Calciphylaxis
Pfupiso
Calciphylaxis (kal-sih-fuh-LAK-sis) idambudziko risingawanzoitiki, rinotyisa. Rinobatanidza kuunganidzwa kwecalcium mutsinga dzeropa diki dzematishu emafuta uye ganda.
Zviratidzo zveCalciphylaxis zvinosanganisira mavhuvhu eropa, mabundu pasi peganda uye maronda anorwadza anonzi maulcer. Kana ulcer ikatapukirwa, inogona kuva nengozi yehupenyu.
Chikonzero chaicho cheCalciphylaxis hachina kujeka. Asi vanhu vane chirwere ichi vanowanzova nekutadza kushanda kweitsvo. Ndiyo mamiriro ezvinhu umo itsvo dzisisashande sezvadzinofanira kuita. Kazhinji, vanhu ava vanogara vachiwanawo marapirwo ekutadza kushanda kweitsvo akadai sedialysis kana kuisirwa itsvo. Calciphylaxis inogona kuitika muvanhu vasina chirwere cheitsvo zvakare.
Kurapa kweCalciphylaxis kunosanganisira mishonga yakasiyana-siyana, maitiro uye kuvhiyiwa. Kurapa kunogona kubatsira kudzivirira mavhuvhu eropa uye hutachiona, kuderedza kuunganidzwa kwecalcium, kuporesa maronda, uye kurerutsa marwadzo.
Zviratidzo
Zviratidzo zveCalciphylaxis zvinosanganisira:
- Mapatani makuru akaita senet pane ganda anogona kutaridzika kuva nemuvara wemupepuru-pink.
- Zvikwambo zvakadzika, zvinorwadza paganda zvinogona kuva maronda. Maronda kazhinji ane ganda dema-brown rinorema risingapore rega. Maronda anowanzooneka munzvimbo dzine mafuta akawanda, senge mudumbu, mapapiro, matako nemazamu. Asi anogona kuumbwa chero kupi.
- Kuwanda kwehutachiona kubva kumaronda asingapore.
Zvinokonzera
Chikonzero chaicho checalciphylaxis hachizivikanwi. Hosha iyi inosanganisira kuunganidzwa kwe calcium muzvikamu zvidiki zve arteries mumafuta emuviri neganda.
Vanhu vazhinji vanowana calciphylaxis vanewo kutadza kweitsvo kana kuti vanowana dialysis. Hazvizivikanwi kuti nei vanhu vane kutadza kweitsvo kana vanhu vanowana dialysis vari panjodzi yakakura yecalciphylaxis.
Kune vamwe vanhu, kuunganidzwa kwe calcium mucalciphylaxis kunobatanidzwa nemiviri midiki mumutsipa inonzi parathyroid glands. Kana maglands aya achiburitsa maparathyroid hormones akawanda, izvozvo zvinogona kukonzera kuti calcium iunganidzwe. Asi hukama hahujeka. Vanhu vazhinji vane parathyroid glands dzinoshanda zvakanyanya havawani calciphylaxis. Uye vanhu vazhinji vane kutadza kweitsvo necalciphylaxis havafaniri kuva neparathyroid glands dzinoshanda zvakanyanya.
Zvimwe zvinhu zvinoita kunge zvine basa mucalciphylaxis zvinosanganisira:
- Kuwedzera kwekukwanisa kweropa kuti riome. Ropa rinogona kubvisa mafuta emuviri neganda oksijeni nezvokudya.
- Kuderedzwa kweropa mu arteries diki, izvo zvinogona kukonzera ma lumps eganda nemaronda.
- Kuwanda kana kuoma kwetishu, kunonziwo fibrosis.
- Kukuvadzwa kuri kuramba kuripo kwechitsitsinho chemasero anovhara midziyero yeropa. Izvi zvinonziwo vascular endothelial injury.
- Kuwedzera, kunonzi kuzvimba, mumuviri.
Zvinhu zvinokonzera njodzi
Calciphylaxis inowanzoonekwa kune vanhu vane chirwere cheitsvo. Zvimwe zvinokonzera njodzi zvinosanganisira:
- Kuzvarwa uri musikana.
- Kuonda.
- Chirwere cheshuga.
- Kufa kwechiropa, apo chiropa chinorega kushanda sezvaifanira.
- Nhoroondo yeku dialisa. Maitiro aya anobvisa tsvina nemvura yakawandisa muropa kana itsvo dzisingachagoni.
- Kuwedzera kwekukwanisa kweropa kuti riome, kunonziwo hypercoagulable state.
- Kusawirirana kwemuviri wemineral calcium kana phosphate, kana yepuroteni albumin.
- Mimwe mishonga, senge warfarin (Jantoven), calcium-binding agents ne corticosteroids.
Matambudziko
Zvinetso zveCalciphylaxis zvinosanganisira:
- Kurwadziwa kwakanyanya.
- Maronda makuru, akadzika asingarapisi ega.
- Hutachiona hweropa.
- Kufa, kunyanya nekuda kwehutachiona kana kukuvara kwezvikamu zvemuviri.
Kazhinji, tarisiro yevanhu vane calciphylaxis haina tariro. Kuwana nekurapa chero hutachiona pakutanga ndicho chinhu chikuru chekudzivirira zvinetso zvakakomba.
Kudzivirira
Hapana nzira yakajeka yekudzivirira calciphylaxis. Asi kana uri kurapwa nedialysis kana uine basa diki remakonzo nekuda kwechirwere cheitsvo chekusingaperi, zvakakosha kuchengetedza mazinga eropa e calcium ne phosphorus pasi pekutonga. Kuchengetedza mazinga eropa e phosphorus pasi pekutonga kazhinji dambudziko. Munyanzvi wehutano wako angakuda kuti utange mishonga nechikafu. Unogona zvakare kuda kudzivisa zvimwe zvekudya zvine phosphorus yakawanda. Zvakakosha kwazvo kutevera mirairo yemunyanzvi wehutano wako uye kuenda kune ese ekutarisa hutano. Kana uine calciphylaxis, timu yako yehutano inokubatsira kudzivirira hutachiona hwemavari kana zvimwe zvinetso. Ungada kushandisa zvipfeko zvakasarudzika zvemavari kana kuchenesa mavari zuva nezuva kudzivirira hutachiona hunonzi mabhakitiriya kukura.
Kuongorora
Kuongororwa kunosanganisira kuwana kana calciphylaxis ndiyo inokonzera zviratidzo zvako. Munyanzvi wehutano hwako anotarisa nhoroondo yako yehutano, anokubvunza nezvezviratidzo zvako uye anokupa bvunzo yemuviri.
Unogona zvakare kuda bvunzo dzakadai se:
- Biopsy yeganda. Panguva inoitika, munyanzvi wehutano hwako anobvisa sampuli diki yetsvina kubva munzvimbo yeganda rakabatwa. Zvadaro, laboratori inotarisa sampuli.
- Bvunzo dzeropa. Laboratori inogona kuyera zvinhu zvakasiyana-siyana muropa rako. Izvi zvinosanganisira creatinine, calcium, phosphorus, parathyroid hormone uye vitamin D. Mhedzisiro inobatsira timu yako yehutsanana kuongorora kuti itsvo dzako dziri kushanda zvakanaka sei.
- Bvunzo dzeImaging. Idzi dzinogona kubatsira kana mhedzisiro ye biopsy isiri yakajeka kana biopsy isingagone kuitwa. X-rays inogona kuratidza calcium yakawanda muropa. Kuwanda uku kunoitika kazhinji mu calciphylaxis uye mune dzimwe chirwere cheitsvo chakanyanya.
Kurapa
Kutarisa maronda kunoita basa guru pakurapa calciphylaxis. Saka zvinobatsira chaizvo kuva nechikwata chezviridzi zvemaronda.
Kuderedza kuwanda kwe calcium muma arteries kunogona kubatsirwa ne:
- Dialysis. Kana uchiita dialysis yekurapa itsvo, mushandi wehutano wako anogona kuchinja mishonga inoshandiswa uye kuti ungaita dialysis kwenguva yakareba sei uye kazhinji. Zvingabatsira kuwedzera nhamba neurefu hwema sessions e dialysis.
- Kuchinja mishonga. Mushandi wehutano wako anotarisa mishonga yako iripo uye anobvisa zvinokonzera calciphylaxis. Izvi zvinokonzera zvinosanganisira warfarin, corticosteroids uye iron. Kana uchitora calcium kana vitamin D supplements, mushandi wehutano wako anogona kuchinja huwandu hwaunotora kana kukuraira kuti urege kuitora.
- Kutora mishonga. Mushonga unonzi sodium thiosulfate unogona kuderedza kuwanda kwe calcium muma arteries madiki. Inopihwa ne tsono muvein katatu pavhiki, kazhinji panguva ye dialysis. Mushandi wehutano wako anogona kukurudzira kuti utora mushonga unonzi cinacalcet (Sensipar), unogona kubatsira kudzora parathyroid hormone (PTH). Mishonga yakawanda inogona kushandiswa kuvandudza kuenzana kwe calcium ne phosphorus mumuviri wako.
- Operation. Kana gland ye parathyroid inoshanda zvakanyanya inogadzira PTH yakawanda ichitamba basa mumamiriro ako ezvinhu, operation inogona kuva sarudzo yekurapa. Operation inonzi parathyroidectomy inogona kubvisa zvese kana chikamu cheglands dze parathyroid.
Kuti maronda apore, chimwe chezvinhu zvakakuvadzwa ne calciphylaxis zvinoda kubviswa ne operation. Izvi zvinonzi debridement. Dzimwe nguva, tishu inogona kubviswa uchishandisa nzira dzakasiyana, dzakadai sema wet dressings. Mishonga inonzi antibiotics inogona kubvisa hutachiona hunokonzerwa nemabhakitiriya. Antibiotics inogona kubatsira kurapa uye kudzivirira hutachiona hwema ulcers.
Unogona kupihwa mishonga yekudzora marwadzo nekuda kwe calciphylaxis kana panguva yekutarisa maronda. Nyanzvi yekurapa marwadzo inogona kudiwa kana wakapihwa mishonga yekurwadziwa ye opioid.