Hepatitis Ye Autoimmune

Hepatitis ye autoimmune chirwere chechiropa chinoitika kana immune system yemuviri ikasvika chiropa. Izvi zvinogona kukonzera kuzvimba, kutsamwa nekukuvadzwa kwechiropa. Chikonzero chaicho chehepatitis ye autoimmune hachizivikanwe, asi zvinhu zvemagariro neezvakatipoteredza zvinoita sekubatana nekufamba kwenguva kuti zvikonzere chirwere ichi. Hepatitis ye autoimmune isina kurapwa inogona kukonzera kuita mavara echiropa, kunzi cirrhosis. Inogona zvakare pakupedzisira kukonzera kutadza kwechiropa. Zvisinei, kana yakawanikwa ichirapwa pakutanga, hepatitis ye autoimmune kazhinji inogona kudzorwa ne mishonga inodzora immune system. Kusimudzwa kwechiropa kunogona kunge kuri sarudzo kana hepatitis ye autoimmune isingapindure kune mishonga kana chirwere chechiropa chava kuenda mberi.

Zviratidzo zvehepatitis ye autoimmune zvinosiyana kubva kune munhu kuenda kune mumwe munhu uye zvinogona kuuya kamwe kamwe. Vamwe vanhu vane zvishoma, kana zvisina, matambudziko akazivikanwa mumavambo ekutanga eronda, nepo vamwe vachiona zviratidzo izvo zvinogona kusanganisira: Kuneta. Kusagadzikana kwemudumbu. Kuyerera kweganda nemaziso machena, kunonzi jaundice. Zvichienderana neruvara rweganda, shanduko iyi inogona kunge iri yakaoma kana iri nyore kuona. Chiropa chakakura. Midziyero yeropa isina kujairika paganda, inonzi spider angiomas. Kupopoma kweganda. Kurwadziwa kwemashure. Kurasikirwa nekumwedzi. Rongai musangano nemunyanzvi wehutano kana iwe uine chero zviratidzo zvinokunetsa.

Enda kunachiremba kana iwe uine zviratidzo zvinokunetsa.

Hepatitis ye autoimmune inoitika kana sisitimu yemuviri yekudzivirira, inowanzorwisa mavhairasi, mabhakitiriya nezvimwe zvinokonzera zvirwere, ichitanga kurwisa chiropa. Kurwisa uku kwechiropa kunogona kukonzera kuzvimba kwenguva refu nekukuvadzwa kwakakomba kumasero echiropa. Zvinongoitika sei kuti muviri unozvirwisa hachizivikanwi, asi vatsvakurudzi vanofunga kuti hepatitis ye autoimmune inogona kukonzerwa nekuwirirana kwemajini anotonga basa resisitimu yekudzivirira nekuiswa kune mavhairasi kana mishonga.

Nyanzvi dzakaona marudzi maviri makuru ehepatitis ye autoimmune.

• Rudzi rwe 1 autoimmune hepatitis. Iri ndiro rudzi runowanzoitika chirwere ichi. Rinogona kuitika pazera ripi zvaro. Anenge hafu yevanhu vane rudzi rwe 1 autoimmune hepatitis vane zvimwe zvirwere zve autoimmune, senge chirwere che celiac, rheumatoid arthritis kana ulcerative colitis.
• Rudzi rwe 2 autoimmune hepatitis. Kunyangwe vakuru vanogona kuwana rudzi rwe 2 autoimmune hepatitis, inowanzoitika kuvana nevakuru. Zvimwe zvirwere zve autoimmune zvinogona kuuya pamwe nerudzi urwu rwe autoimmune hepatitis.

Zvinhu zvinogona kuwedzera njodzi yako yehepatitis ye autoimmune zvinosanganisira:

• Kuve musikana. Kunyangwe varume nevakadzi vose vanogona kuwana hepatitis ye autoimmune, chirwere ichi chinowanzoitika muvakadzi.
• Genetics. Uchapupu hunoratidza kuti kuita kuti uve nehepatitis ye autoimmune kunogona kufamba mumhuri.
• Kuva nechirwere che autoimmune. Vanhu vane chirwere che autoimmune, sekudya kwe celiac, rheumatoid arthritis kana hyperthyroidism (Graves 'chirwere kana Hashimoto thyroiditis), vanogona kunge vakakurumidza kuwana hepatitis ye autoimmune.

Varices dzeesophagus ndemitsinga yakakura mu esophagus. Kazhinji dzinokonzerwa nekudzvinyirira kweropa kuburikidza neportal vein, inotakura ropa kubva mumatumbu kuenda kuchiropa.

Hepatitis ye autoimmune isingarapwi inogona kukonzera kuita mavara echigarire etishu rechiropa, inozivikanwa se cirrhosis. Zvinetso zve cirrhosis zvinosanganisira:

• Mitsinga yakakura mu esophagus, inonzi esophageal varices. Portal vein inotakura ropa kubva mumatumbu kuenda kuchiropa. Kana kuyerera kweropa kuburikidza neportal vein kuchivharwa, ropa rinogona kudzoka kumitsinga yakawanda, kunyanya iri mudumbu nemu esophagus.

  Mitsinga iyi ine masvingo matete. Uye nekuti inozadzwa neropa rakawanda kupfuura zvaifanira kutakura, inogona kubuda ropa. Kubuda ropa kwakanyanya mu esophagus kana mudumbu kubva kumitsinga iyi inyaya inotyisa inoda kurapwa nekukurumidza.

• Mvura mudumbu, inonzi ascites (uh-SY-teez). Chirwere chechiropa chinogona kukonzera mvura yakawanda kuunganidzwa mudumbu. Ascites inogona kunetsa uye inogona kukanganisa kufema. Kazhinji chiratidzo che cirrhosis yakakura.

• Kukundikana kwechiropa. Kukundikana kwechiropa kunoitika kana kukuvara kukuru kumasero echiropa kuchita kuti chiropa chisakwanise kushanda zvakanaka. Panguva ino, kuchinjwa kwechiropa kunodiwa.

• Kenza yechiropa. Vanhu vane cirrhosis vane njodzi yakawedzera yekenza yechiropa.

Mitsinga yakakura mu esophagus, inonzi esophageal varices. Portal vein inotakura ropa kubva mumatumbu kuenda kuchiropa. Kana kuyerera kweropa kuburikidza neportal vein kuchivharwa, ropa rinogona kudzoka kumitsinga yakawanda, kunyanya iri mudumbu nemu esophagus.

Mitsinga iyi ine masvingo matete. Uye nekuti inozadzwa neropa rakawanda kupfuura zvaifanira kutakura, inogona kubuda ropa. Kubuda ropa kwakanyanya mu esophagus kana mudumbu kubva kumitsinga iyi inyaya inotyisa inoda kurapwa nekukurumidza.

Biopsy yechiropa chirwere chinobvisa sampuro duku yekukura kwechiropa kuti iongororwe murabhoritari. Biopsy yechiropa kazhinji inoitirwa nekupinza tsono yakatetepa kuburikidza neganda uye mukati mechiropa.

Kuongororwa nekuita zvinoshandiswa kuona hepatitis ye autoimmune zvinosanganisira:

• Kuongororwa kweropa. Kuongorora sampuro yeropa yeantibodies kunogona kusiyanisa hepatitis ye autoimmune kubva kuhepatitis yehutachiona nemamwe mamiriro ane zviratidzo zvakafanana. Kuongororwa kweantibody kunobatsirawo kuona rudzi rwehepatitis ye autoimmune yaunayo.
• Biopsy yechiropa. Sampuro yekukura kwechiropa inogona kubviswa kuti iongorore chirwere uye kuti ione huwandu nerudzi rwekuvadza kwechiropa. Panguva yekuita biopsy, tsono yakatetepa inopfuudzwa mukati mechiropa kuburikidza nekucheka duku paganda. Tsono inoshandiswa kutora sampuro duku yekukura kwechiropa. Sampuro yacho inozotumirwa ku laboratori kuti iongororwe.

Chinangwa chekurapa chirwere chehepatitis chinokonzerwa nekuzvidzivirira ndechekudurura kana kumisa kurwiswa kwema immune system pachiropa. Izvi zvinogona kubatsira kuwedzera nguva usati chirwere chacho chakuipa. Kuti usvike chinangwa ichi, ungada mishonga inoderedza basa rema immune system. Kurapa kwekutanga kazhinji kuve prednisone. Mushonga wechipiri, azathioprine (Azasan, Imuran), unogona kukurudzirwa pamwe chete neprednisone. Prednisone, kunyanya kana ichitorwa kwenguva refu, inogona kukonzera zvirwere zvakawanda zvakakomba, kusanganisira chirwere cheshuga, mapfupa asina simba kana akaputsika, kuwedzera kweropa, cataracts, glaucoma, uye kuwedzera uremu. Vanachiremba vanowanzorayira prednisone nehuwandu hukuru kweinenge mwedzi wokutanga wekurapa. Zvadaro, kuti vderedze njodzi yezvinhu zvinokonzerwa nekuita mishonga, vanoderedza zvishoma nezvishoma huwandu hwemishonga mwedzi yakati wandei kusvika vasvika pahuwandu hwakaderera hunodzora chirwere. Kuwedzera azathioprine kunokubatsirawo kudzivirira zvinhu zvinokonzerwa neprednisone. Kunyange zvazvo ungave uine remission makore mashoma mushure mekutanga kurapwa, chirwere chinowanzo dzoka kana mushonga wakamiswa. Zvichienderana nemamiriro ako ezvinhu, ungada kurapwa kwenguva refu. Kusimudzirwa kwechiropa Kana mishonga isingamise chirwere kuti chikuipa kana uine mavara asingagone kugadziriswa — anonzi cirrhosis — kana kutadza kwechiropa, sarudzo inosara ndeyekusimudzirwa kwechiropa. Panguva yekusimudzirwa kwechiropa, chiropa chako chinorwara chinobviswa uye chinotsiviwa nechiropa chine hutano kubva kumupi. Kusimudzirwa kwechiropa kunowanzoshandisa chiropa kubva kune vanopa nhengo vakafa. Muzviitiko zvimwe, kusimudzirwa kwechiropa kubva kumupi ari mupenyu kunogona kushandiswa. Panguva yekusimudzirwa kwechiropa kubva kumupi ari mupenyu, unogamuchira chikamu chechiropa chine hutano kubva kumupi ari mupenyu. Zviropa zvose zvinotanga kugadzira masero matsva nekukurumidza. Rumwe ruzivo Kusimudzirwa kwechiropa Kumbira nguva yokuzviwonera nachiremba