zvinyorwa zvakanaka zvinosanganisira National Cancer Institute, American Cancer Society, ne Leukemia & Lymphoma Society.

• Tsvaga mapurogiramu evana vane cancer. Nzvimbo huru dzekurapa nemagrupo asina purofiti anopa mabasa akawanda uye masevhisi chaiwo evana vane cancer nemhuri dzavo. Mienzaniso inosanganisira makemu ekuzorora, mapoka ekutsigira ehama nemapurogiramu ekugadzira zvido. Bvunza timu yako yekurapa nezve mapurogiramu munzvimbo yako.
• Batsira mhuri neshamwari kunzwisisa mamiriro ako. Gadzira peji rewebhu rakasununguka, rakasarudzika pane webhusaiti isina purofiti ye CaringBridge. Izvi zvinokubvumira kuti uudze mhuri yese nezvekugara uchiona, kurapwa, matambudziko nezvikonzero zvekupemberera - pasina kushushikana kwekufona munhu wese nguva dzese pane chimwe chinhu chitsva chekutaura.

Kurapa chirwere che leukemia ye lymphocytic yakapinza kunogona kuva rwendo rurefu. Kurapa kazhinji kunotora makore maviri kusvika matatu, kunyangwe mwedzi yekutanga ndiyo ine simba zvikuru. Munguva yekuchengetedza, vana vanowanzoita hupenyu hunowanzoita uye vanodzokera kuchikoro. Uye vakuru vanogona kukwanisa kuramba vachishanda. Kuti kukubatsire kubata, edza ku: Dzidza zvakakwana nezve leukemia kuti unzwe wakasununguka kuita sarudzo dzekurapa. Kumbira chiremba wako kuti anyore ruzivo rwakawanda nezve chirwere chako chaicho sezvinobvira. Wobva waderedza kutsvaga kwako ruzivo nenzira iyoyo. Nyora mibvunzo yaunoda kubvunza chiremba wako usati wasangana naye, uye tsvaga ruzivo mubhurairi yako yemuno uye pa internet. Masosi akanaka anosanganisira National Cancer Institute, American Cancer Society, ne Leukemia & Lymphoma Society. Tsigira timu yako yese yekuchengetedza utano. Kumakore makuru ezvekurapa uye kumakore ekurapa vana, timu yako yekuchengetedza utano inogona kusanganisira vanachiremba vezvepfungwa, vanachiremba vezvepfungwa, vanachiremba vezvinorwadza, vashandi vevana, vadzidzisi, vanachiremba vezvokudya, vapristi nevanoshanda vezvemagariro. Nyanzvi idzi dzinogona kubatsira nezvinhu zvakawanda, kusanganisira kutsanangura maitiro kuvana, kuwana rubatsiro rwemari uye kuronga pekugara panguva yekurapa. Usanetseka kuvimba neunyanzvi hwavo. Tsvaga mapurogiramu evana vane cancer. Makore makuru ezvekurapa nemapoka asina purofiti anopa mabasa mazhinji uye masevhisi chaiwo evana vane cancer nemhuri dzavo. Mienzaniso inosanganisira misasa yezhizha, mapoka ekutsigira ehama nemapurogiramu ekuda. Bvunza timu yako yekuchengetedza utano nezve mapurogiramu munzvimbo yako. Batsira mhuri neshamwari kunzwisisa mamiriro ako. Gadzira peji rewebhu rakasununguka, rakaenzaniswa pane webhusaiti isina purofiti yeCaringBridge. Izvi zvinokubvumira kuti uudze mhuri yese nezvekugara uchiona, kurapa, kudzoka uye zvikonzero zvekupemberera - pasina kushushikana kwekufonera munhu wese nguva dzese pane chimwe chinhu chitsva chekutaura.